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ONTOLOGY REPORT - ANNOTATIONS


Term:aldosterone biosynthetic process
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Accession:GO:0032342 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.


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aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:4891166
RGD:1600115
RGD:1624291
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 RGD:4891166
RGD:13792537
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 7 116,248,759 116,255,205 RGD:727991
RGD:13792537
RGD:1624291
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 JBrowse link 7 116,155,928 116,161,781 RGD:1624291
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 1 176,940,424 176,983,076 RGD:1624291
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:4891166
RGD:1624291
RGD:1600115
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:1624291
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:7243836
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clcn2 chloride voltage-gated channel 2 JBrowse link 11 82,862,664 82,876,165 RGD:1600115
RGD:1624291
G LOC108348101 chloride channel protein 2 JBrowse link 11 83,883,428 83,897,396 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    cellular process 17241
      cellular metabolic process 10567
        cellular ketone metabolic process 213
          aldosterone metabolic process 14
            aldosterone biosynthetic process 13
              negative regulation of aldosterone biosynthetic process 4
              positive regulation of aldosterone biosynthetic process 3
              regulation of aldosterone biosynthetic process + 9
Path 2
Term Annotations click to browse term
  biological_process 19336
    biological regulation 13340
      regulation of biological quality 4239
        regulation of hormone levels 593
          hormone metabolic process 236
            cellular hormone metabolic process 122
              C21-steroid hormone metabolic process 45
                C21-steroid hormone biosynthetic process 23
                  aldosterone biosynthetic process 13
                    negative regulation of aldosterone biosynthetic process 4
                    positive regulation of aldosterone biosynthetic process 3
                    regulation of aldosterone biosynthetic process + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.