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ONTOLOGY REPORT - ANNOTATIONS


Term:TRAMP complex
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Accession:GO:0031499 term browser browse the term
Definition:A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.
Synonyms:narrow_synonym: TRAMP4 complex;   TRAMP5 complex;   Trf4 complex;   Trf4 poly(A) polymerase complex;   Trf4p-Air2p-Mtr4p polyadenylation complex
 xref: Wikipedia:TRAMP_complex


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TRAMP complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mtrex Mtr4 exosome RNA helicase JBrowse link 2 44,726,716 44,787,013 RGD:1624291
G Tent4a terminal nucleotidyltransferase 4A JBrowse link 1 36,400,056 36,433,238 RGD:13792537
G Tent4b terminal nucleotidyltransferase 4B JBrowse link 19 19,771,289 19,834,759 RGD:1624291
RGD:13792537
G Zcchc8 zinc finger CCHC-type containing 8 JBrowse link 12 38,303,665 38,327,174 RGD:1624291

Term paths to the root
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Term Annotations click to browse term
  cellular_component 19949
    protein-containing complex 5829
      TRAMP complex 4
Path 2
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  cellular_component 19949
    cellular anatomical entity 19598
      organelle 12670
        membrane-bounded organelle 10978
          intracellular membrane-bounded organelle 10066
            nucleus 6843
              TRAMP complex 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.