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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of icosanoid secretion
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Accession:GO:0032303 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell.
Synonyms:exact_synonym: regulation of eicosanoid secretion


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negative regulation of arachidonic acid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5pf ATP synthase peripheral stalk subunit F6 IDA RGD PMID:9822642 RGD:13800919 NCBI chr11:24,286,806...24,294,419
Ensembl chr11:24,286,787...24,294,179
JBrowse link
G Hrh2 histamine receptor H 2 IDA RGD PMID:1313563 RGD:9685527 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441
JBrowse link
G Pla2r1 phospholipase A2 receptor 1 ISO (MGI:MGI:5297792|PMID:11830583) RGD PMID:11830583 MGI:MGI:5297792 NCBI chr 3:46,488,963...46,621,873
Ensembl chr 3:46,488,186...46,621,873
JBrowse link
negative regulation of icosanoid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:18799632 RGD:2313549 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
negative regulation of prostaglandin secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl4 acyl-CoA synthetase long-chain family member 4 ISO (PMID:21242590) RGD PMID:21242590 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 IMP
IDA
RGD PMID:19474762, PMID:11581303 RGD:13800898, RGD:13800911 NCBI chr11:24,286,806...24,294,419
Ensembl chr11:24,286,787...24,294,179
JBrowse link
positive regulation of arachidonic acid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avpr1b arginine vasopressin receptor 1B ISO (PMID:9322919) RGD PMID:9322919 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831
JBrowse link
G Mif macrophage migration inhibitory factor ISO (MGI:MGI:4437204|PMID:10364264) RGD PMID:10364264 MGI:MGI:4437204 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:11852105 RGD:9743869 NCBI chr 3:175,982,313...176,046,345
Ensembl chr 3:175,885,894...176,046,345
JBrowse link
G Pla2g10 phospholipase A2, group X ISO
IEA
(MGI:MGI:5051938|PMID:20844270)
GO_REF:0000107
RGD
Ensembl
PMID:20844270 GO_REF:0000107, MGI:MGI:5051938 NCBI chr10:1,509,732...1,520,970
Ensembl chr10:1,509,732...1,520,970
JBrowse link
G Pla2g6 phospholipase A2 group VI IMP
IDA
RGD PMID:20732873, PMID:15576376 RGD:6482749, RGD:6482753 NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347
JBrowse link
G Pla2r1 phospholipase A2 receptor 1 ISO
ISS
(MGI:MGI:5297793|PMID:10946309)
GO_REF:0000024
RGD
UniProt
PMID:10946309 GO_REF:0000024, MGI:MGI:5297793 NCBI chr 3:46,488,963...46,621,873
Ensembl chr 3:46,488,186...46,621,873
JBrowse link
G Sstr4 somatostatin receptor 4 IDA RGD PMID:8175684 RGD:2325010 NCBI chr 3:142,739,781...142,741,644
Ensembl chr 3:142,739,781...142,741,644
JBrowse link
positive regulation of fever generation by positive regulation of prostaglandin secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfrsf11a TNF receptor superfamily member 11A ISO (MGI:MGI:4413614|PMID:19940926) RGD PMID:19940926 MGI:MGI:4413614 NCBI chr13:25,778,306...25,835,802
Ensembl chr13:25,778,317...25,835,957
JBrowse link
G Tnfsf11 TNF superfamily member 11 ISO (MGI:MGI:4413614|PMID:19940926) RGD PMID:19940926 MGI:MGI:4413614 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
positive regulation of prostaglandin secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 IDA RGD PMID:1324048 RGD:8662308 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:8612624 RGD:7800677 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta ISO
IEA
(MGI:MGI:4413614|PMID:19940926)
GO_REF:0000107
RGD
Ensembl
PMID:19940926 GO_REF:0000107, MGI:MGI:4413614 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 IMP RGD PMID:12649265 RGD:7495834 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:9786861 RGD:2304243 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:9575824 RGD:2304227 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G P2rx7 purinergic receptor P2X 7 ISO MGI:MGI:2386080 (MGI:MGI:3616954|PMID:16269410) RGD PMID:16269410 MGI:MGI:3616954 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G P2ry2 purinergic receptor P2Y2 IDA RGD PMID:15840771 RGD:2316683 NCBI chr 1:166,031,228...166,045,423
Ensembl chr 1:166,031,272...166,037,424
JBrowse link
G Pla2g10 phospholipase A2, group X ISO
IEA
(PMID:18511424)
GO_REF:0000107
RGD
Ensembl
PMID:18511424 GO_REF:0000107 NCBI chr10:1,509,732...1,520,970
Ensembl chr10:1,509,732...1,520,970
JBrowse link
G Pla2g3 phospholipase A2, group III ISO
IEA
MGI:MGI:4461174 (MGI:MGI:6108995|PMID:28947740)
GO_REF:0000107
RGD
Ensembl
PMID:28947740 GO_REF:0000107, MGI:MGI:6108995 NCBI chr14:83,724,828...83,730,614
Ensembl chr14:83,724,933...83,730,614
JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO
IEA
MGI:MGI:2385582 (MGI:MGI:5779244|PMID:26828067)
GO_REF:0000107
RGD
Ensembl
PMID:26828067 GO_REF:0000107, MGI:MGI:5779244 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Ptges prostaglandin E synthase ISO
IEA
MGI:MGI:3051640 (MGI:MGI:5779244|PMID:26828067)
GO_REF:0000107
RGD
Ensembl
PMID:26828067 GO_REF:0000107, MGI:MGI:5779244 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO (PMID:19790068) RGD PMID:19790068 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
positive regulation of prostaglandin secretion involved in immune response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mif macrophage migration inhibitory factor ISO (MGI:MGI:2156302|PMID:11756671) RGD PMID:11756671 MGI:MGI:2156302 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
regulation of arachidonic acid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syk spleen associated tyrosine kinase IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:87668|PMID:9171347)
Ensembl
UniProt
RGD
PMID:9171347 GO_REF:0000024, GO_REF:0000107, MGI:MGI:87668 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link
regulation of prostaglandin secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 ISO (PMID:18703674) RGD PMID:18703674 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    regulation of biological process 13071
      regulation of localization 3034
        regulation of transport 2028
          regulation of secretion 861
            regulation of icosanoid secretion 27
              negative regulation of icosanoid secretion + 5
              positive regulation of icosanoid secretion + 21
              regulation of arachidonic acid secretion + 10
              regulation of prostaglandin secretion + 19
Path 2
Term Annotations click to browse term
  biological_process 20014
    localization 6486
      establishment of localization 4918
        transport 4774
          ion transport 1783
            anion transport 676
              organic anion transport 531
                carboxylic acid transport 368
                  monocarboxylic acid transport 190
                    fatty acid transport 103
                      regulation of fatty acid transport 37
                        regulation of icosanoid secretion 27
                          negative regulation of icosanoid secretion + 5
                          positive regulation of icosanoid secretion + 21
                          regulation of arachidonic acid secretion + 10
                          regulation of prostaglandin secretion + 19
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.