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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
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Accession:GO:0032435 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
Synonyms:exact_synonym: down regulation of proteasomal ubiquitin-dependent protein catabolic process;   downregulation of proteasomal ubiquitin-dependent protein catabolic process
 narrow_synonym: inhibition of proteasomal ubiquitin-dependent protein catabolic process


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negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bag5 BAG cochaperone 5 JBrowse link 6 136,180,640 136,185,651 RGD:1624291
G Bag6 BAG cochaperone 6 JBrowse link 20 5,124,512 5,138,084 RGD:1624291
RGD:1600115
G Camlg calcium modulating ligand JBrowse link 17 9,523,792 9,534,683 RGD:1624291
G Ccar2 cell cycle and apoptosis regulator 2 JBrowse link 15 51,818,887 51,834,443 RGD:1624291
G Clec16a C-type lectin domain containing 16A JBrowse link 10 5,002,196 5,196,914 RGD:1624291
G Ddrgk1 DDRGK domain containing 1 JBrowse link 3 123,195,580 123,206,828 RGD:1624291
G Fhit fragile histidine triad diadenosine triphosphatase JBrowse link 15 15,697,292 16,862,873 RGD:1624291
RGD:13792537
RGD:1600115
G Gipc1 GIPC PDZ domain containing family, member 1 JBrowse link 19 24,786,604 24,798,231 RGD:1624291
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 JBrowse link 9 17,817,791 17,823,163 RGD:1600115
RGD:1624291
G Klhl40 kelch-like family member 40 JBrowse link 8 130,416,265 130,421,871 RGD:1624291
RGD:13792537
G Map1a microtubule-associated protein 1A JBrowse link 3 113,251,918 113,272,193 RGD:1624291
G Mtm1 myotubularin 1 JBrowse link 6 18,821,821 18,840,449 RGD:1624291
G N4bp1 Nedd4 binding protein 1 JBrowse link 19 21,218,123 21,268,539 RGD:1624291
G Nop53 NOP53 ribosome biogenesis factor JBrowse link 1 77,836,522 77,843,991 RGD:1624291
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 71,540,870 71,585,906 RGD:1600115
RGD:1624291
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Pbk PDZ binding kinase JBrowse link 15 42,489,253 42,500,377 RGD:1624291
G Rpl11 ribosomal protein L11 JBrowse link 5 154,390,809 154,394,412 RGD:1624291
RGD:1600115
G Rybp RING1 and YY1 binding protein JBrowse link 4 132,689,623 132,740,823 RGD:1624291
G Sdcbp syndecan binding protein JBrowse link 5 19,471,664 19,498,499 RGD:1624291
RGD:1600115
G Senp1 SUMO specific peptidase 1 JBrowse link 7 139,626,444 139,684,587 RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 JBrowse link 8 118,206,678 118,326,264 RGD:1624291
G Taf9 TATA-box binding protein associated factor 9 JBrowse link 2 30,664,407 30,668,414 RGD:1624291
G Tlk2 tousled-like kinase 2 JBrowse link 10 93,410,181 93,507,277 RGD:1624291
G Trim39 tripartite motif-containing 39 JBrowse link 20 2,500,691 2,514,546 RGD:1600115
RGD:13792537
RGD:1624291
G Ubxn1 UBX domain protein 1 JBrowse link 1 225,067,953 225,071,944 RGD:1624291
RGD:1600115
G Uchl5 ubiquitin C-terminal hydrolase L5 JBrowse link 13 60,568,102 60,603,812 RGD:1624291
G Usp7 ubiquitin specific peptidase 7 JBrowse link 10 6,930,462 7,019,910 RGD:1600115
RGD:1624291
G Wac WW domain containing adaptor with coiled-coil JBrowse link 17 60,887,606 60,946,630 RGD:1624291
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sgta small glutamine rich tetratricopeptide repeat containing alpha JBrowse link 7 11,521,949 11,538,691 RGD:1624291
RGD:1600115
G Svip small VCP interacting protein JBrowse link 1 107,368,117 107,373,807 RGD:10047192
RGD:1624291
G Usp14 ubiquitin specific peptidase 14 JBrowse link 18 1,178,785 1,216,573 RGD:1624291
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Styx serine/threonine/tyrosine interacting protein JBrowse link 15 19,690,079 19,720,683 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      primary metabolic process 10563
        protein metabolic process 6070
          protein catabolic process 970
            proteasomal protein catabolic process 478
              proteasome-mediated ubiquitin-dependent protein catabolic process 412
                negative regulation of proteasomal ubiquitin-dependent protein catabolic process 34
                  negative regulation of ER-associated ubiquitin-dependent protein catabolic process 3
                  negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process 1
                  negative regulation of anaphase-promoting complex-dependent catabolic process 0
                  negative regulation of transcription factor catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      organic substance metabolic process 11299
        macromolecule metabolic process 9767
          macromolecule catabolic process 1309
            protein catabolic process 970
              cellular protein catabolic process 804
                proteolysis involved in cellular protein catabolic process 751
                  modification-dependent protein catabolic process 639
                    ubiquitin-dependent protein catabolic process 628
                      proteasome-mediated ubiquitin-dependent protein catabolic process 412
                        regulation of proteasomal ubiquitin-dependent protein catabolic process 131
                          negative regulation of proteasomal ubiquitin-dependent protein catabolic process 34
                            negative regulation of ER-associated ubiquitin-dependent protein catabolic process 3
                            negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process 1
                            negative regulation of anaphase-promoting complex-dependent catabolic process 0
                            negative regulation of transcription factor catabolic process 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.