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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of synaptic transmission, cholinergic
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Accession:GO:0032222 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.


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regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2b calcium/calmodulin dependent protein kinase II beta ISO (MGI:MGI:4352609|PMID:19332541) MGI PMID:19332541 MGI:MGI:4352609 NCBI chrNW_004936478:19,183,493...19,278,457 JBrowse link
negative regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr6 5-hydroxytryptamine receptor 6 ISO RGD PMID:16987217 RGD:2317005 NCBI chrNW_004936474:5,848,719...5,858,520 JBrowse link
positive regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor ISO phrenic nerve terminals in the presence of adenosine transport inhibitor deoxycoformycin RGD PMID:12679375 RGD:1625693 NCBI chrNW_004936619:597,970...618,564 JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C ISO RGD PMID:15266551 RGD:1625007 NCBI chrNW_004936499:1,002,083...1,109,446 JBrowse link
G Tacr2 tachykinin receptor 2 ISO RGD PMID:12747940 RGD:5147477 NCBI chrNW_004936521:9,053,179...9,065,790 JBrowse link
positive regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO RGD PMID:1900518 RGD:2311499 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Lama2 laminin subunit alpha 2 ISO (MGI:MGI:77287|PMID:8568931) MGI PMID:8568931 MGI:MGI:77287 NCBI chrNW_004936639:259,662...825,170 JBrowse link
G Musk muscle associated receptor tyrosine kinase ISO RGD PMID:16870737 RGD:2317092 NCBI chrNW_004936559:2,387,019...2,486,685 JBrowse link
G Ngfr nerve growth factor receptor ISO medial septum and diagonal band of Broca (MS-DBB) neurons stimulated by NGF RGD PMID:18256260 RGD:5508750 NCBI chrNW_004936490:12,038,500...12,057,257 JBrowse link
G Tac1 tachykinin precursor 1 ISO RGD PMID:17949415 RGD:2304335 NCBI chrNW_004936585:2,932,783...2,941,141 JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:17949415 RGD:2304335 NCBI chrNW_004936556:1,266,621...1,421,271 JBrowse link
G Uts2 urotensin 2 ISO RGD PMID:15944374 RGD:2306844 NCBI chrNW_004936623:2,339,259...2,345,717 JBrowse link
regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO (MGI:MGI:2654957|PMID:12624181)
(MGI:MGI:3606714|PMID:10686170)
MGI PMID:10686170, PMID:12624181 MGI:MGI:2654957, MGI:MGI:3606714 NCBI chrNW_004936659:2,201,606...2,269,625 JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit ISO (MGI:MGI:3590443|PMID:16162937) MGI PMID:16162937 MGI:MGI:3590443 NCBI chrNW_004936471:36,427,598...36,447,903 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11962
    regulation of biological process 8316
      regulation of signaling 2966
        regulation of trans-synaptic signaling 490
          modulation of chemical synaptic transmission 489
            regulation of synaptic transmission, cholinergic 14
              modulation by symbiont of host cholinergic synaptic transmission + 0
              negative regulation of synaptic transmission, cholinergic + 1
              positive regulation of synaptic transmission, cholinergic + 10
              regulation of acetylcholine secretion, neurotransmission + 6
Path 2
Term Annotations click to browse term
  biological_process 11962
    cellular process 11135
      cell communication 4234
        cell-cell signaling 1360
          synaptic signaling 630
            trans-synaptic signaling 613
              anterograde trans-synaptic signaling 607
                chemical synaptic transmission 607
                  modulation of chemical synaptic transmission 489
                    regulation of synaptic transmission, cholinergic 14
                      modulation by symbiont of host cholinergic synaptic transmission + 0
                      negative regulation of synaptic transmission, cholinergic + 1
                      positive regulation of synaptic transmission, cholinergic + 10
                      regulation of acetylcholine secretion, neurotransmission + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.