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ONTOLOGY REPORT - ANNOTATIONS


Term:connective tissue growth factor production
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Accession:GO:0032601 term browser browse the term
Definition:The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: CCN2 production;   CTGF production;   Fisp12 production;   Hcs24 production;   IGFBP8 production;   hypertrophic chondrocyte-specific gene product 24 production


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negative regulation of connective tissue growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc2a10 solute carrier family 2 member 10 ISO (PMID:16550171), (PMID:26376865) RGD PMID:16550171, PMID:26376865 NCBI chr 3:162,182,156...162,194,610
Ensembl chr 3:162,181,974...162,194,804
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positive regulation of connective tissue growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il13 interleukin 13 IDA RGD PMID:21804025 RGD:5684373 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 IMP PMID:28679962 ARUK-UCL PMID:28679962 RGD:13601991 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    multicellular organismal process 9068
      cytokine production 838
        connective tissue growth factor production 3
          negative regulation of connective tissue growth factor production 1
          positive regulation of connective tissue growth factor production 2
          regulation of connective tissue growth factor production + 3
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          gene expression 6294
            cytokine production 838
              connective tissue growth factor production 3
                negative regulation of connective tissue growth factor production 1
                positive regulation of connective tissue growth factor production 2
                regulation of connective tissue growth factor production + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.