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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of TOR signaling
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Accession:GO:0032006 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of TOR signaling.
Synonyms:exact_synonym: regulation of TOR signaling pathway;   regulation of TOR signalling pathway;   regulation of target of rapamycin signaling pathway;   regulation of target of rapamycin signalling pathway
 related_synonym: regulation of TOR signaling cascade


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regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARAF A-Raf proto-oncogene, serine/threonine kinase JBrowse link X 41,180,082 41,191,579 RGD:9068941
G DDIT4 DNA damage inducible transcript 4 JBrowse link 4 22,916,718 22,918,893 RGD:13508589
G FAM83D family with sequence similarity 83 member D JBrowse link 24 27,302,442 27,323,780 RGD:13508589
G FBXO9 F-box protein 9 JBrowse link 12 20,514,590 20,562,507 RGD:9068941
G FLCN folliculin JBrowse link 5 42,176,093 42,195,718 RGD:9068941
G GBA glucosylceramidase beta JBrowse link 7 42,317,704 42,322,285 RGD:13508589
G GNA12 G protein subunit alpha 12 JBrowse link 6 14,375,144 14,476,018 RGD:13508589
G GPAT3 glycerol-3-phosphate acyltransferase 3 JBrowse link 32 7,355,154 7,414,921 RGD:13508589
G ITFG2 integrin alpha FG-GAP repeat containing 2 JBrowse link 27 41,933,741 41,944,464 RGD:13508589
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link 12 19,280,866 19,744,669 RGD:13508589
G RHEB Ras homolog, mTORC1 binding JBrowse link 16 15,439,910 15,483,489 RGD:9068941
G ROS1 ROS proto-oncogene 1, receptor tyrosine kinase JBrowse link 1 57,555,278 57,677,541 RGD:13508589
G RRAGB Ras related GTP binding B JBrowse link X 47,323,427 47,361,551 RGD:9068941
G RRAGC Ras related GTP binding C JBrowse link 15 3,875,193 3,892,501 RGD:9068941
G SLC7A1 solute carrier family 7 member 1 JBrowse link 25 10,272,949 10,363,793 RGD:9068941
G SLC7A3 solute carrier family 7 member 3 JBrowse link X 55,282,474 55,289,513 RGD:9068941
G TBCK TBC1 domain containing kinase JBrowse link 32 26,839,133 27,062,629 RGD:9068941
G TELO2 telomere maintenance 2 JBrowse link 6 39,309,224 39,320,215 RGD:9068941
G TMEM127 transmembrane protein 127 JBrowse link 17 34,512,753 34,527,208 RGD:13508589
G TTI1 TELO2 interacting protein 1 JBrowse link 24 26,505,913 26,552,418 RGD:13508589
G ZMPSTE24 zinc metallopeptidase STE24 JBrowse link 15 2,669,546 2,708,480 RGD:13508589
negative regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1S1 AKT1 substrate 1 JBrowse link 1 106,686,349 106,694,854 RGD:13508589
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 21 36,254,235 36,323,915 RGD:13508589
G CRYBA1 crystallin beta A1 JBrowse link 9 43,372,507 43,378,561 RGD:9068941
G DDIT4 DNA damage inducible transcript 4 JBrowse link 4 22,916,718 22,918,893 RGD:13508589
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 26 24,629,369 24,754,728 RGD:13508589
G DEPTOR DEP domain containing MTOR interacting protein JBrowse link 13 18,859,526 18,993,464 RGD:13508589
G EPM2A EPM2A glucan phosphatase, laforin JBrowse link 1 36,835,775 36,977,653 RGD:9068941
G FLCN folliculin JBrowse link 5 42,176,093 42,195,718 RGD:9068941
G FNIP1 folliculin interacting protein 1 JBrowse link 11 19,979,294 20,134,341 RGD:13508589
G GSK3A glycogen synthase kinase 3 alpha JBrowse link 1 112,129,116 112,138,714 RGD:13508589
G GSK3B glycogen synthase kinase 3 beta JBrowse link 33 23,458,369 23,659,878 RGD:9068941
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 8 36,614,045 36,656,692 RGD:13508589
G MAPKAPK5 MAPK activated protein kinase 5 JBrowse link 26 9,380,551 9,420,564 RGD:13508589
G MINAR1 membrane integral NOTCH2 associated receptor 1 JBrowse link 3 57,735,935 57,770,369 RGD:13508589
G MTM1 myotubularin 1 JBrowse link X 118,820,644 118,917,166 RGD:13508589
G NPRL2 NPR2 like, GATOR1 complex subunit JBrowse link 20 39,005,699 39,009,183 RGD:13508589
G NPRL3 NPR3 like, GATOR1 complex subunit JBrowse link 6 40,351,757 40,394,599 RGD:13508589
G PDCD6 programmed cell death 6 JBrowse link 34 11,909,657 11,929,850 RGD:9068941
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 4 68,579,061 68,614,548 RGD:9068941
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 5 52,809,792 52,855,072 RGD:13508589
G SH3BP4 SH3 domain binding protein 4 JBrowse link 25 46,049,631 46,133,065 RGD:13508589
G SIRT1 sirtuin 1 JBrowse link 4 19,188,616 19,220,031 RGD:9068941
G TBC1D7 TBC1 domain family member 7 JBrowse link 35 12,765,953 12,789,393 RGD:13508589
G TMEM127 transmembrane protein 127 JBrowse link 17 34,512,753 34,527,208 RGD:13508589
G TNFAIP8L1 TNF alpha induced protein 8 like 1 JBrowse link 20 55,098,121 55,111,228 RGD:13508589
G TSC1 TSC complex subunit 1 JBrowse link 9 51,409,307 51,459,546 RGD:13508589
G TSC2 TSC complex subunit 2 JBrowse link 6 38,865,509 38,898,977 RGD:13508589
G UBR1 ubiquitin protein ligase E3 component n-recognin 1 JBrowse link 30 9,869,769 10,006,994 RGD:13508589
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 JBrowse link 12 11,167,286 11,296,817 RGD:13508589
negative regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATM ATM serine/threonine kinase JBrowse link 5 24,180,129 24,297,207 RGD:13508589
G BMT2 base methyltransferase of 25S rRNA 2 homolog JBrowse link 14 52,363,629 52,456,440 RGD:13508589
G C10H12orf66 chromosome 10 C12orf66 homolog JBrowse link 10 6,977,602 6,998,204 RGD:13508589
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 26 23,439,472 23,443,950 RGD:13508589
G CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 JBrowse link 6 5,565,723 5,602,799 RGD:13508589
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 26 24,629,369 24,754,728 RGD:9068941
G FNIP1 folliculin interacting protein 1 JBrowse link 11 19,979,294 20,134,341 RGD:13508589
G FNIP2 folliculin interacting protein 2 JBrowse link 15 55,871,782 55,962,676 RGD:13508589
G ITFG2 integrin alpha FG-GAP repeat containing 2 JBrowse link 27 41,933,741 41,944,464 RGD:13508589
G KPTN kaptin, actin binding protein JBrowse link 1 108,535,140 108,544,405 RGD:13508589
G LOC106559493 small regulatory polypeptide of amino acid response-like JBrowse link 11 52,424,607 52,427,288 RGD:9068941
G RNF152 ring finger protein 152 JBrowse link 1 14,914,508 15,001,843 RGD:13508589
G SESN1 sestrin 1 JBrowse link 12 65,958,995 66,057,369 RGD:13508589
G SESN2 sestrin 2 JBrowse link 2 72,151,464 72,168,861 RGD:13508589
G SESN3 sestrin 3 JBrowse link 21 5,827,957 5,899,540 RGD:13508589
G STK11 serine/threonine kinase 11 JBrowse link 20 57,558,966 57,579,163 RGD:13508589
G SZT2 SZT2 subunit of KICSTOR complex JBrowse link 15 16,729,068 16,780,549 RGD:9068941
G TSC2 TSC complex subunit 2 JBrowse link 6 38,865,509 38,898,977 RGD:9068941
positive regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT3 AKT serine/threonine kinase 3 JBrowse link 7 34,633,064 34,931,112 RGD:13508589
G FLCN folliculin JBrowse link 5 42,176,093 42,195,718 RGD:9068941
G FNIP1 folliculin interacting protein 1 JBrowse link 11 19,979,294 20,134,341 RGD:13508589
G GAS6 growth arrest specific 6 JBrowse link 22 60,975,196 61,005,869 RGD:9068941
G GOLPH3 golgi phosphoprotein 3 JBrowse link 4 75,302,580 75,324,086 RGD:9068941
G HDAC3 histone deacetylase 3 JBrowse link 2 36,583,283 36,598,121 RGD:13508589
G HTR6 5-hydroxytryptamine receptor 6 JBrowse link 2 79,022,790 79,033,975 RGD:9068941
G KDR kinase insert domain receptor JBrowse link 13 47,442,861 47,484,574 RGD:9068941
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 JBrowse link 21 25,981,170 25,986,942 RGD:13508589
G LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 JBrowse link 7 41,760,632 41,764,926 RGD:13508589
G LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 JBrowse link 32 21,820,853 21,834,443 RGD:13508589
G LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 JBrowse link 6 9,372,728 9,376,047 RGD:13508589
G LARS1 leucyl-tRNA synthetase 1 JBrowse link 2 40,544,031 40,619,268 RGD:9068941
G LEP leptin JBrowse link 14 8,115,396 8,130,946 RGD:13508589
G LIN28A lin-28 homolog A JBrowse link 2 73,613,069 73,628,211 RGD:13508589
G LOC102156380 ragulator complex protein LAMTOR5 pseudogene JBrowse link 9 53,420,574 53,421,161 RGD:9068941
G MIOS meiosis regulator for oocyte development JBrowse link 14 23,171,028 23,208,055 RGD:13508589
G MLST8 MTOR associated protein, LST8 homolog JBrowse link 6 38,759,713 38,765,556 RGD:13508589
G RELN reelin JBrowse link 18 16,275,822 16,773,875 RGD:13508589
G RHEB Ras homolog, mTORC1 binding JBrowse link 16 15,439,910 15,483,489 RGD:13508589
G RICTOR RPTOR independent companion of MTOR complex 2 JBrowse link 4 69,903,393 70,013,168 RGD:13508589
G RPTOR regulatory associated protein of MTOR complex 1 JBrowse link 9 1,012,512 1,345,872 RGD:13508589
G RRAGB Ras related GTP binding B JBrowse link X 47,323,427 47,361,551 RGD:13508589
G RRAGC Ras related GTP binding C JBrowse link 15 3,875,193 3,892,501 RGD:13508589
G RRAGD Ras related GTP binding D JBrowse link 12 48,583,350 48,625,032 RGD:13508589
G SEC13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 20 8,041,485 8,075,078 RGD:9068941
G SEH1L SEH1 like nucleoporin JBrowse link 7 78,352,153 78,383,546 RGD:9068941
G SLC38A9 solute carrier family 38 member 9 JBrowse link 2 42,921,906 43,004,265 RGD:13508589
G SMCR8 SMCR8-C9orf72 complex subunit RGD:13508589
G WDR24 WD repeat domain 24 JBrowse link 6 39,887,968 39,891,633 RGD:13508589
G WDR59 WD repeat domain 59 JBrowse link 5 75,697,828 75,811,323 RGD:9068941
G XBP1 X-box binding protein 1 JBrowse link 26 22,162,675 22,168,149 RGD:9068941
positive regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEP192 centrosomal protein 192 JBrowse link 7 78,401,273 78,541,918 RGD:13508589
G CLEC16A C-type lectin domain containing 16A JBrowse link 6 31,560,940 31,757,100 RGD:13508589
G GPR137 G protein-coupled receptor 137 JBrowse link 18 52,776,857 52,781,050 RGD:13508589
G GPR137B G protein-coupled receptor 137B JBrowse link 4 3,819,338 3,864,690 RGD:13508589
G GPR137C G protein-coupled receptor 137C JBrowse link 8 28,795,725 28,861,011 RGD:13508589
G KLHL22 kelch like family member 22 JBrowse link 26 30,248,253 30,281,989 RGD:13508589
G LARS1 leucyl-tRNA synthetase 1 JBrowse link 2 40,544,031 40,619,268 RGD:9068941
G PIH1D1 PIH1 domain containing 1 JBrowse link 1 107,045,466 107,051,281 RGD:9068941
G PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 JBrowse link 15 17,789,511 17,793,226 RGD:9068941
G RRAGA Ras related GTP binding A JBrowse link 11 38,886,990 38,888,634 RGD:9068941
G RRAGB Ras related GTP binding B JBrowse link X 47,323,427 47,361,551 RGD:13508589
G RRAGD Ras related GTP binding D JBrowse link 12 48,583,350 48,625,032 RGD:13508589
G SEC13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 20 8,041,485 8,075,078 RGD:13508589
G SEH1L SEH1 like nucleoporin JBrowse link 7 78,352,153 78,383,546 RGD:13508589
G SIK3 SIK family kinase 3 JBrowse link 5 16,623,756 16,733,259 RGD:13508589
G TELO2 telomere maintenance 2 JBrowse link 6 39,309,224 39,320,215 RGD:13508589
positive regulation of TORC2 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIK3 SIK family kinase 3 JBrowse link 5 16,623,756 16,733,259 RGD:13508589
G TELO2 telomere maintenance 2 JBrowse link 6 39,309,224 39,320,215 RGD:13508589
regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C11H9orf72 chromosome 11 C9orf72 homolog JBrowse link 11 45,664,942 45,688,777 RGD:13508589
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 26 23,439,472 23,443,950 RGD:13508589
G DGKQ diacylglycerol kinase theta JBrowse link 3 91,544,350 91,554,494 RGD:9068941
G DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 JBrowse link 7 5,816,839 5,826,194 RGD:9068941
G RRAGC Ras related GTP binding C JBrowse link 15 3,875,193 3,892,501 RGD:13508589
G SMCR8 SMCR8-C9orf72 complex subunit RGD:13508589
regulation of TORC2 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PIH1D1 PIH1 domain containing 1 JBrowse link 1 107,045,466 107,051,281 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16041
    signaling 5936
      signal transduction 5380
        intracellular signal transduction 2457
          regulation of intracellular signal transduction 1614
            regulation of TOR signaling 101
              negative regulation of TOR signaling + 44
              positive regulation of TOR signaling + 43
              regulation of TORC1 signaling + 39
              regulation of TORC2 signaling + 3
Path 2
Term Annotations click to browse term
  biological_process 16041
    biological regulation 11410
      regulation of biological process 10829
        regulation of cellular process 10367
          signal transduction 5380
            regulation of signal transduction 2794
              regulation of intracellular signal transduction 1614
                regulation of TOR signaling 101
                  negative regulation of TOR signaling + 44
                  positive regulation of TOR signaling + 43
                  regulation of TORC1 signaling + 39
                  regulation of TORC2 signaling + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.