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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of sterol transport
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Accession:GO:0032372 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms:exact_synonym: down regulation of sterol transport;   downregulation of sterol transport
 narrow_synonym: inhibition of sterol transport


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negative regulation of cholesterol efflux term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO
IEA
(PMID:21810484)
GO_REF:0000107
RGD
Ensembl
PMID:21810484 GO_REF:0000107 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G Apoe apolipoprotein E ISO (PMID:12042316) RGD PMID:12042316 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Egf epidermal growth factor ISO (MGI:MGI:4460848|PMID:20037141) RGD PMID:20037141 MGI:MGI:4460848 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO (MGI:MGI:4411947|PMID:19752193) RGD PMID:19752193 MGI:MGI:4411947 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977
JBrowse link
G Pla2g10 phospholipase A2, group X ISO
IEA
(MGI:MGI:5051938|PMID:20844270)
GO_REF:0000107
RGD
Ensembl
PMID:20844270 GO_REF:0000107, MGI:MGI:5051938 NCBI chr10:1,509,732...1,520,970
Ensembl chr10:1,509,732...1,520,970
JBrowse link
G Shh sonic hedgehog signaling molecule ISO
IEA
(MGI:MGI:5306540|PMID:21931618)
GO_REF:0000107
RGD
Ensembl
PMID:21931618 GO_REF:0000107, MGI:MGI:5306540 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 ISO
IEA
(PMID:15358760)
GO_REF:0000107
RGD
Ensembl
PMID:15358760 GO_REF:0000107 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link
negative regulation of cholesterol import term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 ISO (PMID:10764676) RGD PMID:10764676 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apoc3 apolipoprotein C3 ISO
IEA
(PMID:15778093)
GO_REF:0000107
RGD
Ensembl
PMID:15778093 GO_REF:0000107 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
negative regulation of cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 ISO (PMID:8636092) RGD PMID:8636092 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apoc1 apolipoprotein C1 ISO
IBA
(PMID:10978346)
PMID:21873635
RGD PMID:10978346, PMID:21873635 RGD:13792537 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Apoc2 apolipoprotein C2 ISO (PMID:15778093) RGD PMID:15778093 NCBI chr 1:80,589,023...80,593,991
Ensembl chr 1:80,589,023...80,594,136
JBrowse link
G LOC100910181 apolipoprotein C-I-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G NEWGENE_2134 apolipoprotein C1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:80,606,634...80,609,954
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
negative regulation of cholesterol transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 ISO (PMID:8106353) RGD PMID:8106353 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO
IEA
(PMID:21810484)
GO_REF:0000107
RGD
Ensembl
PMID:21810484 GO_REF:0000107 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO (PMID:22848640) RGD PMID:22848640 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    negative regulation of biological process 5696
      negative regulation of transport 552
        negative regulation of lipid transport 37
          negative regulation of sterol transport 16
            negative regulation of cholesterol transport + 16
            negative regulation of intracellular sterol transport + 2
            negative regulation of sterol import + 2
Path 2
Term Annotations click to browse term
  biological_process 20014
    localization 6486
      establishment of localization 4918
        transport 4774
          organic substance transport 2612
            lipid transport 401
              sterol transport 106
                regulation of sterol transport 57
                  negative regulation of sterol transport 16
                    negative regulation of cholesterol transport + 16
                    negative regulation of intracellular sterol transport + 2
                    negative regulation of sterol import + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.