ONTOLOGY REPORT - ANNOTATIONS


Term:lymphocyte costimulation
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Accession:GO:0031294 term browser browse the term
Definition:The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation.
Synonyms:exact_synonym: lymphocyte co-stimulation


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lymphocyte costimulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11252086
B cell costimulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd320 CD320 molecule JBrowse link 7 18,700,445 18,706,244 RGD:1624291
RGD:1600115
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Tnfrsf13c TNF receptor superfamily member 13C JBrowse link 7 123,453,799 123,456,289 RGD:1624291
RGD:1600115
G Tnfsf13b TNF superfamily member 13b JBrowse link 16 85,275,690 85,306,419 RGD:1624291
RGD:1600115
CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd81 Cd81 molecule JBrowse link 1 216,237,663 216,253,460 RGD:1600115
RGD:1624291
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
RGD:1600115
negative regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd160 CD160 molecule JBrowse link 2 198,933,681 198,965,380 RGD:1600115
RGD:1624291
positive regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
RGD:1600115
positive regulation of T cell costimulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr7 C-C motif chemokine receptor 7 JBrowse link 10 87,057,335 87,067,444 RGD:1624291
RGD:1600115
G Ephb4 EPH receptor B4 JBrowse link 12 22,393,338 22,418,332 RGD:1624291
G Ephb6 Eph receptor B6 JBrowse link 4 70,903,253 70,918,514 RGD:1624291
RGD:1600115
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
T cell costimulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Card11 caspase recruitment domain family, member 11 JBrowse link 12 15,700,600 15,844,512 RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1600115
RGD:1624291
G Ccl19 C-C motif chemokine ligand 19 JBrowse link 5 58,181,025 58,182,969 RGD:1624291
G Cd160 CD160 molecule JBrowse link 2 198,933,681 198,965,380 RGD:1600115
RGD:1624291
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
RGD:8554145
RGD:1600115
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1624291
RGD:13792537
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:2303155
RGD:13792537
RGD:1624291
RGD:1600115
G Cd3e CD3e molecule JBrowse link 8 49,297,604 49,309,370 RGD:1624291
RGD:1600115
G Cd5 Cd5 molecule JBrowse link 1 226,770,912 226,791,861 RGD:1624291
RGD:13792537
G Cd80 Cd80 molecule JBrowse link 11 64,815,201 64,855,293 RGD:1624291
RGD:13792537
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:13792537
G Dpp4 dipeptidylpeptidase 4 JBrowse link 3 48,291,055 48,372,672 RGD:1600115
RGD:1624291
G Efnb1 ephrin B1 JBrowse link X 68,891,227 68,904,034 RGD:1624291
RGD:1600115
G Efnb2 ephrin B2 JBrowse link 16 86,631,151 86,672,050 RGD:1624291
RGD:1600115
G Efnb3 ephrin B3 JBrowse link 10 56,161,431 56,168,819 RGD:1624291
RGD:1600115
G Hhla2 HERV-H LTR-associating 2 JBrowse link 11 53,866,424 53,875,343 RGD:1624291
G Icos inducible T-cell co-stimulator JBrowse link 9 67,748,157 67,786,808 RGD:631942
RGD:1600115
G Lgals1 galectin 1 JBrowse link 7 120,153,184 120,156,290 RGD:1624291
RGD:1600115
G Lgals8 galectin 8 JBrowse link 17 66,487,451 66,515,316 RGD:1624291
G Pdcd1lg2 programmed cell death 1 ligand 2 JBrowse link 1 247,562,202 247,629,279 RGD:13792537
G Spn sialophorin JBrowse link 1 198,572,999 198,585,664 RGD:1624291
G Tnfrsf13c TNF receptor superfamily member 13C JBrowse link 7 123,453,799 123,456,289 RGD:1624291
RGD:1600115
G Tnfrsf14 TNF receptor superfamily member 14 JBrowse link 5 172,328,259 172,337,221 RGD:1624291
G Tnfsf13b TNF superfamily member 13b JBrowse link 16 85,275,690 85,306,419 RGD:1624291
RGD:1600115
G Tnfsf14 TNF superfamily member 14 JBrowse link 9 9,761,363 9,765,461 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17896
    immune system process 2319
      lymphocyte costimulation 33
        B cell costimulation 4
        T cell costimulation + 30
Path 2
Term Annotations click to browse term
  biological_process 17896
    biological regulation 12607
      regulation of biological process 11951
        positive regulation of biological process 6148
          positive regulation of cellular process 5440
            positive regulation of cell activation 337
              positive regulation of leukocyte activation 322
                positive regulation of lymphocyte activation 267
                  lymphocyte costimulation 33
                    B cell costimulation 4
                    T cell costimulation + 30
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.