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ONTOLOGY REPORT - ANNOTATIONS


Term:G2 DNA damage checkpoint
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Accession:GO:0031572 term browser browse the term
Definition:A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase in the cell cycle in response to DNA damage.
Comment:Note that this term should only be used as a grouping term for the mitotic and meiotic G2 DNA damage checkpoints, and should not be used for direct manual annotation. You should always be able to choose one of its child terms instead.
Synonyms:exact_synonym: G2/M transition DNA damage checkpoint


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mitotic G2 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07049960.1 RGD:13792537
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
G Brsk1 BR serine/threonine kinase 1 JBrowse link 1 72,701,281 72,727,061 RGD:1624291
G Brsk2 BR serine/threonine kinase 2 JBrowse link 1 214,918,757 214,940,883 RGD:8554801
G Ccng1 cyclin G1 JBrowse link 10 25,903,925 25,910,298 RGD:2316029
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:1624291
RGD:13792537
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 JBrowse link 10 84,780,644 84,789,800 RGD:1600115
RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1624291
G Clspn claspin JBrowse link 5 144,577,670 144,617,507 RGD:1624291
RGD:13792537
G Donson DNA replication fork stabilization factor DONSON JBrowse link 11 31,834,608 31,847,751 RGD:1624291
G Foxn3 forkhead box N3 JBrowse link 6 123,183,720 123,577,719 RGD:1624291
G Foxo4 forkhead box O4 JBrowse link X 71,155,284 71,162,158 RGD:1624291
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:1624291
RGD:1600115
G Ier3 immediate early response 3 JBrowse link 20 3,438,798 3,440,002 RGD:1624291
G LOC100302465 hypothetical LOC100302465 JBrowse link 1 206,324,763 206,417,143 RGD:1624291
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase JBrowse link 4 147,744,673 147,756,462 RGD:1624291
G Mre11 MRE11 homolog, double strand break repair nuclease JBrowse link 8 13,304,355 13,350,329 RGD:1624291
RGD:13792537
RGD:1600115
G Mrnip MRN complex interacting protein JBrowse link 10 35,680,687 35,704,685 RGD:1624291
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1624291
RGD:13792537
RGD:1600115
G Nop53 NOP53 ribosome biogenesis factor JBrowse link 1 77,836,522 77,843,991 RGD:1624291
G Syf2 SYF2 pre-mRNA-splicing factor JBrowse link 5 153,269,638 153,277,562 RGD:1624291
G Taok1 TAO kinase 1 JBrowse link 10 62,542,870 62,630,341 RGD:1600115
RGD:1624291
G Taok2 TAO kinase 2 JBrowse link 1 198,301,789 198,354,601 RGD:1600115
RGD:1624291
G Taok3 TAO kinase 3 JBrowse link 12 45,037,951 45,116,593 RGD:1600115
RGD:1624291
G Ticrr TOPBP1-interacting checkpoint and replication regulator JBrowse link 1 141,391,738 141,433,615 RGD:13792537
G Topbp1 DNA topoisomerase II binding protein 1 JBrowse link 8 111,790,655 111,835,224 RGD:13792537
G Trim39 tripartite motif-containing 39 JBrowse link 20 2,500,691 2,514,546 RGD:1600115
RGD:1624291
regulation of signal transduction involved in mitotic G2 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rint1 RAD50 interactor 1 JBrowse link 4 7,851,602 7,885,446 RGD:1624291
RGD:13792537
signal transduction involved in G2 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abraxas1 abraxas 1, BRCA1 A complex subunit JBrowse link 14 10,424,674 10,439,010 RGD:1600115
RGD:1624291
G Babam1 BRISC and BRCA1 A complex member 1 JBrowse link 16 19,792,720 19,798,886 RGD:1600115
RGD:1624291
G Babam2 BRISC and BRCA1 A complex member 2 JBrowse link 6 25,666,654 26,135,888 RGD:1624291
RGD:1600115
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:1600115
RGD:1624291
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 JBrowse link 9 9,863,380 9,865,920 RGD:1600115
RGD:1624291
G Cdc14b cell division cycle 14B JBrowse link 17 1,709,703 1,797,732 RGD:1624291
G Chek1 checkpoint kinase 1 JBrowse link 8 39,181,162 39,201,588 RGD:1624291
G Dtl denticleless E3 ubiquitin protein ligase homolog JBrowse link 13 110,219,276 110,257,345 RGD:1624291
G Fzr1 fizzy and cell division cycle 20 related 1 JBrowse link 7 11,201,690 11,213,614 RGD:1624291
G Plk1 polo-like kinase 1 JBrowse link 1 192,115,990 192,125,969 RGD:1600115
RGD:1624291
G Uimc1 ubiquitin interaction motif containing 1 JBrowse link 17 10,061,915 10,130,921 RGD:1600115
RGD:1624291
signal transduction involved in mitotic G2 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      cell cycle checkpoint 188
        DNA integrity checkpoint 126
          DNA damage checkpoint 116
            G2 DNA damage checkpoint 40
              detection of DNA damage stimulus involved in G2 DNA damage checkpoint + 0
              mitotic G2 DNA damage checkpoint + 29
              signal transduction involved in G2 DNA damage checkpoint + 13
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          negative regulation of cellular process 5079
            negative regulation of cell cycle 461
              cell cycle checkpoint 188
                DNA integrity checkpoint 126
                  DNA damage checkpoint 116
                    G2 DNA damage checkpoint 40
                      detection of DNA damage stimulus involved in G2 DNA damage checkpoint + 0
                      mitotic G2 DNA damage checkpoint + 29
                      signal transduction involved in G2 DNA damage checkpoint + 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.