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ONTOLOGY REPORT - ANNOTATIONS


Term:chemokine production
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Accession:GO:0032602 term browser browse the term
Definition:The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
Synonyms:exact_synonym: chemokine anabolism;   chemokine biosynthesis;   chemokine formation;   chemokine synthesis
 narrow_synonym: chemokine biosynthetic process;   chemokine secretion
 alt_id: GO:0042033;   GO:0090195


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chemokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator ISO
IBA
(MGI:MGI:4430981|PMID:19923453)
PMID:21873635
RGD PMID:19923453, PMID:21873635 MGI:MGI:4430981, RGD:13792537 NCBI chr20:11,365,630...11,380,636
Ensembl chr20:11,365,697...11,380,631
JBrowse link
G Ext1 exostosin glycosyltransferase 1 ISO (MGI:MGI:5544678|PMID:23733868) RGD PMID:23733868 MGI:MGI:5544678 NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068
JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO
ISS
(MGI:MGI:3848267|PMID:19494303)
GO_REF:0000024
(PMID:19494303), (PMID:21501162)
RGD
UniProt
PMID:19494303, PMID:21501162 GO_REF:0000024, MGI:MGI:3848267 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
chemokine (C-C motif) ligand 11 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcr3 C-X-C motif chemokine receptor 3 ISO
ISS
(PMID:12782716)
GO_REF:0000024
RGD
UniProt
PMID:12782716 GO_REF:0000024 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Tnfsf4 TNF superfamily member 4 ISO (MGI:MGI:4942253|PMID:12355440) RGD PMID:12355440 MGI:MGI:4942253 NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
JBrowse link
chemokine (C-C motif) ligand 5 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator ISO MGI:MGI:3706236 (MGI:MGI:5435130|PMID:22513871) RGD PMID:22513871 MGI:MGI:5435130 NCBI chr 8:116,318,963...116,322,181
Ensembl chr 8:116,318,963...116,322,181
JBrowse link
fractalkine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103694380 tumor necrosis factor-like IDA PMID:12729461 ARUK-UCL PMID:12729461 RGD:13673777 NCBI chr20:4,855,792...4,858,447
Ensembl chr20:4,855,829...4,858,447
JBrowse link
G Tnf tumor necrosis factor IDA PMID:12729461 ARUK-UCL PMID:12729461 RGD:13673777 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
macrophage inflammatory protein-1 alpha production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO MGI:MGI:3529594 (MGI:MGI:3839525|PMID:19139201) RGD PMID:19139201 MGI:MGI:3839525 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
negative regulation of chemokine (C-C motif) ligand 4 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 IEA
ISO
GO_REF:0000107
(MGI:MGI:5908771|PMID:27074721)
Ensembl
RGD
PMID:27074721 GO_REF:0000107, MGI:MGI:5908771 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
negative regulation of chemokine (C-C motif) ligand 5 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 IEA
ISO
GO_REF:0000107
(MGI:MGI:5908771|PMID:27074721)
Ensembl
RGD
PMID:27074721 GO_REF:0000107, MGI:MGI:5908771 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 ISO (PMID:23399697) RGD PMID:23399697 NCBI chr 5:156,855,105...156,864,517
Ensembl chr 5:156,850,206...156,864,517
JBrowse link
G Sirpa signal-regulatory protein alpha ISO
IEA
(MGI:MGI:3760575|PMID:17954568)
GO_REF:0000107
RGD
Ensembl
PMID:17954568 GO_REF:0000107, MGI:MGI:3760575 NCBI chr 3:122,113,735...122,152,478
Ensembl chr 3:122,114,108...122,152,477
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 ISO (PMID:19412184) RGD PMID:19412184 NCBI chr18:40,555,106...40,572,569
Ensembl chr18:40,555,106...40,572,241
JBrowse link
negative regulation of chemokine (C-X-C motif) ligand 2 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klf4 Kruppel like factor 4 ISO (PMID:20551324) RGD PMID:20551324 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 IMP PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590
JBrowse link
negative regulation of chemokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed ISO (PMID:12223522) RGD PMID:12223522 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Epha2 Eph receptor A2 ISO MGI:MGI:3040415 (MGI:MGI:3847147|PMID:19443703) RGD PMID:19443703 MGI:MGI:3847147 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206
JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO (PMID:19865078) RGD PMID:19865078 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Il6 interleukin 6 ISO MGI:MGI:1857197 (MGI:MGI:2673020|PMID:12925700) RGD PMID:12925700 MGI:MGI:2673020 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lgals9 galectin 9 ISO (PMID:25754930) RGD PMID:25754930 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 ISO (PMID:19380766) RGD PMID:19380766 NCBI chr 1:73,393,854...73,399,448
Ensembl chr 1:73,393,850...73,399,579
JBrowse link
G Sigirr single Ig and TIR domain containing ISO
ISS
(MGI:MGI:2673012|PMID:12925853)
GO_REF:0000024
RGD
HGNC-UCL
PMID:12925853 GO_REF:0000024, MGI:MGI:2673012 NCBI chr 1:213,898,395...213,907,697
Ensembl chr 1:213,898,401...213,907,144
JBrowse link
G Slc37a4 solute carrier family 37 member 4 ISO MGI:MGI:3046091 (MGI:MGI:3695950|PMID:16891306) RGD PMID:16891306 MGI:MGI:3695950 NCBI chr 8:48,716,914...48,723,024
Ensembl chr 8:48,716,939...48,723,024
JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit IMP RGD PMID:23192652 RGD:9586745 NCBI chr10:67,325,101...67,371,588
Ensembl chr10:67,325,347...67,369,668
JBrowse link
negative regulation of IP-10 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lilrb4 leukocyte immunoglobulin like receptor B4 ISO (PMID:19380766) RGD PMID:19380766 NCBI chr 1:73,393,854...73,399,448
Ensembl chr 1:73,393,850...73,399,579
JBrowse link
negative regulation of macrophage inflammatory protein 1 alpha production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 IEA
ISO
GO_REF:0000107
(MGI:MGI:5908771|PMID:27074721)
Ensembl
RGD
PMID:27074721 GO_REF:0000107, MGI:MGI:5908771 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Mefv MEFV innate immuity regulator, pyrin ISO (PMID:20041150) RGD PMID:20041150 NCBI chr10:12,045,813...12,056,229
Ensembl chr10:12,046,541...12,056,311
JBrowse link
G Sirpa signal-regulatory protein alpha ISO
IEA
(MGI:MGI:3760575|PMID:17954568)
GO_REF:0000107
RGD
Ensembl
PMID:17954568 GO_REF:0000107, MGI:MGI:3760575 NCBI chr 3:122,113,735...122,152,478
Ensembl chr 3:122,114,108...122,152,477
JBrowse link
negative regulation of monocyte chemotactic protein-1 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apod apolipoprotein D IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:18842892)
Ensembl
UniProt
RGD
PMID:18842892 GO_REF:0000024, GO_REF:0000107 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G C1qtnf3 C1q and TNF related 3 ISO (PMID:20739398) RGD PMID:20739398 NCBI chr 2:60,920,160...60,942,586
Ensembl chr 2:60,920,257...60,942,500
JBrowse link
G Cd24 CD24 molecule ISO (MGI:MGI:5913663|PMID:19264983) RGD PMID:19264983 MGI:MGI:5913663 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Erbin erbb2 interacting protein ISO UniProtKB:Q8K3Z0 (MGI:MGI:5640951|PMID:16203728) RGD PMID:16203728 MGI:MGI:5640951 NCBI chr 2:33,880,860...33,952,806
Ensembl chr 2:33,881,024...33,920,837
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO
ISS
(PMID:18962899)
GO_REF:0000024
(MGI:MGI:5009376|PMID:18962899)
RGD
BHF-UCL
PMID:18962899 GO_REF:0000024, MGI:MGI:5009376 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IEA
ISO
GO_REF:0000107
(MGI:MGI:5707586|PMID:18972444)
Ensembl
RGD
PMID:18972444 GO_REF:0000107, MGI:MGI:5707586 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Socs5 suppressor of cytokine signaling 5 ISO (MGI:MGI:5659826|PMID:24255059) RGD PMID:24255059 MGI:MGI:5659826 NCBI chr 6:10,671,311...10,705,610
Ensembl chr 6:10,674,371...10,704,977
JBrowse link
positive regulation of chemokine (C-C motif) ligand 1 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tslp thymic stromal lymphopoietin ISO (PMID:17242164) RGD PMID:17242164 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
positive regulation of chemokine (C-C motif) ligand 20 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trim32 tripartite motif-containing 32 ISO (MGI:MGI:4453084|PMID:20054338) RGD PMID:20054338 MGI:MGI:4453084 NCBI chr 5:81,431,554...81,449,023
Ensembl chr 5:81,431,600...81,442,451
JBrowse link
positive regulation of chemokine (C-C motif) ligand 5 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 ISO (PMID:24696163) RGD PMID:24696163 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716
JBrowse link
G Defb25 defensin beta 25 ISO
IBA
(PMID:24955228)
PMID:21873635
RGD PMID:24955228, PMID:21873635 RGD:13792537 NCBI chr 3:148,103,643...148,104,483
Ensembl chr 3:148,103,643...148,104,483
JBrowse link
G Mavs mitochondrial antiviral signaling protein ISO (PMID:16127453) RGD PMID:16127453 NCBI chr 3:123,776,147...123,790,572
Ensembl chr 3:123,776,181...123,790,567
JBrowse link
G Mcoln2 mucolipin 2 ISO MGI:MGI:5881907 (MGI:MGI:5881894|PMID:26432893) RGD PMID:26432893 MGI:MGI:5881894 NCBI chr 2:252,018,594...252,068,209
Ensembl chr 2:252,018,597...252,068,271
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 ISO (PMID:19412184)
(MGI:MGI:3778252|PMID:18297073)
RGD PMID:18297073, PMID:19412184 MGI:MGI:3778252 NCBI chr18:40,555,106...40,572,569
Ensembl chr18:40,555,106...40,572,241
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO (MGI:MGI:5440106|PMID:23021218) RGD PMID:23021218 MGI:MGI:5440106 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
positive regulation of chemokine (C-X-C motif) ligand 1 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A ISO
IEA
(PMID:21350122)
GO_REF:0000107
(MGI:MGI:4412246|PMID:18025225)
RGD
Ensembl
PMID:18025225, PMID:21350122 GO_REF:0000107, MGI:MGI:4412246 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il17f interleukin 17F ISO
IEA
(PMID:21350122)
GO_REF:0000107
RGD
Ensembl
PMID:21350122 GO_REF:0000107 NCBI chr 9:26,885,702...26,897,219
Ensembl chr 9:26,885,708...26,897,219
JBrowse link
G Il17ra interleukin 17 receptor A ISO (PMID:21350122) RGD PMID:21350122 NCBI chr 4:152,995,865...153,018,394
Ensembl chr 4:152,995,865...153,018,394
JBrowse link
G Tirap TIR domain containing adaptor protein ISO (MGI:MGI:3713420|PMID:16301656) RGD PMID:16301656 MGI:MGI:3713420 NCBI chr 8:36,382,029...36,399,625
Ensembl chr 8:36,385,353...36,388,224
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO (MGI:MGI:5440106|PMID:23021218) RGD PMID:23021218 MGI:MGI:5440106 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
positive regulation of chemokine (C-X-C motif) ligand 2 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd74 CD74 molecule ISO
ISS
(MGI:MGI:4943655|PMID:19413900)
GO_REF:0000024
RGD
BHF-UCL
PMID:19413900 GO_REF:0000024, MGI:MGI:4943655 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Defb25 defensin beta 25 ISO (PMID:24955228) RGD PMID:24955228 NCBI chr 3:148,103,643...148,104,483
Ensembl chr 3:148,103,643...148,104,483
JBrowse link
G Hdac1 histone deacetylase 1 IMP RGD PMID:22772764 RGD:9590127 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hmgb1 high mobility group box 1 ISO (PMID:26961863) RGD PMID:26961863 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Lpl lipoprotein lipase ISO RNAcentral:URS00005C83FD_10090 (MGI:MGI:6282927|PMID:22963823) RGD PMID:22963823 MGI:MGI:6282927 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrp1 LDL receptor related protein 1 IMP RGD PMID:21290408 RGD:13800525 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Mbp myelin basic protein ISO
IEA
(PMID:22524708)
GO_REF:0000107
RGD
Ensembl
PMID:22524708 GO_REF:0000107 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mcoln2 mucolipin 2 ISO MGI:MGI:5881907 (MGI:MGI:5881894|PMID:26432893) RGD PMID:26432893 MGI:MGI:5881894 NCBI chr 2:252,018,594...252,068,209
Ensembl chr 2:252,018,597...252,068,271
JBrowse link
G Mif macrophage migration inhibitory factor ISO (MGI:MGI:3773489|PMID:18056708) RGD PMID:18056708 MGI:MGI:3773489 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Postn periostin IMP RGD PMID:24260297 RGD:10041046 NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087
JBrowse link
G Tirap TIR domain containing adaptor protein ISO (MGI:MGI:3713420|PMID:16301656) RGD PMID:16301656 MGI:MGI:3713420 NCBI chr 8:36,382,029...36,399,625
Ensembl chr 8:36,385,353...36,388,224
JBrowse link
G Tlr4 toll-like receptor 4 ISO
IEA
(PMID:21329689)
GO_REF:0000107
RGD
Ensembl
PMID:21329689 GO_REF:0000107 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:20551324) RGD PMID:20551324 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
positive regulation of chemokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO
IEA
(PMID:16034137)
GO_REF:0000107
RGD
Ensembl
PMID:16034137 GO_REF:0000107 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adora2b adenosine A2B receptor ISO
IEA
MGI:MGI:3773754 (MGI:MGI:3806198|PMID:18559975)
GO_REF:0000107
RGD
Ensembl
PMID:18559975 GO_REF:0000107, MGI:MGI:3806198 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO UniProtKB:P05067 (MGI:MGI:5424311|PMID:22406537) RGD PMID:22406537 MGI:MGI:5424311 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Aif1 allograft inflammatory factor 1 ISO (PMID:24796669) RGD PMID:24796669 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B ISO (PMID:18067895) RGD PMID:18067895 NCBI chr10:55,773,748...55,783,489
Ensembl chr10:55,774,006...55,783,489
JBrowse link
G App amyloid beta precursor protein ISO UniProtKB:Q62151 (PMID:22406537) RGD PMID:22406537 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G C5 complement C5 ISO (PMID:14566334) RGD PMID:14566334 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Cd74 CD74 molecule ISO (PMID:19423618) RGD PMID:19423618 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Chia chitinase, acidic ISO
ISS
(PMID:18824549)
GO_REF:0000024
RGD
UniProt
PMID:18824549 GO_REF:0000024 NCBI chr 2:208,750,348...208,797,388
Ensembl chr 2:208,749,996...208,797,402
JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO (PMID:20829061) RGD PMID:20829061 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Defb25 defensin beta 25 ISO (PMID:24955228) RGD PMID:24955228 NCBI chr 3:148,103,643...148,104,483
Ensembl chr 3:148,103,643...148,104,483
JBrowse link
G Defb43 defensin beta 43 ISO (PMID:26649771) RGD PMID:26649771 NCBI chr15:46,196,771...46,201,271
Ensembl chr15:46,196,771...46,201,271
JBrowse link
G Egr1 early growth response 1 ISO
ISS
(MGI:MGI:1928025|PMID:11100120)
GO_REF:0000024
RGD
UniProt
PMID:11100120 GO_REF:0000024, MGI:MGI:1928025 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 ISO
ISS
(MGI:MGI:5487533|PMID:20038207)
GO_REF:0000024
RGD
UniProt
PMID:20038207 GO_REF:0000024, MGI:MGI:5487533 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201
JBrowse link
G Ffar2 free fatty acid receptor 2 ISO
ISS
(MGI:MGI:5575446|PMID:23665276)
GO_REF:0000024
RGD
UniProt
PMID:23665276 GO_REF:0000024, MGI:MGI:5575446 NCBI chr 1:89,268,197...89,271,942
Ensembl chr 1:89,268,938...89,269,930
JBrowse link
G Ffar3 free fatty acid receptor 3 ISO
ISS
(MGI:MGI:5575446|PMID:23665276)
GO_REF:0000024
RGD
UniProt
PMID:23665276 GO_REF:0000024, MGI:MGI:5575446 NCBI chr 1:89,302,035...89,304,064
Ensembl chr 1:89,302,039...89,303,968
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO UniProtKB:O08573 (MGI:MGI:4839671|PMID:20937702) RGD PMID:20937702 MGI:MGI:4839671 NCBI chr10:31,561,838...31,590,624
Ensembl chr10:31,561,895...31,588,943
JBrowse link
G Ifng interferon gamma ISO MGI:MGI:1857184 (MGI:MGI:2673020|PMID:12925700)
(PMID:19423618)
RGD PMID:12925700, PMID:19423618 MGI:MGI:2673020 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il16 interleukin 16 ISO (MGI:MGI:6414686|PMID:30089723) RGD PMID:30089723 MGI:MGI:6414686 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912
JBrowse link
G Il18 interleukin 18 IMP RGD PMID:19497959 RGD:4889403 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta ISO (MGI:MGI:2673020|PMID:12925700) RGD PMID:12925700 MGI:MGI:2673020 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 ISO (MGI:MGI:4430159|PMID:19841166) RGD PMID:19841166 MGI:MGI:4430159 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il33 interleukin 33 ISO (MGI:MGI:4430159|PMID:19841166)
(PMID:19841166)
RGD PMID:19841166 MGI:MGI:4430159 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il4 interleukin 4 ISO
IBA
(MGI:MGI:85739|PMID:9013979)
PMID:21873635
RGD PMID:9013979, PMID:21873635 MGI:MGI:85739, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor ISO (MGI:MGI:4430159|PMID:19841166) RGD PMID:19841166 MGI:MGI:4430159 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 ISO (PMID:10510402) RGD PMID:10510402 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor ISO (PMID:10510402) RGD PMID:10510402 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Il7 interleukin 7 IEA
ISO
GO_REF:0000107
(PMID:11418668)
Ensembl
RGD
PMID:11418668 GO_REF:0000107 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
JBrowse link
G Lbp lipopolysaccharide binding protein ISO
IEA
MGI:MGI:1857975 (MGI:MGI:3719540|PMID:12055258)
GO_REF:0000107
RGD
Ensembl
PMID:12055258 GO_REF:0000107, MGI:MGI:3719540 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Lgals9 galectin 9 ISO UniProtKB:Q8VIM0 (MGI:MGI:4839671|PMID:20937702) RGD PMID:20937702 MGI:MGI:4839671 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G Lpl lipoprotein lipase ISO (PMID:25149060) RGD PMID:25149060 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP Rat GRO/CINC-1 RGD PMID:16942465 RGD:2304233 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mcoln2 mucolipin 2 ISO MGI:MGI:5881907 (MGI:MGI:5881894|PMID:26432893) RGD PMID:26432893 MGI:MGI:5881894 NCBI chr 2:252,018,594...252,068,209
Ensembl chr 2:252,018,597...252,068,271
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ISO MGI:MGI:2147032 (MGI:MGI:2669022|PMID:12855817) RGD PMID:12855817 MGI:MGI:2669022 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G P2ry2 purinergic receptor P2Y2 IDA RGD PMID:17947675 RGD:2316680 NCBI chr 1:166,031,228...166,045,423
Ensembl chr 1:166,031,272...166,037,424
JBrowse link
G Pycard PYD and CARD domain containing ISO (MGI:MGI:5448518|PMID:21487011)
(PMID:21487011)
RGD PMID:21487011 MGI:MGI:5448518 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 ISO MGI:MGI:2660793 (MGI:MGI:2176422|PMID:11894098) RGD PMID:11894098 MGI:MGI:2176422 NCBI chr 5:29,838,713...29,870,390
Ensembl chr 5:29,838,747...29,870,735
JBrowse link
G Selenok selenoprotein K ISO (MGI:MGI:4939970|PMID:21220695) RGD PMID:21220695 MGI:MGI:4939970 NCBI chr16:6,035,926...6,044,240
Ensembl chr16:6,035,926...6,044,239
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 ISO MGI:MGI:108005|MGI:MGI:3029019 (MGI:MGI:2669022|PMID:12855817) RGD PMID:12855817 MGI:MGI:2669022 NCBI chr 9:10,780,185...10,790,280 JBrowse link
G Tlr2 toll-like receptor 2 ISO MGI:MGI:2178675 (MGI:MGI:3611539|PMID:16239543)
(PMID:19740627)
RGD PMID:16239543, PMID:19740627 MGI:MGI:3611539 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr3 toll-like receptor 3 ISO MGI:MGI:3690535 (MGI:MGI:2669022|PMID:12855817)
(PMID:19740627)
RGD PMID:12855817, PMID:19740627 MGI:MGI:2669022 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tlr4 toll-like receptor 4 ISO (PMID:19740627)
(MGI:MGI:4456948|PMID:15356140)
RGD PMID:15356140, PMID:19740627 MGI:MGI:4456948 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr7 toll-like receptor 7 ISO (PMID:19740627) RGD PMID:19740627 NCBI chr  X:28,486,836...28,513,004
Ensembl chr  X:28,486,869...28,512,957
JBrowse link
G Tlr9 toll-like receptor 9 ISO (PMID:19740627) RGD PMID:19740627 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:10490959) RGD PMID:10490959 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tslp thymic stromal lymphopoietin ISO (PMID:11418668) RGD PMID:11418668 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
G Wnt5a Wnt family member 5A ISO (PMID:19520808) RGD PMID:19520808 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
positive regulation of IP-10 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mavs mitochondrial antiviral signaling protein ISO (PMID:16127453) RGD PMID:16127453 NCBI chr 3:123,776,147...123,790,572
Ensembl chr 3:123,776,181...123,790,567
JBrowse link
positive regulation of macrophage inflammatory protein 1 alpha production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 IDA PMID:10952726 UniProt PMID:10952726 RGD:10054071 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Mcoln2 mucolipin 2 ISO MGI:MGI:5881907 (MGI:MGI:5881894|PMID:26432893) RGD PMID:26432893 MGI:MGI:5881894 NCBI chr 2:252,018,594...252,068,209
Ensembl chr 2:252,018,597...252,068,271
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO (MGI:MGI:5440106|PMID:23021218) RGD PMID:23021218 MGI:MGI:5440106 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
positive regulation of monocyte chemotactic protein-1 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO
ISS
(PMID:19524870)
GO_REF:0000024
RGD
UniProt
PMID:19524870 GO_REF:0000024 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO
IEA
UniProtKB:P02638 (MGI:MGI:5605404|PMID:24995813)
GO_REF:0000107
RGD
Ensembl
PMID:24995813 GO_REF:0000107, MGI:MGI:5605404 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Cd84 CD84 molecule ISO (MGI:MGI:5700297|PMID:20628063) RGD PMID:20628063 MGI:MGI:5700297 NCBI chr13:90,241,369...90,283,625
Ensembl chr13:90,244,681...90,277,865
JBrowse link
G Clec7a C-type lectin domain containing 7A ISO (PMID:25251945) RGD PMID:25251945 NCBI chr 4:163,216,152...163,227,367
Ensembl chr 4:163,216,163...163,227,334
JBrowse link
G Hmgb1 high mobility group box 1 ISO (MGI:MGI:5913663|PMID:19264983) RGD PMID:19264983 MGI:MGI:5913663 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Il1a interleukin 1 alpha ISO (MGI:MGI:5468848|PMID:23395675) RGD PMID:23395675 MGI:MGI:5468848 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta IEA
ISO
GO_REF:0000107
(PMID:19524870)
Ensembl
RGD
PMID:19524870 GO_REF:0000107 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Lgals9 galectin 9 ISO (PMID:24465902) RGD PMID:24465902 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G Mcoln2 mucolipin 2 ISO MGI:MGI:5881907 (MGI:MGI:5881894|PMID:26432893) RGD PMID:26432893 MGI:MGI:5881894 NCBI chr 2:252,018,594...252,068,209
Ensembl chr 2:252,018,597...252,068,271
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO (MGI:MGI:5640951|PMID:16203728) RGD PMID:16203728 MGI:MGI:5640951 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Selenok selenoprotein K IEA
ISO
GO_REF:0000107
(MGI:MGI:4939970|PMID:21220695)
Ensembl
RGD
PMID:21220695 GO_REF:0000107, MGI:MGI:4939970 NCBI chr16:6,035,926...6,044,240
Ensembl chr16:6,035,926...6,044,239
JBrowse link
G Syk spleen associated tyrosine kinase IEA
ISO
GO_REF:0000107
(PMID:25251945)
Ensembl
RGD
PMID:25251945 GO_REF:0000107 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO (MGI:MGI:5440106|PMID:23021218) RGD PMID:23021218 MGI:MGI:5440106 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (PMID:20007935) RGD PMID:20007935 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
regulation of chemokine (C-X-C motif) ligand 1 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88, innate immune signal transduction adaptor ISO MGI:MGI:4421295 (MGI:MGI:5637650|PMID:25084278) RGD PMID:25084278 MGI:MGI:5637650 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
regulation of chemokine (C-X-C motif) ligand 2 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 ISO
ISS
(PMID:21501162)
GO_REF:0000024
RGD
UniProt
PMID:21501162 GO_REF:0000024 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Foxp1 forkhead box P1 ISO (PMID:18799727) RGD PMID:18799727 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G Mcoln2 mucolipin 2 ISO MGI:MGI:5881907 (MGI:MGI:5881894|PMID:26432893) RGD PMID:26432893 MGI:MGI:5881894 NCBI chr 2:252,018,594...252,068,209
Ensembl chr 2:252,018,597...252,068,271
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ISO MGI:MGI:4421295 (MGI:MGI:5637650|PMID:25084278) RGD PMID:25084278 MGI:MGI:5637650 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
regulation of chemokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr1 atypical chemokine receptor 1 ISO MGI:MGI:1888977 (MGI:MGI:4819434|PMID:20643340) RGD PMID:20643340 MGI:MGI:4819434 NCBI chr13:91,827,310...91,828,875 JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 ISO MGI:MGI:4819800 (MGI:MGI:4819434|PMID:20643340) RGD PMID:20643340 MGI:MGI:4819434 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor ISO MGI:MGI:2660811 (MGI:MGI:4819434|PMID:20643340) RGD PMID:20643340 MGI:MGI:4819434 NCBI chr 5:137,268,412...137,282,032
Ensembl chr 5:137,269,480...137,281,298
JBrowse link
G Snai2 snail family transcriptional repressor 2 ISO (PMID:21182836) RGD PMID:21182836 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Zfpm1 zinc finger protein, multitype 1 ISO MGI:MGI:4421151 (MGI:MGI:4819434|PMID:20643340) RGD PMID:20643340 MGI:MGI:4819434 NCBI chr19:55,094,585...55,150,994
Ensembl chr19:55,094,585...55,150,686
JBrowse link
regulation of macrophage inflammatory protein 1 alpha production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 ISO ComplexPortal:CPX-1120 (MGI:MGI:6150565|PMID:29518356) RGD PMID:29518356 MGI:MGI:6150565 NCBI chr 9:14,611,541...14,618,076
Ensembl chr 9:14,611,561...14,618,013
JBrowse link
regulation of monocyte chemotactic protein-1 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf18 TNF superfamily member 18 NOT ISO (MGI:MGI:5551556|PMID:24107315) RGD PMID:24107315 MGI:MGI:5551556 NCBI chr13:79,378,412...79,388,687
Ensembl chr13:79,378,733...79,388,498
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    multicellular organismal process 9068
      cytokine production 838
        chemokine production 103
          IP-10 production + 2
          chemokine (C-C motif) ligand 1 production + 1
          chemokine (C-C motif) ligand 11 production 2
          chemokine (C-C motif) ligand 17 production 0
          chemokine (C-C motif) ligand 19 production 0
          chemokine (C-C motif) ligand 20 production + 1
          chemokine (C-C motif) ligand 21 production 0
          chemokine (C-C motif) ligand 22 production 0
          chemokine (C-C motif) ligand 4 production + 1
          chemokine (C-C motif) ligand 5 production + 10
          chemokine (C-C motif) ligand 6 production + 0
          chemokine (C-X-C motif) ligand 1 production + 6
          chemokine (C-X-C motif) ligand 12 production 0
          chemokine (C-X-C motif) ligand 13 production 0
          chemokine (C-X-C motif) ligand 16 production 0
          chemokine (C-X-C motif) ligand 2 production + 18
          chemokine (C-X-C motif) ligand 9 production + 0
          fractalkine production + 2
          macrophage inflammatory protein-1 alpha production + 8
          macrophage inflammatory protein-1 gamma production + 0
          monocyte chemotactic protein-1 production + 22
          negative regulation of chemokine production + 23
          positive regulation of chemokine production + 69
          regulation of chemokine production + 97
          thymic stromal lymphopoietin production 0
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          protein metabolic process 6264
            cytokine metabolic process 111
              chemokine metabolic process 106
                chemokine production 103
                  IP-10 production + 2
                  chemokine (C-C motif) ligand 1 production + 1
                  chemokine (C-C motif) ligand 11 production 2
                  chemokine (C-C motif) ligand 17 production 0
                  chemokine (C-C motif) ligand 19 production 0
                  chemokine (C-C motif) ligand 20 production + 1
                  chemokine (C-C motif) ligand 21 production 0
                  chemokine (C-C motif) ligand 22 production 0
                  chemokine (C-C motif) ligand 4 production + 1
                  chemokine (C-C motif) ligand 5 production + 10
                  chemokine (C-C motif) ligand 6 production + 0
                  chemokine (C-X-C motif) ligand 1 production + 6
                  chemokine (C-X-C motif) ligand 12 production 0
                  chemokine (C-X-C motif) ligand 13 production 0
                  chemokine (C-X-C motif) ligand 16 production 0
                  chemokine (C-X-C motif) ligand 2 production + 18
                  chemokine (C-X-C motif) ligand 9 production + 0
                  fractalkine production + 2
                  macrophage inflammatory protein-1 alpha production + 8
                  macrophage inflammatory protein-1 gamma production + 0
                  monocyte chemotactic protein-1 production + 22
                  negative regulation of chemokine production + 23
                  positive regulation of chemokine production + 69
                  regulation of chemokine production + 97
                  thymic stromal lymphopoietin production 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.