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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of synaptic transmission, cholinergic
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Accession:GO:0032222 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.


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regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2b calcium/calmodulin-dependent protein kinase II, beta IMP (MGI:MGI:4352609|PMID:19332541) MGI PMID:19332541 MGI:MGI:4352609 NCBI chr11:5,969,629...6,066,357
Ensembl chr11:5,969,644...6,066,362
JBrowse link
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 IC (MGI:MGI:4437154|PMID:20164328) ARUK-UCL PMID:20164328 MGI:MGI:4437154 NCBI chr 7:63,098,692...63,212,526
Ensembl chr 7:63,098,692...63,212,569
JBrowse link
negative regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr6 5-hydroxytryptamine (serotonin) receptor 6 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 4:139,059,706...139,075,570
Ensembl chr 4:139,061,108...139,075,570
JBrowse link
positive regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr10:75,316,877...75,334,792
Ensembl chr10:75,316,877...75,334,784
JBrowse link
G Htr2c 5-hydroxytryptamine (serotonin) receptor 2C ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr  X:146,962,464...147,197,277
Ensembl chr  X:146,962,513...147,197,277
JBrowse link
G Tacr2 tachykinin receptor 2 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr10:62,252,438...62,265,990
Ensembl chr10:62,252,438...62,265,990
JBrowse link
positive regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Lama2 laminin, alpha 2 IMP (MGI:MGI:77287|PMID:8568931) MGI PMID:8568931 MGI:MGI:77287 NCBI chr10:26,981,285...27,617,191
Ensembl chr10:26,980,036...27,619,758
JBrowse link
G Musk muscle, skeletal, receptor tyrosine kinase ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 4:58,285,729...58,377,848
Ensembl chr 4:58,285,960...58,374,303
JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr11:95,568,818...95,587,698
Ensembl chr11:95,568,818...95,587,735
JBrowse link
G Tac1 tachykinin 1 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 6:82,402,003...82,560,104
Ensembl chr 6:82,402,334...82,560,104
JBrowse link
G Uts2 urotensin 2 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 4:150,997,097...151,001,810
Ensembl chr 4:150,997,097...151,001,810
JBrowse link
regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit IMP (MGI:MGI:2654957|PMID:12624181)
(MGI:MGI:3606714|PMID:10686170)
MGI PMID:10686170, PMID:12624181 MGI:MGI:2654957, MGI:MGI:3606714 NCBI chr 8:84,338,631...84,640,251
Ensembl chr 8:84,338,639...84,640,246
JBrowse link
G Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 IMP (MGI:MGI:3590443|PMID:16162937) MGI PMID:16162937 MGI:MGI:3590443 NCBI chr 9:55,010,117...55,026,562
Ensembl chr 9:55,010,111...55,026,562
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23369
    regulation of biological process 12448
      regulation of signaling 3617
        regulation of trans-synaptic signaling 689
          modulation of chemical synaptic transmission 688
            regulation of synaptic transmission, cholinergic 15
              modulation by symbiont of host cholinergic synaptic transmission + 0
              negative regulation of synaptic transmission, cholinergic + 1
              positive regulation of synaptic transmission, cholinergic + 10
              regulation of acetylcholine secretion, neurotransmission + 6
Path 2
Term Annotations click to browse term
  biological_process 23369
    cellular process 17359
      cell communication 7015
        cell-cell signaling 1788
          synaptic signaling 928
            trans-synaptic signaling 898
              anterograde trans-synaptic signaling 890
                chemical synaptic transmission 890
                  modulation of chemical synaptic transmission 688
                    regulation of synaptic transmission, cholinergic 15
                      modulation by symbiont of host cholinergic synaptic transmission + 0
                      negative regulation of synaptic transmission, cholinergic + 1
                      positive regulation of synaptic transmission, cholinergic + 10
                      regulation of acetylcholine secretion, neurotransmission + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.