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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of synaptic transmission, cholinergic
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Accession:GO:0032222 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.


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regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2B calcium/calmodulin dependent protein kinase II beta ISO (MGI:MGI:4352609|PMID:19332541) MGI PMID:19332541 MGI:MGI:4352609 NCBI chr 7:44,217,154...44,326,167
Ensembl chr 7:44,217,150...44,334,577
JBrowse link
negative regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTR6 5-hydroxytryptamine receptor 6 ISO RGD PMID:16987217 RGD:2317005 NCBI chr 1:19,664,875...19,680,966
Ensembl chr 1:19,664,875...19,680,966
JBrowse link
negative regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) IC (PMID:1517212) HGNC PMID:1517212 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
positive regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor IEA Ensembl GO_REF:0000107 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357
JBrowse link
G HTR2C 5-hydroxytryptamine receptor 2C ISO RGD PMID:15266551 RGD:1625007 NCBI chr  X:114,584,078...114,910,061
Ensembl chr  X:114,584,078...114,910,061
JBrowse link
G TACR2 tachykinin receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr10:69,403,903...69,416,918
Ensembl chr10:69,403,903...69,416,918
JBrowse link
positive regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma ISO RGD PMID:1900518 RGD:2311499 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G LAMA2 laminin subunit alpha 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:128,883,138...129,516,566
Ensembl chr 6:128,883,138...129,516,566
Ensembl chr 6:128,883,138...129,516,566
JBrowse link
G MUSK muscle associated receptor tyrosine kinase ISO RGD PMID:16870737 RGD:2317092 NCBI chr 9:110,668,189...110,806,633
Ensembl chr 9:110,668,779...110,806,558
JBrowse link
G NGFR nerve growth factor receptor ISO medial septum and diagonal band of Broca (MS-DBB) neurons stimulated by NGF RGD PMID:18256260 RGD:5508750 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008
JBrowse link
G TAC1 tachykinin precursor 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
JBrowse link
G TACR1 tachykinin receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520
JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:15944374 RGD:2306844 NCBI chr 1:7,846,345...7,913,615
Ensembl chr 1:7,843,083...7,853,512
JBrowse link
regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1A calcium voltage-gated channel subunit alpha1 A IEA Ensembl GO_REF:0000107 NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,633,025
JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit ISS UniProtKB GO_REF:0000024 NCBI chr15:78,593,052...78,620,996
Ensembl chr15:78,593,052...78,621,295
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18626
    regulation of biological process 12621
      regulation of signaling 3996
        regulation of trans-synaptic signaling 666
          modulation of chemical synaptic transmission 665
            regulation of synaptic transmission, cholinergic 15
              modulation by symbiont of host cholinergic synaptic transmission + 0
              negative regulation of synaptic transmission, cholinergic + 2
              positive regulation of synaptic transmission, cholinergic + 10
              regulation of acetylcholine secretion, neurotransmission + 6
Path 2
Term Annotations click to browse term
  biological_process 18626
    cellular process 17648
      cell communication 7234
        cell-cell signaling 2096
          synaptic signaling 977
            trans-synaptic signaling 951
              anterograde trans-synaptic signaling 944
                chemical synaptic transmission 944
                  modulation of chemical synaptic transmission 665
                    regulation of synaptic transmission, cholinergic 15
                      modulation by symbiont of host cholinergic synaptic transmission + 0
                      negative regulation of synaptic transmission, cholinergic + 2
                      positive regulation of synaptic transmission, cholinergic + 10
                      regulation of acetylcholine secretion, neurotransmission + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.