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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of nuclease activity
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Accession:GO:0032075 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
Synonyms:exact_synonym: up regulation of nuclease activity;   upregulation of nuclease activity
 narrow_synonym: activation of nuclease activity;   stimulation of nuclease activity
 related_synonym: nuclease activator


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positive regulation of nuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB2 high mobility group box 2 IEA Ensembl GO_REF:0000107 NCBI chr25:23,939,024...23,941,720
Ensembl chr25:23,939,027...23,941,606
JBrowse link
positive regulation of deoxyribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCNA proliferating cell nuclear antigen IEA Ensembl GO_REF:0000107 NCBI chr24:16,478,774...16,485,992
Ensembl chr24:16,478,769...16,484,992
JBrowse link
positive regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G DDX11 DEAD/H-box helicase 11 IEA Ensembl GO_REF:0000107 NCBI chr27:42,067,845...42,102,699
Ensembl chr27:42,067,898...42,105,870
JBrowse link
G PRKCD protein kinase C delta IEA Ensembl GO_REF:0000107 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191
JBrowse link
G RPS3 ribosomal protein S3 ISO (PMID:18973764) UniProtKB PMID:18973764 NCBI chr21:23,180,515...23,187,034
Ensembl chr21:23,180,515...23,187,034
JBrowse link
positive regulation of endoribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSP70 heat shock protein 70 ISO (PMID:20625543) ParkinsonsUK-UCL PMID:20625543 NCBI chr12:1,285,282...1,287,670 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16190
    metabolic process 10657
      regulation of metabolic process 6410
        regulation of macromolecule metabolic process 5943
          regulation of nuclease activity 23
            positive regulation of nuclease activity 7
              positive regulation of deoxyribonuclease activity + 5
              positive regulation of endoribonuclease activity 1
              positive regulation of exonuclease activity + 0
Path 2
Term Annotations click to browse term
  biological_process 16190
    metabolic process 10657
      cellular metabolic process 9645
        cellular aromatic compound metabolic process 5107
          nucleobase-containing compound metabolic process 4916
            regulation of nucleobase-containing compound metabolic process 3537
              positive regulation of nucleobase-containing compound metabolic process 1907
                positive regulation of nuclease activity 7
                  positive regulation of deoxyribonuclease activity + 5
                  positive regulation of endoribonuclease activity 1
                  positive regulation of exonuclease activity + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.