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Term:replication fork protection complex
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Accession:GO:0031298 term browser browse the term
Definition:A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling.
Synonyms:exact_synonym: replisome progression complex
 narrow_synonym: Swi1-Swi3 complex;   TIMELESS-TIPIN complex

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replication fork protection complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdc45 cell division cycle 45 JBrowse link 11 86,328,785 86,354,099 RGD:13792537
G Gins2 GINS complex subunit 2 JBrowse link 19 54,151,048 54,163,701 RGD:13792537
G Gins4 GINS complex subunit 4 JBrowse link 16 73,584,412 73,596,808 RGD:13792537
G Mcm10 minichromosome maintenance 10 replication initiation factor JBrowse link 17 77,224,218 77,245,486 RGD:13792537
G Timeless timeless circadian regulator JBrowse link 7 2,643,288 2,667,329 RGD:13792537
G Tipin timeless interacting protein JBrowse link 8 69,753,363 69,768,640 RGD:13792537
G Tipinl1 TIMELESS interacting protein like 1 JBrowse link 5 173,761 174,959 RGD:13792537
G Top1 DNA topoisomerase I JBrowse link 3 156,635,688 156,717,686 RGD:13792537
G Wdhd1 WD repeat and HMG-box DNA binding protein 1 JBrowse link 15 24,021,674 24,056,073 RGD:13792537

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Path 1
Term Annotations click to browse term
  cellular_component 19843
    protein-containing complex 5779
      replication fork protection complex 9
Path 2
Term Annotations click to browse term
  cellular_component 19843
    cellular anatomical entity 19457
      organelle 12557
        intracellular organelle 12030
          intracellular membrane-bounded organelle 9976
            nucleus 6783
              nuclear lumen 3992
                nuclear chromosome 656
                  nuclear replication fork 41
                    replication fork protection complex 9
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.