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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of nuclease activity
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Accession:GO:0032075 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
Synonyms:exact_synonym: up regulation of nuclease activity;   upregulation of nuclease activity
 narrow_synonym: activation of nuclease activity;   stimulation of nuclease activity
 related_synonym: nuclease activator


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positive regulation of nuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb2 high mobility group box 2 ISO (PMID:978439) UniProtKB PMID:978439 NCBI chrNW_004936516:4,536,664...4,539,331 JBrowse link
positive regulation of deoxyribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcna proliferating cell nuclear antigen ISO (PMID:19443450) UniProtKB PMID:19443450 NCBI chrNW_004936485:13,766,221...13,771,215 JBrowse link
positive regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO (PMID:20605787) UniProtKB PMID:20605787 NCBI chrNW_004936621:620,163...639,115 JBrowse link
G Ddx11 DEAD/H-box helicase 11 ISO (PMID:18499658) UniProtKB PMID:18499658 NCBI chrNW_004936606:181,457...209,286 JBrowse link
G Prkcd protein kinase C delta ISO (PMID:19059439) UniProtKB PMID:19059439 NCBI chrNW_004936473:3,892,625...3,923,467 JBrowse link
G Rps3 ribosomal protein S3 ISO (PMID:18973764) UniProtKB PMID:18973764 NCBI chrNW_004936498:4,198,189...4,204,531 JBrowse link
positive regulation of endoribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO (PMID:20625543) ParkinsonsUK-UCL PMID:20625543 NCBI chrNW_004936727:1,732,323...1,735,128 JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO (PMID:20625543) ParkinsonsUK-UCL PMID:20625543 NCBI chrNW_004936727:1,718,952...1,721,691 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12002
    metabolic process 7668
      regulation of metabolic process 5080
        regulation of macromolecule metabolic process 4667
          regulation of nuclease activity 18
            positive regulation of nuclease activity 8
              positive regulation of deoxyribonuclease activity + 5
              positive regulation of endoribonuclease activity 2
              positive regulation of exonuclease activity + 0
Path 2
Term Annotations click to browse term
  biological_process 12002
    metabolic process 7668
      cellular metabolic process 7071
        cellular aromatic compound metabolic process 3747
          nucleobase-containing compound metabolic process 3586
            regulation of nucleobase-containing compound metabolic process 2742
              positive regulation of nucleobase-containing compound metabolic process 1654
                positive regulation of nuclease activity 8
                  positive regulation of deoxyribonuclease activity + 5
                  positive regulation of endoribonuclease activity 2
                  positive regulation of exonuclease activity + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.