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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
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Accession:GO:0031587 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.
Synonyms:exact_synonym: positive regulation of IP3 receptor activity;   positive regulation of inositol-1,4,5-trisphosphate receptor activity;   up regulation of IP3 receptor activity;   upregulation of IP3 receptor activity
 narrow_synonym: activation of IP3 receptor activity;   stimulation of IP3 receptor activity


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positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hap1 huntingtin-associated protein 1 JBrowse link 10 88,257,975 88,266,210 RGD:6482800
RGD:1600115
RGD:1624291
G Htt huntingtin JBrowse link 14 81,105,139 81,254,637 RGD:1600115
RGD:1624291
G P2ry6 pyrimidinergic receptor P2Y6 JBrowse link 1 165,972,439 166,008,348 RGD:13673830
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18008
    cellular process 16139
      positive regulation of cellular process 5493
        positive regulation of calcium ion transport into cytosol 67
          positive regulation of release of sequestered calcium ion into cytosol 46
            positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 4
Path 2
Term Annotations click to browse term
  biological_process 18008
    biological regulation 12699
      regulation of biological quality 4158
        homeostatic process 1988
          chemical homeostasis 1281
            ion homeostasis 858
              cellular ion homeostasis 706
                cellular cation homeostasis 693
                  cellular metal ion homeostasis 633
                    cellular calcium ion homeostasis 521
                      regulation of cytosolic calcium ion concentration 424
                        positive regulation of cytosolic calcium ion concentration 368
                          calcium ion transport into cytosol 184
                            calcium ion transmembrane import into cytosol 160
                              release of sequestered calcium ion into cytosol 140
                                regulation of release of sequestered calcium ion into cytosol 87
                                  regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 6
                                    positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.