Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of telomere maintenance
go back to main search page
Accession:GO:0032205 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
Synonyms:exact_synonym: down regulation of telomere maintenance;   downregulation of telomere maintenance
 narrow_synonym: inhibition of telomere maintenance


show annotations for term's descendants       view all columns           Sort by:
 
negative regulation of telomere maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Tinf2 TERF1 interacting nuclear factor 2 JBrowse link 15 34,358,697 34,365,085 RGD:1624291
negative regulation of protection from non-homologous end joining at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:1624291
G Xrcc4 X-ray repair cross complementing 4 JBrowse link 2 18,674,496 18,927,463 RGD:1624291
negative regulation of t-circle formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
RGD:13792537
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Xrcc5 X-ray repair cross complementing 5 JBrowse link 9 79,659,275 79,748,050 RGD:1624291
negative regulation of telomere capping term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1624291
RGD:1600115
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:1624291
G Smg6 SMG6 nonsense mediated mRNA decay factor JBrowse link 10
10
61,526,024
61,771,912
61,542,583
62,007,030
RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
negative regulation of telomere maintenance in response to DNA damage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:13792537
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acd ACD, shelterin complex subunit and telomerase recruitment factor JBrowse link 19 37,665,289 37,668,043 RGD:1624291
RGD:13792537
G Ctc1 CST telomere replication complex component 1 JBrowse link 10 55,596,172 55,616,873 RGD:1624291
G Dcp2 decapping mRNA 2 JBrowse link 18 35,489,274 35,671,676 RGD:1624291
G Exosc10 exosome component 10 JBrowse link 5 165,374,964 165,398,195 RGD:1624291
G Gnl3l G protein nucleolar 3 like JBrowse link X 20,037,558 20,070,505 RGD:1624291
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 JBrowse link 7 144,865,302 144,871,592 RGD:1624291
RGD:1600115
G Hnrnpc heterogeneous nuclear ribonucleoprotein C JBrowse link 15 28,486,605 28,517,353 RGD:1624291
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 13 96,222,093 96,238,845 RGD:1624291
RGD:13792537
RGD:1600115
G Nat10 N-acetyltransferase 10 JBrowse link 3 93,658,119 93,698,136 RGD:1624291
G Pif1 PIF1 5'-to-3' DNA helicase JBrowse link 8 71,124,477 71,133,460 RGD:1624291
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 JBrowse link 15 47,211,682 47,270,343 RGD:1624291
G Pml PML nuclear body scaffold JBrowse link 8 63,002,515 63,034,310 RGD:1624291
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
G Stn1 STN1 subunit of CST complex JBrowse link 1 267,281,786 267,315,714 RGD:1600115
RGD:1624291
G Ten1 TEN1 subunit of CST complex JBrowse link 10 105,073,077 105,095,094 RGD:1624291
RGD:13792537
G Tent4b terminal nucleotidyltransferase 4B JBrowse link 19 19,771,289 19,834,759 RGD:1624291
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Tinf2 TERF1 interacting nuclear factor 2 JBrowse link 15 34,358,697 34,365,085 RGD:1624291
negative regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Mcrs1 microspherule protein 1 JBrowse link 7 140,910,420 140,919,234 RGD:1624291
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:1624291
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit JBrowse link 1 198,114,514 198,120,061 RGD:1624291
G Slx4 SLX4 structure-specific endonuclease subunit JBrowse link 10 11,787,756 11,808,326 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Tnks tankyrase JBrowse link 16 60,925,093 61,067,192 RGD:1624291
G Tnks2 tankyrase 2 RGD:1624291
negative regulation of telomeric D-loop disassembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
RGD:13792537
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological quality 4252
        regulation of telomere maintenance 83
          negative regulation of telomere maintenance 36
            negative regulation of t-circle formation 3
            negative regulation of telomere capping + 9
            negative regulation of telomere maintenance in response to DNA damage + 5
            negative regulation of telomere maintenance via recombination 1
            negative regulation of telomere maintenance via semi-conservative replication 0
            negative regulation of telomere maintenance via telomere lengthening + 27
            negative regulation of telomeric loop disassembly + 2
            negative regulation of telomeric loop formation 0
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      cellular metabolic process 10918
        cellular aromatic compound metabolic process 5567
          nucleobase-containing compound metabolic process 5344
            nucleic acid metabolic process 4850
              DNA metabolic process 911
                telomere maintenance 128
                  regulation of telomere maintenance 83
                    negative regulation of telomere maintenance 36
                      negative regulation of t-circle formation 3
                      negative regulation of telomere capping + 9
                      negative regulation of telomere maintenance in response to DNA damage + 5
                      negative regulation of telomere maintenance via recombination 1
                      negative regulation of telomere maintenance via semi-conservative replication 0
                      negative regulation of telomere maintenance via telomere lengthening + 27
                      negative regulation of telomeric loop disassembly + 2
                      negative regulation of telomeric loop formation 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.