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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of TOR signaling
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Accession:GO:0032006 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of TOR signaling.
Synonyms:exact_synonym: regulation of TOR signaling pathway;   regulation of TOR signalling pathway;   regulation of target of rapamycin signaling pathway;   regulation of target of rapamycin signalling pathway
 related_synonym: regulation of TOR signaling cascade


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regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Araf Araf proto-oncogene, serine/threonine kinase JBrowse link X 20,797,707 20,860,521 RGD:2290270
G Ddit4 DNA-damage-inducible transcript 4 JBrowse link 10 59,949,675 59,951,770 RGD:2290270
G Fam83d family with sequence similarity 83, member D JBrowse link 2 158,768,099 158,786,637 RGD:2290270
G Fbxo9 f-box protein 9 JBrowse link 9 78,081,499 78,109,065 RGD:2290270
G Flcn folliculin JBrowse link 11 59,791,408 59,810,039 RGD:2290270
G Gba glucosidase, beta, acid JBrowse link 3 89,202,905 89,208,873 RGD:2290270
G Gna12 guanine nucleotide binding protein, alpha 12 JBrowse link 5 140,759,944 140,830,431 RGD:2290270
G Gpat3 glycerol-3-phosphate acyltransferase 3 JBrowse link 5 100,845,665 100,899,102 RGD:2290270
G Itfg2 integrin alpha FG-GAP repeat containing 2 JBrowse link 6 128,409,047 128,424,927 RGD:2290270
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 JBrowse link 3 137,918,555 137,928,762 RGD:2290270
G Pkhd1 polycystic kidney and hepatic disease 1 JBrowse link 1 20,057,779 20,618,082 RGD:2290270
G Rheb Ras homolog enriched in brain JBrowse link 5 24,802,823 24,842,361 RGD:2290270
G Ros1 Ros1 proto-oncogene JBrowse link 10 52,044,863 52,195,398 RGD:2290270
G Rragb Ras-related GTP binding B JBrowse link X 153,137,644 153,190,192 RGD:2290270
G Rragc Ras-related GTP binding C JBrowse link 4 123,917,433 123,936,997 RGD:2290270
G Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 JBrowse link 5 148,327,410 148,399,904 RGD:2290270
G Slc7a3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 JBrowse link X 101,079,146 101,090,452 RGD:2290270
G Tbck TBC1 domain containing kinase JBrowse link 3 132,684,113 132,841,688 RGD:2290270
G Telo2 telomere maintenance 2 JBrowse link 17 25,099,569 25,115,974 RGD:2290270
G Tmem127 transmembrane protein 127 JBrowse link 2 127,247,904 127,261,108 RGD:2290270
G Trem2 triggering receptor expressed on myeloid cells 2 JBrowse link 17 48,346,401 48,352,276 RGD:2290270
G Tti1 TELO2 interacting protein 1 JBrowse link 2 157,981,803 158,028,475 RGD:2290270
G Zmpste24 zinc metallopeptidase, STE24 JBrowse link 4 121,059,237 121,098,249 RGD:2290270
negative regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1s1 AKT1 substrate 1 (proline-rich) JBrowse link 7 44,849,224 44,855,421 RGD:2290270
G Arntl aryl hydrocarbon receptor nuclear translocator-like JBrowse link 7 113,178,471 113,314,126 RGD:2290270
G Cryba1 crystallin, beta A1 JBrowse link 11 77,718,614 77,725,293 RGD:2290270
G Ddit4 DNA-damage-inducible transcript 4 JBrowse link 10 59,949,675 59,951,770 RGD:2290270
G Depdc5 DEP domain containing 5 JBrowse link 5 32,863,646 32,994,233 RGD:2290270
G Deptor DEP domain containing MTOR-interacting protein JBrowse link 15 55,112,317 55,259,273 RGD:2290270
G Epm2a epilepsy, progressive myoclonic epilepsy, type 2 gene alpha JBrowse link 10 11,342,691 11,459,664 RGD:2290270
G Flcn folliculin JBrowse link 11 59,791,408 59,810,039 RGD:2290270
G Fnip1 folliculin interacting protein 1 JBrowse link 11 54,438,107 54,518,241 RGD:2290270
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 7 25,228,258 25,237,851 RGD:2290270
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 16 38,089,001 38,246,084 RGD:2290270
G Hif1a hypoxia inducible factor 1, alpha subunit JBrowse link 12 73,901,324 73,947,554 RGD:2290270
G Mapkapk5 MAP kinase-activated protein kinase 5 JBrowse link 5 121,525,051 121,545,892 RGD:2290270
G Minar1 membrane integral NOTCH2 associated receptor 1 JBrowse link 9 89,587,208 89,623,887 RGD:2290270
G Mtm1 X-linked myotubular myopathy gene 1 JBrowse link X 71,210,767 71,315,413 RGD:2290270
G Nprl2 NPR2 like, GATOR1 complex subunit JBrowse link 9 107,542,177 107,545,706 RGD:2290270
G Nprl3 nitrogen permease regulator-like 3 JBrowse link 11 32,231,963 32,267,707 RGD:2290270
G Pdcd6 programmed cell death 6 JBrowse link 13 74,303,121 74,317,326 RGD:2290270
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit JBrowse link 15 5,143,861 5,181,899 RGD:2290270
G Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit JBrowse link 4 105,029,649 105,109,898 RGD:2290270
G Sh3bp4 SH3-domain binding protein 4 JBrowse link 1 89,070,333 89,155,087 RGD:2290270
G Sirt1 sirtuin 1 JBrowse link 10 63,319,005 63,339,035 RGD:2290270
G Tbc1d7 TBC1 domain family, member 7 JBrowse link 13 43,151,740 43,171,501 RGD:2290270
G Tmem127 transmembrane protein 127 JBrowse link 2 127,247,904 127,261,108 RGD:2290270
G Tnfaip8l1 tumor necrosis factor, alpha-induced protein 8-like 1 JBrowse link 17 56,162,439 56,184,249 RGD:2290270
G Tsc1 TSC complex subunit 1 JBrowse link 2 28,640,993 28,691,172 RGD:2290270
G Tsc2 TSC complex subunit 2 JBrowse link 17 24,595,816 24,632,676 RGD:2290270
G Ubr1 ubiquitin protein ligase E3 component n-recognin 1 JBrowse link 2 120,860,272 120,970,760 RGD:2290270
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 JBrowse link 17 46,928,291 47,010,886 RGD:2290270
negative regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ataxia telangiectasia mutated JBrowse link 9 53,437,122 53,536,828 RGD:2290270
G BC048403 cDNA sequence BC048403 JBrowse link 10 121,739,930 121,752,865 RGD:2290270
G Bmt2 base methyltransferase of 25S rRNA 2 JBrowse link 6 13,625,675 13,677,966 RGD:2290270
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 11 4,218,166 4,222,409 RGD:2290270
G Castor2 cytosolic arginine sensor for mTORC1 subunit 2 JBrowse link 5 134,099,748 134,141,782 RGD:2290270
G Depdc5 DEP domain containing 5 JBrowse link 5 32,863,646 32,994,233 RGD:2290270
G Fnip1 folliculin interacting protein 1 JBrowse link 11 54,438,107 54,518,241 RGD:2290270
G Fnip2 folliculin interacting protein 2 JBrowse link 3 79,455,971 79,568,151 RGD:2290270
G Itfg2 integrin alpha FG-GAP repeat containing 2 JBrowse link 6 128,409,047 128,424,927 RGD:2290270
G Kptn kaptin JBrowse link 7 16,119,876 16,127,516 RGD:2290270
G Rnf152 ring finger protein 152 JBrowse link 1 105,276,917 105,356,991 RGD:2290270
G Sesn1 sestrin 1 JBrowse link 10 41,810,574 41,908,436 RGD:2290270
G Sesn2 sestrin 2 JBrowse link 4 132,492,804 132,510,456 RGD:2290270
G Sesn3 sestrin 3 JBrowse link 9 14,276,301 14,326,134 RGD:2290270
G Spaar small regulatory polypeptide of amino acid response JBrowse link 4 43,730,034 43,734,534 RGD:2290270
G Stk11 serine/threonine kinase 11 JBrowse link 10 80,115,767 80,130,679 RGD:2290270
G Szt2 SZT2 subunit of KICSTOR complex JBrowse link 4 118,362,740 118,409,286 RGD:2290270
G Tsc2 TSC complex subunit 2 JBrowse link 17 24,595,816 24,632,676 RGD:2290270
positive regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt3 thymoma viral proto-oncogene 3 JBrowse link 1 177,020,076 177,261,781 RGD:2290270
G Flcn folliculin JBrowse link 11 59,791,408 59,810,039 RGD:2290270
G Fnip1 folliculin interacting protein 1 JBrowse link 11 54,438,107 54,518,241 RGD:2290270
G Gas6 growth arrest specific 6 JBrowse link 8 13,465,374 13,494,535 RGD:2290270
G Golph3 golgi phosphoprotein 3 JBrowse link 15 12,320,488 12,351,601 RGD:2290270
G Hdac3 histone deacetylase 3 JBrowse link 18 37,936,971 37,955,015 RGD:2290270
G Htr6 5-hydroxytryptamine (serotonin) receptor 6 JBrowse link 4 139,059,706 139,075,570 RGD:2290270
G Kdr kinase insert domain protein receptor JBrowse link 5 75,932,827 75,979,072 RGD:2290270
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 JBrowse link 7 101,905,837 101,911,903 RGD:2290270
G Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 JBrowse link 3 88,549,819 88,552,951 RGD:2290270
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 JBrowse link 3 137,918,555 137,928,762 RGD:2290270
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 JBrowse link 5 138,255,482 138,259,395 RGD:2290270
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 3 107,278,858 107,284,082 RGD:2290270
G Lars leucyl-tRNA synthetase JBrowse link 18 42,202,298 42,262,237 RGD:2290270
G Lep leptin JBrowse link 6 29,060,221 29,073,876 RGD:2290270
G Lin28a lin-28 homolog A (C. elegans) JBrowse link 4 134,003,330 134,019,196 RGD:2290270
G Mios meiosis regulator for oocyte development JBrowse link 6 8,209,111 8,240,573 RGD:2290270
G Mlst8 MTOR associated protein, LST8 homolog (S. cerevisiae) JBrowse link 17 24,473,550 24,479,114 RGD:2290270
G Reln reelin JBrowse link 5 21,884,454 22,344,705 RGD:2290270
G Rheb Ras homolog enriched in brain JBrowse link 5 24,802,823 24,842,361 RGD:2290270
G Rictor RPTOR independent companion of MTOR, complex 2 JBrowse link 15 6,708,349 6,800,401 RGD:2290270
G Rptor regulatory associated protein of MTOR, complex 1 JBrowse link 11 119,602,905 119,899,591 RGD:2290270
G Rraga Ras-related GTP binding A JBrowse link 4 86,575,673 86,577,285 RGD:2290270
G Rragb Ras-related GTP binding B JBrowse link X 153,137,644 153,190,192 RGD:2290270
G Rragc Ras-related GTP binding C JBrowse link 4 123,917,433 123,936,997 RGD:2290270
G Rragd Ras-related GTP binding D JBrowse link 4 32,982,998 33,022,180 RGD:2290270
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 6 113,728,052 113,740,681 RGD:2290270
G Seh1l SEH1-like (S. cerevisiae JBrowse link 18 67,774,876 67,795,487 RGD:2290270
G Slc38a9 solute carrier family 38, member 9 JBrowse link 13 112,656,189 112,738,752 RGD:2290270
G Smcr8 Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) JBrowse link 11 60,777,525 60,788,287 RGD:2290270
G Trem2 triggering receptor expressed on myeloid cells 2 JBrowse link 17 48,346,401 48,352,276 RGD:2290270
G Wdr24 WD repeat domain 24 JBrowse link 17 25,823,627 25,828,730 RGD:2290270
G Wdr59 WD repeat domain 59 JBrowse link 8 111,448,781 111,522,128 RGD:2290270
G Xbp1 X-box binding protein 1 JBrowse link 11 5,520,641 5,525,993 RGD:2290270
positive regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clec16a C-type lectin domain family 16, member A JBrowse link 16 10,545,309 10,744,878 RGD:2290270
G Flcn folliculin JBrowse link 11 59,791,408 59,810,039 RGD:2290270
G Gpr137 G protein-coupled receptor 137 JBrowse link 19 6,938,057 6,942,450 RGD:2290270
G Gpr137b G protein-coupled receptor 137B JBrowse link 13 13,357,620 13,393,644 RGD:2290270
G Gpr137c G protein-coupled receptor 137C JBrowse link 14 45,219,685 45,282,735 RGD:2290270
G Klhl22 kelch-like 22 JBrowse link 16 17,759,621 17,793,382 RGD:2290270
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 3 107,278,858 107,284,082 RGD:2290270
G Lars leucyl-tRNA synthetase JBrowse link 18 42,202,298 42,262,237 RGD:2290270
G Pih1d1 PIH1 domain containing 1 JBrowse link 7 45,150,613 45,160,065 RGD:2290270
G Pip4p1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 JBrowse link 14 50,927,215 50,931,010 RGD:2290270
G Rraga Ras-related GTP binding A JBrowse link 4 86,575,673 86,577,285 RGD:2290270
G Rragb Ras-related GTP binding B JBrowse link X 153,137,644 153,190,192 RGD:2290270
G Rragd Ras-related GTP binding D JBrowse link 4 32,982,998 33,022,180 RGD:2290270
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 6 113,728,052 113,740,681 RGD:2290270
G Seh1l SEH1-like (S. cerevisiae JBrowse link 18 67,774,876 67,795,487 RGD:2290270
G Sik3 SIK family kinase 3 JBrowse link 9 46,012,820 46,224,194 RGD:2290270
G Telo2 telomere maintenance 2 JBrowse link 17 25,099,569 25,115,974 RGD:2290270
positive regulation of TORC2 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sik3 SIK family kinase 3 JBrowse link 9 46,012,820 46,224,194 RGD:2290270
G Telo2 telomere maintenance 2 JBrowse link 17 25,099,569 25,115,974 RGD:2290270
regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C9orf72 C9orf72, member of C9orf72-SMCR8 complex JBrowse link 4 35,191,285 35,226,153 RGD:2290270
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 11 4,218,166 4,222,409 RGD:2290270
G Dgkq diacylglycerol kinase, theta JBrowse link 5 108,647,044 108,660,830 RGD:2290270
G Dyrk3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 JBrowse link 1 131,128,441 131,138,234 RGD:2290270
G Rragc Ras-related GTP binding C JBrowse link 4 123,917,433 123,936,997 RGD:2290270
G Smcr8 Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) JBrowse link 11 60,777,525 60,788,287 RGD:2290270
regulation of TORC2 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pih1d1 PIH1 domain containing 1 JBrowse link 7 45,150,613 45,160,065 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23163
    signaling 6906
      signal transduction 6283
        intracellular signal transduction 2541
          regulation of intracellular signal transduction 1701
            regulation of TOR signaling 101
              negative regulation of TOR signaling + 44
              positive regulation of TOR signaling + 43
              regulation of TORC1 signaling + 40
              regulation of TORC2 signaling + 3
Path 2
Term Annotations click to browse term
  biological_process 23163
    biological regulation 12767
      regulation of biological process 12161
        regulation of cellular process 11599
          signal transduction 6283
            regulation of signal transduction 2977
              regulation of intracellular signal transduction 1701
                regulation of TOR signaling 101
                  negative regulation of TOR signaling + 44
                  positive regulation of TOR signaling + 43
                  regulation of TORC1 signaling + 40
                  regulation of TORC2 signaling + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.