ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of telomere maintenance
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Accession:GO:0032204 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.


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regulation of telomere maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hdac8 histone deacetylase 8 JBrowse link X 72,163,777 72,370,058 RGD:1624291
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 14 11,256,163 11,274,684 RGD:1624291
G Lmna lamin A/C JBrowse link 2 187,842,884 187,863,552 RGD:1624291
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:1624291
RGD:1600115
G Pif1 PIF1 5'-to-3' DNA helicase JBrowse link 8 71,124,477 71,133,460 RGD:1624291
G Smg1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase JBrowse link 1 187,781,577 187,882,833 RGD:1624291
G Smg5 SMG5 nonsense mediated mRNA decay factor JBrowse link 2 187,708,247 187,735,355 RGD:1624291
G Smg6 SMG6 nonsense mediated mRNA decay factor JBrowse link 10
10
61,526,024
61,771,912
61,542,583
62,007,030
RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:13792537
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1624291
G Upf1 UPF1, RNA helicase and ATPase JBrowse link 16 20,824,888 20,845,632 RGD:1624291
RGD:1600115
G Ylpm1 YLP motif containing 1 JBrowse link 6 108,820,774 108,897,209 RGD:1624291
RGD:13792537
negative regulation of protection from non-homologous end joining at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
RGD:1600115
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:1624291
RGD:1600115
G Xrcc4 X-ray repair cross complementing 4 JBrowse link 2 18,674,496 18,927,463 RGD:1624291
negative regulation of t-circle formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
RGD:13792537
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:1600115
G Xrcc5 X-ray repair cross complementing 5 JBrowse link 9 79,659,275 79,748,050 RGD:1624291
RGD:1600115
negative regulation of telomere capping term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
RGD:1600115
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1624291
RGD:1600115
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:1624291
G Smg6 SMG6 nonsense mediated mRNA decay factor JBrowse link 10
10
61,526,024
61,771,912
61,542,583
62,007,030
RGD:1624291
RGD:1600115
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:1600115
negative regulation of telomere maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1624291
RGD:1600115
G Tinf2 TERF1 interacting nuclear factor 2 JBrowse link 15 34,358,697 34,365,085 RGD:1624291
negative regulation of telomere maintenance in response to DNA damage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
RGD:1600115
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:1600115
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acd ACD, shelterin complex subunit and telomerase recruitment factor JBrowse link 19 37,665,289 37,668,043 RGD:1624291
RGD:13792537
G Ctc1 CST telomere replication complex component 1 JBrowse link 10 55,596,172 55,616,873 RGD:1624291
RGD:1600115
G Dcp2 decapping mRNA 2 JBrowse link 18 35,489,274 35,671,676 RGD:1624291
G Exosc10 exosome component 10 JBrowse link 5 165,374,964 165,398,195 RGD:1624291
RGD:1600115
G Gnl3l G protein nucleolar 3 like JBrowse link X 20,037,558 20,070,505 RGD:1624291
RGD:1600115
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 JBrowse link 7 144,865,302 144,871,592 RGD:1624291
RGD:1600115
G Hnrnpc heterogeneous nuclear ribonucleoprotein C JBrowse link 15 28,486,605 28,517,353 RGD:1624291
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 13 96,222,093 96,238,845 RGD:1624291
RGD:1600115
G Nat10 N-acetyltransferase 10 JBrowse link 3 93,658,119 93,698,136 RGD:1624291
RGD:1600115
G Pif1 PIF1 5'-to-3' DNA helicase JBrowse link 8 71,124,477 71,133,460 RGD:1624291
RGD:1600115
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 JBrowse link 15 47,211,682 47,270,343 RGD:1624291
RGD:1600115
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
RGD:1600115
G Stn1 STN1 subunit of CST complex JBrowse link 1 267,281,786 267,315,714 RGD:1600115
RGD:1624291
G Ten1 TEN1 subunit of CST complex JBrowse link 10 105,073,077 105,095,094 RGD:1624291
RGD:13792537
G Tent4b terminal nucleotidyltransferase 4B JBrowse link 19 19,771,289 19,834,759 RGD:1624291
RGD:1600115
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
RGD:1600115
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:1600115
G Tinf2 TERF1 interacting nuclear factor 2 JBrowse link 15 34,358,697 34,365,085 RGD:1624291
RGD:1600115
negative regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Mcrs1 microspherule protein 1 JBrowse link 7 140,910,420 140,919,234 RGD:1624291
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:1624291
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit JBrowse link 1 198,114,514 198,120,061 RGD:1624291
G Slx4 SLX4 structure-specific endonuclease subunit JBrowse link 10 11,787,756 11,808,326 RGD:1624291
RGD:1600115
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Tnks tankyrase JBrowse link 16 60,925,093 61,067,192 RGD:1624291
RGD:1600115
G Tnks2 tankyrase 2 RGD:1624291
negative regulation of telomeric D-loop disassembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
RGD:1600115
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:13792537
positive regulation of t-circle formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
RGD:1600115
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit JBrowse link 1 198,114,514 198,120,061 RGD:1624291
RGD:1600115
G Slx4 SLX4 structure-specific endonuclease subunit JBrowse link 10 11,787,756 11,808,326 RGD:1624291
positive regulation of telomere capping term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:1624291
RGD:1600115
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 14 11,256,163 11,274,684 RGD:1624291
RGD:1600115
G Map2k7 mitogen activated protein kinase kinase 7 JBrowse link 12 2,546,278 2,555,310 RGD:1624291
RGD:1600115
G Map3k4 mitogen activated protein kinase kinase kinase 4 JBrowse link 1 48,625,714 48,711,642 RGD:1624291
RGD:1600115
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
RGD:1600115
G Mapk15 mitogen-activated protein kinase 15 JBrowse link 7 117,041,287 117,061,799 RGD:1624291
RGD:1600115
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:1624291
RGD:1600115
G Mapkapk5 mitogen-activated protein kinase-activated protein kinase 5 JBrowse link 12 40,510,378 40,529,332 RGD:1624291
G Nabp2 nucleic acid binding protein 2 JBrowse link 7 2,820,006 2,825,627 RGD:1624291
RGD:1600115
G Nek2 NIMA-related kinase 2 JBrowse link 13 110,511,546 110,524,750 RGD:1624291
G Nek2l1 NIMA (never in mitosis gene a)-related kinase 2-like 1 JBrowse link 8 15,940,934 15,942,589 RGD:1600115
G Nek7 NIMA-related kinase 7 JBrowse link 13 55,485,759 55,617,534 RGD:1624291
RGD:1600115
G Pkib cAMP-dependent protein kinase inhibitor beta JBrowse link 20 40,616,868 40,712,598 RGD:1624291
RGD:1600115
G Pnkp polynucleotide kinase 3'-phosphatase JBrowse link 1 100,853,475 100,859,202 RGD:1624291
RGD:1600115
G Prkcq protein kinase C, theta JBrowse link 17 70,971,915 71,105,286 RGD:1624291
RGD:1600115
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
G Tnks tankyrase JBrowse link 16 60,925,093 61,067,192 RGD:1624291
RGD:13792537
G Tnks2 tankyrase 2 RGD:1624291
RGD:13792537
positive regulation of telomere maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atrx ATRX, chromatin remodeler JBrowse link X 76,820,110 76,979,155 RGD:1600115
RGD:1624291
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1624291
G Gnl3 G protein nucleolar 3 JBrowse link 16 7,097,580 7,103,518 RGD:1624291
RGD:1600115
G Mre11a MRE11 homolog A, double strand break repair nuclease JBrowse link 8 13,304,355 13,350,329 RGD:1624291
RGD:1600115
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1624291
RGD:1600115
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
RGD:1600115
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 JBrowse link 20 3,329,677 3,344,286 RGD:1600115
RGD:1624291
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:1624291
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
G Sirt6 sirtuin 6 JBrowse link 7 10,937,622 10,943,048 RGD:1624291
RGD:1600115
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acd ACD, shelterin complex subunit and telomerase recruitment factor JBrowse link 19 37,665,289 37,668,043 RGD:1624291
RGD:1600115
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
RGD:1600115
G Atr ATR serine/threonine kinase JBrowse link 8 103,673,578 103,770,886 RGD:1624291
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:1624291
RGD:1600115
G Cct2 chaperonin containing TCP1 subunit 2 JBrowse link 7 60,106,532 60,122,779 RGD:1624291
RGD:1600115
G Cct3 chaperonin containing TCP1 subunit 3 JBrowse link 2 187,669,051 187,693,610 RGD:1624291
RGD:1600115
G Cct4 chaperonin containing TCP1 subunit 4 JBrowse link 14 107,767,392 107,780,270 RGD:1624291
RGD:1600115
G Cct5 chaperonin containing TCP1 subunit 5 JBrowse link 2 84,667,578 84,678,730 RGD:1624291
RGD:1600115
G Cct6a chaperonin containing TCP1 subunit 6A JBrowse link 12 30,491,584 30,501,813 RGD:1624291
RGD:1600115
G Cct7 chaperonin containing TCP1 subunit 7 JBrowse link 4 117,235,023 117,252,265 RGD:1624291
RGD:1600115
G Cct8 chaperonin containing TCP1 subunit 8 JBrowse link 11 27,130,172 27,141,881 RGD:1624291
RGD:1600115
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Dkc1 dyskerin pseudouridine synthase 1 JBrowse link X 155,844,914 155,862,363 RGD:1624291
G Fbxo4 F-box protein 4 JBrowse link 2 53,797,954 53,811,134 RGD:1624291
RGD:1600115
G Hmbox1 homeobox containing 1 JBrowse link 15 48,194,709 48,326,310 RGD:1624291
RGD:1600115
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 JBrowse link 7 144,865,302 144,871,592 RGD:1624291
RGD:1600115
G Map2k7 mitogen activated protein kinase kinase 7 JBrowse link 12 2,546,278 2,555,310 RGD:1624291
RGD:1600115
G Map3k4 mitogen activated protein kinase kinase kinase 4 JBrowse link 1 48,625,714 48,711,642 RGD:1624291
RGD:1600115
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
RGD:1600115
G Mapk15 mitogen-activated protein kinase 15 JBrowse link 7 117,041,287 117,061,799 RGD:1624291
RGD:1600115
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:1624291
RGD:1600115
G Mapkapk5 mitogen-activated protein kinase-activated protein kinase 5 JBrowse link 12 40,510,378 40,529,332 RGD:1624291
G Nek2 NIMA-related kinase 2 JBrowse link 13 110,511,546 110,524,750 RGD:1624291
G Nek2l1 NIMA (never in mitosis gene a)-related kinase 2-like 1 JBrowse link 8 15,940,934 15,942,589 RGD:1600115
G Nek7 NIMA-related kinase 7 JBrowse link 13 55,485,759 55,617,534 RGD:1624291
RGD:1600115
G Parn poly(A)-specific ribonuclease JBrowse link 10 1,309,724 1,461,123 RGD:1624291
RGD:1600115
G Pkib cAMP-dependent protein kinase inhibitor beta JBrowse link 20 40,616,868 40,712,598 RGD:1624291
RGD:1600115
G Pnkp polynucleotide kinase 3'-phosphatase JBrowse link 1 100,853,475 100,859,202 RGD:1624291
RGD:1600115
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:1624291
G Prkcq protein kinase C, theta JBrowse link 17 70,971,915 71,105,286 RGD:1624291
RGD:1600115
G Tcp1 t-complex 1 JBrowse link 1 48,025,664 48,033,343 RGD:1624291
RGD:1600115
G Terc telomerase RNA component JBrowse link 2 116,432,723 116,433,110 RGD:1624291
G Tnks tankyrase JBrowse link 16 60,925,093 61,067,192 RGD:1624291
RGD:1600115
G Xrcc5 X-ray repair cross complementing 5 JBrowse link 9 79,659,275 79,748,050 RGD:1624291
RGD:1600115
positive regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1600115
RGD:1624291
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 JBrowse link 4 81,237,496 81,241,281 RGD:11567256
G Naf1 nuclear assembly factor 1 ribonucleoprotein JBrowse link 16 24,582,000 24,612,773 RGD:1624291
RGD:1600115
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
positive regulation of telomeric loop disassembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
RGD:1600115
regulation of telomere maintenance via telomerase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:1624291
RGD:13792537
G Pot1b protection of telomeres 1B JBrowse link 9 7,845,697 7,902,270 RGD:13792537
G Smg5 SMG5 nonsense mediated mRNA decay factor JBrowse link 2 187,708,247 187,735,355 RGD:13792537
G Smg6 SMG6 nonsense mediated mRNA decay factor JBrowse link 10
10
61,526,024
61,771,912
61,542,583
62,007,030
RGD:13792537
G Smg7 SMG7 nonsense mediated mRNA decay factor JBrowse link 13 70,258,919 70,321,886 RGD:13792537
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:13792537
regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tinf2 TERF1 interacting nuclear factor 2 JBrowse link 15 34,358,697 34,365,085 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17896
    biological regulation 12607
      regulation of biological quality 4125
        regulation of telomere maintenance 84
          negative regulation of telomere maintenance + 37
          positive regulation of telomere maintenance + 53
          regulation of t-circle formation + 6
          regulation of telomere capping + 27
          regulation of telomere maintenance in response to DNA damage + 5
          regulation of telomere maintenance via recombination + 1
          regulation of telomere maintenance via semi-conservative replication + 0
          regulation of telomere maintenance via telomere lengthening + 65
          regulation of telomeric loop disassembly + 3
          regulation of telomeric loop formation + 0
Path 2
Term Annotations click to browse term
  biological_process 17896
    metabolic process 10654
      cellular metabolic process 9742
        cellular aromatic compound metabolic process 5076
          nucleobase-containing compound metabolic process 4872
            nucleic acid metabolic process 4428
              DNA metabolic process 820
                telomere maintenance 127
                  regulation of telomere maintenance 84
                    negative regulation of telomere maintenance + 37
                    positive regulation of telomere maintenance + 53
                    regulation of t-circle formation + 6
                    regulation of telomere capping + 27
                    regulation of telomere maintenance in response to DNA damage + 5
                    regulation of telomere maintenance via recombination + 1
                    regulation of telomere maintenance via semi-conservative replication + 0
                    regulation of telomere maintenance via telomere lengthening + 65
                    regulation of telomeric loop disassembly + 3
                    regulation of telomeric loop formation + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.