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ONTOLOGY REPORT - ANNOTATIONS


Term:cytoplasm to vacuole transport by the Cvt pathway
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Accession:GO:0032258 term browser browse the term
Definition:A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast.
Synonyms:exact_synonym: cytoplasm to vacuole targeting;   protein localization by the Cvt pathway


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  biological_process 19858
    cellular process 18617
      process utilizing autophagic mechanism 459
        cytoplasm to vacuole transport by the Cvt pathway 0
          Cvt vesicle assembly 0
          regulation of protein localization by the Cvt pathway 0
Path 2
Term Annotations click to browse term
  biological_process 19858
    localization 6457
      establishment of localization 4907
        transport 4764
          nitrogen compound transport 2188
            amide transport 1855
              peptide transport 1821
                protein transport 1763
                  intracellular protein transport 1012
                    protein targeting 321
                      protein targeting to vacuole 44
                        cytoplasm to vacuole transport by the Cvt pathway 0
                          Cvt vesicle assembly 0
                          regulation of protein localization by the Cvt pathway 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.