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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of synaptic transmission, cholinergic
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Accession:GO:0032222 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.


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regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2B calcium/calmodulin dependent protein kinase II beta ISO (MGI:MGI:4352609|PMID:19332541) MGI PMID:19332541 MGI:MGI:4352609 NCBI chr18:50,862,225...50,956,263
Ensembl chr18:50,861,466...50,957,945
JBrowse link
negative regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTR6 5-hydroxytryptamine receptor 6 ISO RGD PMID:16987217 RGD:2317005 NCBI chr 6:78,077,358...78,092,211 JBrowse link
positive regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO phrenic nerve terminals in the presence of adenosine transport inhibitor deoxycoformycin RGD PMID:12679375 RGD:1625693 NCBI chr14:49,467,186...49,485,845
Ensembl chr14:49,468,862...49,485,841
JBrowse link
G HTR2C 5-hydroxytryptamine receptor 2C ISO RGD PMID:15266551 RGD:1625007 NCBI chr  X:94,053,415...94,313,352
Ensembl chr  X:94,053,456...94,313,356
JBrowse link
G TACR2 tachykinin receptor 2 ISO RGD PMID:12747940 RGD:5147477 NCBI chr14:72,463,405...72,476,034
Ensembl chr14:72,462,046...72,475,554
JBrowse link
positive regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma ISO RGD PMID:1900518 RGD:2311499 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
G LAMA2 laminin subunit alpha 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:33,765,412...34,359,741
Ensembl chr 1:33,867,639...34,359,698
JBrowse link
G MUSK muscle associated receptor tyrosine kinase ISO RGD PMID:16870737 RGD:2317092 NCBI chr 1:251,650,151...251,758,538
Ensembl chr 1:251,650,710...251,756,608
JBrowse link
G NGFR nerve growth factor receptor ISO medial septum and diagonal band of Broca (MS-DBB) neurons stimulated by NGF RGD PMID:18256260 RGD:5508750 NCBI chr12:25,699,410...25,720,355
Ensembl chr12:25,699,427...25,720,357
JBrowse link
G TAC1 tachykinin precursor 1 ISO RGD PMID:17949415 RGD:2304335 NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,535...77,206,526
JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:17949415 RGD:2304335 NCBI chr 3:67,839,367...68,021,733
Ensembl chr 3:67,839,411...68,021,728
JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:15944374 RGD:2306844 NCBI chr 6:68,552,889...68,560,827 JBrowse link
regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO (MGI:MGI:2654957|PMID:12624181)
(MGI:MGI:3606714|PMID:10686170)
MGI PMID:10686170, PMID:12624181 MGI:MGI:2654957, MGI:MGI:3606714 NCBI chr 2:65,491,784...65,871,068 JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit ISO (MGI:MGI:3590443|PMID:16162937) MGI PMID:16162937 MGI:MGI:3590443 NCBI chr 7:47,361,710...47,382,743
Ensembl chr 7:47,361,778...47,384,303
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    regulation of biological process 11420
      regulation of signaling 3400
        regulation of trans-synaptic signaling 599
          modulation of chemical synaptic transmission 598
            regulation of synaptic transmission, cholinergic 14
              modulation by symbiont of host cholinergic synaptic transmission + 0
              negative regulation of synaptic transmission, cholinergic + 1
              positive regulation of synaptic transmission, cholinergic + 10
              regulation of acetylcholine secretion, neurotransmission + 6
Path 2
Term Annotations click to browse term
  biological_process 16524
    cellular process 15759
      cell communication 6524
        cell-cell signaling 1643
          synaptic signaling 829
            trans-synaptic signaling 803
              anterograde trans-synaptic signaling 797
                chemical synaptic transmission 797
                  modulation of chemical synaptic transmission 598
                    regulation of synaptic transmission, cholinergic 14
                      modulation by symbiont of host cholinergic synaptic transmission + 0
                      negative regulation of synaptic transmission, cholinergic + 1
                      positive regulation of synaptic transmission, cholinergic + 10
                      regulation of acetylcholine secretion, neurotransmission + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.