ONTOLOGY REPORT - ANNOTATIONS


Term:chemokine production
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Accession:GO:0032602 term browser browse the term
Definition:The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


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chemokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aire autoimmune regulator JBrowse link 20 11,365,630 11,380,636 RGD:1624291
RGD:13792537
chemokine (C-C motif) ligand 11 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cxcr3 C-X-C motif chemokine receptor 3 JBrowse link X 71,614,346 71,616,997 RGD:1624291
RGD:1600115
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
RGD:1600115
chemokine (C-C motif) ligand 2 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
RGD:1600115
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
G Mcoln2 mucolipin 2 JBrowse link 2 252,018,594 252,068,209 RGD:1624291
RGD:1600115
chemokine (C-C motif) ligand 5 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator JBrowse link 8 116,318,963 116,322,181 RGD:1624291
RGD:1600115
chemokine secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
RGD:1600115
macrophage inflammatory protein-1 alpha production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
negative regulation of chemokine (C-C motif) ligand 4 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1600115
RGD:1624291
negative regulation of chemokine (C-C motif) ligand 5 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1600115
RGD:1624291
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 JBrowse link 5 156,855,105 156,864,517 RGD:1624291
RGD:1600115
G Sirpa signal-regulatory protein alpha JBrowse link 3 122,113,735 122,152,478 RGD:1624291
G Ticam2 toll-like receptor adaptor molecule 2 JBrowse link 18 40,555,106 40,572,569 RGD:1624291
negative regulation of chemokine (C-X-C motif) ligand 2 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Klf4 Kruppel like factor 4 JBrowse link 5 72,283,311 72,287,669 RGD:1624291
RGD:1600115
G Map2k5 mitogen activated protein kinase kinase 5 JBrowse link 8 68,055,976 68,282,656 RGD:8553940
negative regulation of chemokine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:1624291
RGD:1600115
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
RGD:1600115
G Sigirr single Ig and TIR domain containing JBrowse link 1 213,898,395 213,907,697 RGD:1624291
RGD:1600115
negative regulation of chemokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epha2 Eph receptor A2 JBrowse link 5 159,845,773 159,874,203 RGD:1624291
RGD:1600115
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Slc37a4 solute carrier family 37 member 4 JBrowse link 8 48,716,914 48,723,024 RGD:1624291
RGD:1600115
G Suz12 SUZ12 polycomb repressive complex 2 subunit JBrowse link 10 67,325,101 67,371,588 RGD:9586745
negative regulation of chemokine secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
RGD:1600115
negative regulation of macrophage inflammatory protein 1 alpha production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1600115
RGD:1624291
G Mefv MEFV innate immuity regulator, pyrin JBrowse link 10 12,045,813 12,056,229 RGD:1624291
G Sirpa signal-regulatory protein alpha JBrowse link 3 122,113,735 122,152,478 RGD:1624291
negative regulation of monocyte chemotactic protein-1 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apod apolipoprotein D JBrowse link 11 72,705,204 72,726,263 RGD:1600115
RGD:1624291
G C1qtnf3 C1q and TNF related 3 JBrowse link 2 60,920,160 60,942,586 RGD:1624291
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1600115
RGD:1624291
G Erbin erbb2 interacting protein JBrowse link 2 33,880,860 33,952,806 RGD:1624291
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:1624291
RGD:1600115
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:1600115
RGD:1624291
G Socs5 suppressor of cytokine signaling 5 JBrowse link 6 10,671,311 10,705,610 RGD:1624291
RGD:1600115
positive regulation of chemokine (C-C motif) ligand 1 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tslp thymic stromal lymphopoietin JBrowse link 18 25,613,601 25,618,066 RGD:1624291
positive regulation of chemokine (C-C motif) ligand 2 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:1600115
RGD:1624291
G Lrp1 LDL receptor related protein 1 JBrowse link 7 70,846,313 70,927,028 RGD:13800525
G Mbp myelin basic protein JBrowse link 18 79,326,738 79,437,310 RGD:1600115
RGD:1624291
G Postn periostin JBrowse link 2 143,656,820 143,688,087 RGD:10041046
positive regulation of chemokine (C-C motif) ligand 20 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trim32 tripartite motif-containing 32 JBrowse link 5 81,431,554 81,449,023 RGD:1624291
RGD:1600115
positive regulation of chemokine (C-C motif) ligand 5 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:1624291
RGD:1600115
G Mavs mitochondrial antiviral signaling protein JBrowse link 3 123,776,147 123,790,572 RGD:1624291
G Mcoln2 mucolipin 2 JBrowse link 2 252,018,594 252,068,209 RGD:1624291
RGD:1600115
G Ticam2 toll-like receptor adaptor molecule 2 JBrowse link 18 40,555,106 40,572,569 RGD:1624291
RGD:1600115
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
RGD:1600115
positive regulation of chemokine (C-X-C motif) ligand 1 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tirap TIR domain containing adaptor protein JBrowse link 8 36,382,029 36,399,625 RGD:1624291
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
RGD:1600115
positive regulation of chemokine (C-X-C motif) ligand 2 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
RGD:1600115
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:9590127
G Mcoln2 mucolipin 2 JBrowse link 2 252,018,594 252,068,209 RGD:1624291
RGD:1600115
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1624291
G Tirap TIR domain containing adaptor protein JBrowse link 8 36,382,029 36,399,625 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
positive regulation of chemokine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1600115
RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1600115
RGD:1624291
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:1600115
RGD:1624291
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
RGD:1600115
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1624291
RGD:1600115
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:1624291
RGD:1600115
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:1624291
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1624291
RGD:1600115
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1600115
RGD:1624291
positive regulation of chemokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam17 ADAM metallopeptidase domain 17 JBrowse link 6 43,400,525 43,448,280 RGD:1624291
RGD:1600115
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:1624291
RGD:1600115
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 JBrowse link 6 1,428,845 1,466,193 RGD:1624291
RGD:1600115
G Ffar2 free fatty acid receptor 2 JBrowse link 1 89,268,197 89,271,942 RGD:1624291
RGD:1600115
G Ffar3 free fatty acid receptor 3 JBrowse link 1 89,302,035 89,304,064 RGD:1624291
RGD:1600115
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:4889403
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:1624291
G Il7 interleukin 7 JBrowse link 2 96,427,884 96,474,979 RGD:1600115
RGD:1624291
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:1624291
RGD:1600115
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:2304233
G Mcoln2 mucolipin 2 JBrowse link 2 252,018,594 252,068,209 RGD:1624291
G P2ry2 purinergic receptor P2Y2 JBrowse link 1 166,031,228 166,045,423 RGD:2316680
G Ripk2 receptor-interacting serine-threonine kinase 2 JBrowse link 5 29,838,713 29,870,390 RGD:1624291
RGD:1600115
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1624291
RGD:1600115
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:1600115
G Tlr7 toll-like receptor 7 JBrowse link X 28,486,836 28,513,004 RGD:1624291
RGD:1600115
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Tslp thymic stromal lymphopoietin JBrowse link 18 25,613,601 25,618,066 RGD:1624291
positive regulation of chemokine secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:1600115
RGD:1624291
G Alox15b arachidonate 15-lipoxygenase, type B JBrowse link 10 55,773,748 55,783,489 RGD:1600115
RGD:1624291
G C5 complement C5 JBrowse link 3
3
14,049,993
14,206,466
14,113,931
14,229,141
RGD:1624291
RGD:1600115
G Chia chitinase, acidic JBrowse link 2 208,750,348 208,797,388 RGD:1624291
RGD:1600115
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:1600115
RGD:1624291
G Il1rl1 interleukin 1 receptor-like 1 JBrowse link 9 47,133,483 47,184,316 RGD:1624291
RGD:1600115
G Il33 interleukin 33 JBrowse link 1 248,112,611 248,147,030 RGD:1624291
RGD:1600115
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:1624291
G LOC103694380 tumor necrosis factor-like JBrowse link 20 4,855,792 4,858,447 RGD:13673777
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:1624291
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
RGD:1600115
G Selenok selenoprotein K JBrowse link 16 6,035,926 6,044,240 RGD:1600115
RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:13673777
positive regulation of fractalkine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC103694380 tumor necrosis factor-like JBrowse link 20 4,855,792 4,858,447 RGD:13673777
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:13673777
positive regulation of IP-10 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mavs mitochondrial antiviral signaling protein JBrowse link 3 123,776,147 123,790,572 RGD:1624291
positive regulation of macrophage inflammatory protein 1 alpha production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:10054071
G Mcoln2 mucolipin 2 JBrowse link 2 252,018,594 252,068,209 RGD:1624291
RGD:1600115
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
RGD:1600115
positive regulation of monocyte chemotactic protein-1 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:1624291
RGD:1600115
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1624291
RGD:1600115
G Cd84 CD84 molecule JBrowse link 13 90,241,369 90,283,625 RGD:1624291
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Mcoln2 mucolipin 2 JBrowse link 2 252,018,594 252,068,209 RGD:1624291
RGD:1600115
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
G Selenok selenoprotein K JBrowse link 16 6,035,926 6,044,240 RGD:1600115
RGD:1624291
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
RGD:1600115
G Twist1 twist family bHLH transcription factor 1 JBrowse link 6 53,401,241 53,403,235 RGD:1624291
RGD:1600115
regulation of chemokine (C-X-C motif) ligand 1 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:1624291
RGD:1600115
regulation of chemokine (C-X-C motif) ligand 2 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:1624291
RGD:1600115
regulation of chemokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ackr1 atypical chemokine receptor 1 JBrowse link 13 91,827,310 91,828,875 RGD:1624291
G Cxcl6 C-X-C motif chemokine ligand 6 JBrowse link 14 18,860,201 18,920,839 RGD:1624291
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link 5 137,268,412 137,282,032 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
G Zfpm1 zinc finger protein, multitype 1 JBrowse link 19 55,094,585 55,150,994 RGD:1624291
RGD:1600115
regulation of macrophage inflammatory protein 1 alpha production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trem2 triggering receptor expressed on myeloid cells 2 JBrowse link 9 14,611,541 14,618,076 RGD:1624291
regulation of monocyte chemotactic protein-1 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfsf18 TNF superfamily member 18 JBrowse link 13 79,378,412 79,388,687 RGD:1624291

Term paths to the root
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Term Annotations click to browse term
  biological_process 17895
    multicellular organismal process 8519
      cytokine production 767
        chemokine production 93
          IP-10 production + 1
          chemokine (C-C motif) ligand 1 production + 1
          chemokine (C-C motif) ligand 11 production 2
          chemokine (C-C motif) ligand 17 production 0
          chemokine (C-C motif) ligand 19 production 0
          chemokine (C-C motif) ligand 20 production + 1
          chemokine (C-C motif) ligand 21 production 0
          chemokine (C-C motif) ligand 22 production 0
          chemokine (C-C motif) ligand 4 production + 1
          chemokine (C-C motif) ligand 5 production + 9
          chemokine (C-C motif) ligand 6 production + 0
          chemokine (C-X-C motif) ligand 1 production + 3
          chemokine (C-X-C motif) ligand 12 production 0
          chemokine (C-X-C motif) ligand 13 production 0
          chemokine (C-X-C motif) ligand 16 production 0
          chemokine (C-X-C motif) ligand 2 production + 15
          chemokine (C-X-C motif) ligand 9 production + 0
          chemokine biosynthetic process + 15
          chemokine secretion + 19
          fractalkine production + 2
          macrophage inflammatory protein-1 alpha production + 8
          macrophage inflammatory protein-1 gamma production + 0
          monocyte chemotactic protein-1 production + 20
          negative regulation of chemokine production + 22
          positive regulation of chemokine production + 62
          regulation of chemokine production + 88
          thymic stromal lymphopoietin production 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.