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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of TOR signaling
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Accession:GO:0032006 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of TOR signaling.
Synonyms:exact_synonym: regulation of TOR signaling pathway;   regulation of TOR signalling pathway;   regulation of target of rapamycin signaling pathway;   regulation of target of rapamycin signalling pathway
 related_synonym: regulation of TOR signaling cascade


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regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Araf A-Raf proto-oncogene, serine/threonine kinase JBrowse link X 1,369,534 1,391,603 RGD:1624291
RGD:1600115
G Ddit4 DNA-damage-inducible transcript 4 JBrowse link 20 29,509,283 29,511,382 RGD:13792537
G Fam83d family with sequence similarity 83, member D JBrowse link 3 155,269,344 155,288,612 RGD:1624291
RGD:13792537
G Fbxo9 f-box protein 9 JBrowse link 8 85,388,331 85,413,896 RGD:1624291
RGD:1600115
G Flcn folliculin JBrowse link 10 46,153,185 46,172,331 RGD:1624291
RGD:1600115
G Gba glucosylceramidase beta JBrowse link 2 188,511,781 188,522,602 RGD:1624291
G Gna12 G protein subunit alpha 12 JBrowse link 12 15,890,202 15,971,212 RGD:1624291
RGD:1600115
G Gpat3 glycerol-3-phosphate acyltransferase 3 JBrowse link 14 10,343,287 10,396,565 RGD:1624291
G Itfg2 integrin alpha FG-GAP repeat containing 2 JBrowse link 4 161,730,643 161,744,281 RGD:13792537
G Pkhd1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link 9 26,164,969 26,736,704 RGD:1624291
G RGD1565472 similar to RIKEN cDNA 2310003P10 JBrowse link 11 39,765,341 39,767,938 RGD:13792537
G Rheb Ras homolog, mTORC1 binding JBrowse link 4 6,827,429 6,873,384 RGD:1624291
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase JBrowse link 20 33,100,190 33,323,544 RGD:1624291
RGD:13792537
RGD:1600115
G RragB Ras-related GTP binding B JBrowse link X 19,085,913 19,135,049 RGD:1624291
G Rragc Ras-related GTP binding C JBrowse link 5 141,572,536 141,590,784 RGD:1624291
G Slc7a1 solute carrier family 7 member 1 JBrowse link 12 8,032,775 8,108,972 RGD:1642930
G Slc7a3 solute carrier family 7 member 3 JBrowse link X 70,972,767 70,979,466 RGD:1642930
G Tbck TBC1 domain containing kinase JBrowse link 2 237,751,646 237,958,497 RGD:1624291
G Telo2 telomere maintenance 2 JBrowse link 10 14,461,581 14,476,812 RGD:1624291
G Tmem127 transmembrane protein 127 JBrowse link 3 119,677,575 119,690,371 RGD:1624291
RGD:13792537
G Trem2 triggering receptor expressed on myeloid cells 2 JBrowse link 9 14,611,541 14,618,076 RGD:1624291
G Tti1 TELO2 interacting protein 1 JBrowse link 3 154,463,108 154,506,955 RGD:1624291
RGD:13792537
G Zmpste24 zinc metallopeptidase STE24 JBrowse link 5 139,982,404 140,015,541 RGD:1624291
negative regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07029605.1 RGD:1600115
G Akt1s1 AKT1 substrate 1 JBrowse link 1 100,845,443 100,851,961 RGD:1624291
RGD:13792537
G Arntl aryl hydrocarbon receptor nuclear translocator-like JBrowse link 1 178,039,002 178,137,469 RGD:1600115
RGD:1624291
G Cryba1 crystallin, beta A1 JBrowse link 10 65,160,777 65,167,504 RGD:10059647
G Ddit4 DNA-damage-inducible transcript 4 JBrowse link 20 29,509,283 29,511,382 RGD:1624291
RGD:13792537
RGD:1600115
RGD:8554300
G Depdc5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 14 83,089,000 83,219,576 RGD:1624291
RGD:13792537
G Deptor DEP domain containing MTOR-interacting protein JBrowse link 7 94,795,161 95,000,750 RGD:1624291
G Epm2a EPM2A glucan phosphatase, laforin JBrowse link 1 5,448,958 5,571,512 RGD:1624291
G Flcn folliculin JBrowse link 10 46,153,185 46,172,331 RGD:1600115
RGD:1624291
G Fnip1 folliculin interacting protein 1 JBrowse link 10 39,786,687 39,870,188 RGD:1624291
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 1 82,097,244 82,108,238 RGD:1624291
RGD:13792537
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:1624291
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Mapkapk5 MAPK activated protein kinase 5 JBrowse link 12 40,510,378 40,529,332 RGD:1624291
RGD:13792537
G Minar1 membrane integral NOTCH2 associated receptor 1 JBrowse link 8 96,970,556 97,008,687 RGD:1624291
RGD:13792537
RGD:13825189
G Mtm1 myotubularin 1 JBrowse link 6 18,821,821 18,840,449 RGD:1624291
G Nprl2 NPR2-like, GATOR1 complex subunit JBrowse link 8 116,297,950 116,301,123 RGD:1624291
RGD:13792537
G Nprl3 NPR3-like, GATOR1 complex subunit JBrowse link 10 15,620,824 15,661,332 RGD:1624291
RGD:13792537
G Pdcd6 programmed cell death 6 JBrowse link 1 31,576,183 31,591,852 RGD:1624291
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:1624291
RGD:1600115
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 5 124,568,845 124,642,569 RGD:1600115
RGD:1624291
G RGD1565472 similar to RIKEN cDNA 2310003P10 JBrowse link 11 39,765,341 39,767,938 RGD:1600115
G Sh3bp4 SH3-domain binding protein 4 JBrowse link 9 96,210,750 96,288,903 RGD:1600115
RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
RGD:1600115
G Tbc1d7 TBC1 domain family, member 7 JBrowse link 17 23,774,793 23,792,389 RGD:1624291
RGD:13792537
G Tmem127 transmembrane protein 127 JBrowse link 3 119,677,575 119,690,371 RGD:1624291
G Tnfaip8l1 TNF alpha induced protein 8 like 1 JBrowse link 9 10,894,949 10,905,647 RGD:1624291
RGD:13792537
RGD:1600115
G Tsc1 TSC complex subunit 1 JBrowse link 3 7,219,955 7,269,063 RGD:10448950
RGD:13792537
RGD:1624291
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:1580520
RGD:13792537
RGD:1624291
RGD:1600115
G Tsc2_v1 TSC complex subunit 2, variant 1 RGD:13792537
G Tsc2_v2 TSC complex subunit 2, variant 2 RGD:13792537
G Ubr1 ubiquitin protein ligase E3 component n-recognin 1 JBrowse link 3 112,800,557 112,910,038 RGD:1624291
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 JBrowse link 9 16,003,058 16,080,152 RGD:1624291
negative regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07029605.1 RGD:13792537
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
RGD:13792537
G Bmt2 base methyltransferase of 25S rRNA 2 homolog JBrowse link 4 40,064,131 40,136,074 RGD:1624291
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 14 84,447,552 84,457,396 RGD:1624291
RGD:13792537
RGD:1600115
G Castor2 cytosolic arginine sensor for mTORC1 subunit 2 JBrowse link 12 25,595,800 25,638,806 RGD:1624291
RGD:13792537
G Depdc5 DEP domain containing 5, GATOR1 subcomplex subunit JBrowse link 14 83,089,000 83,219,576 RGD:1624291
G Fnip2 folliculin interacting protein 2 JBrowse link 2 178,223,561 178,334,925 RGD:13792537
G Itfg2 integrin alpha FG-GAP repeat containing 2 JBrowse link 4 161,730,643 161,744,281 RGD:1624291
G Kptn kaptin (actin binding protein) JBrowse link 1 78,015,714 78,016,508 RGD:1624291
G Kptn kaptin RGD:13792537
G RGD1565498 similar to Hypothetical protein LOC270802 JBrowse link 7 63,922,871 63,937,721 RGD:1624291
RGD:13792537
G Rnf152 ring finger protein 152 JBrowse link 13 25,183,295 25,262,785 RGD:1624291
RGD:1600115
G Sesn1 sestrin 1 JBrowse link 20 46,667,116 46,758,306 RGD:1624291
RGD:13792537
G Sesn2 sestrin 2 JBrowse link 5 150,684,891 150,703,846 RGD:1624291
RGD:13792537
G Sesn3 sestrin 3 JBrowse link 8 12,823,060 12,878,749 RGD:1624291
RGD:13792537
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:1624291
RGD:1600115
G Szt2 SZT2 subunit of KICSTOR complex JBrowse link 5 137,192,120 137,238,384 RGD:1624291
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:1624291
positive regulation of TOR signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07029605.1 RGD:1600115
G Akt3 AKT serine/threonine kinase 3 JBrowse link 13 95,076,308 95,348,913 RGD:1624291
RGD:1600115
G Flcn folliculin JBrowse link 10 46,153,185 46,172,331 RGD:1624291
RGD:1600115
G Fnip1 folliculin interacting protein 1 JBrowse link 10 39,786,687 39,870,188 RGD:1624291
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:8554638
G Golph3 golgi phosphoprotein 3 JBrowse link 2 62,360,754 62,388,773 RGD:1600115
RGD:1624291
G Hdac3 histone deacetylase 3 JBrowse link 18 31,073,057 31,094,347 RGD:1600115
RGD:1624291
G Htr6 5-hydroxytryptamine receptor 6 JBrowse link 5 157,501,202 157,518,870 RGD:1624291
RGD:1600115
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:2292019
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 JBrowse link 1 166,991,474 166,997,045 RGD:1624291
RGD:1600115
G Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 JBrowse link 2 187,911,530 187,914,930 RGD:1624291
RGD:13792537
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 JBrowse link 2 243,160,821 243,173,057 RGD:1624291
RGD:13792537
RGD:1600115
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 JBrowse link 12 19,573,909 19,577,625 RGD:1624291
RGD:13792537
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 2 210,034,095 210,039,451 RGD:1624291
G Lars1 leucyl-tRNA synthetase 1 JBrowse link 18 36,524,013 36,579,471 RGD:1624291
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:1624291
RGD:13792537
RGD:1600115
G Lin28a lin-28 homolog A JBrowse link 5 152,230,343 152,247,873 RGD:1624291
G LOC100361543 RhoA activator C11orf59-like JBrowse link X 37,261,428 37,262,470 RGD:1600115
G LOC108348096 ras-related GTP-binding protein B JBrowse link X 19,336,382 19,369,872 RGD:1600115
RGD:13792537
G Mios meiosis regulator for oocyte development JBrowse link 4 34,238,370 34,264,015 RGD:1624291
RGD:13792537
G Mlst8 MTOR associated protein, LST8 homolog JBrowse link 10 13,839,250 13,845,001 RGD:1624291
RGD:1600115
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1624291
RGD:1600115
G Rheb Ras homolog, mTORC1 binding JBrowse link 4 6,827,429 6,873,384 RGD:1600115
RGD:1624291
G Rictor RPTOR independent companion of MTOR, complex 2 JBrowse link 2 56,013,898 56,105,818 RGD:1624291
G Rptor regulatory associated protein of MTOR, complex 1 JBrowse link 10 108,750,620 109,058,691 RGD:1624291
G Rraga Ras-related GTP binding A JBrowse link 5 104,941,067 104,942,662 RGD:13792537
G RragB Ras-related GTP binding B JBrowse link X 19,085,913 19,135,049 RGD:1624291
RGD:13792537
RGD:1600115
G Rragc Ras-related GTP binding C JBrowse link 5 141,572,536 141,590,784 RGD:13792537
G Rragd Ras-related GTP binding D JBrowse link 5 48,224,994 48,260,691 RGD:13792537
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 4 145,686,186 145,699,577 RGD:1624291
G Seh1l SEH1-like nucleoporin JBrowse link 18 63,545,150 63,568,101 RGD:1624291
G Slc38a9 solute carrier family 38, member 9 JBrowse link 2 44,512,556 44,592,793 RGD:1600115
RGD:1624291
G Smcr8 SMCR8-C9orf72 complex subunit JBrowse link 10 47,019,326 47,026,465 RGD:1624291
G Trem2 triggering receptor expressed on myeloid cells 2 JBrowse link 9 14,611,541 14,618,076 RGD:1624291
G Wdr24 WD repeat domain 24 JBrowse link 10 15,191,078 15,195,860 RGD:1624291
G Wdr59 WD repeat domain 59 JBrowse link 19 43,651,686 43,714,391 RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
positive regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07041481.1 RGD:1600115
G Clec16a C-type lectin domain containing 16A JBrowse link 10 5,002,196 5,196,914 RGD:1624291
G Flcn folliculin JBrowse link 10 46,153,185 46,172,331 RGD:13792537
G Gpr137 G protein-coupled receptor 137 JBrowse link 1 222,194,266 222,197,252 RGD:13792537
G Gpr137b G protein-coupled receptor 137B JBrowse link 17 90,670,852 90,709,003 RGD:1624291
RGD:13792537
G Gpr137c G protein-coupled receptor 137C JBrowse link 15 19,547,783 19,615,717 RGD:13792537
G Klhl22 kelch-like family member 22 JBrowse link 11 87,646,489 87,718,808 RGD:1600115
RGD:1624291
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 2 210,034,095 210,039,451 RGD:13792537
G Lars1 leucyl-tRNA synthetase 1 JBrowse link 18 36,524,013 36,579,471 RGD:1624291
G Pih1d1 PIH1 domain containing 1 JBrowse link 1 101,151,240 101,156,806 RGD:1624291
G Pip4p1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 JBrowse link 15 27,852,152 27,855,999 RGD:1624291
RGD:1600115
G Rraga Ras-related GTP binding A JBrowse link 5 104,941,067 104,942,662 RGD:1624291
RGD:1600115
G RragB Ras-related GTP binding B JBrowse link X 19,085,913 19,135,049 RGD:1624291
G Rragd Ras-related GTP binding D JBrowse link 5 48,224,994 48,260,691 RGD:1624291
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 4 145,686,186 145,699,577 RGD:1600115
G Seh1l SEH1-like nucleoporin JBrowse link 18 63,545,150 63,568,101 RGD:1624291
G Sik3 SIK family kinase 3 JBrowse link 8 50,310,263 50,520,284 RGD:1624291
G Telo2 telomere maintenance 2 JBrowse link 10 14,461,581 14,476,812 RGD:1624291
positive regulation of TORC2 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sik3 SIK family kinase 3 JBrowse link 8 50,310,263 50,520,284 RGD:1624291
G Telo2 telomere maintenance 2 JBrowse link 10 14,461,581 14,476,812 RGD:1624291
regulation of TORC1 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgkq diacylglycerol kinase, theta JBrowse link 14 2,069,409 2,083,370 RGD:1624291
G Dyrk3 dual specificity tyrosine phosphorylation regulated kinase 3 JBrowse link 13 47,906,230 47,916,877 RGD:1600115
RGD:1624291
G RGD1359108 similar to RIKEN cDNA 3110043O21 JBrowse link 5 50,666,444 50,691,523 RGD:1600115
RGD:1624291
G Rraga Ras-related GTP binding A JBrowse link 5 104,941,067 104,942,662 RGD:1600115
G Rragc Ras-related GTP binding C JBrowse link 5 141,572,536 141,590,784 RGD:1624291
G Smcr8 SMCR8-C9orf72 complex subunit JBrowse link 10 47,019,326 47,026,465 RGD:1624291
regulation of TORC2 signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pih1d1 PIH1 domain containing 1 JBrowse link 1 101,151,240 101,156,806 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    signaling 7553
      signal transduction 6968
        intracellular signal transduction 2597
          regulation of intracellular signal transduction 1695
            regulation of TOR signaling 108
              negative regulation of TOR signaling + 48
              positive regulation of TOR signaling + 47
              regulation of TORC1 signaling + 41
              regulation of TORC2 signaling + 3
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          signal transduction 6968
            regulation of signal transduction 2973
              regulation of intracellular signal transduction 1695
                regulation of TOR signaling 108
                  negative regulation of TOR signaling + 48
                  positive regulation of TOR signaling + 47
                  regulation of TORC1 signaling + 41
                  regulation of TORC2 signaling + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.