ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of NF-kappaB transcription factor activity
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Accession:GO:0032088 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
Synonyms:exact_synonym: inhibition of NF-kappaB transcription factor
 related_synonym: NF-kappaB inhibitor


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negative regulation of NF-kappaB transcription factor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acod1 aconitate decarboxylase 1 JBrowse link 15 93,612,968 93,622,322 RGD:1624291
G Adora3 adenosine A3 receptor JBrowse link 2 208,336,909 208,379,217 RGD:1624291
G Aim2 absent in melanoma 2 JBrowse link 13 91,919,834 91,963,080 RGD:1624291
RGD:1600115
G Anxa4 annexin A4 JBrowse link 4 118,538,775 118,595,591 RGD:1624291
RGD:1600115
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
RGD:1600115
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:1624291
RGD:1600115
G Brms1 BRMS1, transcriptional repressor and anoikis regulator JBrowse link 1 220,325,352 220,334,616 RGD:1624291
RGD:1600115
G Cactin cactin, spliceosome C complex subunit JBrowse link 7 11,258,526 11,266,509 RGD:1624291
RGD:1600115
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:1624291
RGD:1600115
G Cd200 Cd200 molecule JBrowse link 11 60,371,617 60,398,450 RGD:1600115
RGD:1624291
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 JBrowse link 10 84,780,644 84,789,800 RGD:1600115
RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Chp1 calcineurin-like EF-hand protein 1 JBrowse link 3 111,354,506 111,389,998 RGD:1624291
RGD:1600115
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:1624291
RGD:1600115
G Cmklr1 chemerin chemokine-like receptor 1 JBrowse link 12 48,743,556 48,796,582 RGD:1624291
RGD:1600115
G Commd1 copper metabolism domain containing 1 JBrowse link 14 107,664,321 107,759,974 RGD:1624291
RGD:1600115
G Commd6 COMM domain containing 6 JBrowse link 15 86,136,096 86,142,672 RGD:1624291
RGD:13792537
G Commd7 COMM domain containing 7 JBrowse link 3 149,101,242 149,115,227 RGD:1624291
RGD:13792537
G Cyld CYLD lysine 63 deubiquitinase JBrowse link 19 19,264,984 19,323,817 RGD:1600115
RGD:13792537
RGD:1624291
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:1600115
RGD:1624291
G Dab2ip DAB2 interacting protein JBrowse link 3 14,889,263 15,060,286 RGD:1624291
RGD:1600115
G Dap death-associated protein JBrowse link 2 84,275,884 84,328,998 RGD:1624291
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 JBrowse link 10 11,059,701 11,085,186 RGD:1624291
G Erbin erbb2 interacting protein JBrowse link 2 33,880,860 33,952,806 RGD:1624291
RGD:1600115
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
RGD:1600115
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:1624291
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
RGD:1600115
G Irak1 interleukin-1 receptor-associated kinase 1 JBrowse link X 156,716,469 156,726,367 RGD:1624291
RGD:1600115
G Irak2 interleukin-1 receptor-associated kinase 2 JBrowse link 4 145,594,575 145,651,066 RGD:1624291
RGD:1600115
G Irak3 interleukin-1 receptor-associated kinase 3 JBrowse link 7 64,922,830 64,982,224 RGD:1624291
RGD:1600115
G Itch itchy E3 ubiquitin protein ligase JBrowse link 3 150,660,665 150,752,016 RGD:1624291
RGD:1600115
G Klf4 Kruppel like factor 4 JBrowse link 5 72,283,311 72,287,669 RGD:1624291
RGD:1600115
G LOC108348098 breast cancer metastasis-suppressor 1 homolog JBrowse link 1 220,418,455 220,427,785 RGD:1600115
G Lrrc14 leucine rich repeat containing 14 JBrowse link 7 117,773,219 117,779,555 RGD:1600115
RGD:13792537
RGD:1624291
G Map2k5 mitogen activated protein kinase kinase 5 JBrowse link 8 68,055,976 68,282,656 RGD:8553940
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:1624291
G Nfkbid NFKB inhibitor delta JBrowse link 1 88,883,816 88,892,543 RGD:1624291
RGD:1600115
G Nfkbil1 NFKB inhibitor like 1 JBrowse link 20 4,823,590 4,839,202 RGD:1624291
RGD:1600115
G Nlrc3 NLR family, CARD domain containing 3 JBrowse link 10 11,809,531 11,844,184 RGD:1624291
RGD:1600115
G Nlrc5 NLR family, CARD domain containing 5 JBrowse link 19 10,904,381 11,006,202 RGD:1624291
RGD:1600115
G Nlrp12 NLR family, pyrin domain containing 12 JBrowse link 1 64,506,750 64,543,908 RGD:1624291
RGD:1600115
G Nlrp1b NLR family, pyrin domain containing 1B JBrowse link 10 57,755,957 57,847,867 RGD:1624291
G Nlrp2 NLR family pyrin domain containing 2 JBrowse link 1 73,082,648 73,121,118 RGD:1624291
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:1624291
RGD:1600115
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:1600115
RGD:1624291
G Nwd1 NACHT and WD repeat domain containing 1 JBrowse link 16 18,875,768 18,944,775 RGD:1624291
G Otulin OTU deubiquitinase with linear linkage specificity JBrowse link 2 80,267,724 80,293,204 RGD:1624291
RGD:13792537
G Parp10 poly (ADP-ribose) polymerase family, member 10 JBrowse link 7 117,291,592 117,300,878 RGD:1624291
G Peli1 pellino E3 ubiquitin protein ligase 1 JBrowse link 14 106,008,086 106,062,566 RGD:1624291
RGD:1600115
G Pias4 protein inhibitor of activated STAT, 4 JBrowse link 7 11,414,565 11,428,090 RGD:1624291
RGD:1600115
G Pkhd1 PKHD1, fibrocystin/polyductin JBrowse link 9 26,164,969 26,736,704 RGD:1624291
G Prdx2 peroxiredoxin 2 JBrowse link 19 26,084,816 26,090,095 RGD:1624291
RGD:1600115
G Prmt2 protein arginine methyltransferase 2 JBrowse link 20 13,154,513 13,212,613 RGD:1624291
RGD:1600115
G Psmd10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 112,323,188 112,328,642 RGD:1624291
RGD:1600115
G Ptgis prostaglandin I2 synthase JBrowse link 3 163,950,746 163,986,129 RGD:1624291
RGD:1600115
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
RGD:1600115
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 JBrowse link 3 147,793,014 147,809,941 RGD:1600115
RGD:1624291
G Rwdd3 RWD domain containing 3 JBrowse link 2 224,710,351 224,723,136 RGD:1624291
RGD:1600115
G Setd6 SET domain containing 6, protein lysine methyltransferase JBrowse link 19 9,758,613 9,766,333 RGD:1624291
RGD:13792537
RGD:1600115
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
G Siva1 SIVA1, apoptosis-inducing factor JBrowse link 6 137,209,999 137,214,379 RGD:1624291
G Tax1bp1 Tax1 binding protein 1 JBrowse link 4 82,776,720 82,832,586 RGD:1624291
RGD:1600115
G Tceal7 transcription elongation factor A like 7 JBrowse link X 106,774,954 106,777,072 RGD:1624291
RGD:1600115
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
G Tmigd3 transmembrane and immunoglobulin domain containing 3 JBrowse link 2 208,478,373 208,557,356 RGD:1624291
G Tmsb4x thymosin beta 4, X-linked JBrowse link X 28,593,405 28,617,267 RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
RGD:1600115
G Traf3 Tnf receptor-associated factor 3 JBrowse link 6 135,610,698 135,720,247 RGD:1624291
RGD:13792537
G Traip TRAF-interacting protein JBrowse link 8 116,730,170 116,750,528 RGD:1624291
RGD:1600115
G Trim21 tripartite motif-containing 21 JBrowse link 1 167,686,148 167,708,735 RGD:1624291
RGD:1600115
G Trim37 tripartite motif-containing 37 JBrowse link 10 74,436,165 74,568,636 RGD:1624291
RGD:1600115
G Trim40 tripartite motif-containing 40 JBrowse link 20 2,169,674 2,178,477 RGD:8553878
RGD:1624291
G Tut4 terminal uridylyl transferase 4 JBrowse link 5 128,063,880 128,168,726 RGD:1624291
RGD:1600115
G Ufl1 Ufm1-specific ligase 1 JBrowse link 5 39,616,479 39,650,894 RGD:1600115
RGD:1624291
G Usp7 ubiquitin specific peptidase 7 JBrowse link 10 6,930,462 7,019,910 RGD:1600115
RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115
cytoplasmic sequestering of NF-kappaB term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccdc22 coiled-coil domain containing 22 JBrowse link X 15,742,978 15,754,925 RGD:1624291
RGD:1600115
G Faf1 Fas associated factor 1 JBrowse link 5 129,370,767 129,738,393 RGD:1600115
RGD:1624291
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:2298880
RGD:1624291
RGD:2298917
RGD:2298882
RGD:2298908
G Nfkbib NFKB inhibitor beta JBrowse link 1 86,941,073 86,948,845 RGD:2298908
RGD:2298917
G Psmd10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 112,323,188 112,328,642 RGD:1624291
RGD:1600115
G Tmsb4x thymosin beta 4, X-linked JBrowse link X 28,593,405 28,617,267 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17928
    negative regulation of biological process 5361
      negative regulation of DNA-binding transcription factor activity 165
        negative regulation of NF-kappaB transcription factor activity 81
          cytoplasmic sequestering of NF-kappaB 6
Path 2
Term Annotations click to browse term
  biological_process 17928
    metabolic process 10678
      cellular metabolic process 9773
        cellular aromatic compound metabolic process 5091
          nucleobase-containing compound metabolic process 4884
            nucleic acid metabolic process 4438
              RNA metabolic process 3968
                RNA biosynthetic process 3114
                  nucleic acid-templated transcription 3097
                    transcription, DNA-templated 3053
                      regulation of transcription, DNA-templated 2948
                        regulation of DNA-binding transcription factor activity 414
                          negative regulation of DNA-binding transcription factor activity 165
                            negative regulation of NF-kappaB transcription factor activity 81
                              cytoplasmic sequestering of NF-kappaB 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.