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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of nuclease activity
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Accession:GO:0032075 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
Synonyms:exact_synonym: up regulation of nuclease activity;   upregulation of nuclease activity
 narrow_synonym: activation of nuclease activity;   stimulation of nuclease activity
 related_synonym: nuclease activator


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positive regulation of nuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB2 high mobility group box 2 ISO (PMID:978439) UniProtKB PMID:978439 NCBI chr 4:165,559,848...165,562,625
Ensembl chr 4:177,797,457...177,800,952
JBrowse link
positive regulation of deoxyribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCNA proliferating cell nuclear antigen ISO (PMID:19443450) UniProtKB PMID:19443450 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440
JBrowse link
positive regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO (PMID:20605787) UniProtKB PMID:20605787 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G DDX11 DEAD/H-box helicase 11 ISO (PMID:18499658) UniProtKB PMID:18499658 NCBI chr12:55,176,165...55,207,123 JBrowse link
G PRKCD protein kinase C delta ISO (PMID:19059439) UniProtKB PMID:19059439 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G RPS3 ribosomal protein S3 ISO (PMID:18973764) UniProtKB PMID:18973764 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982
JBrowse link
positive regulation of endoribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA1A heat shock protein family A (Hsp70) member 1A ISO (PMID:20625543) ParkinsonsUK-UCL PMID:20625543 NCBI chr 6:31,476,710...31,491,411 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12567
    metabolic process 7893
      regulation of metabolic process 5176
        regulation of macromolecule metabolic process 4725
          regulation of nuclease activity 19
            positive regulation of nuclease activity 7
              positive regulation of deoxyribonuclease activity + 5
              positive regulation of endoribonuclease activity 1
              positive regulation of exonuclease activity + 0
Path 2
Term Annotations click to browse term
  biological_process 12567
    metabolic process 7893
      cellular metabolic process 7226
        cellular aromatic compound metabolic process 3854
          nucleobase-containing compound metabolic process 3689
            regulation of nucleobase-containing compound metabolic process 2816
              positive regulation of nucleobase-containing compound metabolic process 1678
                positive regulation of nuclease activity 7
                  positive regulation of deoxyribonuclease activity + 5
                  positive regulation of endoribonuclease activity 1
                  positive regulation of exonuclease activity + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.