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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of defense response
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Accession:GO:0031348 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.
Synonyms:exact_synonym: down regulation of defense response;   downregulation of defense response
 narrow_synonym: inhibition of defense response


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negative regulation of acute inflammatory response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO RGD PMID:2167912 RGD:5129103 NCBI chrNW_004936567:1,430,128...1,508,626 JBrowse link
G Ash1l ASH1 like histone lysine methyltransferase ISO (MGI:MGI:5562489|PMID:24012418) MGI PMID:24012418 MGI:MGI:5562489 NCBI chrNW_004936580:4,821,384...4,997,112 JBrowse link
G Il4 interleukin 4 ISO RGD PMID:17250684 RGD:2317298 NCBI chrNW_004936647:2,510,457...2,518,576 JBrowse link
G Ins insulin ISO (PMID:11443198) BHF-UCL PMID:11443198 NCBI chrNW_004936816:1,002,137...1,003,357 JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 ISO (PMID:11687797) BHF-UCL PMID:11687797 NCBI chrNW_004936864:709,693...732,119 JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO RGD PMID:18479673 RGD:2301881 NCBI chrNW_004936602:1,230,907...1,368,588 JBrowse link
negative regulation of acute inflammatory response to antigenic stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 ISO RGD PMID:17698245 RGD:2325282 NCBI chrNW_004936672:3,461,387...3,468,053 JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb ISO (MGI:MGI:3608295|PMID:12385742) MGI PMID:12385742 MGI:MGI:3608295 NCBI chrNW_004937131:80,014...96,114 JBrowse link
G Npy neuropeptide Y ISO RGD PMID:18805447 RGD:10448932 NCBI chrNW_004936478:1,289,437...1,296,819 JBrowse link
G Npy5r neuropeptide Y receptor Y5 ISO RGD PMID:18805447 RGD:10448932 NCBI chrNW_004936555:2,248,699...2,252,637 JBrowse link
G Selenos selenoprotein S ISO (PMID:18675776) BHF-UCL PMID:18675776 NCBI chrNW_004936483:2,589,773...2,600,837 JBrowse link
negative regulation of acute inflammatory response to non-antigenic stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 ISO RGD PMID:20229361 RGD:2325270 NCBI chrNW_004936672:3,461,387...3,468,053 JBrowse link
negative regulation of antibacterial peptide production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor Kazal type 5 ISO (MGI:MGI:3770082|PMID:17012259) UniProtKB PMID:17012259 MGI:MGI:3770082 NCBI chrNW_004936504:6,653,703...6,750,110 JBrowse link
negative regulation of antifungal innate immune response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fam3a FAM3 metabolism regulating signaling molecule A ISO (PMID:18212107) UniProtKB PMID:18212107 NCBI chrNW_004936809:1,248,865...1,258,894 JBrowse link
negative regulation of astrocyte activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor ISO (MGI:MGI:4415751|PMID:20005821) ARUK-UCL PMID:20005821 MGI:MGI:4415751 NCBI chrNW_004936659:1,259,405...1,300,545 JBrowse link
G Nr1d1 nuclear receptor subfamily 1 group D member 1 ISO (MGI:MGI:6283959|PMID:30792350) UniProt PMID:30792350 MGI:MGI:6283959 NCBI chrNW_004936490:15,206,194...15,213,858 JBrowse link
negative regulation of behavioral fear response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cck cholecystokinin ISO RGD PMID:12450740 RGD:1626100 NCBI chrNW_004936695:2,776,705...2,782,280 JBrowse link
negative regulation of chronic inflammatory response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 ISO (MGI:MGI:3693968|PMID:16769892)
(MGI:MGI:3695768|PMID:16275384)
MGI PMID:16275384, PMID:16769892 MGI:MGI:3693968, MGI:MGI:3695768 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Il4 interleukin 4 ISO RGD PMID:16869003 RGD:2317300 NCBI chrNW_004936647:2,510,457...2,518,576 JBrowse link
G LOC101954950 aromatase ISO (MGI:MGI:5610078|PMID:25447050) MGI PMID:25447050 MGI:MGI:5610078 NCBI chrNW_004936471:13,107,603...13,136,910 JBrowse link
G Tnfaip3 TNF alpha induced protein 3 ISO (MGI:MGI:3763997|PMID:18006655) BHF-UCL PMID:18006655 MGI:MGI:3763997 NCBI chrNW_004936560:5,124,955...5,138,988 JBrowse link
negative regulation of chronic inflammatory response to antigenic stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 ISO (MGI:MGI:3774790|PMID:12452830) MGI PMID:12452830 MGI:MGI:3774790 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
negative regulation of chronic inflammatory response to non-antigenic stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:24447880 RGD:9491776 NCBI chrNW_004936473:28,508,726...28,535,640 JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule ISO (PMID:9029106) AgBase PMID:9029106 NCBI chrNW_004936557:5,136,784...5,175,543 JBrowse link
G Cr1 complement C3b/C4b receptor 1 (Knops blood group) ISO (PMID:10531307) UniProtKB PMID:10531307 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
G Susd4 sushi domain containing 4 ISO (PMID:23482636) UniProtKB PMID:23482636 NCBI chrNW_004936526:488,604...615,265 JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 ISO (PMID:17051150) UniProt PMID:17051150 NCBI chrNW_004936635:2,167,633...2,191,725 JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin ISO (PMID:12538697) UniProtKB PMID:12538697 NCBI chrNW_004936870:424,832...468,303 JBrowse link
G Serping1 serpin family G member 1 ISO (PMID:10946292) UniProtKB PMID:10946292 NCBI chrNW_004936581:4,911,403...4,924,484 JBrowse link
negative regulation of connective tissue replacement involved in inflammatory response wound healing term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor ISO (MGI:MGI:3774727|PMID:18245812) MGI PMID:18245812 MGI:MGI:3774727 NCBI chrNW_004936727:1,418,342...1,422,005 JBrowse link
negative regulation of cytokine production involved in inflammatory response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 ISO (MGI:MGI:3836690|PMID:18723473) UniProtKB PMID:18723473 MGI:MGI:3836690 NCBI chrNW_004936809:615,133...634,618 JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 ISO (MGI:MGI:3836690|PMID:18723473) UniProtKB PMID:18723473 MGI:MGI:3836690 NCBI chrNW_004936607:1,292,964...1,345,671 JBrowse link
G Adcy7 adenylate cyclase 7 ISO (MGI:MGI:4459338|PMID:20505140) UniProtKB PMID:20505140 MGI:MGI:4459338 NCBI chrNW_004936475:3,368,069...3,393,306 JBrowse link
G Apod apolipoprotein D ISO (PMID:18842892) UniProtKB PMID:18842892 NCBI chrNW_004936833:260,798...277,060 JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 ISO (MGI:MGI:5698780|PMID:25328665) UniProt PMID:25328665 MGI:MGI:5698780 NCBI chrNW_004936492:9,477,483...9,526,692 JBrowse link
G Chid1 chitinase domain containing 1 ISO (PMID:20724479) UniProtKB PMID:20724479 NCBI chrNW_004936888:619,579...648,650 JBrowse link
G Cuedc2 CUE domain containing 2 ISO (PMID:24882011)
(MGI:MGI:5576401|PMID:24882011)
MGI PMID:24882011 MGI:MGI:5576401 NCBI chrNW_004936600:3,439,385...3,445,731 JBrowse link
G F2 coagulation factor II, thrombin ISO (PMID:20421939) UniProtKB PMID:20421939 NCBI chrNW_004936562:2,371,725...2,388,617 JBrowse link
G Il1r2 interleukin 1 receptor type 2 ISO (MGI:MGI:5468848|PMID:23395675) MGI PMID:23395675 MGI:MGI:5468848 NCBI chrNW_004936713:679,680...716,801 JBrowse link
G LOC101960864 group 10 secretory phospholipase A2 ISO (MGI:MGI:5779244|PMID:26828067) MGI PMID:26828067 MGI:MGI:5779244 NCBI chrNW_004936501:2,841,209...2,857,570 JBrowse link
G Macir macrophage immunometabolism regulator ISO (MGI:MGI:5698579|PMID:26316022) MGI PMID:26316022 MGI:MGI:5698579 NCBI chrNW_004936523:1,273,812...1,292,837 JBrowse link
G Mefv MEFV innate immuity regulator, pyrin ISO (PMID:26347139) UniProtKB PMID:26347139 NCBI chrNW_004936694:970,706...980,605 JBrowse link
G Nlrc3 NLR family CARD domain containing 3 ISO (MGI:MGI:5568884|PMID:24560620) UniProtKB PMID:24560620 MGI:MGI:5568884 NCBI chrNW_004936694:757,121...773,924 JBrowse link
G Pdcd4 programmed cell death 4 ISO (MGI:MGI:3707264|PMID:17114484), (MGI:MGI:4438829|PMID:19946272) BHF-UCL PMID:17114484, PMID:19946272 MGI:MGI:3707264, MGI:MGI:4438829 NCBI chrNW_004936486:1,684,167...1,705,387 JBrowse link
G Pycard PYD and CARD domain containing ISO (PMID:24531343) UniProt PMID:24531343 NCBI chrNW_004936501:13,550,702...13,552,774 JBrowse link
G Sirpa signal regulatory protein alpha ISO (MGI:MGI:3760575|PMID:17954568)
(MGI:MGI:6189251|PMID:23562609)
ARUK-UCL PMID:17954568, PMID:23562609 MGI:MGI:3760575, MGI:MGI:6189251 NCBI chrNW_004936485:16,608,317...16,654,552 JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A ISO (MGI:MGI:5142149|PMID:21616078) UniProtKB PMID:21616078 MGI:MGI:5142149 NCBI chrNW_004936474:19,714,145...19,722,512 JBrowse link
negative regulation of defense response to bacterium term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 ISO (MGI:MGI:5908771|PMID:27074721) UniProtKB PMID:27074721 MGI:MGI:5908771 NCBI chrNW_004936495:11,004,296...11,045,467 JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO (MGI:MGI:5437532|PMID:22842346) UniProtKB PMID:22842346 MGI:MGI:5437532 NCBI chrNW_004936515:6,001,324...6,015,407 JBrowse link
G Mapkbp1 mitogen-activated protein kinase binding protein 1 ISO (PMID:22700971) UniProtKB PMID:22700971 NCBI chrNW_004936471:5,078,259...5,135,937 JBrowse link
G Sirt2 sirtuin 2 ISO (MGI:MGI:5502462|PMID:23908241)
(PMID:23908241)
UniProtKB PMID:23908241 MGI:MGI:5502462 NCBI chrNW_004936661:1,828,868...1,849,892 JBrowse link
negative regulation of defense response to virus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein ISO (PMID:19164550) UniProtKB PMID:19164550 NCBI chrNW_004936677:2,371,400...2,376,608 JBrowse link
G Fgl2 fibrinogen like 2 ISO (MGI:MGI:6188369|PMID:29341118) MGI PMID:29341118 MGI:MGI:6188369 NCBI chrNW_004936479:20,619,955...20,625,416 JBrowse link
G Foxp3 forkhead box P3 ISO RGD PMID:17878294 RGD:2325989 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Htra1 HtrA serine peptidase 1 ISO RGD PMID:15333144 RGD:2311622 NCBI chrNW_004936486:11,271,130...11,317,271 JBrowse link
G Ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains ISO (PMID:29802199) UniProt PMID:29802199 NCBI chrNW_004936476:24,448,402...24,536,163 JBrowse link
G Itch itchy E3 ubiquitin protein ligase ISO (PMID:19881509)
(MGI:MGI:4436832|PMID:19881509)
UniProtKB PMID:19881509 MGI:MGI:4436832 NCBI chrNW_004936561:6,140,236...6,265,734 JBrowse link
G Pcbp2 poly(rC) binding protein 2 ISO (PMID:19881509) UniProtKB PMID:19881509 NCBI chrNW_004936512:10,732,129...10,754,885 JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent 1B ISO (PMID:22750291) UniProtKB PMID:22750291 NCBI chrNW_004936508:7,732,724...7,804,964 JBrowse link
G Rnf26 ring finger protein 26 ISO (PMID:25254379) UniProtKB PMID:25254379 NCBI chrNW_004936542:4,265,226...4,268,037 JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 ISO (MGI:MGI:5306204|PMID:22079989)
(PMID:22079989)
MGI
CACAO
PMID:22079989 MGI:MGI:5306204 NCBI chrNW_004936525:115,614...174,641 JBrowse link
G Trim38 tripartite motif containing 38 ISO (MGI:MGI:5441682|PMID:22539786) MGI PMID:22539786 MGI:MGI:5441682 NCBI chrNW_004936671:1,841,722...1,853,804 JBrowse link
negative regulation of defense response to virus by host term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf3 interferon regulatory factor 3 ISO (MGI:MGI:3828224|PMID:18851954) MGI PMID:18851954 MGI:MGI:3828224 NCBI chrNW_004936664:3,477,750...3,482,489 JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 ISO (PMID:23399697) UniProtKB PMID:23399697 NCBI chrNW_004936474:6,479,640...6,486,080 JBrowse link
G Tarbp2 TARBP2 subunit of RISC loading complex ISO (PMID:11641396) UniProtKB PMID:11641396 NCBI chrNW_004936512:10,774,793...10,780,041 JBrowse link
negative regulation of inflammatory response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 ISO (MGI:MGI:5490396|PMID:23609450) UniProtKB PMID:23609450 MGI:MGI:5490396 NCBI chrNW_004936511:4,322,198...4,326,562 JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant ISO (MGI:MGI:1930064|PMID:11168643) MGI PMID:11168643 MGI:MGI:1930064 NCBI chrNW_004936659:1,598,252...1,642,615 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO (MGI:MGI:3822392|PMID:19109165) UniProtKB PMID:19109165 MGI:MGI:3822392 NCBI chrNW_004936578:3,168,599...3,179,369 JBrowse link
G Adora1 adenosine A1 receptor ISO (MGI:MGI:3525377|PMID:15630442) MGI PMID:15630442 MGI:MGI:3525377 NCBI chrNW_004936567:1,430,128...1,508,626 JBrowse link
G Adora2a adenosine A2a receptor ISO (MGI:MGI:3765393|PMID:17601796) MGI PMID:17601796 MGI:MGI:3765393 NCBI chrNW_004936619:597,970...618,564 JBrowse link
G Adrb2 adrenoceptor beta 2 ISO RGD PMID:15285793 RGD:1598753 NCBI chrNW_004936504:5,985,407...5,987,453 JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO (PMID:21206090) UniProt PMID:21206090 NCBI chrNW_004936554:7,807,914...7,848,691 JBrowse link
G Aoah acyloxyacyl hydrolase ISO (MGI:MGI:3042753|PMID:15155618) MGI PMID:15155618 MGI:MGI:3042753 NCBI chrNW_004936478:11,971,103...12,174,489 JBrowse link
G Apoa1 apolipoprotein A1 ISO (PMID:21571275) BHF-UCL PMID:21571275 NCBI chrNW_004936542:2,111,055...2,112,626 JBrowse link
G Apoe apolipoprotein E ISO (MGI:MGI:5301204|PMID:21784977) UniProtKB PMID:21784977 MGI:MGI:5301204 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Ash1l ASH1 like histone lysine methyltransferase ISO (MGI:MGI:5562489|PMID:24012418) MGI PMID:24012418 MGI:MGI:5562489 NCBI chrNW_004936580:4,821,384...4,997,112 JBrowse link
G Bcr BCR activator of RhoGEF and GTPase ISO (MGI:MGI:4366690|PMID:19703997) MGI PMID:19703997 MGI:MGI:4366690 NCBI chrNW_004936619:288,377...432,297 JBrowse link
G C1qtnf12 C1q and TNF related 12 ISO (MGI:MGI:5295524|PMID:21849507) MGI PMID:21849507 MGI:MGI:5295524 NCBI chrNW_004936737:1,877,428...1,881,345 JBrowse link
G C1qtnf3 C1q and TNF related 3 ISO (PMID:16213490) UniProtKB PMID:16213490 NCBI chrNW_004936518:7,039,590...7,060,463 JBrowse link
G Calcrl calcitonin receptor like receptor ISO RGD PMID:17363466 RGD:1625357 NCBI chrNW_004936506:10,191,789...10,292,355 JBrowse link
G Ccn3 cellular communication network factor 3 ISO (MGI:MGI:5604651|PMID:24722330) UniProtKB PMID:24722330 MGI:MGI:5604651 NCBI chrNW_004936470:27,178,439...27,185,554 JBrowse link
G Cd276 CD276 molecule ISO (MGI:MGI:2671029|PMID:12925852) MGI PMID:12925852 MGI:MGI:2671029 NCBI chrNW_004936471:32,864,778...32,892,044 JBrowse link
G Cd44 CD44 molecule (Indian blood group) ISO (MGI:MGI:5688819|PMID:25065622) UniProtKB PMID:25065622 MGI:MGI:5688819 NCBI chrNW_004936533:2,949,026...3,033,166 JBrowse link
G Cdh5 cadherin 5 ISO (PMID:28112401) BHF-UCL PMID:28112401 NCBI chrNW_004936475:16,738,772...16,775,000 JBrowse link
G Cnr2 cannabinoid receptor 2 ISO RGD PMID:20067581 RGD:2316187 NCBI chrNW_004936474:9,019,044...9,020,110 JBrowse link
G Cxcl17 C-X-C motif chemokine ligand 17 ISO (PMID:23115081) UniProtKB PMID:23115081 NCBI chrNW_004936706:62,417...119,278 JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 ISO (MGI:MGI:5660449|PMID:25692702) UniProtKB PMID:25692702 MGI:MGI:5660449 NCBI chrNW_004937067:41,573...129,386 JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor ISO (MGI:MGI:5619451|PMID:22294049) CACAO PMID:22294049 MGI:MGI:5619451 NCBI chrNW_004936572:3,728,971...3,795,612 JBrowse link
G Fem1a fem-1 homolog A ISO (PMID:16424369)
(MGI:MGI:3790904|PMID:18270204)
UniProtKB
MGI
PMID:16424369, PMID:18270204 MGI:MGI:3790904 NCBI chrNW_004936588:2,808,561...2,811,738 JBrowse link
G Ffar4 free fatty acid receptor 4 ISO (MGI:MGI:4839696|PMID:20813258) UniProtKB PMID:20813258 MGI:MGI:4839696 NCBI chrNW_004936601:1,413,236...1,434,036 JBrowse link
G Fndc4 fibronectin type III domain containing 4 ISO (MGI:MGI:5810052|PMID:27066907) UniProtKB PMID:27066907 MGI:MGI:5810052 NCBI chrNW_004936493:5,103,613...5,106,755 JBrowse link
G Foxf1 forkhead box F1 ISO (MGI:MGI:4367570|PMID:18421012) MGI PMID:18421012 MGI:MGI:4367570 NCBI chrNW_004943883:4...1,756 JBrowse link
G Foxp3 forkhead box P3 ISO (MGI:MGI:3607665|PMID:16203996) MGI PMID:16203996 MGI:MGI:3607665 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Gata3 GATA binding protein 3 ISO (PMID:19674970) UniProtKB PMID:19674970 NCBI chrNW_004936484:6,780,692...6,800,883 JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO (PMID:15232612) UniProtKB PMID:15232612 NCBI chrNW_004936602:3,037,862...3,044,863 JBrowse link
G Ghsr growth hormone secretagogue receptor ISO (PMID:15232612) UniProtKB PMID:15232612 NCBI chrNW_004936593:268,736...273,623 JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 ISO (PMID:23285008) UniProtKB PMID:23285008 NCBI chrNW_004936754:1,288,891...1,293,555 JBrowse link
G Gpr31 G protein-coupled receptor 31 ISO (MGI:MGI:6377747|PMID:29227475) UniProt PMID:29227475 MGI:MGI:6377747 NCBI chrNW_004936489:16,702,024...16,703,000 JBrowse link
G Gps2 G protein pathway suppressor 2 ISO (MGI:MGI:6148454|PMID:22424771) UniProtKB PMID:22424771 MGI:MGI:6148454 NCBI chrNW_004936595:608,730...611,871 JBrowse link
G Grn granulin precursor ISO (MGI:MGI:4421471|PMID:20026663) UniProt PMID:20026663 MGI:MGI:4421471 NCBI chrNW_004936541:793,548...800,271 JBrowse link
G Hamp hepcidin antimicrobial peptide ISO (MGI:MGI:4829573|PMID:20530874) MGI PMID:20530874 MGI:MGI:4829573 NCBI chrNW_004936570:1,009,344...1,010,654 JBrowse link
G Hgf hepatocyte growth factor ISO (MGI:MGI:4849876|PMID:21072211) MGI PMID:21072211 MGI:MGI:4849876 NCBI chrNW_004936734:354,798...428,356 JBrowse link
G Ier3 immediate early response 3 ISO (MGI:MGI:4430982|PMID:19923449) MGI PMID:19923449 MGI:MGI:4430982 NCBI chrNW_004936837:401,475...402,769 JBrowse link
G Il10 interleukin 10 ISO (MGI:MGI:3790904|PMID:18270204)
(PMID:10443688)
RGD
MGI
BHF-UCL
PMID:10443688, PMID:17017555, PMID:18270204 MGI:MGI:3790904, RGD:1598631 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il13 interleukin 13 ISO (PMID:30634164) ARUK-UCL PMID:30634164 NCBI chrNW_004936647:2,529,933...2,532,503 JBrowse link
G Il2 interleukin 2 ISO (MGI:MGI:63352|PMID:8402910), (MGI:MGI:87442|PMID:7589135) MGI PMID:7589135, PMID:8402910 MGI:MGI:63352, MGI:MGI:87442 NCBI chrNW_004936662:1,594,953...1,599,625 JBrowse link
G Il22 interleukin 22 ISO (MGI:MGI:5444766|PMID:23075849) MGI PMID:23075849 MGI:MGI:5444766 NCBI chrNW_004936545:6,227,118...6,231,745 JBrowse link
G Il22ra2 interleukin 22 receptor subunit alpha 2 ISO (MGI:MGI:5444766|PMID:23075849) MGI PMID:23075849 MGI:MGI:5444766 NCBI chrNW_004936560:4,493,279...4,506,973 JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO (MGI:MGI:1889048|PMID:7584142), (MGI:MGI:2670301|PMID:12702495) MGI PMID:7584142, PMID:12702495 MGI:MGI:1889048, MGI:MGI:2670301 NCBI chrNW_004936484:8,514,333...8,555,392 JBrowse link
G Il4 interleukin 4 ISO (PMID:30634164) ARUK-UCL PMID:30634164 NCBI chrNW_004936647:2,510,457...2,518,576 JBrowse link
G Isl1 ISL LIM homeobox 1 ISO (MGI:MGI:5437583|PMID:22727192) BHF-UCL PMID:22727192 MGI:MGI:5437583 NCBI chrNW_004936480:15,805,259...15,817,854 JBrowse link
G Krt1 keratin 1 ISO (MGI:MGI:5507924|PMID:23132931) MGI PMID:23132931 MGI:MGI:5507924 NCBI chrNW_004936512:10,084,764...10,090,312 JBrowse link
G Lgals9 galectin 9 ISO (MGI:MGI:5688819|PMID:25065622) UniProtKB PMID:25065622 MGI:MGI:5688819 NCBI chrNW_004936538:4,034,467...4,050,240 JBrowse link
G LOC101958024 submaxillary mucin-like protein ISO (MGI:MGI:1340065|PMID:10393849), (MGI:MGI:1858380|PMID:10793067), (MGI:MGI:68460|PMID:8077681), (MGI:MGI:82279|PMID:8806790), (MGI:MGI:87148|PMID:9110981)
(MGI:MGI:2384231|PMID:12163455)
MGI PMID:8077681, PMID:8806790, PMID:9110981, PMID:10393849, PMID:10793067, PMID:12163455 MGI:MGI:1340065, MGI:MGI:1858380, MGI:MGI:2384231, MGI:MGI:68460, MGI:MGI:82279, MGI:MGI:87148 NCBI chrNW_004936607:418,290...443,988 JBrowse link
G LOC101960864 group 10 secretory phospholipase A2 ISO (MGI:MGI:5779244|PMID:26828067) MGI PMID:26828067 MGI:MGI:5779244 NCBI chrNW_004936501:2,841,209...2,857,570 JBrowse link
G LOC101976167 active breakpoint cluster region-related protein ISO (MGI:MGI:4366690|PMID:19703997) MGI PMID:19703997 MGI:MGI:4366690 NCBI chrNW_004936538:6,674,595...6,819,511 JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 ISO (MGI:MGI:5548036|PMID:24206663) UniProt PMID:24206663 MGI:MGI:5548036 NCBI chrNW_004936709:800,197...852,659 JBrowse link
G Lrfn5 leucine rich repeat and fibronectin type III domain containing 5 ISO (PMID:27152329) UniProt PMID:27152329 NCBI chrNW_004936494:14,908,783...15,155,797 JBrowse link
G Macir macrophage immunometabolism regulator ISO (PMID:30659109) UniProt PMID:30659109 NCBI chrNW_004936523:1,273,812...1,292,837 JBrowse link
G Mefv MEFV innate immuity regulator, pyrin ISO (PMID:16403826) BHF-UCL PMID:16403826 NCBI chrNW_004936694:970,706...980,605 JBrowse link
G Metrnl meteorin like, glial cell differentiation regulator ISO (MGI:MGI:5574515|PMID:24906147) UniProtKB PMID:24906147 MGI:MGI:5574515 NCBI chrNW_004936923:423,618...442,261 JBrowse link
G Mfhas1 malignant fibrous histiocytoma amplified sequence 1 ISO (PMID:29168081) UniProtKB PMID:29168081 NCBI chrNW_004936573:1,567,798...1,662,442 JBrowse link
G Mvk mevalonate kinase ISO (PMID:16732551) BHF-UCL PMID:16732551 NCBI chrNW_004936769:1,274,595...1,295,186 JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 ISO (MGI:MGI:3694584|PMID:17137798) MGI PMID:17137798 MGI:MGI:3694584 NCBI chrNW_004936504:12,053,470...12,103,346 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 ISO (MGI:MGI:3790904|PMID:18270204) MGI PMID:18270204 MGI:MGI:3790904 NCBI chrNW_004936520:733,760...850,563 JBrowse link
G Nlrc3 NLR family CARD domain containing 3 ISO (PMID:25277106)
(MGI:MGI:5568884|PMID:24560620)
UniProtKB PMID:24560620, PMID:25277106 MGI:MGI:5568884 NCBI chrNW_004936694:757,121...773,924 JBrowse link
G Nlrp12 NLR family pyrin domain containing 12 ISO (PMID:18230725)
(MGI:MGI:6285057|PMID:30212649)
BHF-UCL
UniProt
PMID:18230725, PMID:30212649 MGI:MGI:6285057 NCBI chrNW_004936994:20,848...36,757 JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 ISO (PMID:12483741), (PMID:16531551), (PMID:17178985) BHF-UCL PMID:12483741, PMID:16531551, PMID:17178985 NCBI chrNW_004936864:709,693...732,119 JBrowse link
G Nlrx1 NLR family member X1 ISO (MGI:MGI:5050761|PMID:21703540) MGI PMID:21703540 MGI:MGI:5050761 NCBI chrNW_004936542:4,105,980...4,121,176 JBrowse link
G Nr1d1 nuclear receptor subfamily 1 group D member 1 ISO (MGI:MGI:6162161|PMID:29533925) UniProt PMID:29533925 MGI:MGI:6162161 NCBI chrNW_004936490:15,206,194...15,213,858 JBrowse link
G Nr1d2 nuclear receptor subfamily 1 group D member 2 ISO (MGI:MGI:6162161|PMID:29533925) UniProt PMID:29533925 MGI:MGI:6162161 NCBI chrNW_004936473:15,624,597...15,646,875 JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 ISO (MGI:MGI:5009771|PMID:21187453) BHF-UCL PMID:21187453 MGI:MGI:5009771 NCBI chrNW_004936562:1,937,665...1,946,680 JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 ISO (MGI:MGI:5707586|PMID:18972444) UniProtKB PMID:18972444 MGI:MGI:5707586 NCBI chrNW_004936492:13,315,265...13,365,186 JBrowse link
G Nt5e 5'-nucleotidase ecto ISO (MGI:MGI:3770326|PMID:16547283) MGI PMID:16547283 MGI:MGI:3770326 NCBI chrNW_004936510:5,797,218...5,846,118 JBrowse link
G Otulin OTU deubiquitinase with linear linkage specificity ISO (PMID:23806334), (PMID:27523608), (PMID:27559085)
(MGI:MGI:5804663|PMID:27523608), (MGI:MGI:6192867|PMID:29950720)
UniProtKB
UniProt
PMID:23806334, PMID:27523608, PMID:27559085, PMID:29950720 MGI:MGI:5804663, MGI:MGI:6192867 NCBI chrNW_004936665:1,654,045...1,690,955 JBrowse link
G Pbk PDZ binding kinase ISO (MGI:MGI:5293269|PMID:21715333) MGI PMID:21715333 MGI:MGI:5293269 NCBI chrNW_004936675:704,001...722,769 JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 ISO (MGI:MGI:5297103|PMID:19218085) MGI PMID:19218085 MGI:MGI:5297103 NCBI chrNW_004936706:2,317,137...2,320,993 JBrowse link
G Pla2g5 phospholipase A2 group V ISO (MGI:MGI:5605113|PMID:24910243) MGI PMID:24910243 MGI:MGI:5605113 NCBI chrNW_004936474:6,131,915...6,150,810 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO (PMID:21636785) BHF-UCL PMID:21636785 NCBI chrNW_004936629:3,672,445...3,725,645 JBrowse link
G Ppard peroxisome proliferator activated receptor delta ISO RGD PMID:17461989 RGD:2324886 NCBI chrNW_004936476:23,799,285...23,886,606 JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa ISO (PMID:25651845) UniProtKB PMID:25651845 NCBI chrNW_004936469:43,841,989...43,850,322 JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO (PMID:16424369)
(MGI:MGI:3790904|PMID:18270204)
UniProtKB
MGI
PMID:16424369, PMID:18270204 MGI:MGI:3790904 NCBI chrNW_004936518:1,903,636...1,916,746 JBrowse link
G Ptgis prostaglandin I2 synthase ISO (PMID:20159982) UniProtKB PMID:20159982 NCBI chrNW_004936514:4,775,884...4,814,574 JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 ISO (MGI:MGI:3044093|PMID:14726372) UniProtKB PMID:14726372 MGI:MGI:3044093 NCBI chrNW_004936626:2,390,004...2,472,039 JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 ISO (MGI:MGI:3050742|PMID:15235600) MGI PMID:15235600 MGI:MGI:3050742 NCBI chrNW_004936543:7,405,070...7,447,940 JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO (MGI:MGI:6112863|PMID:29304157) BHF-UCL PMID:29304157 MGI:MGI:6112863 NCBI chrNW_004936565:1,596,227...1,746,706 JBrowse link
G Rora RAR related orphan receptor A ISO (PMID:11252722) UniProtKB PMID:11252722 NCBI chrNW_004936471:21,402,056...21,567,908 JBrowse link
G Serpinf1 serpin family F member 1 ISO RGD PMID:16368716 RGD:1580133 NCBI chrNW_004936538:7,885,816...7,898,308 JBrowse link
G Sharpin SHANK associated RH domain interactor ISO (MGI:MGI:4947438|PMID:21455180), (MGI:MGI:4947439|PMID:21455173) UniProtKB PMID:21455173, PMID:21455180 MGI:MGI:4947438, MGI:MGI:4947439 NCBI chrNW_004936470:8,076,605...8,081,872 JBrowse link
G Sirpa signal regulatory protein alpha ISO (PMID:24026300) ARUK-UCL PMID:24026300 NCBI chrNW_004936485:16,608,317...16,654,552 JBrowse link
G Slit2 slit guidance ligand 2 ISO RGD PMID:15215188 RGD:2316132 NCBI chrNW_004936477:8,111,212...8,448,567 JBrowse link
G Slpi secretory leukocyte peptidase inhibitor ISO RGD PMID:10449524 RGD:634208 NCBI chrNW_004936514:7,618,382...7,620,790 JBrowse link
G Smad3 SMAD family member 3 ISO (MGI:MGI:1352043|PMID:10559937) UniProtKB PMID:10559937 MGI:MGI:1352043 NCBI chrNW_004936471:27,080,662...27,185,861 JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase acid like 3B ISO (MGI:MGI:5689225|PMID:26095358) UniProtKB PMID:26095358 MGI:MGI:5689225 NCBI chrNW_004936474:12,158,628...12,179,993 JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO (MGI:MGI:4829573|PMID:20530874) MGI PMID:20530874 MGI:MGI:4829573 NCBI chrNW_004936594:2,932,297...2,935,358 JBrowse link
G Socs5 suppressor of cytokine signaling 5 ISO (MGI:MGI:5659826|PMID:24255059) BHF-UCL PMID:24255059 MGI:MGI:5659826 NCBI chrNW_004936508:5,531,002...5,588,022 JBrowse link
G Sod1 superoxide dismutase 1 ISO (MGI:MGI:6271924|PMID:25381879) ARUK-UCL PMID:25381879 MGI:MGI:6271924 NCBI chrNW_004936500:10,345,154...10,352,873 JBrowse link
G Tnfaip3 TNF alpha induced protein 3 ISO (MGI:MGI:5490396|PMID:23609450)
(MGI:MGI:4946158|PMID:21088135)
UniProtKB
BHF-UCL
PMID:21088135, PMID:23609450 MGI:MGI:4946158, MGI:MGI:5490396 NCBI chrNW_004936560:5,124,955...5,138,988 JBrowse link
G Tnfaip6 TNF alpha induced protein 6 ISO (PMID:21569482) CACAO PMID:21569482 NCBI chrNW_004936469:26,129,339...26,145,464 JBrowse link
G Tnfaip8l2 TNF alpha induced protein 8 like 2 ISO (MGI:MGI:5007605|PMID:21466895) MGI PMID:21466895 MGI:MGI:5007605 NCBI chrNW_004936580:1,357,076...1,360,233 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO (PMID:13130484) BHF-UCL PMID:13130484 NCBI chrNW_004936709:1,407,327...1,421,448 JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO (MGI:MGI:2152007|PMID:11588035) MGI PMID:11588035 MGI:MGI:2152007 NCBI chrNW_004936474:908,414...935,765 JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase ISO (MGI:MGI:3773763|PMID:18083102) UniProtKB PMID:18083102 MGI:MGI:3773763 NCBI chrNW_004936471:4,893,185...4,910,779 JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats ISO (MGI:MGI:3041925|PMID:14961764) MGI PMID:14961764 MGI:MGI:3041925 NCBI chrNW_004936471:30,213,742...30,312,873 JBrowse link
G Vps35 VPS35 retromer complex component ISO (PMID:25533483) ParkinsonsUK-UCL PMID:25533483 NCBI chrNW_004936475:50,476...77,797 JBrowse link
G Zfp36 ZFP36 ring finger protein ISO (MGI:MGI:5301204|PMID:21784977)
(MGI:MGI:2152007|PMID:11588035), (MGI:MGI:81466|PMID:8630730)
UniProtKB
MGI
PMID:8630730, PMID:11588035, PMID:21784977 MGI:MGI:2152007, MGI:MGI:5301204, MGI:MGI:81466 NCBI chrNW_004936661:2,251,148...2,253,527 JBrowse link
negative regulation of inflammatory response to antigenic stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2b Fc fragment of IgG receptor IIb ISO (MGI:MGI:3620376|PMID:16492738) MGI PMID:16492738 MGI:MGI:3620376 NCBI chrNW_004937131:80,014...96,114 JBrowse link
G Gpr17 G protein-coupled receptor 17 ISO (MGI:MGI:4819040|PMID:20574000) MGI PMID:20574000 MGI:MGI:4819040 NCBI chrNW_004936469:43,652,244...43,656,661 JBrowse link
G Gpx1 glutathione peroxidase 1 ISO (MGI:MGI:3608474|PMID:12751789) MGI PMID:12751789 MGI:MGI:3608474 NCBI chrNW_004936529:997,943...999,123 JBrowse link
G Gpx2 glutathione peroxidase 2 ISO (MGI:MGI:3608474|PMID:12751789) MGI PMID:12751789 MGI:MGI:3608474 NCBI chrNW_004936495:8,590,225...8,593,511 JBrowse link
G Il12b interleukin 12B ISO (MGI:MGI:3686795|PMID:16949315) MGI PMID:16949315 MGI:MGI:3686795 NCBI chrNW_004936515:4,056,214...4,066,121 JBrowse link
G Nlrp6 NLR family pyrin domain containing 6 ISO (MGI:MGI:5432950|PMID:22763455) CACAO PMID:22763455 MGI:MGI:5432950 NCBI chrNW_004936888:145,642...151,716 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO (MGI:MGI:3686795|PMID:16949315) MGI PMID:16949315 MGI:MGI:3686795 NCBI chrNW_004936475:3,708,069...3,742,845 JBrowse link
G Psma1 proteasome 20S subunit alpha 1 ISO (MGI:MGI:4419084|PMID:12874245) UniProtKB PMID:12874245 MGI:MGI:4419084 NCBI chrNW_004936528:4,195,072...4,207,263 JBrowse link
G Psmb4 proteasome 20S subunit beta 4 ISO (MGI:MGI:4419084|PMID:12874245) UniProtKB PMID:12874245 MGI:MGI:4419084 NCBI chrNW_004936580:1,610,635...1,613,357 JBrowse link
negative regulation of inflammatory response to wounding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101968601 signal transducer CD24 ISO (MGI:MGI:5913663|PMID:19264983) UniProtKB PMID:19264983 MGI:MGI:5913663 NCBI chrNW_004936491:16,706,745...16,707,010 JBrowse link
G Mdk midkine ISO (MGI:MGI:3761216|PMID:17015789) UniProt PMID:17015789 MGI:MGI:3761216 NCBI chrNW_004936562:2,687,825...2,690,292 JBrowse link
negative regulation of innate immune response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 ISO (MGI:MGI:5490396|PMID:23609450) UniProtKB PMID:23609450 MGI:MGI:5490396 NCBI chrNW_004936511:4,322,198...4,326,562 JBrowse link
G Dhx58 DExH-box helicase 58 ISO (MGI:MGI:5318004|PMID:21525357)
(PMID:21525357)
UniProtKB PMID:21525357 MGI:MGI:5318004 NCBI chrNW_004936490:16,940,776...16,949,836 JBrowse link
G Drd2 dopamine receptor D2 ISO (MGI:MGI:5473736|PMID:23242137) CACAO PMID:23242137 MGI:MGI:5473736 NCBI chrNW_004936612:1,094,686...1,154,149 JBrowse link
G Grn granulin precursor ISO (MGI:MGI:4421471|PMID:20026663) UniProt PMID:20026663 MGI:MGI:4421471 NCBI chrNW_004936541:793,548...800,271 JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO (MGI:MGI:5437532|PMID:22842346) UniProtKB PMID:22842346 MGI:MGI:5437532 NCBI chrNW_004936515:6,001,324...6,015,407 JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 ISO (MGI:MGI:2183694|PMID:12150927) BHF-UCL PMID:12150927 MGI:MGI:2183694 NCBI chrNW_004936545:4,233,353...4,284,324 JBrowse link
G LOC101964209 C-C chemokine receptor type 1 ISO (MGI:MGI:4943412|PMID:15557190) BHF-UCL PMID:15557190 MGI:MGI:4943412 NCBI chrNW_004936596:177,774...183,186 JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 ISO (PMID:23399697) UniProtKB PMID:23399697 NCBI chrNW_004936474:6,479,640...6,486,080 JBrowse link
G Nlrc3 NLR family CARD domain containing 3 ISO (MGI:MGI:5568884|PMID:24560620) UniProtKB PMID:24560620 MGI:MGI:5568884 NCBI chrNW_004936694:757,121...773,924 JBrowse link
G Nlrx1 NLR family member X1 ISO (MGI:MGI:5050761|PMID:21703540) MGI PMID:21703540 MGI:MGI:5050761 NCBI chrNW_004936542:4,105,980...4,121,176 JBrowse link
G Nmi N-myc and STAT interactor ISO (MGI:MGI:5546557|PMID:23956435) MGI PMID:23956435 MGI:MGI:5546557 NCBI chrNW_004936469:26,194,237...26,215,244 JBrowse link
G Tnfaip3 TNF alpha induced protein 3 ISO (MGI:MGI:5490396|PMID:23609450) UniProtKB PMID:23609450 MGI:MGI:5490396 NCBI chrNW_004936560:5,124,955...5,138,988 JBrowse link
G Trafd1 TRAF-type zinc finger domain containing 1 ISO (MGI:MGI:3831253|PMID:18849341) UniProtKB PMID:18849341 MGI:MGI:3831253 NCBI chrNW_004936668:2,360,755...2,383,750 JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase ISO (MGI:MGI:3773763|PMID:18083102) UniProtKB PMID:18083102 MGI:MGI:3773763 NCBI chrNW_004936471:4,893,185...4,910,779 JBrowse link
negative regulation of interferon-gamma-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 ISO (PMID:11679576) UniProtKB PMID:11679576 NCBI chrNW_004936694:43,898...74,939 JBrowse link
G Otop1 otopetrin 1 ISO (MGI:MGI:5750846|PMID:24379350) UniProtKB PMID:24379350 MGI:MGI:5750846 NCBI chrNW_004936477:16,876,725...16,899,007 JBrowse link
G Parp14 poly(ADP-ribose) polymerase family member 14 ISO (PMID:27796300)
(MGI:MGI:5905929|PMID:27796300)
UniProtKB PMID:27796300 MGI:MGI:5905929 NCBI chrNW_004936536:8,923,398...8,976,583 JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO (PMID:21268089) BHF-UCL PMID:21268089 NCBI chrNW_004936602:1,230,907...1,368,588 JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 ISO (MGI:MGI:5493216|PMID:12138178) UniProtKB PMID:12138178 MGI:MGI:5493216 NCBI chrNW_004936626:2,390,004...2,472,039 JBrowse link
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein ISO (PMID:19164550) UniProtKB PMID:19164550 NCBI chrNW_004936677:2,371,400...2,376,608 JBrowse link
G Dhx58 DExH-box helicase 58 ISO (PMID:21187438) UniProtKB PMID:21187438 NCBI chrNW_004936490:16,940,776...16,949,836 JBrowse link
G Riok3 RIO kinase 3 ISO (PMID:25865883) UniProtKB PMID:25865883 NCBI chrNW_004936550:2,921,272...2,949,288 JBrowse link
G Tkfc triokinase and FMN cyclase ISO (PMID:17600090) UniProtKB PMID:17600090 NCBI chrNW_004936581:1,697,965...1,710,363 JBrowse link
negative regulation of microglial cell activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst7 cystatin F ISO (MGI:MGI:5904382|PMID:28251676) MGI PMID:28251676 MGI:MGI:5904382 NCBI chrNW_004936620:853,533...870,609 JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO PMID:19627440 ARUK-UCL PMID:19627440 RGD:13673772 NCBI chrNW_004936475:9,443,851...9,454,715 JBrowse link
G Grn granulin precursor ISO (MGI:MGI:5440302|PMID:23041626) UniProt PMID:23041626 MGI:MGI:5440302 NCBI chrNW_004936541:793,548...800,271 JBrowse link
G Ldlr low density lipoprotein receptor ISO (MGI:MGI:4415751|PMID:20005821) ARUK-UCL PMID:20005821 MGI:MGI:4415751 NCBI chrNW_004936659:1,259,405...1,300,545 JBrowse link
G Nr1d1 nuclear receptor subfamily 1 group D member 1 ISO (MGI:MGI:6283959|PMID:30792350) UniProt PMID:30792350 MGI:MGI:6283959 NCBI chrNW_004936490:15,206,194...15,213,858 JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO (MGI:MGI:6270781|PMID:30412727) ARUK-UCL PMID:30412727 MGI:MGI:6270781 NCBI chrNW_004936602:1,230,907...1,368,588 JBrowse link
G Syt11 synaptotagmin 11 ISO (MGI:MGI:5913303|PMID:28686317) UniProt PMID:28686317 MGI:MGI:5913303 NCBI chrNW_004936580:5,123,196...5,142,976 JBrowse link
G Tafa3 TAFA chemokine like family member 3 ISO (MGI:MGI:5621218|PMID:25595455) MGI PMID:25595455 MGI:MGI:5621218 NCBI chrNW_004936690:1,273,255...1,281,362 JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 molecule ISO (MGI:MGI:5569209|PMID:24658051) MGI PMID:24658051 MGI:MGI:5569209 NCBI chrNW_004936834:432,538...522,118 JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 ISO (MGI:MGI:5491117|PMID:23408620) UniProtKB PMID:23408620 MGI:MGI:5491117 NCBI chrNW_004936538:4,034,467...4,050,240 JBrowse link
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin beta 2 ISO (PMID:18604210) UniProtKB PMID:18604210 NCBI chrNW_004936677:3,173,054...3,181,475 JBrowse link
G Clec12b C-type lectin domain family 12 member B ISO (PMID:17562706) UniProtKB PMID:17562706 NCBI chrNW_004936902:520,825...528,181 JBrowse link
G Crk CRK proto-oncogene, adaptor protein ISO RGD PMID:18835194 RGD:11568650 NCBI chrNW_004936538:7,581,453...7,609,543 JBrowse link
G Gfer growth factor, augmenter of liver regeneration ISO RGD PMID:9021955 RGD:9685777 NCBI chrNW_004936694:2,051,362...2,053,812 JBrowse link
G Igf2 insulin like growth factor 2 ISO RGD PMID:9021955 RGD:9685777 NCBI chrNW_004936816:972,902...981,232 JBrowse link
G Lgals9 galectin 9 ISO (PMID:23408620) UniProtKB PMID:23408620 NCBI chrNW_004936538:4,034,467...4,050,240 JBrowse link
G Sh2d1b SH2 domain containing 1B ISO (MGI:MGI:3639618|PMID:16127454) MGI PMID:16127454 MGI:MGI:3639618 NCBI chrNW_004936831:604,308...635,459 JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 ISO (PMID:23696226)
(MGI:MGI:5512785|PMID:23696226)
UniProtKB PMID:23696226 MGI:MGI:5512785 NCBI chrNW_004936706:37,480...53,306 JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO (MGI:MGI:5437532|PMID:22842346) UniProtKB PMID:22842346 MGI:MGI:5437532 NCBI chrNW_004936515:6,001,324...6,015,407 JBrowse link
G LOC101976242 NKG2-D type II integral membrane protein ISO RGD PMID:12782717 RGD:1299590 NCBI chrNW_004936902:216,495...229,150 JBrowse link
negative regulation of neuroinflammatory response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd200 CD200 molecule ISO (MGI:MGI:1927692|PMID:11099416)
PMID:18164423
ARUK-UCL PMID:11099416, PMID:18164423 MGI:MGI:1927692, RGD:13792521 NCBI chrNW_004936536:8,337...33,954 JBrowse link
G Igf1 insulin like growth factor 1 ISO (PMID:27277332) ARUK-UCL PMID:27277332 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Nr1d1 nuclear receptor subfamily 1 group D member 1 ISO (MGI:MGI:6283959|PMID:30792350) UniProt PMID:30792350 MGI:MGI:6283959 NCBI chrNW_004936490:15,206,194...15,213,858 JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO (MGI:MGI:6270781|PMID:30412727) ARUK-UCL PMID:30412727 MGI:MGI:6270781 NCBI chrNW_004936602:1,230,907...1,368,588 JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO (MGI:MGI:5775216|PMID:27147664) ARUK-UCL PMID:27147664 MGI:MGI:5775216 NCBI chrNW_004936474:908,414...935,765 JBrowse link
negative regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp10 dual specificity phosphatase 10 ISO (MGI:MGI:4366202|PMID:19696743) MGI PMID:19696743 MGI:MGI:4366202 NCBI chrNW_004936650:679,650...718,867 JBrowse link
G Grn granulin precursor ISO (PMID:12526812) UniProt PMID:12526812 NCBI chrNW_004936541:793,548...800,271 JBrowse link
G Ins insulin ISO (PMID:11443198) BHF-UCL PMID:11443198 NCBI chrNW_004936816:1,002,137...1,003,357 JBrowse link
G Rps19 ribosomal protein S19 ISO (PMID:15750715) UniProtKB PMID:15750715 NCBI chrNW_004936706:568,443...575,973 JBrowse link
G Slamf8 SLAM family member 8 ISO (MGI:MGI:5752697|PMID:25799045) MGI PMID:25799045 MGI:MGI:5752697 NCBI chrNW_004936740:776,557...786,182 JBrowse link
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein ISO (PMID:19164550) UniProtKB PMID:19164550 NCBI chrNW_004936677:2,371,400...2,376,608 JBrowse link
G Dhx58 DExH-box helicase 58 ISO (MGI:MGI:3836702|PMID:17475874)
(PMID:21187438)
(PMID:18411269)
UniProtKB PMID:17475874, PMID:18411269, PMID:21187438 MGI:MGI:3836702 NCBI chrNW_004936490:16,940,776...16,949,836 JBrowse link
G Gpatch3 G-patch domain containing 3 ISO (PMID:28414768) UniProtKB PMID:28414768 NCBI chrNW_004936474:11,298,802...11,310,609 JBrowse link
G Nlrx1 NLR family member X1 ISO (MGI:MGI:5050761|PMID:21703540) MGI PMID:21703540 MGI:MGI:5050761 NCBI chrNW_004936542:4,105,980...4,121,176 JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor ISO (PMID:26471729) UniProtKB PMID:26471729 NCBI chrNW_004936594:5,206,222...5,251,042 JBrowse link
G Rnf125 ring finger protein 125 ISO (PMID:17460044), (PMID:26471729) UniProtKB PMID:17460044, PMID:26471729 NCBI chrNW_004936682:1,228,903...1,268,651 JBrowse link
G Sec14l1 SEC14 like lipid binding 1 ISO (PMID:23843640) UniProtKB PMID:23843640 NCBI chrNW_004936594:2,048,146...2,100,808 JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 ISO (PMID:26471729) UniProtKB PMID:26471729 NCBI chrNW_004936619:3,395,130...3,419,704 JBrowse link
negative regulation of type I hypersensitivity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2b Fc fragment of IgG receptor IIb ISO (MGI:MGI:78617|PMID:8552190) MGI PMID:8552190 MGI:MGI:78617 NCBI chrNW_004937131:80,014...96,114 JBrowse link
negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase RNA specific ISO (MGI:MGI:3821394|PMID:19060901) MGI PMID:19060901 MGI:MGI:3821394 NCBI chrNW_004936580:4,183,016...4,208,341 JBrowse link
G Cactin cactin, spliceosome C complex subunit ISO (PMID:20829348) UniProtKB PMID:20829348 NCBI chrNW_004936588:2,051,636...2,061,651 JBrowse link
G Cnot7 CCR4-NOT transcription complex subunit 7 ISO (PMID:23386060) UniProtKB PMID:23386060 NCBI chrNW_004936573:6,288,397...6,305,984 JBrowse link
G Dcst1 DC-STAMP domain containing 1 ISO (PMID:27782195) UniProtKB PMID:27782195 NCBI chrNW_004936580:4,571,349...4,586,459 JBrowse link
G Mettl3 methyltransferase like 3 ISO (PMID:30559377) UniProt PMID:30559377 NCBI chrNW_004936880:646,835...661,312 JBrowse link
G Mmp12 matrix metallopeptidase 12 ISO (MGI:MGI:5583923|PMID:24784232) CAFA PMID:24784232 MGI:MGI:5583923 NCBI chrNW_004936551:5,107,567...5,117,843 JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 ISO (PMID:23399697) UniProtKB PMID:23399697 NCBI chrNW_004936474:6,479,640...6,486,080 JBrowse link
G Nlrc5 NLR family CARD domain containing 5 ISO (PMID:20434986)
(MGI:MGI:4454346|PMID:20434986)
UniProtKB PMID:20434986 MGI:MGI:4454346 NCBI chrNW_004936475:9,137,929...9,218,682 JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 ISO (PMID:11909529)
(MGI:MGI:3691503|PMID:11909529), (MGI:MGI:5493216|PMID:12138178)
UniProtKB PMID:11909529, PMID:12138178 MGI:MGI:3691503, MGI:MGI:5493216 NCBI chrNW_004936626:2,390,004...2,472,039 JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 ISO (PMID:29670289)
(MGI:MGI:5521417|PMID:23972988)
UniProtKB PMID:23972988, PMID:29670289 MGI:MGI:5521417 NCBI chrNW_004936561:4,180,607...4,238,623 JBrowse link
G Trex1 three prime repair exonuclease 1 ISO (MGI:MGI:3834787|PMID:18724932) MGI PMID:18724932 MGI:MGI:3834787 NCBI chrNW_004936529:264,535...266,451 JBrowse link
G Ttll12 tubulin tyrosine ligase like 12 ISO (PMID:28011935) UniProt PMID:28011935 NCBI chrNW_004936718:996,758...1,013,372 JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein 2 ISO (PMID:30559377) UniProt PMID:30559377 NCBI chrNW_004936474:12,791,121...12,827,122 JBrowse link
G Ythdf3 YTH N6-methyladenosine RNA binding protein 3 ISO (MGI:MGI:6316470|PMID:30591559) UniProt PMID:30591559 MGI:MGI:6316470 NCBI chrNW_004936496:10,323,338...10,362,150 JBrowse link
negative regulation of type IV hypersensitivity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spn sialophorin ISO (MGI:MGI:3029937|PMID:9645617) MGI PMID:9645617 MGI:MGI:3029937 NCBI chrNW_004936501:12,773,967...12,776,642 JBrowse link
negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tspan6 tetraspanin 6 ISO (PMID:22908223) UniProtKB PMID:22908223 NCBI chrNW_004936584:5,842,549...5,848,533 JBrowse link
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tap1 transporter 1, ATP binding cassette subfamily B member ISO RGD PMID:8120379 RGD:2312378 NCBI chrNW_004936476:25,899,514...25,907,690 JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:8120379 RGD:2312378 NCBI chrNW_004936476:25,913,699...25,923,419 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11968
    negative regulation of biological process 4659
      negative regulation of response to stimulus 1497
        negative regulation of defense response 210
          negative regulation of CRISPR-cas system 0
          negative regulation of antifungal peptide production + 0
          negative regulation of behavioral fear response 1
          negative regulation of cellular defense response 0
          negative regulation of defense response to bacterium + 5
          negative regulation of defense response to insect 0
          negative regulation of defense response to oomycetes 0
          negative regulation of defense response to virus + 24
          negative regulation of inflammatory response + 144
          negative regulation of innate immune response + 54
          negative regulation of neutrophil mediated killing of symbiont cell + 0
          negative regulation of xenophagy 0
          suppression of host defenses by symbiont + 0
Path 2
Term Annotations click to browse term
  biological_process 11968
    biological regulation 8764
      regulation of biological process 8316
        regulation of response to stimulus 3309
          regulation of response to stress 1232
            regulation of defense response 530
              negative regulation of defense response 210
                negative regulation of CRISPR-cas system 0
                negative regulation of antifungal peptide production + 0
                negative regulation of behavioral fear response 1
                negative regulation of cellular defense response 0
                negative regulation of defense response to bacterium + 5
                negative regulation of defense response to insect 0
                negative regulation of defense response to oomycetes 0
                negative regulation of defense response to virus + 24
                negative regulation of inflammatory response + 144
                negative regulation of innate immune response + 54
                negative regulation of neutrophil mediated killing of symbiont cell + 0
                negative regulation of xenophagy 0
                suppression of host defenses by symbiont + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.