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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of insulin secretion
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Accession:GO:0032024 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
Synonyms:exact_synonym: up regulation of insulin secretion;   upregulation of insulin secretion
 narrow_synonym: activation of insulin secretion;   stimulation of insulin secretion


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positive regulation of insulin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aacs acetoacetyl-CoA synthetase JBrowse link 12 36,512,393 36,555,694 RGD:2301019
G Abat 4-aminobutyrate aminotransferase JBrowse link 10 7,093,406 7,200,439 RGD:9588550
G Acsl4 acyl-CoA synthetase long-chain family member 4 JBrowse link X 113,596,247 113,660,024 RGD:14695075
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:1624291
RGD:1600115
G Blk BLK proto-oncogene, Src family tyrosine kinase JBrowse link 15 46,555,552 46,593,778 RGD:1624291
RGD:1600115
G Capn10 calpain 10 JBrowse link 9 100,104,000 100,112,833 RGD:1624291
RGD:1600115
G Cask calcium/calmodulin dependent serine protein kinase JBrowse link X 9,815,652 10,156,155 RGD:11576293
G Casr calcium-sensing receptor JBrowse link 11 67,188,204 67,262,261 RGD:7205453
G Cd38 CD38 molecule JBrowse link 14 71,714,768 71,754,990 RGD:2307276
G Doc2b double C2 domain beta JBrowse link 10 63,921,255 63,952,944 RGD:1600115
RGD:1624291
G Ffar1 free fatty acid receptor 1 JBrowse link 1 89,308,475 89,309,379 RGD:2315053
RGD:1600115
RGD:1624291
G Gck glucokinase JBrowse link 14 86,149,146 86,191,589 RGD:1581879
RGD:1600115
RGD:1624291
RGD:2301916
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:8554453
G Gip gastric inhibitory polypeptide JBrowse link 10 83,835,080 83,848,399 RGD:2312537
G Gipr gastric inhibitory polypeptide receptor JBrowse link 1 80,063,047 80,073,223 RGD:2312607
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:8662441
G Glp1r glucagon-like peptide 1 receptor JBrowse link 20 9,586,075 9,626,228 RGD:625448
G Glrx glutaredoxin JBrowse link 2 2,606,032 2,615,944 RGD:9686053
G Glud1 glutamate dehydrogenase 1 JBrowse link 16 10,661,486 10,695,557 RGD:1624291
RGD:1600115
G Glul glutamate-ammonia ligase JBrowse link 13 71,331,052 71,340,207 RGD:2301557
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 12 17,309,122 17,315,267 RGD:1600115
RGD:1624291
G Gpr39 G protein-coupled receptor 39 JBrowse link 13 42,008,642 42,220,737 RGD:1624291
G Gpr68 G protein-coupled receptor 68 JBrowse link 6 124,874,151 124,903,949 RGD:1624291
G Irs2 insulin receptor substrate 2 JBrowse link 16 83,824,515 83,848,569 RGD:1624291
RGD:1600115
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:729103
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1641815
G Mcu mitochondrial calcium uniporter JBrowse link 20 29,037,452 29,199,224 RGD:1624291
RGD:1600115
G Myrip myosin VIIA and Rab interacting protein JBrowse link 8 128,972,307 129,139,257 RGD:8554303
G Nkx6-1 NK6 homeobox 1 JBrowse link 14 9,555,264 9,562,197 RGD:2306242
G Nlgn2 neuroligin 2 JBrowse link 10 56,431,586 56,444,847 RGD:9743981
RGD:1600115
RGD:1624291
RGD:2314456
G Nnat neuronatin JBrowse link 3 154,043,873 154,046,334 RGD:1624291
RGD:13792537
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 JBrowse link 5 151,776,004 151,779,319 RGD:2311606
G Oga O-GlcNAcase JBrowse link 1 265,506,752 265,542,452 RGD:2305956
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) JBrowse link 15 34,216,735 34,224,357 RGD:7242950
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:2306975
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 JBrowse link 13 47,413,453 47,440,682 RGD:2304071
G Pfkm phosphofructokinase, muscle JBrowse link 7 139,702,066 139,722,132 RGD:1624291
RGD:1600115
G Ppard peroxisome proliferator-activated receptor delta JBrowse link 20 7,818,289 7,883,482 RGD:2324877
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:1624291
G Psmd9 proteasome 26S subunit, non-ATPase 9 JBrowse link 12 38,786,539 38,805,121 RGD:633869
G Ptbp1 polypyrimidine tract binding protein 1 JBrowse link 7 12,663,965 12,673,723 RGD:10045958
G Rbp4 retinol binding protein 4 JBrowse link 1 256,806,476 256,813,678 RGD:1624291
RGD:1600115
G Rph3al rabphilin 3A-like (without C2 domains) JBrowse link 10 63,989,556 64,140,584 RGD:1600115
RGD:1624291
G Serp1 stress-associated endoplasmic reticulum protein 1 JBrowse link 2 148,718,279 148,722,263 RGD:1624291
RGD:1600115
G Sirt3 sirtuin 3 JBrowse link 1 213,613,502 213,636,061 RGD:9586042
G Slc30a8 solute carrier family 30 member 8 JBrowse link 7 91,832,988 91,869,329 RGD:2315022
G Snap25 synaptosome associated protein 25 JBrowse link 3 129,697,408 129,788,417 RGD:1581081
G Sox4 SRY-box transcription factor 4 JBrowse link 17 37,615,022 37,619,728 RGD:1624291
G Tardbp TAR DNA binding protein JBrowse link 5 165,432,089 165,442,232 RGD:7243008
G Tcf7l2 transcription factor 7 like 2 JBrowse link 1 276,686,911 276,730,517 RGD:1624291
RGD:13792537
G Tm7sf3 transmembrane 7 superfamily member 3 JBrowse link 4 180,913,703 180,951,564 RGD:1624291
RGD:1600115
G Trh thyrotropin releasing hormone JBrowse link 4 124,110,716 124,113,242 RGD:1600419
RGD:13792537
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 JBrowse link 20 11,434,062 11,482,880 RGD:9999436
G Ucn3 urocortin 3 JBrowse link 17 69,959,879 69,966,532 RGD:2306172
positive regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy8 adenylate cyclase 8 JBrowse link 7 105,353,883 105,593,372 RGD:1600115
RGD:1624291
RGD:8553299
G Ano1 anoctamin 1 JBrowse link 1 217,754,349 217,902,540 RGD:1624291
RGD:1600115
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
RGD:1600115
G Atg7 autophagy related 7 JBrowse link 4 146,570,113 146,777,093 RGD:1624291
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:1624291
RGD:1600115
G Baiap3 BAI1-associated protein 3 JBrowse link 10 14,601,133 14,613,881 RGD:1624291
RGD:1600115
G C1qtnf12 C1q and TNF related 12 JBrowse link 5 173,390,901 173,395,276 RGD:1624291
RGD:1600115
G C2cd2l C2CD2-like JBrowse link 8 48,641,792 48,652,119 RGD:1624291
RGD:1600115
G Cacna1d calcium voltage-gated channel subunit alpha1 D JBrowse link 16 6,110,294 6,405,022 RGD:13506727
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:1600115
RGD:1624291
G Cltrn collectrin, amino acid transport regulator JBrowse link X 32,118,082 32,153,687 RGD:1624291
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:5508172
G Dynll1 dynein light chain LC8-type 1 JBrowse link 12 47,074,200 47,076,573 RGD:1642149
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:1600115
RGD:13792537
RGD:1624291
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:12905046
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:1624291
RGD:1600115
G Gpr27 G protein-coupled receptor 27 JBrowse link 4 132,137,793 132,138,926 RGD:1624291
RGD:1600115
G Gpr39 G protein-coupled receptor 39 JBrowse link 13 42,008,642 42,220,737 RGD:1624291
G Gpr68 G protein-coupled receptor 68 JBrowse link 6 124,874,151 124,903,949 RGD:1624291
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Kif5b kinesin family member 5B JBrowse link 17 54,181,416 54,219,048 RGD:11059539
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:10412039
G Lrp1 LDL receptor related protein 1 JBrowse link 7 70,846,313 70,927,028 RGD:13800516
G Mpc2 mitochondrial pyruvate carrier 2 JBrowse link 13 83,680,527 83,700,491 RGD:1624291
RGD:1600115
G Myh9 myosin, heavy chain 9 JBrowse link 7 118,740,005 118,792,507 RGD:12798521
G Nadk NAD kinase JBrowse link 5 172,984,930 173,015,505 RGD:13703105
G Ncoa6 nuclear receptor coactivator 6 JBrowse link 3 150,919,317 150,990,391 RGD:9590126
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:1600115
RGD:1624291
G Oxct1 3-oxoacid CoA transferase 1 JBrowse link 2 53,859,738 54,007,733 RGD:2326185
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:1624291
RGD:1600115
G Phpt1 phosphohistidine phosphatase 1 JBrowse link 3 2,797,037 2,798,436 RGD:8554604
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:6482760
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link 15 4,209,702 4,236,895 RGD:8553382
RGD:1624291
RGD:1600115
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:10413842
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:14392803
G Rfx6 regulatory factor X, 6 JBrowse link 20 32,709,282 32,764,040 RGD:1624291
RGD:1600115
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:9585658
G Sri sorcin JBrowse link 4 23,004,657 23,029,233 RGD:1624291
RGD:1600115
G Stx4 syntaxin 4 JBrowse link 1 199,287,384 199,295,606 RGD:1600115
RGD:1624291
G Sybu syntabulin JBrowse link 7 83,600,614 83,670,121 RGD:8554225
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 JBrowse link 5 3,783,247 3,836,485 RGD:10043784
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:10003029
G Vsnl1 visinin-like 1 JBrowse link 6 37,001,360 37,121,969 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18179
    positive regulation of biological process 6238
      positive regulation of transport 1146
        positive regulation of protein transport 469
          positive regulation of protein secretion 324
            positive regulation of insulin secretion 93
              positive regulation of insulin secretion involved in cellular response to glucose stimulus 44
Path 2
Term Annotations click to browse term
  biological_process 18179
    localization 6078
      establishment of localization 4667
        transport 4529
          nitrogen compound transport 2188
            amide transport 1869
              peptide transport 1836
                peptide secretion 687
                  regulation of peptide secretion 563
                    positive regulation of peptide secretion 357
                      positive regulation of protein secretion 324
                        positive regulation of insulin secretion 93
                          positive regulation of insulin secretion involved in cellular response to glucose stimulus 44
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.