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ONTOLOGY REPORT - ANNOTATIONS


Term:protection from non-homologous end joining at telomere
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Accession:GO:0031848 term browser browse the term
Definition:A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse.
Synonyms:exact_synonym: protection from NHEJ-mediated telomere fusion


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protection from non-homologous end joining at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor ISO (MGI:MGI:3829120|PMID:18185984) RGD PMID:18185984 MGI:MGI:3829120 NCBI chr19:37,665,289...37,668,043
Ensembl chr19:37,665,296...37,667,987
JBrowse link
G Dclre1a DNA cross-link repair 1A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:277,335,792...277,355,701
Ensembl chr 1:277,335,790...277,355,075
JBrowse link
G Dclre1b DNA cross-link repair 1B IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(MGI:MGI:4462732|PMID:20551906), (MGI:MGI:4830207|PMID:20619712)
(PMID:16730175), (PMID:20479256)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:16730175, PMID:20479256, PMID:20551906, PMID:20619712, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4462732, MGI:MGI:4830207, RGD:13792537 NCBI chr 2:206,285,085...206,293,599
Ensembl chr 2:206,285,089...206,293,599
JBrowse link
G Dclre1c DNA cross-link repair 1C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:78,782,512...78,812,140
Ensembl chr17:78,783,437...78,812,111
JBrowse link
G Pot1b protection of telomeres 1B IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 9:7,845,697...7,902,270
Ensembl chr 9:7,845,845...7,891,514
JBrowse link
G Terf2 telomeric repeat binding factor 2 ISO
IBA
ComplexPortal:CPX-1993 (PMID:14690602), (PMID:17499040), (PMID:24095731)
PMID:21873635
MGI:MGI:3619525 (MGI:MGI:3615734|PMID:15968270), (MGI:MGI:4830207|PMID:20619712), (MGI:MGI:5883205|PMID:24120135)
RGD PMID:14690602, PMID:15968270, PMID:17499040, PMID:20619712, PMID:24095731, PMID:24120135, PMID:21873635 MGI:MGI:3615734, MGI:MGI:4830207, MGI:MGI:5883205, RGD:13792537 NCBI chr19:39,271,992...39,301,506
Ensembl chr19:39,272,499...39,300,893
JBrowse link
G Terf2ip TERF2 interacting protein NOT ISS
ISO
GO_REF:0000024
(MGI:MGI:4440768|PMID:20339076), (MGI:MGI:4839412|PMID:20622869)
UniProt
RGD
PMID:20339076, PMID:20622869 GO_REF:0000024, MGI:MGI:4440768, MGI:MGI:4839412 NCBI chr19:44,231,317...44,238,406
Ensembl chr19:44,231,251...44,238,404
JBrowse link
negative regulation of protection from non-homologous end joining at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO (PMID:14690602) RGD PMID:14690602 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit ISO (PMID:14690602) RGD PMID:14690602 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 ISO (MGI:MGI:3758502|PMID:14690602) RGD PMID:14690602 MGI:MGI:3758502 NCBI chr 1:81,412,635...81,441,680
Ensembl chr 1:81,413,353...81,441,678
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 ISO (MGI:MGI:3758502|PMID:14690602) RGD PMID:14690602 MGI:MGI:3758502 NCBI chr 2:18,674,496...18,927,463
Ensembl chr 2:18,677,220...18,927,365
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    response to stimulus 10583
      response to stress 4063
        cellular response to stress 1981
          cellular response to DNA damage stimulus 786
            telomere maintenance in response to DNA damage 14
              protection from non-homologous end joining at telomere 11
                negative regulation of protection from non-homologous end joining at telomere 4
                positive regulation of protection from non-homologous end joining at telomere 0
                regulation of protection from non-homologous end joining at telomere + 4
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      organic substance metabolic process 11651
        organic cyclic compound metabolic process 5940
          nucleobase-containing compound metabolic process 5489
            nucleic acid metabolic process 4985
              DNA metabolic process 923
                telomere maintenance 127
                  telomere maintenance in response to DNA damage 14
                    protection from non-homologous end joining at telomere 11
                      negative regulation of protection from non-homologous end joining at telomere 4
                      positive regulation of protection from non-homologous end joining at telomere 0
                      regulation of protection from non-homologous end joining at telomere + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.