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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of heterochromatin assembly
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Accession:GO:0031453 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of heterochromatin formation.
Synonyms:exact_synonym: positive regulation of heterochromatin formation;   up regulation of heterochromatin formation;   upregulation of heterochromatin formation
 narrow_synonym: activation of heterochromatin formation;   stimulation of heterochromatin formation


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positive regulation of heterochromatin assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpr translocated promoter region, nuclear basket protein ISO (PMID:20407419) UniProtKB PMID:20407419 NCBI chrNW_004936481:4,050,693...4,111,682 JBrowse link
positive regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf7ip activating transcription factor 7 interacting protein ISO (PMID:27732843) UniProt PMID:27732843 NCBI chrNW_004936587:2,922,855...3,026,773 JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO (PMID:24623306) UniProtKB PMID:24623306 NCBI chrNW_004936659:520,181...565,496 JBrowse link
G Morc2 MORC family CW-type zinc finger 2 ISO (PMID:28581500), (PMID:29211708)
(MGI:MGI:6271895|PMID:29728365)
UniProt PMID:28581500, PMID:29211708, PMID:29728365 MGI:MGI:6271895 NCBI chrNW_004936755:133,315...171,507 JBrowse link
G Mphosph8 M-phase phosphoprotein 8 ISO (PMID:28581500), (PMID:29211708) UniProt PMID:28581500, PMID:29211708 NCBI chrNW_004936720:1,972,063...2,025,283 JBrowse link
G Pphln1 periphilin 1 ISO (PMID:28581500) UniProt PMID:28581500 NCBI chrNW_004936512:1,001,733...1,158,647 JBrowse link
G Resf1 retroelement silencing factor 1 ISO (MGI:MGI:6271895|PMID:29728365) UniProt PMID:29728365 MGI:MGI:6271895 NCBI chrNW_004936607:4,247,824...4,274,410 JBrowse link
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 ISO (MGI:MGI:5440670|PMID:20164836), (MGI:MGI:6271895|PMID:29728365)
(PMID:24623306), (PMID:27732843)
UniProt PMID:20164836, PMID:24623306, PMID:27732843, PMID:29728365 MGI:MGI:5440670, MGI:MGI:6271895 NCBI chrNW_004936580:1,146,286...1,192,842 JBrowse link
G Tasor transcription activation suppressor ISO (PMID:28581500), (PMID:29211708) UniProt PMID:28581500, PMID:29211708 NCBI chrNW_004936473:7,053,797...7,098,608 JBrowse link
G Trim28 tripartite motif containing 28 ISO (PMID:24623306)
(MGI:MGI:5440670|PMID:20164836)
UniProtKB
UniProt
PMID:20164836, PMID:24623306 MGI:MGI:5440670 NCBI chrNW_004937062:126,832...132,938 JBrowse link
G Znf304 zinc finger protein 304 ISO (PMID:24623306) UniProtKB PMID:24623306 NCBI chrNW_004936897:244,051...253,580 JBrowse link
positive regulation of subtelomeric heterochromatin assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt6 sirtuin 6 ISO (PMID:21847107) BHF-UCL PMID:21847107 NCBI chrNW_004936588:2,387,162...2,394,066 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11968
    cellular process 11136
      positive regulation of cellular process 5031
        positive regulation of cellular component biogenesis 530
          positive regulation of heterochromatin assembly 12
            positive regulation of DNA methylation-dependent heterochromatin assembly 10
            positive regulation of extent of heterochromatin assembly 0
            positive regulation of pericentric heterochromatin assembly 0
            positive regulation of rDNA heterochromatin assembly 0
            positive regulation of silent mating-type cassette heterochromatin assembly 0
            positive regulation of subtelomeric heterochromatin assembly 1
Path 2
Term Annotations click to browse term
  biological_process 11968
    metabolic process 7653
      cellular metabolic process 7051
        cellular aromatic compound metabolic process 3743
          nucleobase-containing compound metabolic process 3574
            nucleic acid metabolic process 3288
              RNA metabolic process 2915
                regulation of RNA metabolic process 2500
                  negative regulation of RNA metabolic process 1159
                    negative regulation of RNA biosynthetic process 1068
                      negative regulation of nucleic acid-templated transcription 1066
                        negative regulation of transcription, DNA-templated 1062
                          chromatin organization involved in negative regulation of transcription 59
                            heterochromatin assembly 41
                              regulation of heterochromatin assembly 18
                                positive regulation of heterochromatin assembly 12
                                  positive regulation of DNA methylation-dependent heterochromatin assembly 10
                                  positive regulation of extent of heterochromatin assembly 0
                                  positive regulation of pericentric heterochromatin assembly 0
                                  positive regulation of rDNA heterochromatin assembly 0
                                  positive regulation of silent mating-type cassette heterochromatin assembly 0
                                  positive regulation of subtelomeric heterochromatin assembly 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.