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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of TOR signaling
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Accession:GO:0032006 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of TOR signaling.
Synonyms:exact_synonym: regulation of TOR signaling pathway;   regulation of TOR signalling pathway;   regulation of target of rapamycin signaling pathway;   regulation of target of rapamycin signalling pathway
 related_synonym: regulation of TOR signaling cascade


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regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARAF A-Raf proto-oncogene, serine/threonine kinase JBrowse link X 42,078,202 42,090,250 RGD:9068941
G DDIT4 DNA damage inducible transcript 4 JBrowse link 14 75,117,708 75,119,907 RGD:14298760
G FAM83D family with sequence similarity 83 member D JBrowse link 17 41,868,982 41,892,222 RGD:14298760
G FBXO9 F-box protein 9 JBrowse link 7 46,723,579 46,748,132 RGD:9068941
G FLCN folliculin JBrowse link 12 61,029,186 61,045,400 RGD:9068941
G GBA glucosylceramidase beta JBrowse link 4 94,583,905 94,606,689 RGD:14298760
G GNA12 G protein subunit alpha 12 JBrowse link 3 2,002,494 2,105,937 RGD:14298760
G GPAT3 glycerol-3-phosphate acyltransferase 3 JBrowse link 8 134,912,493 135,002,140 RGD:14298760
G ITFG2 integrin alpha FG-GAP repeat containing 2 JBrowse link 5 67,292,901 67,306,208 RGD:14298760
G LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 JBrowse link 8 120,625,897 120,642,630 RGD:14298760
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link 7 45,447,354 45,925,141 RGD:14298760
G RHEB Ras homolog, mTORC1 binding JBrowse link 18 5,779,439 5,821,839 RGD:9068941
G ROS1 ROS proto-oncogene 1, receptor tyrosine kinase JBrowse link 1 44,409,877 44,535,784 RGD:14298760
G RRAGB Ras related GTP binding B JBrowse link X 48,286,584 48,330,196 RGD:9068941
G RRAGC Ras related GTP binding C JBrowse link 6 94,785,906 94,803,017 RGD:9068941
G SLC7A1 solute carrier family 7 member 1 JBrowse link 11 6,538,053 6,604,654 RGD:9068941
G SLC7A3 solute carrier family 7 member 3 JBrowse link X 56,937,081 56,942,331 RGD:9068941
G TBCK TBC1 domain containing kinase JBrowse link 8 115,476,776 115,703,011 RGD:14298760
G TELO2 telomere maintenance 2 JBrowse link 3 40,372,215 40,386,777 RGD:9068941
G TMEM127 transmembrane protein 127 JBrowse link 3 46,966,858 47,017,659 RGD:14298760
G TREM2 triggering receptor expressed on myeloid cells 2 JBrowse link 7 36,465,921 36,471,509 RGD:9068941
G TTI1 TELO2 interacting protein 1 JBrowse link 17 41,047,408 41,094,038 RGD:14298760
G ZMPSTE24 zinc metallopeptidase STE24 JBrowse link 6 96,008,307 96,057,131 RGD:14298760
negative regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1S1 AKT1 substrate 1 JBrowse link 6 54,881,581 54,890,917 RGD:14298760
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 2 45,895,637 46,025,174 RGD:14298760
G COPS3 COP9 signalosome subunit 3 JBrowse link 12 61,000,562 61,023,920 RGD:14298760
G CRYBA1 crystallin beta A1 JBrowse link 12 45,466,051 45,473,110 RGD:9068941
G DDIT4 DNA damage inducible transcript 4 JBrowse link 14 75,117,708 75,119,907 RGD:14298760
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 14 48,421,788 48,523,530 RGD:14298760
G DEPTOR DEP domain containing MTOR interacting protein JBrowse link 4 18,969,509 19,180,131 RGD:14298760
G EPM2A EPM2A glucan phosphatase, laforin JBrowse link 1 19,806,363 19,893,350 RGD:9068941
G FLCN folliculin JBrowse link 12 61,029,186 61,045,400 RGD:9068941
G FNIP1 folliculin interacting protein 1 JBrowse link 2 133,958,112 134,093,408 RGD:9068941
G GSK3A glycogen synthase kinase 3 alpha JBrowse link 6 49,690,319 49,700,735 RGD:14298760
G GSK3B glycogen synthase kinase 3 beta JBrowse link 13 140,136,109 140,370,197 RGD:9068941
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 1 190,625,436 190,673,926 RGD:14298760
G MAPKAPK5 MAPK activated protein kinase 5 JBrowse link 14 39,852,537 39,885,898 RGD:9068941
G MINAR1 membrane integral NOTCH2 associated receptor 1 JBrowse link 7 48,501,067 48,539,300 RGD:14298760
G MTM1 myotubularin 1 JBrowse link X 122,286,904 122,379,302 RGD:14298760
G NPRL2 NPR2 like, GATOR1 complex subunit JBrowse link 13 32,830,895 32,834,205 RGD:9068941
G NPRL3 NPR3 like, GATOR1 complex subunit JBrowse link 3 41,478,465 41,540,719 RGD:14298760
G PDCD6 programmed cell death 6 JBrowse link 16 79,818,960 79,832,272 RGD:9068941
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 16 25,745,902 25,783,524 RGD:14298760
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 6 155,683,392 155,754,283 RGD:14298760
G SH3BP4 SH3 domain binding protein 4 JBrowse link 15 135,003,501 135,094,801 RGD:14298760
G SIRT1 sirtuin 1 JBrowse link 14 71,091,167 71,126,351 RGD:14298760
G TBC1D7 TBC1 domain family member 7 JBrowse link 7 9,685,273 9,708,781 RGD:14298760
G TMEM127 transmembrane protein 127 JBrowse link 3 46,966,858 47,017,659 RGD:14298760
G TNFAIP8L1 TNF alpha induced protein 8 like 1 JBrowse link 2 74,203,753 74,220,811 RGD:14298760
G TSC1 TSC complex subunit 1 JBrowse link 1 272,636,530 272,685,948 RGD:14298760
G TSC2 TSC complex subunit 2 JBrowse link 3 39,898,924 39,935,579 RGD:14298760
G UBR1 ubiquitin protein ligase E3 component n-recognin 1 JBrowse link 1 128,319,311 128,474,330 RGD:14298760
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 JBrowse link 7 37,655,808 37,785,301 RGD:14298760
negative regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATM ATM serine/threonine kinase JBrowse link 9 36,620,656 36,759,555 RGD:14298760
G BMT2 base methyltransferase of 25S rRNA 2 homolog JBrowse link 18 32,798,278 32,900,769 RGD:14298760
G C5H12orf66 chromosome 5 C12orf66 homolog JBrowse link 5 28,656,227 28,679,095 RGD:14298760
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 14 47,261,905 47,266,729 RGD:14298760
G CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 JBrowse link 3 11,956,289 12,039,913 RGD:9068941
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 14 48,421,788 48,523,530 RGD:9068941
G FNIP1 folliculin interacting protein 1 JBrowse link 2 133,958,112 134,093,408 RGD:14298760
G FNIP2 folliculin interacting protein 2 JBrowse link 8 47,702,877 47,838,541 RGD:14298760
G ITFG2 integrin alpha FG-GAP repeat containing 2 JBrowse link 5 67,292,901 67,306,208 RGD:9068941
G KPTN kaptin, actin binding protein JBrowse link 6 53,238,650 53,246,458 RGD:14298760
G RNF152 ring finger protein 152 JBrowse link 1 159,529,879 159,606,031 RGD:14298760
G SESN1 sestrin 1 JBrowse link 1 75,056,731 75,170,374 RGD:14298760
G SESN2 sestrin 2 JBrowse link 6 85,321,982 85,348,044 RGD:14298760
G SESN3 sestrin 3 JBrowse link 9 27,207,239 27,279,205 RGD:14298760
G STK11 serine/threonine kinase 11 JBrowse link 2 77,229,888 77,249,322 RGD:14298760
G SZT2 SZT2 subunit of KICSTOR complex JBrowse link 6 167,811,589 167,861,321 RGD:14298760
G TSC2 TSC complex subunit 2 JBrowse link 3 39,898,924 39,935,579 RGD:9068941
positive regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT3 AKT serine/threonine kinase 3 JBrowse link 10 16,441,465 16,741,745 RGD:9068941
G FLCN folliculin JBrowse link 12 61,029,186 61,045,400 RGD:9068941
G FNIP1 folliculin interacting protein 1 JBrowse link 2 133,958,112 134,093,408 RGD:14298760
G GAS6 growth arrest specific 6 JBrowse link 11 78,848,797 78,880,733 RGD:9068941
G HDAC3 histone deacetylase 3 JBrowse link 2 143,273,188 143,287,421 RGD:14298760
G HTR6 5-hydroxytryptamine receptor 6 JBrowse link 6 78,077,358 78,092,211 RGD:9068941
G KDR kinase insert domain receptor JBrowse link 8 41,809,116 41,856,379 RGD:9068941
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 JBrowse link 9 6,674,045 6,680,067 RGD:14298760
G LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 JBrowse link 4 93,972,112 93,975,561 RGD:14298760
G LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 JBrowse link 8 120,625,897 120,642,630 RGD:14298760
G LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 JBrowse link 3 8,119,338 8,171,790 RGD:14298760
G LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 4 109,722,664 109,728,278 RGD:14298760
G LARS1 leucyl-tRNA synthetase 1 JBrowse link 2 147,480,132 147,554,197 RGD:9068941
G LEP leptin JBrowse link 18 20,106,867 20,124,071 RGD:14298760
G LIN28A lin-28 homolog A JBrowse link 6 83,806,178 83,818,550 RGD:14298760
G LOC110257335 Golgi phosphoprotein 3 JBrowse link 16 18,367,264 18,416,496 RGD:9068941
G MIOS meiosis regulator for oocyte development JBrowse link 9 77,851,764 77,892,417 RGD:14298760
G MLST8 MTOR associated protein, LST8 homolog JBrowse link 3 39,778,746 39,786,206 RGD:14298760
G MYCBP MYC binding protein JBrowse link 6 94,805,649 94,814,443 RGD:14298760
G RELN reelin JBrowse link 9 103,460,855 103,963,728 RGD:14298760
G RHEB Ras homolog, mTORC1 binding JBrowse link 18 5,779,439 5,821,839 RGD:14298760
G RICTOR RPTOR independent companion of MTOR complex 2 JBrowse link 16 24,109,934 24,250,019 RGD:14298760
G RPTOR regulatory associated protein of MTOR complex 1 JBrowse link 12 1,709,121 1,991,844 RGD:14298760
G RRAGA Ras related GTP binding A JBrowse link 1 203,772,063 203,774,580 RGD:14298760
G RRAGB Ras related GTP binding B JBrowse link X 48,286,584 48,330,196 RGD:14298760
G RRAGC Ras related GTP binding C JBrowse link 6 94,785,906 94,803,017 RGD:14298760
G RRAGD Ras related GTP binding D JBrowse link 1 57,374,047 57,424,058 RGD:14298760
G SEC13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 13 66,483,620 66,524,411 RGD:9068941
G SLC38A9 solute carrier family 38 member 9 JBrowse link 16 34,639,575 34,858,827 RGD:14298760
G SMCR8 SMCR8-C9orf72 complex subunit JBrowse link 12 60,435,276 60,443,525 RGD:14298760
G TREM2 triggering receptor expressed on myeloid cells 2 JBrowse link 7 36,465,921 36,471,509 RGD:9068941
G WDR24 WD repeat domain 24 JBrowse link 3 41,085,415 41,090,628 RGD:14298760
G WDR59 WD repeat domain 59 JBrowse link 6 12,682,166 12,769,339 RGD:14298760
G XBP1 X-box binding protein 1 JBrowse link 14 46,011,239 46,016,526 RGD:9068941
positive regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEP192 centrosomal protein 192 JBrowse link 6 96,611,560 96,733,800 RGD:14298760
G CLEC16A C-type lectin domain containing 16A JBrowse link 3 31,938,133 32,158,343 RGD:9068941
G COPS3 COP9 signalosome subunit 3 JBrowse link 12 61,000,562 61,023,920 RGD:14298760
G GPR137 G protein-coupled receptor 137 JBrowse link 2 7,826,454 7,831,010 RGD:14298760
G GPR137B G protein-coupled receptor 137B JBrowse link 14 55,125,405 55,181,688 RGD:14298760
G GPR137C G protein-coupled receptor 137C JBrowse link 1 182,203,185 182,263,753 RGD:14298760
G KLHL22 kelch like family member 22 JBrowse link 14 50,773,917 50,809,991 RGD:14298760
G LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 4 109,722,664 109,728,278 RGD:14298760
G LARS1 leucyl-tRNA synthetase 1 JBrowse link 2 147,480,132 147,554,197 RGD:9068941
G PIH1D1 PIH1 domain containing 1 JBrowse link 6 54,524,172 54,529,700 RGD:14298760
G PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 JBrowse link 7 78,447,323 78,451,761 RGD:14298760
G RRAGA Ras related GTP binding A JBrowse link 1 203,772,063 203,774,580 RGD:14298760
G RRAGB Ras related GTP binding B JBrowse link X 48,286,584 48,330,196 RGD:14298760
G RRAGD Ras related GTP binding D JBrowse link 1 57,374,047 57,424,058 RGD:14298760
G SEC13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 13 66,483,620 66,524,411 RGD:14298760
G SIK3 SIK family kinase 3 JBrowse link 9 44,223,227 44,471,689 RGD:9068941
G TELO2 telomere maintenance 2 JBrowse link 3 40,372,215 40,386,777 RGD:14298760
positive regulation of TORC2 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SIK3 SIK family kinase 3 JBrowse link 9 44,223,227 44,471,689 RGD:9068941
G TELO2 telomere maintenance 2 JBrowse link 3 40,372,215 40,386,777 RGD:14298760
regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C10H9orf72 chromosome 10 C9orf72 homolog JBrowse link 10 38,389,366 38,415,903 RGD:14298760
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 14 47,261,905 47,266,729 RGD:14298760
G DGKQ diacylglycerol kinase theta JBrowse link 8 313,325 325,089 RGD:9068941
G DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 JBrowse link 9 67,268,600 67,279,617 RGD:14298760
G MYCBP MYC binding protein JBrowse link 6 94,805,649 94,814,443 RGD:14298760
G RRAGC Ras related GTP binding C JBrowse link 6 94,785,906 94,803,017 RGD:14298760
G SMCR8 SMCR8-C9orf72 complex subunit JBrowse link 12 60,435,276 60,443,525 RGD:14298760
regulation of TORC2 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PIH1D1 PIH1 domain containing 1 JBrowse link 6 54,524,172 54,529,700 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16411
    signaling 6414
      signal transduction 5871
        intracellular signal transduction 2465
          regulation of intracellular signal transduction 1620
            regulation of TOR signaling 102
              negative regulation of TOR signaling + 44
              positive regulation of TOR signaling + 45
              regulation of TORC1 signaling + 40
              regulation of TORC2 signaling + 3
Path 2
Term Annotations click to browse term
  biological_process 16411
    biological regulation 11882
      regulation of biological process 11314
        regulation of cellular process 10867
          signal transduction 5871
            regulation of signal transduction 2820
              regulation of intracellular signal transduction 1620
                regulation of TOR signaling 102
                  negative regulation of TOR signaling + 44
                  positive regulation of TOR signaling + 45
                  regulation of TORC1 signaling + 40
                  regulation of TORC2 signaling + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.