ONTOLOGY REPORT - ANNOTATIONS


Term:type I interferon production
go back to main search page
Accession:GO:0032606 term browser browse the term
Definition:The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
Synonyms:exact_synonym: type I IFN production


show annotations for term's descendants       view all columns           Sort by:
 
interferon-alpha production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Azi2 5-azacytidine induced 2 JBrowse link 8 126,411,030 126,435,581 RGD:1600115
RGD:1624291
G Irf7 interferon regulatory factor 7 JBrowse link 1 214,249,388 214,252,909 RGD:1624291
RGD:1600115
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
RGD:1600115
interferon-beta production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Irf7 interferon regulatory factor 7 JBrowse link 1 214,249,388 214,252,909 RGD:1624291
RGD:1600115
G Tmem173 transmembrane protein 173 JBrowse link 18 28,529,537 28,535,828 RGD:1600115
RGD:13792537
RGD:1624291
interferon-tau production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:1624291
negative regulation of interferon-alpha biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nmi N-myc (and STAT) interactor JBrowse link 3 37,458,891 37,480,984 RGD:1624291
negative regulation of interferon-alpha production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
RGD:1600115
G Lilrb3a leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3A JBrowse link 1 64,005,797 64,013,268 RGD:1624291
G Nlrc3 NLR family, CARD domain containing 3 JBrowse link 10 11,809,531 11,844,184 RGD:1624291
G Ptprs protein tyrosine phosphatase, receptor type, S JBrowse link 9 10,585,360 10,646,205 RGD:1600115
RGD:1624291
negative regulation of interferon-beta biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crebbp CREB binding protein JBrowse link 10 11,590,994 11,721,039 RGD:1624291
G Irf3 interferon regulatory factor 3 JBrowse link 1 100,992,244 100,997,202 RGD:1624291
G Nmi N-myc (and STAT) interactor JBrowse link 3 37,458,891 37,480,984 RGD:1624291
negative regulation of interferon-beta production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atg9a autophagy related 9A JBrowse link 9 82,382,800 82,393,429 RGD:1624291
G Cactin cactin, spliceosome C complex subunit JBrowse link 7 11,258,526 11,266,509 RGD:1624291
RGD:1600115
G Nlrc3 NLR family, CARD domain containing 3 JBrowse link 10 11,809,531 11,844,184 RGD:1624291
G Nlrx1 NLR family member X1 JBrowse link 8 48,583,559 48,600,203 RGD:1624291
RGD:1600115
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B JBrowse link 6 8,219,385 8,280,127 RGD:1624291
RGD:1600115
G Ptprs protein tyrosine phosphatase, receptor type, S JBrowse link 9 10,585,360 10,646,205 RGD:1600115
RGD:1624291
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
RGD:1600115
G Rel REL proto-oncogene, NF-kB subunit JBrowse link 14 108,490,794 108,517,582 RGD:1624291
RGD:1600115
G Relb RELB proto-oncogene, NF-kB subunit JBrowse link 1 80,517,081 80,545,019 RGD:1624291
RGD:1600115
G Sirpa signal-regulatory protein alpha JBrowse link 3 122,113,735 122,152,478 RGD:1624291
G Traf3ip1 TRAF3 interacting protein 1 JBrowse link 9 98,621,499 98,658,223 RGD:1624291
G Traip TRAF-interacting protein JBrowse link 8 116,730,170 116,750,528 RGD:1624291
RGD:1600115
G Yy1 YY1 transcription factor JBrowse link 6 132,702,443 132,726,848 RGD:1624291
RGD:1600115
negative regulation of type I interferon production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acod1 aconitate decarboxylase 1 JBrowse link 15 93,612,968 93,622,322 RGD:1624291
G Dhx58 DEXH-box helicase 58 JBrowse link 10 88,599,722 88,611,562 RGD:1624291
RGD:1600115
G Gpatch3 G patch domain containing 3 JBrowse link 5 151,796,456 151,806,007 RGD:1624291
RGD:1600115
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Nmi N-myc (and STAT) interactor JBrowse link 3 37,458,891 37,480,984 RGD:1624291
G Nploc4 NPL4 homolog, ubiquitin recognition factor JBrowse link 10 109,553,518 109,610,087 RGD:1600115
RGD:1624291
G Peli3 pellino E3 ubiquitin protein ligase family member 3 JBrowse link 1 220,191,209 220,204,032 RGD:1624291
G Rnf125 ring finger protein 125 JBrowse link 18 15,193,226 15,225,454 RGD:1624291
RGD:1600115
G Traf3ip1 TRAF3 interacting protein 1 JBrowse link 9 98,621,499 98,658,223 RGD:1624291
RGD:1600115
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 JBrowse link 11 86,304,836 86,328,478 RGD:1624291
RGD:1600115
positive regulation of interferon-alpha biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1624291
RGD:1600115
G Tlr7 toll-like receptor 7 JBrowse link X 28,486,836 28,513,004 RGD:1624291
RGD:1600115
G Tlr8 toll-like receptor 8 JBrowse link X 28,539,158 28,562,803 RGD:1624291
RGD:1600115
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
positive regulation of interferon-alpha production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddx58 DEXD/H-box helicase 58 JBrowse link 5 56,486,584 56,536,898 RGD:1624291
G Flt3 fms-related tyrosine kinase 3 JBrowse link 12 9,360,439 9,437,004 RGD:1624291
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1624291
RGD:1600115
G Ifih1 interferon induced with helicase C domain 1 JBrowse link 3 48,557,696 48,604,097 RGD:1624291
G Irf3 interferon regulatory factor 3 JBrowse link 1 100,992,244 100,997,202 RGD:1624291
RGD:1600115
G Irf7 interferon regulatory factor 7 JBrowse link 1 214,249,388 214,252,909 RGD:1624291
RGD:1600115
G Mavs mitochondrial antiviral signaling protein JBrowse link 3 123,776,147 123,790,572 RGD:1600115
RGD:1624291
G Setd2 SET domain containing 2, histone lysine methyltransferase JBrowse link 8 118,802,478 118,888,224 RGD:1624291
RGD:1600115
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:1624291
G Tbk1 TANK-binding kinase 1 JBrowse link 7 63,655,247 63,687,978 RGD:1624291
RGD:1600115
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:1600115
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 JBrowse link 4 66,012,111 66,062,160 RGD:1624291
positive regulation of interferon-alpha secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:1624291
RGD:1600115
G Ddx58 DEXD/H-box helicase 58 JBrowse link 5 56,486,584 56,536,898 RGD:1624291
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1624291
RGD:1600115
G Dhx9 DExH-box helicase 9 JBrowse link 13 70,885,503 70,922,278 RGD:1624291
RGD:1600115
G Flt3 fms-related tyrosine kinase 3 JBrowse link 12 9,360,439 9,437,004 RGD:1624291
G Hmg1l1 high-mobility group (nonhistone chromosomal) protein 1-like 1 JBrowse link 19 59,984,234 59,985,494 RGD:13792537
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:13792537
G Hmgb4 high-mobility group box 4 JBrowse link 5 146,445,545 146,446,227 RGD:13792537
G Ifih1 interferon induced with helicase C domain 1 JBrowse link 3 48,557,696 48,604,097 RGD:1624291
RGD:1600115
G LOC108349258 high mobility group protein B4-like JBrowse link X 142,344,626 142,345,439 RGD:13792537
G LOC108350839 high mobility group protein B1-like JBrowse link 4 92,431,517 92,432,354 RGD:13792537
G LOC681067 similar to RIKEN cDNA 1700001F22 JBrowse link X 132,424,185 132,424,955 RGD:13792537
G LOC691030 similar to RIKEN cDNA 1700001F22 JBrowse link X 130,794,079 130,794,824 RGD:13792537
G Mavs mitochondrial antiviral signaling protein JBrowse link 3 123,776,147 123,790,572 RGD:1624291
RGD:1600115
G Mmp12 matrix metallopeptidase 12 JBrowse link 8 5,594,717 5,616,494 RGD:1600115
RGD:1624291
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:1624291
RGD:1600115
G RGD1560585 similar to RIKEN cDNA 1700001F22 JBrowse link X 144,001,166 144,001,891 RGD:13792537
G RGD1561558 similar to RIKEN cDNA 1700001F22 JBrowse link X 158,261,123 158,261,953 RGD:13792537
G RGD1566225 similar to RIKEN cDNA 1700001F22 JBrowse link X 137,197,195 137,197,990 RGD:13792537
positive regulation of interferon-beta biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tbk1 TANK-binding kinase 1 JBrowse link 7 63,655,247 63,687,978 RGD:1624291
RGD:1600115
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:1624291
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1624291
RGD:1600115
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:1600115
G Tlr7 toll-like receptor 7 JBrowse link X 28,486,836 28,513,004 RGD:1624291
RGD:13792537
G Tlr8 toll-like receptor 8 JBrowse link X 28,539,158 28,562,803 RGD:1624291
RGD:13792537
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
RGD:13792537
positive regulation of interferon-beta production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddx58 DEXD/H-box helicase 58 JBrowse link 5 56,486,584 56,536,898 RGD:1624291
G Flot1 flotillin 1 JBrowse link 20 3,427,890 3,438,418 RGD:1624291
RGD:1600115
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Hmgb2 high mobility group box 2 JBrowse link 16 36,077,615 36,080,191 RGD:1624291
G Ifih1 interferon induced with helicase C domain 1 JBrowse link 3 48,557,696 48,604,097 RGD:1624291
G Ifnar1 interferon alpha and beta receptor subunit 1 JBrowse link 11 31,640,407 31,666,839 RGD:1624291
G Irf1 interferon regulatory factor 1 JBrowse link 10 39,109,530 39,116,532 RGD:1600115
RGD:1624291
G Irf3 interferon regulatory factor 3 JBrowse link 1 100,992,244 100,997,202 RGD:1624291
RGD:1600115
G Irf7 interferon regulatory factor 7 JBrowse link 1 214,249,388 214,252,909 RGD:1624291
RGD:1600115
G Mavs mitochondrial antiviral signaling protein JBrowse link 3 123,776,147 123,790,572 RGD:1600115
RGD:1624291
G Polr3a RNA polymerase III subunit A JBrowse link 16 717,821 756,002 RGD:1624291
RGD:1600115
G Polr3b RNA polymerase III subunit B JBrowse link 7 24,745,051 24,851,227 RGD:1624291
RGD:1600115
G Polr3c RNA polymerase III subunit C JBrowse link 2 198,836,282 198,852,368 RGD:1624291
RGD:1600115
G Polr3d RNA polymerase III subunit D JBrowse link 15 52,129,471 52,134,140 RGD:1624291
RGD:1600115
G Polr3f RNA polymerase III subunit F JBrowse link 3 138,684,685 138,701,055 RGD:1624291
RGD:1600115
G Polr3g RNA polymerase III subunit G JBrowse link 2 9,537,642 9,578,551 RGD:1624291
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:1600115
RGD:1624291
G Riok3 RIO kinase 3 JBrowse link 18 3,565,166 3,590,739 RGD:1624291
RGD:1600115
G Rnf135 ring finger protein 135 JBrowse link 10 67,531,989 67,551,237 RGD:1624291
RGD:1600115
G Tbk1 TANK-binding kinase 1 JBrowse link 7 63,655,247 63,687,978 RGD:1624291
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1624291
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
G Zbtb20 zinc finger and BTB domain containing 20 JBrowse link 11 62,014,925 62,561,113 RGD:1624291
RGD:1600115
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 JBrowse link 4 66,012,111 66,062,160 RGD:1624291
G Zfp64 zinc finger protein 64 JBrowse link 3 165,713,070 165,741,932 RGD:1624291
positive regulation of interferon-beta secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddx58 DEXD/H-box helicase 58 JBrowse link 5 56,486,584 56,536,898 RGD:1624291
G Dhx9 DExH-box helicase 9 JBrowse link 13 70,885,503 70,922,278 RGD:1624291
RGD:1600115
G Ifih1 interferon induced with helicase C domain 1 JBrowse link 3 48,557,696 48,604,097 RGD:1624291
RGD:1600115
G Mavs mitochondrial antiviral signaling protein JBrowse link 3 123,776,147 123,790,572 RGD:1624291
RGD:1600115
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:1624291
RGD:1600115
positive regulation of type I interferon production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:1624291
RGD:13792537
G Cgas cyclic GMP-AMP synthase JBrowse link 8 85,789,515 85,804,008 RGD:1624291
G Dhx33 DEAH-box helicase 33 JBrowse link 10 57,622,022 57,638,485 RGD:1600115
RGD:1624291
G Dhx58 DEXH-box helicase 58 JBrowse link 10 88,599,722 88,611,562 RGD:1624291
RGD:1600115
G Irak1 interleukin-1 receptor-associated kinase 1 JBrowse link X 156,716,469 156,726,367 RGD:1624291
RGD:1600115
G Irf1 interferon regulatory factor 1 JBrowse link 10 39,109,530 39,116,532 RGD:1624291
RGD:1600115
G Irf7 interferon regulatory factor 7 JBrowse link 1 214,249,388 214,252,909 RGD:1624291
G Mavs mitochondrial antiviral signaling protein JBrowse link 3 123,776,147 123,790,572 RGD:1624291
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:1624291
G Plcg2 phospholipase C, gamma 2 JBrowse link 19 50,039,410 50,173,543 RGD:1624291
RGD:1600115
G Pqbp1 polyglutamine binding protein 1 JBrowse link X 15,448,570 15,453,130 RGD:1624291
RGD:1600115
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:1624291
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1624291
RGD:1600115
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:1624291
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1624291
G Tmem173 transmembrane protein 173 JBrowse link 18 28,529,537 28,535,828 RGD:11344949
RGD:13792537
RGD:1624291
G Trim15 tripartite motif containing 15 JBrowse link 20 2,194,293 2,203,636 RGD:1624291
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 JBrowse link 4 66,012,111 66,062,160 RGD:1624291
G Zcchc3 zinc finger CCHC-type containing 3 JBrowse link 3 147,877,321 147,881,434 RGD:1600115
RGD:1624291
regulation of interferon-beta production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf216 ring finger protein 216 JBrowse link 12 13,508,429 13,631,689 RGD:1624291
RGD:1600115
G Tirap TIR domain containing adaptor protein JBrowse link 8 36,382,029 36,399,625 RGD:1624291
G Traf3 Tnf receptor-associated factor 3 JBrowse link 6 135,610,698 135,720,247 RGD:1624291
RGD:1600115
G Trim38 tripartite motif containing 38 JBrowse link 17 43,600,006 43,607,879 RGD:1624291
regulation of type I interferon production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cgas cyclic GMP-AMP synthase JBrowse link 8 85,789,515 85,804,008 RGD:1624291
G Rnf26 ring finger protein 26 JBrowse link 8 48,447,113 48,449,311 RGD:1624291
RGD:1600115
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
RGD:1600115
type I interferon biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifnar1 interferon alpha and beta receptor subunit 1 JBrowse link 11 31,640,407 31,666,839 RGD:1624291
G Irf3 interferon regulatory factor 3 JBrowse link 1 100,992,244 100,997,202 RGD:1624291
RGD:1600115
G Irf7 interferon regulatory factor 7 JBrowse link 1 214,249,388 214,252,909 RGD:1624291
RGD:1600115
G Irf9 interferon regulatory factor 9 JBrowse link 15 34,282,936 34,288,981 RGD:1624291
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17895
    multicellular organismal process 8519
      cytokine production 767
        type I interferon production 92
          interferon-alpha production + 38
          interferon-beta production + 52
          interferon-delta production + 0
          interferon-epsilon production + 0
          interferon-kappa production + 0
          interferon-omega production + 0
          interferon-tau production + 1
          negative regulation of type I interferon production + 25
          positive regulation of type I interferon production + 60
          regulation of type I interferon production + 89
          type I interferon biosynthetic process + 14
          type I interferon secretion + 19
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.