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ONTOLOGY REPORT - ANNOTATIONS


Term:mitochondrial DNA metabolic process
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Accession:GO:0032042 term browser browse the term
Definition:The chemical reactions and pathways involving mitochondrial DNA.
Synonyms:exact_synonym: mitochondrial DNA metabolism;   mtDNA metabolic process;   mtDNA metabolism


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mitochondrial DNA metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LONP1 lon peptidase 1, mitochondrial JBrowse link 19 5,691,834 5,720,452 RGD:2290271
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:2290271
G POLG2 DNA polymerase gamma 2, accessory subunit JBrowse link 17 64,477,785 64,497,054 RGD:2290271
G SESN2 sestrin 2 JBrowse link 1 28,259,452 28,282,491 RGD:2290271
G TK2 thymidine kinase 2 JBrowse link 16 66,508,003 66,550,412 RGD:9068941
G TOP3A DNA topoisomerase III alpha JBrowse link 17 18,269,958 18,314,996 RGD:2290271
mitochondrial DNA repair term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 JBrowse link 3 14,112,077 14,124,870 RGD:9068941
G DNA2 DNA replication helicase/nuclease 2 JBrowse link 10 68,414,064 68,472,521 RGD:2290271
G LIG3 DNA ligase 3 JBrowse link 17 34,980,498 35,009,743 RGD:2290271
G MGME1 mitochondrial genome maintenance exonuclease 1 JBrowse link 20 17,968,594 17,991,122 RGD:2290271
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:2290271
G PRIMPOL primase and DNA directed polymerase JBrowse link 4 184,649,672 184,694,952 RGD:2290271
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:2290271
negative regulation of mitochondrial DNA metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FLCN folliculin JBrowse link 17 17,206,946 17,237,188 RGD:2290271
positive regulation of mitochondrial DNA metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PPARGC1A PPARG coactivator 1 alpha JBrowse link 4 23,792,021 24,472,905 RGD:2290271
regulation of mitochondrial DNA metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MPV17 mitochondrial inner membrane protein MPV17 JBrowse link 2 27,309,492 27,323,097 RGD:2290271
G STOX1 storkhead box 1 JBrowse link 10 68,827,531 68,895,942 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18542
    cellular process 17553
      cellular metabolic process 11192
        cellular macromolecule metabolic process 8680
          DNA metabolic process 1013
            mitochondrial DNA metabolic process 16
              DNA synthesis involved in mitochondrial DNA replication 0
              mitochondrial DNA catabolic process 0
              mitochondrial DNA repair 7
              mitochondrion DNA recombination 0
              negative regulation of mitochondrial DNA metabolic process 1
              positive regulation of mitochondrial DNA metabolic process 1
              regulation of mitochondrial DNA metabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 18542
    cellular process 17553
      cellular component organization or biogenesis 7086
        cellular component organization 6895
          organelle organization 4295
            mitochondrion organization 601
              mitochondrial genome maintenance 26
                mitochondrial DNA metabolic process 16
                  DNA synthesis involved in mitochondrial DNA replication 0
                  mitochondrial DNA catabolic process 0
                  mitochondrial DNA repair 7
                  mitochondrion DNA recombination 0
                  negative regulation of mitochondrial DNA metabolic process 1
                  positive regulation of mitochondrial DNA metabolic process 1
                  regulation of mitochondrial DNA metabolic process + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.