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ONTOLOGY REPORT - ANNOTATIONS


Term:Ndc80 complex
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Accession:GO:0031262 term browser browse the term
Definition:An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25.
Synonyms:exact_synonym: Nuf2-Ndc80 complex


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Ndc80 complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ndc80 NDC80 kinetochore complex component JBrowse link 9 119,837,857 119,871,435 RGD:1624291
RGD:13792537
G Nuf2 NUF2 component of NDC80 kinetochore complex JBrowse link 13 87,818,456 87,847,223 RGD:1624291
RGD:13792537
RGD:1600115
G Spc24 SPC24 component of NDC80 kinetochore complex JBrowse link 8 22,780,639 22,785,908 RGD:1624291
G Spc25 SPC25 component of NDC80 kinetochore complex JBrowse link 3 55,438,534 55,451,961 RGD:1624291
RGD:13792537
RGD:1600115

Term paths to the root
Path 1
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  cellular_component 19949
    protein-containing complex 5829
      Ndc80 complex 4
Path 2
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  cellular_component 19949
    cellular anatomical entity 19598
      organelle 12670
        non-membrane-bounded organelle 4661
          intracellular non-membrane-bounded organelle 4642
            chromosome 1109
              chromosomal region 290
                chromosome, centromeric region 186
                  kinetochore 127
                    NMS complex 4
                      Ndc80 complex 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.