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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of nuclease activity
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Accession:GO:0032075 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
Synonyms:exact_synonym: up regulation of nuclease activity;   upregulation of nuclease activity
 narrow_synonym: activation of nuclease activity;   stimulation of nuclease activity
 related_synonym: nuclease activator


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positive regulation of nuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB2 high mobility group box 2 IDA (PMID:978439) UniProtKB PMID:978439 NCBI chr 4:173,331,376...173,334,358
Ensembl chr 4:173,331,376...173,334,432
JBrowse link
positive regulation of deoxyribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCNA proliferating cell nuclear antigen IDA (PMID:19443450) UniProtKB PMID:19443450 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
positive regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 IDA (PMID:20605787) UniProtKB PMID:20605787 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G DDX11 DEAD/H-box helicase 11 IDA (PMID:18499658) UniProtKB PMID:18499658 NCBI chr12:31,073,860...31,104,799
Ensembl chr12:31,073,860...31,104,799
JBrowse link
G PRKCD protein kinase C delta IMP (PMID:19059439) UniProtKB PMID:19059439 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
JBrowse link
G RPS3 ribosomal protein S3 IDA (PMID:18973764) UniProtKB PMID:18973764 NCBI chr11:75,399,518...75,422,302
Ensembl chr11:75,399,515...75,422,280
JBrowse link
positive regulation of endoribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA1A heat shock protein family A (Hsp70) member 1A IDA (PMID:20625543) ParkinsonsUK-UCL PMID:20625543 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B IDA (PMID:20625543) ParkinsonsUK-UCL PMID:20625543 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
positive regulation of exoribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TCEA1 transcription elongation factor A1 IEA Ensembl GO_REF:0000107 NCBI chr 8:53,966,556...54,022,448
Ensembl chr 8:53,966,552...54,022,456
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18672
    metabolic process 12302
      regulation of metabolic process 7546
        regulation of macromolecule metabolic process 6987
          regulation of nuclease activity 23
            positive regulation of nuclease activity 9
              positive regulation of deoxyribonuclease activity + 5
              positive regulation of endoribonuclease activity 2
              positive regulation of exonuclease activity + 1
Path 2
Term Annotations click to browse term
  biological_process 18672
    metabolic process 12302
      cellular metabolic process 11278
        cellular aromatic compound metabolic process 6222
          nucleobase-containing compound metabolic process 5984
            regulation of nucleobase-containing compound metabolic process 4292
              positive regulation of nucleobase-containing compound metabolic process 2087
                positive regulation of nuclease activity 9
                  positive regulation of deoxyribonuclease activity + 5
                  positive regulation of endoribonuclease activity 2
                  positive regulation of exonuclease activity + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.