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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of phosphoprotein phosphatase activity
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Accession:GO:0032515 term browser browse the term
Definition:Any process that stops or reduces the activity of a phosphoprotein phosphatase.
Synonyms:exact_synonym: down regulation of phosphoprotein phosphatase activity;   downregulation of phosphoprotein phosphatase activity
 narrow_synonym: down regulation of calcineurin activity;   down regulation of protein phosphatase type 2A activity;   down regulation of protein phosphatase type 2B activity;   downregulation of calcineurin activity;   downregulation of protein phosphatase type 2A activity;   downregulation of protein phosphatase type 2B activity;   inhibition of calcineurin activity;   inhibition of phosphoprotein phosphatase activity;   inhibition of protein phosphatase type 2A activity;   inhibition of protein phosphatase type 2B activity;   negative regulation of calcineurin activity;   negative regulation of protein phosphatase type 2A activity;   negative regulation of protein phosphatase type 2B activity
 related_synonym: down regulation of protein phosphatase 2 activity;   down regulation of protein phosphatase 3 activity;   downregulation of protein phosphatase 2 activity;   downregulation of protein phosphatase 3 activity;   inhibition of protein phosphatase 2 activity;   inhibition of protein phosphatase 3 activity;   negative regulation of protein phosphatase 2 activity;   regulation of protein phosphatase 3 activity
 alt_id: GO:0032513;   GO:0034048


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negative regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07027306.1 RGD:1600115
G AABR07051376.1 RGD:1600115
G Arpp19 cAMP-regulated phosphoprotein 19 JBrowse link 8 81,949,577 81,972,054 RGD:1600115
G Bod1 biorientation of chromosomes in cell division 1 JBrowse link 10 16,259,728 16,266,069 RGD:1624291
RGD:13792537
G Bod1l1 biorientation of chromosomes in cell division 1-like 1 JBrowse link 14 73,738,137 73,792,935 RGD:13792537
G Cabin1 calcineurin binding protein 1 JBrowse link 20 13,836,032 13,963,003 RGD:1600115
G Cmya5 cardiomyopathy associated 5 JBrowse link 2 22,646,694 22,744,536 RGD:1624291
G Cry2 cryptochrome circadian regulator 2 JBrowse link 3 81,314,151 81,344,143 RGD:1624291
G Ensa endosulfine alpha JBrowse link 2 197,752,544 197,759,882 RGD:1600115
G Fam122a family with sequence similarity 122A JBrowse link 1 242,372,458 242,373,764 RGD:1600115
G Fkbp1a FKBP prolyl isomerase 1A JBrowse link 3 147,042,944 147,062,725 RGD:1624291
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:1624291
RGD:1600115
G Lmtk2 lemur tyrosine kinase 2 JBrowse link 12 12,409,876 12,546,111 RGD:1600115
G LOC100360828 cAMP-regulated phosphoprotein 19-like JBrowse link 8 119,105,962 119,106,371 RGD:1600115
G LOC497940 similar to RIKEN cDNA 2810408A11 JBrowse link 10 56,506,834 56,511,716 RGD:1600115
G Mastl microtubule associated serine/threonine kinase-like JBrowse link 17 89,839,562 89,875,855 RGD:1624291
RGD:1600115
G Myoz1 myozenin 1 JBrowse link 15 4,077,066 4,084,306 RGD:1600115
G Phactr1 phosphatase and actin regulator 1 JBrowse link 17 23,245,423 23,761,207 RGD:1600115
G Phactr2 phosphatase and actin regulator 2 JBrowse link 1 7,352,050 7,633,991 RGD:1600115
G Phactr3 phosphatase and actin regulator 3 JBrowse link 3 173,798,542 173,871,386 RGD:1600115
G Phactr4 phosphatase and actin regulator 4 JBrowse link 5 150,533,895 150,609,423 RGD:1600115
G Ppia peptidylprolyl isomerase A JBrowse link 14 86,673,775 86,677,443 RGD:7247324
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 JBrowse link 20 3,329,677 3,344,286 RGD:1600115
G Ppp1r11 protein phosphatase 1, regulatory (inhibitor) subunit 11 JBrowse link 20 2,094,931 2,098,438 RGD:13792537
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A JBrowse link 1 87,224,683 87,232,842 RGD:1600115
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B JBrowse link 1 222,229,835 222,231,945 RGD:1600115
G Ppp1r14c protein phosphatase 1, regulatory (inhibitor) subunit 14c JBrowse link 1 39,811,314 39,923,071 RGD:1600115
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:1624291
G Ppp1r17 protein phosphatase 1, regulatory subunit 17 JBrowse link 4 86,275,130 86,292,435 RGD:1600115
G Ppp1r1a protein phosphatase 1, regulatory (inhibitor) subunit 1A JBrowse link 7 145,146,480 145,154,131 RGD:1600115
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B JBrowse link 10 86,303,727 86,312,770 RGD:1624291
RGD:1600115
G Ppp1r1c protein phosphatase 1, regulatory (inhibitor) subunit 1C JBrowse link 3 66,673,060 66,783,501 RGD:1600115
G Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 JBrowse link 11 72,748,789 73,034,683 RGD:1600115
G Ppp1r36 protein phosphatase 1, regulatory subunit 36 JBrowse link 6 99,443,753 99,464,143 RGD:1600115
G Ppp1r37 protein phosphatase 1, regulatory subunit 37 JBrowse link 1 80,439,718 80,471,527 RGD:1600115
G Ppp1r8 protein phosphatase 1, regulatory subunit 8 JBrowse link 5 151,012,035 151,029,227 RGD:1600115
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B JBrowse link 10 82,800,704 82,816,735 RGD:625568
RGD:9999389
G Ppp4r4 protein phosphatase 4, regulatory subunit 4 JBrowse link 6 127,400,585 127,497,280 RGD:1624291
RGD:13792537
G Ptn pleiotrophin JBrowse link 4 64,239,156 64,330,996 RGD:1600115
G Ptpa protein phosphatase 2 phosphatase activator JBrowse link 3 8,982,122 9,012,585 RGD:1624291
RGD:1600115
G RGD1309049 similar to RIKEN cDNA 4933415F23 JBrowse link 9 29,336,288 29,337,922 RGD:1600115
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:9590172
G Sh3rf2 SH3 domain containing ring finger 2 JBrowse link 18 36,371,041 36,471,020 RGD:1600115
G Styxl1 serine/threonine/tyrosine interacting-like 1 JBrowse link 12 23,954,563 23,987,155 RGD:1600115
RGD:1624291
G Tiprl TOR signaling pathway regulator JBrowse link 13 83,478,966 83,504,448 RGD:1624291
RGD:1600115
negative regulation of myosin-light-chain-phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:1600115
RGD:1624291
G Mprip myosin phosphatase Rho interacting protein JBrowse link 10 46,018,397 46,133,580 RGD:9685557
G Nckap1l NCK associated protein 1 like JBrowse link 7 145,068,239 145,113,507 RGD:1624291
RGD:1600115
G Rock1 Rho-associated coiled-coil containing protein kinase 1 JBrowse link 18 1,273,490 1,390,790 RGD:1600115
RGD:1624291
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 6 42,180,864 42,289,910 RGD:1600115
RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
negative regulation of protein serine/threonine phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppp1r14d protein phosphatase 1, regulatory (inhibitor) subunit 14D JBrowse link 3 111,022,920 111,037,166 RGD:1600115
RGD:1624291
negative regulation of protein tyrosine phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:13508599
G Mgat5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase JBrowse link 13 43,850,744 44,157,860 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19317
    biological regulation 13340
      regulation of molecular function 3017
        regulation of catalytic activity 2298
          regulation of hydrolase activity 1264
            regulation of phosphatase activity 178
              negative regulation of phosphatase activity 107
                negative regulation of phosphoprotein phosphatase activity 54
                  negative regulation of myosin-light-chain-phosphatase activity 6
                  negative regulation of protein serine/threonine phosphatase activity 1
                  negative regulation of protein tyrosine phosphatase activity 2
Path 2
Term Annotations click to browse term
  biological_process 19317
    biological regulation 13340
      regulation of biological process 12656
        regulation of metabolic process 6536
          regulation of cellular metabolic process 6033
            regulation of phosphorus metabolic process 1856
              regulation of phosphate metabolic process 1855
                regulation of dephosphorylation 215
                  regulation of protein dephosphorylation 136
                    regulation of phosphoprotein phosphatase activity 110
                      negative regulation of phosphoprotein phosphatase activity 54
                        negative regulation of myosin-light-chain-phosphatase activity 6
                        negative regulation of protein serine/threonine phosphatase activity 1
                        negative regulation of protein tyrosine phosphatase activity 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.