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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of TOR signaling
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Accession:GO:0032006 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of TOR signaling.
Synonyms:exact_synonym: regulation of TOR signaling pathway;   regulation of TOR signalling pathway;   regulation of target of rapamycin signaling pathway;   regulation of target of rapamycin signalling pathway
 related_synonym: regulation of TOR signaling cascade


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regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARAF A-Raf proto-oncogene, serine/threonine kinase JBrowse link X 39,997,026 40,007,783 RGD:9068941
G FAM83D family with sequence similarity 83 member D JBrowse link 20 35,251,338 35,278,057 RGD:9068941
G FBXO9 F-box protein 9 JBrowse link 6 52,621,036 52,652,980 RGD:9068941
G FLCN folliculin JBrowse link 17 34,057,127 34,081,637 RGD:9068941
G GNA12 G protein subunit alpha 12 JBrowse link 7 2,989,832 3,104,848 RGD:9068941
G GPAT3 glycerol-3-phosphate acyltransferase 3 JBrowse link 4 40,590,801 40,660,527 RGD:9068941
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link 6 51,166,516 51,635,057 RGD:9068941
G RHEB Ras homolog, mTORC1 binding JBrowse link 7 143,054,747 143,108,011 RGD:9068941
G ROS1 ROS proto-oncogene 1, receptor tyrosine kinase JBrowse link 6 115,095,753 115,234,525 RGD:9068941
G RRAGB Ras related GTP binding B JBrowse link X 48,003,566 48,042,285 RGD:9068941
G RRAGC Ras related GTP binding C JBrowse link 1 38,110,578 38,132,179 RGD:9068941
G SLC7A1 solute carrier family 7 member 1 JBrowse link 13 10,791,600 10,877,082 RGD:9068941
G SLC7A3 solute carrier family 7 member 3 JBrowse link X 60,193,997 60,199,564 RGD:9068941
G TBCK TBC1 domain containing kinase JBrowse link 4 98,515,422 98,797,701 RGD:9068941
G TELO2 telomere maintenance 2 JBrowse link 16 112,856 130,175 RGD:9068941
G TMEM127 transmembrane protein 127 JBrowse link 2A 103,049,655 103,065,116 RGD:9068941
G TREM2 triggering receptor expressed on myeloid cells 2 JBrowse link 6 40,735,483 40,740,208 RGD:9068941
G TTI1 TELO2 interacting protein 1 JBrowse link 20 34,304,137 34,354,615 RGD:9068941
G ZMPSTE24 zinc metallopeptidase STE24 JBrowse link 1 39,545,264 39,589,721 RGD:9068941
negative regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1S1 AKT1 substrate 1 JBrowse link 19 46,882,073 46,890,404 RGD:9068941
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 11 13,436,580 13,547,135 RGD:9068941
G CRYBA1 crystallin beta A1 JBrowse link 17 27,522,647 27,530,767 RGD:9068941
G DDIT4 DNA damage inducible transcript 4 JBrowse link 10 68,796,712 68,798,840 RGD:9068941
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 22 12,774,147 12,929,261 RGD:9068941
G DEPTOR DEP domain containing MTOR interacting protein JBrowse link 8 116,563,935 116,743,843 RGD:9068941
G EPM2A EPM2A glucan phosphatase, laforin JBrowse link 6 143,179,097 143,525,223 RGD:9068941
G FLCN folliculin JBrowse link 17 34,057,127 34,081,637 RGD:9068941
G FNIP1 folliculin interacting protein 1 JBrowse link 5 127,070,906 127,219,548 RGD:9068941
G GSK3A glycogen synthase kinase 3 alpha JBrowse link 19 39,118,330 39,130,768 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 116,943,205 117,215,001 RGD:9068941
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 14 42,295,691 42,348,478 RGD:9068941
G MAPKAPK5 MAPK activated protein kinase 5 JBrowse link 12 109,416,610 109,471,729 RGD:9068941
G MINAR1 membrane integral NOTCH2 associated receptor 1 JBrowse link 15 58,402,688 58,445,461 RGD:9068941
G MTM1 myotubularin 1 JBrowse link X 140,218,742 140,323,495 RGD:9068941
G NPRL2 NPR2 like, GATOR1 complex subunit JBrowse link 3 50,273,611 50,277,175 RGD:9068941
G NPRL3 NPR3 like, GATOR1 complex subunit RGD:9068941
G PDCD6 programmed cell death 6 JBrowse link 5 250,025 291,055 RGD:9068941
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 5 69,581,748 69,620,721 RGD:9068941
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 1 55,928,577 55,998,628 RGD:9068941
G SH3BP4 SH3 domain binding protein 4 JBrowse link 2B 122,179,431 122,284,430 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 10 64,368,878 64,401,684 RGD:9068941
G TBC1D7 TBC1 domain family member 7 JBrowse link 6 13,150,677 13,174,661 RGD:9068941
G TMEM127 transmembrane protein 127 JBrowse link 2A 103,049,655 103,065,116 RGD:9068941
G TNFAIP8L1 TNF alpha induced protein 8 like 1 JBrowse link 19 3,658,205 3,674,237 RGD:9068941
G TSC1 TSC complex subunit 1 JBrowse link 9 104,007,708 104,060,938 RGD:9068941
G TSC2 TSC complex subunit 2 JBrowse link 16 615,776 655,411 RGD:9068941
G UBR1 ubiquitin protein ligase E3 component n-recognin 1 JBrowse link 15 21,899,611 22,064,606 RGD:9068941
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 JBrowse link 6 42,150,409 42,282,486 RGD:9068941
negative regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATM ATM serine/threonine kinase JBrowse link 11 103,109,979 103,256,405 RGD:9068941
G BMT2 base methyltransferase of 25S rRNA 2 homolog JBrowse link 7 104,786,390 104,905,357 RGD:9068941
G C12H12orf66 chromosome 12 C12orf66 homolog JBrowse link 12 24,691,658 24,721,618 RGD:9068941
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 22 11,321,259 11,325,787 RGD:9068941
G CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 RGD:9068941
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 22 12,774,147 12,929,261 RGD:9068941
G ITFG2 integrin alpha FG-GAP repeat containing 2 JBrowse link 12 2,933,227 2,980,509 RGD:9068941
G KPTN kaptin, actin binding protein JBrowse link 19 44,467,344 44,478,150 RGD:9068941
G RNF152 ring finger protein 152 JBrowse link 18 55,180,955 55,264,164 RGD:9068941
G SESN1 sestrin 1 JBrowse link 6 106,789,911 106,896,382 RGD:9068941
G SESN2 sestrin 2 JBrowse link 1 27,518,248 27,541,264 RGD:9068941
G SESN3 sestrin 3 JBrowse link 11 90,184,571 90,249,825 RGD:9068941
G SPAAR small regulatory polypeptide of amino acid response JBrowse link 9 35,760,064 35,762,224 RGD:9068941
G STK11 serine/threonine kinase 11 RGD:9068941
G SZT2 SZT2 subunit of KICSTOR complex JBrowse link 1 42,691,292 42,754,046 RGD:9068941
G TSC2 TSC complex subunit 2 JBrowse link 16 615,776 655,411 RGD:9068941
positive regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT3 AKT serine/threonine kinase 3 JBrowse link 1 219,107,482 219,463,140 RGD:9068941
G FLCN folliculin JBrowse link 17 34,057,127 34,081,637 RGD:9068941
G FNIP1 folliculin interacting protein 1 JBrowse link 5 127,070,906 127,219,548 RGD:9068941
G GOLPH3 golgi phosphoprotein 3 JBrowse link 5 78,157,724 78,215,933 RGD:9068941
G HDAC3 histone deacetylase 3 JBrowse link 5 136,981,790 136,997,786 RGD:9068941
G HTR6 5-hydroxytryptamine receptor 6 JBrowse link 1 18,619,683 18,635,822 RGD:9068941
G KDR kinase insert domain receptor JBrowse link 4 68,813,894 68,861,018 RGD:9068941
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 JBrowse link 11 67,177,580 67,183,631 RGD:9068941
G LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 JBrowse link 1 131,396,937 131,400,695 RGD:9068941
G LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 JBrowse link 4 92,304,115 92,317,461 RGD:9068941
G LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 JBrowse link 7 92,183,617 92,188,967 RGD:9068941
G LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 1 113,050,671 113,057,368 RGD:9068941
G LARS1 leucyl-tRNA synthetase 1 JBrowse link 5 141,562,798 141,631,388 RGD:9068941
G LEP leptin JBrowse link 7 120,230,896 120,248,602 RGD:9068941
G LIN28A lin-28 homolog A JBrowse link 1 25,674,751 25,693,684 RGD:9068941
G MIOS meiosis regulator for oocyte development JBrowse link 7 8,291,307 8,346,822 RGD:9068941
G MLST8 MTOR associated protein, LST8 homolog JBrowse link 16 1,063,534 1,067,706 RGD:9068941
G RELN reelin JBrowse link 7 95,464,285 95,984,813 RGD:9068941
G RHEB Ras homolog, mTORC1 binding JBrowse link 7 143,054,747 143,108,011 RGD:9068941
G RICTOR RPTOR independent companion of MTOR complex 2 JBrowse link 5 71,299,215 71,435,290 RGD:9068941
G RPTOR regulatory associated protein of MTOR complex 1 JBrowse link 17 74,973,420 75,389,339 RGD:9068941
G RRAGB Ras related GTP binding B JBrowse link X 48,003,566 48,042,285 RGD:9068941
G SEC13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 3 10,237,101 10,257,694 RGD:9068941
G SEH1L SEH1 like nucleoporin JBrowse link 18 1,342,928 1,379,719 RGD:9068941
G SLC38A9 solute carrier family 38 member 9 JBrowse link 5 58,312,101 58,397,365 RGD:9068941
G SMCR8 SMCR8-C9orf72 complex subunit JBrowse link 17 32,858,205 32,871,132 RGD:9068941
G TREM2 triggering receptor expressed on myeloid cells 2 JBrowse link 6 40,735,483 40,740,208 RGD:9068941
G WDR24 WD repeat domain 24 RGD:9068941
G WDR59 WD repeat domain 59 JBrowse link 16 55,438,945 55,553,937 RGD:9068941
G XBP1 X-box binding protein 1 JBrowse link 22 9,863,479 9,869,491 RGD:9068941
positive regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLEC16A C-type lectin domain containing 16A JBrowse link 16 9,887,877 10,124,500 RGD:9068941
G GPR137B G protein-coupled receptor 137B JBrowse link 1 211,709,507 211,775,846 RGD:9068941
G KLHL22 kelch like family member 22 RGD:9068941
G LARS1 leucyl-tRNA synthetase 1 JBrowse link 5 141,562,798 141,631,388 RGD:9068941
G PIH1D1 PIH1 domain containing 1 JBrowse link 19 46,459,855 46,465,882 RGD:9068941
G PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 JBrowse link 14 1,332,403 1,336,157 RGD:9068941
G RRAGA Ras related GTP binding A JBrowse link 9 18,868,781 18,870,356 RGD:9068941
G RRAGB Ras related GTP binding B JBrowse link X 48,003,566 48,042,285 RGD:9068941
G RRAGD Ras related GTP binding D JBrowse link 6 87,237,442 87,285,579 RGD:9068941
G SEH1L SEH1 like nucleoporin JBrowse link 18 1,342,928 1,379,719 RGD:9068941
G SIK3 SIK family kinase 3 JBrowse link 11 111,680,884 111,932,424 RGD:9068941
G TELO2 telomere maintenance 2 JBrowse link 16 112,856 130,175 RGD:9068941
positive regulation of TORC2 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIK3 SIK family kinase 3 JBrowse link 11 111,680,884 111,932,424 RGD:9068941
G TELO2 telomere maintenance 2 JBrowse link 16 112,856 130,175 RGD:9068941
regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C9orf72 C9orf72-SMCR8 complex subunit JBrowse link 9 27,395,054 27,422,282 RGD:9068941
G DGKQ diacylglycerol kinase theta JBrowse link 4 1,075,133 1,090,081 RGD:9068941
G DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 JBrowse link 1 182,237,556 182,255,984 RGD:9068941
G RRAGC Ras related GTP binding C JBrowse link 1 38,110,578 38,132,179 RGD:9068941
G SMCR8 SMCR8-C9orf72 complex subunit JBrowse link 17 32,858,205 32,871,132 RGD:9068941
regulation of TORC2 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PIH1D1 PIH1 domain containing 1 JBrowse link 19 46,459,855 46,465,882 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12490
    signaling 4282
      signal transduction 3790
        intracellular signal transduction 2033
          regulation of intracellular signal transduction 1483
            regulation of TOR signaling 96
              negative regulation of TOR signaling + 43
              positive regulation of TOR signaling + 39
              regulation of TORC1 signaling + 33
              regulation of TORC2 signaling + 3
Path 2
Term Annotations click to browse term
  biological_process 12490
    biological regulation 9101
      regulation of biological process 8628
        regulation of cellular process 8158
          signal transduction 3790
            regulation of signal transduction 2587
              regulation of intracellular signal transduction 1483
                regulation of TOR signaling 96
                  negative regulation of TOR signaling + 43
                  positive regulation of TOR signaling + 39
                  regulation of TORC1 signaling + 33
                  regulation of TORC2 signaling + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.