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ONTOLOGY REPORT - ANNOTATIONS


Term:cytoplasm to vacuole transport by the Cvt pathway
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Accession:GO:0032258 term browser browse the term
Definition:A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast.
Synonyms:exact_synonym: cytoplasm to vacuole targeting;   protein localization by the Cvt pathway


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cytoplasm to vacuole transport by the Cvt pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:13792537
G Becn2 beclin 2 JBrowse link 13 93,971,720 93,974,467 RGD:13792537
G Trappc8 trafficking protein particle complex 8 JBrowse link 18 15,298,673 15,375,034 RGD:13792537

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Path 1
Term Annotations click to browse term
  biological_process 18166
    cellular process 16266
      process utilizing autophagic mechanism 400
        cytoplasm to vacuole transport by the Cvt pathway 3
          Cvt vesicle assembly 0
          regulation of protein localization by the Cvt pathway 0
Path 2
Term Annotations click to browse term
  biological_process 18166
    localization 6061
      establishment of localization 4655
        transport 4517
          nitrogen compound transport 2185
            amide transport 1867
              peptide transport 1834
                protein transport 1777
                  intracellular protein transport 957
                    protein targeting 276
                      protein targeting to vacuole 38
                        cytoplasm to vacuole transport by the Cvt pathway 3
                          Cvt vesicle assembly 0
                          regulation of protein localization by the Cvt pathway 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.