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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of TOR signaling
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Accession:GO:0032006 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of TOR signaling.
Synonyms:exact_synonym: regulation of TOR signaling pathway;   regulation of TOR signalling pathway;   regulation of target of rapamycin signaling pathway;   regulation of target of rapamycin signalling pathway
 related_synonym: regulation of TOR signaling cascade


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regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARAF A-Raf proto-oncogene, serine/threonine kinase JBrowse link X 47,561,100 47,571,921 RGD:2290271
G DDIT4 DNA damage inducible transcript 4 JBrowse link 10 72,273,924 72,276,036 RGD:2290271
G FAM83D family with sequence similarity 83 member D JBrowse link 20 38,926,417 38,953,106 RGD:2290271
G FBXO9 F-box protein 9 JBrowse link 6 53,057,807 53,100,873 RGD:2290271
G FLCN folliculin JBrowse link 17 17,206,946 17,237,188 RGD:2290271
G GBA glucosylceramidase beta JBrowse link 1 155,234,452 155,244,627 RGD:2290271
G GNA12 G protein subunit alpha 12 JBrowse link 7 2,728,105 2,844,308 RGD:2290271
G GPAT3 glycerol-3-phosphate acyltransferase 3 JBrowse link 4 83,535,634 83,605,875 RGD:2290271
G ITFG2 integrin alpha FG-GAP repeat containing 2 JBrowse link 12 2,812,644 2,859,907 RGD:2290271
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link 6 51,614,685 52,087,625 RGD:2290271
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase JBrowse link 17 35,005,990 35,089,226 RGD:2290271
G RHEB Ras homolog, mTORC1 binding JBrowse link 7 151,466,012 151,519,895 RGD:9068941
G ROS1 ROS proto-oncogene 1, receptor tyrosine kinase JBrowse link 6 117,287,353 117,426,065 RGD:2290271
G RRAGB Ras related GTP binding B JBrowse link X 55,717,747 55,760,209 RGD:2290271
G RRAGC Ras related GTP binding C JBrowse link 1 38,838,198 38,859,772 RGD:2290271
G SLC7A1 solute carrier family 7 member 1 JBrowse link 13 29,509,410 29,595,688 RGD:9068941
G SLC7A3 solute carrier family 7 member 3 JBrowse link X 70,925,579 70,931,096 RGD:9068941
G TBCK TBC1 domain containing kinase JBrowse link 4 106,041,599 106,316,683 RGD:2290271
G TELO2 telomere maintenance 2 JBrowse link 16 1,493,345 1,510,459 RGD:2290271
G TMEM127 transmembrane protein 127 JBrowse link 2 96,248,514 96,265,997 RGD:2290271
G TREM2 triggering receptor expressed on myeloid cells 2 JBrowse link 6 41,158,508 41,163,116 RGD:2290271
G TTI1 TELO2 interacting protein 1 JBrowse link 20 37,983,014 38,033,461 RGD:2290271
G ZMPSTE24 zinc metallopeptidase STE24 JBrowse link 1 40,258,078 40,294,180 RGD:2290271
negative regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC006486.1 novel protein RGD:2290271
G AKT1S1 AKT1 substrate 1 JBrowse link 19 49,869,033 49,878,356 RGD:2290271
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 11 13,276,552 13,387,268 RGD:2290271
G CRYBA1 crystallin beta A1 JBrowse link 17 29,246,859 29,254,494 RGD:2290271
G DDIT4 DNA damage inducible transcript 4 JBrowse link 10 72,273,924 72,276,036 RGD:2290271
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 22 31,753,968 31,908,033 RGD:2290271
G DEPTOR DEP domain containing MTOR interacting protein JBrowse link 8 119,873,655 120,050,918 RGD:2290271
G EPM2A EPM2A glucan phosphatase, laforin JBrowse link 6 145,382,540 145,736,023 RGD:2290271
G FLCN folliculin JBrowse link 17 17,206,946 17,237,188 RGD:2290271
G FNIP1 folliculin interacting protein 1 JBrowse link 5 131,641,714 131,797,017 RGD:2290271
G GSK3A glycogen synthase kinase 3 alpha JBrowse link 19 42,230,186 42,243,330 RGD:2290271
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 119,821,321 120,095,823 RGD:9068941
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 14 61,695,513 61,748,259 RGD:2290271
G MAPKAPK5 MAPK activated protein kinase 5 JBrowse link 12 111,842,228 111,902,222 RGD:2290271
G MINAR1 membrane integral NOTCH2 associated receptor 1 JBrowse link 15 79,411,557 79,472,304 RGD:2290271
G MTM1 myotubularin 1 JBrowse link X 150,562,658 150,673,143 RGD:2290271
G NPRL2 NPR2 like, GATOR1 complex subunit JBrowse link 3 50,347,330 50,350,821 RGD:2290271
G NPRL3 NPR3 like, GATOR1 complex subunit JBrowse link 16 85,386 138,698 RGD:2290271
G PDCD6 programmed cell death 6 JBrowse link 5 271,621 314,974 RGD:2290271
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 5 40,759,379 40,798,195 RGD:2290271
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 1 56,645,314 56,715,335 RGD:2290271
G SH3BP4 SH3 domain binding protein 4 JBrowse link 2 234,952,017 235,055,714 RGD:2290271
G SIRT1 sirtuin 1 JBrowse link 10 67,884,656 67,918,390 RGD:2290271
G TBC1D7 TBC1 domain family member 7 JBrowse link 6 13,266,542 13,328,583 RGD:2290271
G TBC1D7 TBC1 domain family member 7 JBrowse link 6 13,304,951 13,328,583 RGD:2290271
G TMEM127 transmembrane protein 127 JBrowse link 2 96,248,514 96,265,997 RGD:2290271
G TNFAIP8L1 TNF alpha induced protein 8 like 1 JBrowse link 19 4,639,505 4,655,568 RGD:2290271
G TSC1 TSC complex subunit 1 JBrowse link 9 132,891,349 132,945,269 RGD:2290271
G TSC2 TSC complex subunit 2 JBrowse link 16 2,047,804 2,089,491 RGD:2290271
G UBR1 ubiquitin protein ligase E3 component n-recognin 1 JBrowse link 15 42,942,897 43,106,038 RGD:2290271
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 JBrowse link 6 42,563,954 42,693,505 RGD:2290271
negative regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC004997.1 novel protein RGD:2290271
G ATM ATM serine/threonine kinase JBrowse link 11 108,222,484 108,369,102 RGD:2290271
G BMT2 base methyltransferase of 25S rRNA 2 homolog JBrowse link 7 112,819,147 112,939,875 RGD:2290271
G C12orf66 chromosome 12 open reading frame 66 JBrowse link 12 64,186,312 64,222,296 RGD:2290271
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 22 30,285,117 30,289,505 RGD:2290271
G CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 JBrowse link 7 74,964,693 75,031,531 RGD:2290271
G CASTOR3 CASTOR family member 3 JBrowse link 7 100,200,653 100,272,232 RGD:2290271
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 22 31,753,968 31,908,033 RGD:2290271
G FNIP1 folliculin interacting protein 1 JBrowse link 5 131,641,714 131,797,017 RGD:2290271
G FNIP2 folliculin interacting protein 2 JBrowse link 4 158,769,026 158,908,050 RGD:2290271
G ITFG2 integrin alpha FG-GAP repeat containing 2 JBrowse link 12 2,812,644 2,859,907 RGD:2290271
G KPTN kaptin, actin binding protein JBrowse link 19 47,475,141 47,486,792 RGD:2290271
G RNF152 ring finger protein 152 JBrowse link 18 61,808,067 61,894,420 RGD:2290271
G SESN1 sestrin 1 JBrowse link 6 108,984,309 109,094,846 RGD:2290271
G SESN2 sestrin 2 JBrowse link 1 28,259,452 28,282,491 RGD:2290271
G SESN3 sestrin 3 JBrowse link 11 95,165,513 95,232,536 RGD:2290271
G SPAAR small regulatory polypeptide of amino acid response JBrowse link 9 35,909,490 35,911,686 RGD:2290271
G STK11 serine/threonine kinase 11 JBrowse link 19 1,205,778 1,228,431 RGD:2290271
G SZT2 SZT2 subunit of KICSTOR complex JBrowse link 1 43,389,884 43,454,247 RGD:2290271
G TSC2 TSC complex subunit 2 JBrowse link 16 2,047,804 2,089,491 RGD:9068941
positive regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT3 AKT serine/threonine kinase 3 JBrowse link 1 243,488,233 243,851,079 RGD:9068941
G FLCN folliculin JBrowse link 17 17,206,946 17,237,188 RGD:2290271
G FNIP1 folliculin interacting protein 1 JBrowse link 5 131,641,714 131,797,017 RGD:2290271
G GAS6 growth arrest specific 6 JBrowse link 13 113,820,549 113,864,076 RGD:2290271
G GOLPH3 golgi phosphoprotein 3 JBrowse link 5 32,124,711 32,174,319 RGD:2290271
G HDAC3 histone deacetylase 3 JBrowse link 5 141,620,876 141,636,856 RGD:2290271
G HTR6 5-hydroxytryptamine receptor 6 JBrowse link 1 19,664,875 19,680,966 RGD:2290271
G KDR kinase insert domain receptor JBrowse link 4 55,078,481 55,125,595 RGD:9068941
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 JBrowse link 11 72,097,292 72,103,297 RGD:2290271
G LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 JBrowse link 1 156,054,782 156,058,506 RGD:2290271
G LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 JBrowse link 4 99,878,336 99,894,546 RGD:2290271
G LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 JBrowse link 7 100,140,177 100,154,212 RGD:2290271
G LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 1 110,401,253 110,407,924 RGD:2290271
G LARS1 leucyl-tRNA synthetase 1 JBrowse link 5 146,113,026 146,182,787 RGD:2290271
G LEP leptin JBrowse link 7 128,241,201 128,257,629 RGD:2290271
G LIN28A lin-28 homolog A JBrowse link 1 26,410,778 26,429,728 RGD:2290271
G MIOS meiosis regulator for oocyte development JBrowse link 7 7,566,875 7,609,144 RGD:2290271
G MLST8 MTOR associated protein, LST8 homolog JBrowse link 16 2,204,628 2,209,453 RGD:2290271
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 179,148,114 179,240,093 RGD:2290271
G RELN reelin JBrowse link 7 103,471,784 103,989,658 RGD:2290271
G RHEB Ras homolog, mTORC1 binding JBrowse link 7 151,466,012 151,519,895 RGD:2290271
G RICTOR RPTOR independent companion of MTOR complex 2 JBrowse link 5 38,937,920 39,074,421 RGD:2290271
G RPTOR regulatory associated protein of MTOR complex 1 JBrowse link 17 80,544,838 80,966,368 RGD:2290271
G RRAGA Ras related GTP binding A JBrowse link 9 19,049,427 19,051,025 RGD:2290271
G RRAGB Ras related GTP binding B JBrowse link X 55,717,747 55,760,209 RGD:2290271
G RRAGC Ras related GTP binding C JBrowse link 1 38,838,198 38,859,772 RGD:2290271
G RRAGD Ras related GTP binding D JBrowse link 6 89,363,509 89,412,273 RGD:2290271
G SEC13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 3 10,300,929 10,321,188 RGD:2290271
G SEH1L SEH1 like nucleoporin JBrowse link 18 12,947,984 12,987,665 RGD:2290271
G SLC38A9 solute carrier family 38 member 9 JBrowse link 5 55,625,845 55,712,343 RGD:2290271
G SMCR8 SMCR8-C9orf72 complex subunit JBrowse link 17 18,315,293 18,328,056 RGD:2290271
G TREM2 triggering receptor expressed on myeloid cells 2 JBrowse link 6 41,158,508 41,163,116 RGD:2290271
G WDR24 WD repeat domain 24 JBrowse link 16 684,622 690,661 RGD:2290271
G WDR59 WD repeat domain 59 JBrowse link 16 74,871,362 74,985,146 RGD:2290271
G XBP1 X-box binding protein 1 JBrowse link 22 28,794,560 28,800,572 RGD:2290271
positive regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLEC16A C-type lectin domain containing 16A JBrowse link 16 10,944,488 11,193,272 RGD:2290271
G FLCN folliculin JBrowse link 17 17,206,946 17,237,188 RGD:2290271
G GPR137 G protein-coupled receptor 137 JBrowse link 11 64,270,337 64,289,500 RGD:2290271
G GPR137B G protein-coupled receptor 137B JBrowse link 1 236,142,529 236,213,535 RGD:2290271
G GPR137C G protein-coupled receptor 137C JBrowse link 14 52,552,836 52,637,713 RGD:2290271
G KLHL22 kelch like family member 22 JBrowse link 22 20,441,519 20,497,305 RGD:2290271
G LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 1 110,401,253 110,407,924 RGD:2290271
G LARS1 leucyl-tRNA synthetase 1 JBrowse link 5 146,113,026 146,182,787 RGD:2290271
G PIH1D1 PIH1 domain containing 1 JBrowse link 19 49,446,298 49,452,392 RGD:2290271
G PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 JBrowse link 14 20,457,681 20,461,612 RGD:2290271
G RRAGA Ras related GTP binding A JBrowse link 9 19,049,427 19,051,025 RGD:2290271
G RRAGB Ras related GTP binding B JBrowse link X 55,717,747 55,760,209 RGD:2290271
G RRAGD Ras related GTP binding D JBrowse link 6 89,363,509 89,412,273 RGD:2290271
G SEC13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 3 10,300,929 10,321,188 RGD:2290271
G SEH1L SEH1 like nucleoporin JBrowse link 18 12,947,984 12,987,665 RGD:2290271
G SIK3 SIK family kinase 3 JBrowse link 11 116,843,410 117,098,453 RGD:2290271
G TELO2 telomere maintenance 2 JBrowse link 16 1,493,345 1,510,459 RGD:2290271
positive regulation of TORC2 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIK3 SIK family kinase 3 JBrowse link 11 116,843,410 117,098,453 RGD:2290271
G TELO2 telomere maintenance 2 JBrowse link 16 1,493,345 1,510,459 RGD:2290271
regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C9orf72 C9orf72-SMCR8 complex subunit JBrowse link 9 27,546,546 27,573,866 RGD:2290271
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 22 30,285,117 30,289,505 RGD:2290271
G DGKQ diacylglycerol kinase theta JBrowse link 4 958,887 973,569 RGD:2290271
G DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 JBrowse link 1 206,635,536 206,655,175 RGD:2290271
G RRAGC Ras related GTP binding C JBrowse link 1 38,838,198 38,859,772 RGD:2290271
G SMCR8 SMCR8-C9orf72 complex subunit JBrowse link 17 18,315,293 18,328,056 RGD:2290271
regulation of TORC2 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PIH1D1 PIH1 domain containing 1 JBrowse link 19 49,446,298 49,452,392 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18542
    signaling 7164
      signal transduction 6519
        intracellular signal transduction 2957
          regulation of intracellular signal transduction 1962
            regulation of TOR signaling 107
              negative regulation of TOR signaling + 48
              positive regulation of TOR signaling + 44
              regulation of TORC1 signaling + 42
              regulation of TORC2 signaling + 3
Path 2
Term Annotations click to browse term
  biological_process 18542
    biological regulation 13176
      regulation of biological process 12532
        regulation of cellular process 11931
          signal transduction 6519
            regulation of signal transduction 3352
              regulation of intracellular signal transduction 1962
                regulation of TOR signaling 107
                  negative regulation of TOR signaling + 48
                  positive regulation of TOR signaling + 44
                  regulation of TORC1 signaling + 42
                  regulation of TORC2 signaling + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.