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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cell killing
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Accession:GO:0031342 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing.
Synonyms:exact_synonym: down regulation of cell killing;   downregulation of cell killing
 narrow_synonym: inhibition of cell killing


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negative regulation of complement-dependent cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59 CD59 molecule IMP RGD PMID:28212662 RGD:13792592 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cldn5 claudin 5 ISO (PMID:24280217) RGD PMID:24280217 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 IMP oligodendrocyte precursor cells RGD PMID:16135098 RGD:10448271 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Il13 interleukin 13 ISO (PMID:16034134) RGD PMID:16034134 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il4 interleukin 4 ISO
IBA
(PMID:16034134)
PMID:21873635
(PMID:16034134), (PMID:24280217)
RGD PMID:16034134, PMID:24280217, PMID:21873635 RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Jak3 Janus kinase 3 ISO (PMID:24280217) RGD PMID:24280217 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
G Stat6 signal transducer and activator of transcription 6 ISO (PMID:24280217) RGD PMID:24280217 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 ISO (MGI:MGI:5491117|PMID:23408620) RGD PMID:23408620 MGI:MGI:5491117 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 ISO (PMID:18604210) RGD PMID:18604210 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Clec12b C-type lectin domain family 12, member B ISO (PMID:17562706) RGD PMID:17562706 NCBI chr 4:163,140,883...163,157,996
Ensembl chr 4:163,141,132...163,157,744
JBrowse link
G Crk CRK proto-oncogene, adaptor protein IMP RGD PMID:18835194 RGD:11568650 NCBI chr10:63,829,731...63,855,999
Ensembl chr10:63,829,807...63,852,780
JBrowse link
G Gfer growth factor, augmenter of liver regeneration IDA RGD PMID:9021955 RGD:9685777 NCBI chr10:14,059,347...14,061,703
Ensembl chr10:14,059,347...14,061,703
JBrowse link
G Igf2 insulin-like growth factor 2 IDA RGD PMID:9021955 RGD:9685777 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Lgals9 galectin 9 ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G Mill1 MHC I like leukocyte 1 ISO (PMID:20068167) RGD PMID:20068167 NCBI chr 1:79,631,266...79,657,943
Ensembl chr 1:79,631,668...79,657,941
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 IMP RGD PMID:10837412 RGD:2313500 NCBI chr20:5,414,463...5,418,012
Ensembl chr20:5,351,605...5,421,098
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 ISO (PMID:10799855), (PMID:17179229), (PMID:23335510), (PMID:9486650) RGD PMID:9486650, PMID:10799855, PMID:17179229, PMID:23335510 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 ISO MGI:MGI:3641175 (MGI:MGI:3639618|PMID:16127454) RGD PMID:16127454 MGI:MGI:3639618 NCBI chr13:88,557,361...88,584,078
Ensembl chr13:88,557,860...88,577,691
JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 ISO
ISS
(PMID:23696226)
GO_REF:0000024
(MGI:MGI:5512785|PMID:23696226)
RGD
UniProt
PMID:23696226 GO_REF:0000024, MGI:MGI:5512785 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO (MGI:MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:MGI:5437532 NCBI chr10:31,561,838...31,590,624
Ensembl chr10:31,561,895...31,588,943
JBrowse link
G Klre1 killer cell lectin-like receptor, family E, member 1 IDA RGD PMID:12782717 RGD:1299590 NCBI chr 4:163,346,684...163,355,050
Ensembl chr 4:163,349,125...163,354,976
JBrowse link
negative regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Il7r interleukin 7 receptor ISO MGI:MGI:1857198 (MGI:MGI:893318|PMID:9215624) RGD PMID:9215624 MGI:MGI:893318
G Ppp3cb protein phosphatase 3 catalytic subunit beta ISO
IEA
MGI:MGI:2181294 (MGI:MGI:3772519|PMID:18097009)
GO_REF:0000107
RGD
Ensembl
PMID:18097009 GO_REF:0000107, MGI:MGI:3772519 NCBI chr15:4,209,702...4,236,895
Ensembl chr15:4,209,703...4,236,895
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C ISO
ISS
(MGI:MGI:3654612|PMID:9725213)
GO_REF:0000024
RGD
UniProt
PMID:9725213 GO_REF:0000024, MGI:MGI:3654612 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10232613 RGD:2303754 NCBI chr11:71,242,973...71,285,217
Ensembl chr11:71,243,334...71,284,939
JBrowse link
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec2d C-type lectin domain family 2, member D ISO MGI:MGI:107539 (MGI:MGI:2682492|PMID:12858173), (MGI:MGI:3041277|PMID:14990792), (MGI:MGI:3849756|PMID:19535641) RGD PMID:12858173, PMID:14990792, PMID:19535641 MGI:MGI:2682492, MGI:MGI:3041277, MGI:MGI:3849756 NCBI chr 4:162,278,252...162,302,881
Ensembl chr 4:162,292,305...162,302,156
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like NOT ISO (PMID:18502829)
(PMID:18502829), (PMID:8839770)
RGD PMID:8839770, PMID:18502829 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 ISO (PMID:25631937), (PMID:9754572) RGD PMID:9754572, PMID:25631937 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Serpinb3a serpin family B member 3A ISO (PMID:21857942) RGD PMID:21857942 NCBI chr13:27,153,500...27,159,319
Ensembl chr13:27,153,925...27,158,628
JBrowse link
G Serpinb9 serpin family B member 9 ISO (PMID:21795594) RGD PMID:21795594 NCBI chr17:32,648,846...32,673,047
Ensembl chr17:32,650,441...32,661,865
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:3,995,544...4,009,587
Ensembl chr20:3,995,544...4,009,587
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    cellular process 18791
      cell killing 207
        negative regulation of cell killing 31
          negative regulation of complement-dependent cytotoxicity 7
          negative regulation of killing of cells of other organism + 0
          negative regulation of leukocyte mediated cytotoxicity + 24
Path 2
Term Annotations click to browse term
  biological_process 20017
    biological regulation 13767
      regulation of biological process 13081
        regulation of cellular process 12570
          regulation of cell killing 110
            negative regulation of cell killing 31
              negative regulation of complement-dependent cytotoxicity 7
              negative regulation of killing of cells of other organism + 0
              negative regulation of leukocyte mediated cytotoxicity + 24
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.