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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of synaptic transmission, cholinergic
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Accession:GO:0032222 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.


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regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2B calcium/calmodulin dependent protein kinase II beta ISO (MGI:MGI:4352609|PMID:19332541) MGI PMID:19332541 MGI:MGI:4352609 NCBI chr 7:44,930,859...45,040,078
Ensembl chr 7:45,001,267...45,110,342
JBrowse link
negative regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTR6 5-hydroxytryptamine receptor 6 ISO RGD PMID:16987217 RGD:2317005 NCBI chr 1:18,619,683...18,635,822
Ensembl chr 1:19,662,978...19,678,680
JBrowse link
positive regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO phrenic nerve terminals in the presence of adenosine transport inhibitor deoxycoformycin RGD PMID:12679375 RGD:1625693 NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189
JBrowse link
G HTR2C 5-hydroxytryptamine receptor 2C ISO RGD PMID:15266551 RGD:1625007 NCBI chr  X:103,673,172...103,999,133
Ensembl chr  X:114,199,485...114,503,201
JBrowse link
G TACR2 tachykinin receptor 2 ISO RGD PMID:12747940 RGD:5147477 NCBI chr10:65,872,795...65,885,154
Ensembl chr10:68,403,979...68,415,224
JBrowse link
positive regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma ISO RGD PMID:1900518 RGD:2311499 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G LAMA2 laminin subunit alpha 2 ISO (MGI:MGI:77287|PMID:8568931) MGI PMID:8568931 MGI:MGI:77287 NCBI chr 6:126,672,013...127,307,870
Ensembl chr 6:130,781,781...131,415,337
JBrowse link
G MUSK muscle associated receptor tyrosine kinase ISO RGD PMID:16870737 RGD:2317092 NCBI chr 9:81,814,766...81,947,341
Ensembl chr 9:109,980,748...110,107,480
JBrowse link
G NGFR nerve growth factor receptor ISO medial septum and diagonal band of Broca (MS-DBB) neurons stimulated by NGF RGD PMID:18256260 RGD:5508750 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966
JBrowse link
G TAC1 tachykinin precursor 1 ISO RGD PMID:17949415 RGD:2304335 NCBI chr 7:89,675,834...89,684,391
Ensembl chr 7:103,257,501...103,266,389
JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:17949415 RGD:2304335 NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018
JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:15944374 RGD:2306844 NCBI chr 1:6,609,104...6,616,966
Ensembl chr 1:7,854,687...7,864,688
JBrowse link
regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO (MGI:MGI:2654957|PMID:12624181)
(MGI:MGI:3606714|PMID:10686170)
MGI PMID:10686170, PMID:12624181 MGI:MGI:2654957, MGI:MGI:3606714 NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729
JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit ISO (MGI:MGI:3590443|PMID:16162937) MGI PMID:16162937 MGI:MGI:3590443 NCBI chr15:57,523,553...57,550,228
Ensembl chr15:76,487,710...76,512,044
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12524
    regulation of biological process 8652
      regulation of signaling 3054
        regulation of trans-synaptic signaling 497
          modulation of chemical synaptic transmission 496
            regulation of synaptic transmission, cholinergic 14
              modulation by symbiont of host cholinergic synaptic transmission + 0
              negative regulation of synaptic transmission, cholinergic + 1
              positive regulation of synaptic transmission, cholinergic + 10
              regulation of acetylcholine secretion, neurotransmission + 6
Path 2
Term Annotations click to browse term
  biological_process 12524
    cellular process 11624
      cell communication 4361
        cell-cell signaling 1390
          synaptic signaling 637
            trans-synaptic signaling 620
              anterograde trans-synaptic signaling 614
                chemical synaptic transmission 614
                  modulation of chemical synaptic transmission 496
                    regulation of synaptic transmission, cholinergic 14
                      modulation by symbiont of host cholinergic synaptic transmission + 0
                      negative regulation of synaptic transmission, cholinergic + 1
                      positive regulation of synaptic transmission, cholinergic + 10
                      regulation of acetylcholine secretion, neurotransmission + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.