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ONTOLOGY REPORT - ANNOTATIONS


Term:TORC2 complex
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Accession:GO:0031932 term browser browse the term
Definition:A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p.
Synonyms:exact_synonym: TOR complex 2;   TORC 2 complex;   TORC2;   rapamycin and nutrient-insensitive TOR complex
 narrow_synonym: mTORC2
 xref: Wikipedia:MTORC1


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TORC2 complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07051501.1 RGD:13792537
G Mapkap1 MAPK associated protein 1 JBrowse link 3 13,484,952 13,701,772 RGD:1624291
RGD:13792537
G Mlst8 MTOR associated protein, LST8 homolog JBrowse link 10 13,839,250 13,845,001 RGD:1624291
RGD:13792537
RGD:1600115
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:1624291
RGD:13792537
G Prr5 proline rich 5 JBrowse link 7 125,569,791 125,609,340 RGD:1600115
RGD:13792537
RGD:1624291
G Prr5l proline rich 5 like JBrowse link 3 91,290,207 91,461,208 RGD:1600115
RGD:13792537
RGD:1624291
G Rictor RPTOR independent companion of MTOR, complex 2 JBrowse link 2 56,013,898 56,105,818 RGD:1624291
RGD:13792537
G Sesn1 sestrin 1 JBrowse link 20 46,667,116 46,758,306 RGD:13792537
G Sesn2 sestrin 2 JBrowse link 5 150,684,891 150,703,846 RGD:1624291
RGD:13792537
G Sesn3 sestrin 3 JBrowse link 8 12,823,060 12,878,749 RGD:1624291
RGD:13792537
G Telo2 telomere maintenance 2 JBrowse link 10 14,461,581 14,476,812 RGD:1624291
RGD:13792537
G Tti1 TELO2 interacting protein 1 JBrowse link 3 154,463,108 154,506,955 RGD:1624291
RGD:13792537

Term paths to the root
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  cellular_component 19951
    protein-containing complex 5828
      TOR complex 15
        TORC2 complex 12
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.