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ONTOLOGY REPORT - ANNOTATIONS


Term:type I interferon production
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Accession:GO:0032606 term browser browse the term
Definition:The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
Comment:Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
Synonyms:exact_synonym: type I IFN production
 narrow_synonym: type I interferon biosynthetic process;   type I interferon secretion
 alt_id: GO:0045351;   GO:0072641


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negative regulation of interferon-alpha production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR2 hepatitis A virus cellular receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393
JBrowse link
G NLRC3 NLR family CARD domain containing 3 ISO (MGI:5568884|PMID:24560620) UniProt PMID:24560620 MGI:5568884 NCBI chr 6:37,668,654...37,707,387
Ensembl chr 6:37,647,976...37,703,190
JBrowse link
G NMI N-myc and STAT interactor IEA Ensembl GO_REF:0000107 NCBI chr19:52,541,796...52,555,043
Ensembl chr19:52,541,981...52,553,574
JBrowse link
G PTPRS protein tyrosine phosphatase receptor type S IEA Ensembl GO_REF:0000107 NCBI chr20:54,575,853...54,672,141
Ensembl chr20:54,575,895...54,672,068
JBrowse link
negative regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG9A autophagy related 9A ISO (MGI:5569198|PMID:24670807) MGI PMID:24670807 MGI:5569198 NCBI chr37:25,768,287...25,777,529
Ensembl chr37:25,768,275...25,890,811
JBrowse link
G CACTIN cactin, spliceosome C complex subunit IEA Ensembl GO_REF:0000107 NCBI chr20:55,803,494...55,817,467
Ensembl chr20:55,803,530...55,816,549
JBrowse link
G CREBBP CREB binding protein ISO (MGI:2151262|PMID:11583620) CAFA PMID:11583620 MGI:2151262 NCBI chr 6:37,410,201...37,536,688
Ensembl chr 6:37,409,930...37,534,176
JBrowse link
G IRF3 interferon regulatory factor 3 ISO (MGI:3828224|PMID:18851954) MGI PMID:18851954 MGI:3828224 NCBI chr 1:106,875,016...106,879,065
Ensembl chr 1:106,875,118...106,879,065
JBrowse link
G NLRC3 NLR family CARD domain containing 3 ISO (MGI:5568884|PMID:24560620) UniProt PMID:24560620 MGI:5568884 NCBI chr 6:37,668,654...37,707,387
Ensembl chr 6:37,647,976...37,703,190
JBrowse link
G NLRX1 NLR family member X1 IEA Ensembl GO_REF:0000107 NCBI chr 5:14,692,621...14,705,214
Ensembl chr 5:14,564,935...14,705,257
JBrowse link
G NMI N-myc and STAT interactor IEA Ensembl GO_REF:0000107 NCBI chr19:52,541,796...52,555,043
Ensembl chr19:52,541,981...52,553,574
JBrowse link
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B ISO (PMID:22750291) UniProtKB PMID:22750291 NCBI chr10:46,590,110...46,680,792
Ensembl chr10:46,590,079...46,665,866
JBrowse link
G PTPRS protein tyrosine phosphatase receptor type S IEA Ensembl GO_REF:0000107 NCBI chr20:54,575,853...54,672,141
Ensembl chr20:54,575,895...54,672,068
JBrowse link
G PYCARD PYD and CARD domain containing IEA Ensembl GO_REF:0000107 NCBI chr 6:17,049,352...17,051,348
Ensembl chr 6:17,049,705...17,051,240
JBrowse link
G REL REL proto-oncogene, NF-kB subunit IEA Ensembl GO_REF:0000107 NCBI chr10:60,990,264...61,030,162
Ensembl chr10:60,990,197...61,023,663
JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit IEA Ensembl GO_REF:0000107 NCBI chr 1:110,436,677...110,466,709
Ensembl chr 1:110,436,662...110,466,809
JBrowse link
G SIRPA signal regulatory protein alpha ISO (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chr24:19,094,930...19,136,655 JBrowse link
G TRAF3IP1 TRAF3 interacting protein 1 IEA Ensembl GO_REF:0000107 NCBI chr25:48,782,448...48,836,993
Ensembl chr25:48,782,463...48,834,374
JBrowse link
G TRAIP TRAF interacting protein IEA Ensembl GO_REF:0000107 NCBI chr20:39,430,109...39,454,437
Ensembl chr20:39,430,489...39,453,933
JBrowse link
G YY1 YY1 transcription factor IEA Ensembl GO_REF:0000107 NCBI chr 8:68,539,511...68,572,796
Ensembl chr 8:68,539,353...68,568,058
JBrowse link
negative regulation of type I interferon production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 ISO (MGI:5490396|PMID:23609450) UniProt PMID:23609450 MGI:5490396 NCBI chr22:30,545,991...30,557,199
Ensembl chr22:30,547,271...30,555,510
JBrowse link
G DHX58 DExH-box helicase 58 IEA Ensembl GO_REF:0000107 NCBI chr 9:20,787,470...20,795,593
Ensembl chr 9:20,787,541...20,795,361
JBrowse link
G GPATCH3 G-patch domain containing 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:73,243,178...73,250,926
Ensembl chr 2:73,243,222...73,250,403
JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 ISO (MGI:5437532|PMID:22842346) UniProt PMID:22842346 MGI:5437532 NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393
JBrowse link
G ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains IEA Ensembl GO_REF:0000107 NCBI chr12:3,861,063...3,955,356
Ensembl chr12:3,862,477...3,955,348
JBrowse link
G NMI N-myc and STAT interactor ISO (MGI:5546557|PMID:23956435) MGI PMID:23956435 MGI:5546557 NCBI chr19:52,541,796...52,555,043
Ensembl chr19:52,541,981...52,553,574
JBrowse link
G NPLOC4 NPL4 homolog, ubiquitin recognition factor IEA Ensembl GO_REF:0000107 NCBI chr 9:538,087...604,898
Ensembl chr 9:537,840...603,480
JBrowse link
G PELI3 pellino E3 ubiquitin protein ligase family member 3 ISO (MGI:5441107|PMID:23042151) MGI PMID:23042151 MGI:5441107 NCBI chr18:50,870,483...50,881,089
Ensembl chr18:50,872,426...50,879,826
JBrowse link
G RNF125 ring finger protein 125 IEA Ensembl GO_REF:0000107 NCBI chr 7:57,570,779...57,607,485
Ensembl chr 7:57,574,738...57,608,017
JBrowse link
G TRAF3IP1 TRAF3 interacting protein 1 ISO (PMID:22079989) CACAO PMID:22079989 NCBI chr25:48,782,448...48,836,993
Ensembl chr25:48,782,463...48,834,374
JBrowse link
G UFD1 ubiquitin recognition factor in ER associated degradation 1 IEA Ensembl GO_REF:0000107 NCBI chr26:29,739,062...29,763,315
Ensembl chr26:29,739,153...29,763,313
JBrowse link
positive regulation of interferon-alpha production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHUK component of inhibitor of nuclear factor kappa B kinase complex IEA Ensembl GO_REF:0000107 NCBI chr28:12,964,670...13,001,557
Ensembl chr28:12,965,479...13,001,512
JBrowse link
G DDX3X DEAD-box helicase 3 X-linked IEA Ensembl GO_REF:0000107 NCBI chr  X:35,759,367...35,789,759
Ensembl chr  X:35,759,416...35,789,774
JBrowse link
G DDX58 DExD/H-box helicase 58 IEA Ensembl GO_REF:0000107 NCBI chr11:49,764,252...49,799,626
Ensembl chr11:49,764,267...49,799,527
JBrowse link
G DHX36 DEAH-box helicase 36 IEA Ensembl GO_REF:0000107 NCBI chr23:48,404,351...48,456,360
Ensembl chr23:48,407,316...48,456,654
JBrowse link
G DHX9 DExH-box helicase 9 IEA Ensembl GO_REF:0000107 NCBI chr 7:16,233,763...16,292,576
Ensembl chr 7:16,233,814...16,292,618
JBrowse link
G FAM149A family with sequence similarity 149 member A IEA Ensembl GO_REF:0000107 NCBI chr16:44,550,726...44,603,466
Ensembl chr16:44,550,846...44,653,247
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 ISO (MGI:4452060|PMID:20457904) MGI PMID:20457904 MGI:4452060 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284
JBrowse link
G HMGB1 high mobility group box 1 ISO (MGI:4367121|PMID:19890330) UniProt PMID:19890330 MGI:4367121 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 IEA Ensembl GO_REF:0000107 NCBI chr37:7,010,421...7,025,912 JBrowse link
G IFIH1 interferon induced with helicase C domain 1 ISO (PMID:19656871), (PMID:21957149) UniProt PMID:19656871, PMID:21957149 NCBI chr36:7,668,925...7,727,040
Ensembl chr36:7,649,727...8,261,048
JBrowse link
G IRF3 interferon regulatory factor 3 ISO (MGI:4365354|PMID:18562536) UniProt PMID:18562536 MGI:4365354 NCBI chr 1:106,875,016...106,879,065
Ensembl chr 1:106,875,118...106,879,065
JBrowse link
G MAVS mitochondrial antiviral signaling protein IEA Ensembl GO_REF:0000107 NCBI chr24:17,510,209...17,529,286
Ensembl chr24:17,512,761...17,523,807
JBrowse link
G MMP12 matrix metallopeptidase 12 IEA Ensembl GO_REF:0000107 NCBI chr 5:28,918,626...28,933,404
Ensembl chr 5:28,918,594...28,933,309
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IEA Ensembl GO_REF:0000107 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858
JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase IEA Ensembl GO_REF:0000107 NCBI chr20:41,675,539...41,800,697
Ensembl chr20:41,675,599...41,800,612
JBrowse link
G STAT1 signal transducer and activator of transcription 1 IEA Ensembl GO_REF:0000107 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178
JBrowse link
G TBK1 TANK binding kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr10:7,169,664...7,208,890
Ensembl chr10:7,168,007...7,208,899
JBrowse link
G TLR3 toll like receptor 3 IEA Ensembl GO_REF:0000107 NCBI chr16:44,617,012...44,633,591
Ensembl chr16:44,550,846...44,653,247
JBrowse link
G TLR4 toll like receptor 4 IEA Ensembl GO_REF:0000107 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165
JBrowse link
G TLR7 toll like receptor 7 IEA Ensembl GO_REF:0000107 NCBI chr  X:9,331,243...9,360,461
Ensembl chr  X:9,314,815...9,359,603
JBrowse link
G TLR8 toll like receptor 8 ISO (PMID:16286015) UniProt PMID:16286015 NCBI chr  X:9,381,159...9,399,938 JBrowse link
G TLR9 toll like receptor 9 ISS UniProt GO_REF:0000024 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 ISO (PMID:21102435) UniProtKB PMID:21102435 NCBI chr16:9,598,339...9,660,540
Ensembl chr16:9,598,405...9,664,569
JBrowse link
positive regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked IEA Ensembl GO_REF:0000107 NCBI chr  X:35,759,367...35,789,759
Ensembl chr  X:35,759,416...35,789,774
JBrowse link
G DDX58 DExD/H-box helicase 58 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:49,764,252...49,799,626
Ensembl chr11:49,764,267...49,799,527
JBrowse link
G DHX58 DExH-box helicase 58 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:20,787,470...20,795,593
Ensembl chr 9:20,787,541...20,795,361
JBrowse link
G DHX9 DExH-box helicase 9 IEA Ensembl GO_REF:0000107 NCBI chr 7:16,233,763...16,292,576
Ensembl chr 7:16,233,814...16,292,618
JBrowse link
G FAM149A family with sequence similarity 149 member A IEA Ensembl GO_REF:0000107 NCBI chr16:44,550,726...44,603,466
Ensembl chr16:44,550,846...44,653,247
JBrowse link
G FLOT1 flotillin 1 IEA Ensembl GO_REF:0000107 NCBI chr12:517,941...528,677
Ensembl chr12:516,032...528,637
JBrowse link
G HMGB1 high mobility group box 1 IEA Ensembl GO_REF:0000107 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165
JBrowse link
G HMGB2 high mobility group box 2 IEA Ensembl GO_REF:0000107 NCBI chr25:23,939,024...23,941,720
Ensembl chr25:23,939,027...23,941,606
JBrowse link
G IFIH1 interferon induced with helicase C domain 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr36:7,668,925...7,727,040
Ensembl chr36:7,649,727...8,261,048
JBrowse link
G IRF1 interferon regulatory factor 1 IEA Ensembl GO_REF:0000107 NCBI chr11:20,773,801...20,781,106
Ensembl chr11:20,760,120...20,781,608
JBrowse link
G IRF3 interferon regulatory factor 3 ISO (MGI:4365354|PMID:18562536) UniProt PMID:18562536 MGI:4365354 NCBI chr 1:106,875,016...106,879,065
Ensembl chr 1:106,875,118...106,879,065
JBrowse link
G LOC609830 interferon alpha/beta receptor 1 ISO (MGI:5619426|PMID:24598055) CACAO PMID:24598055 MGI:5619426 NCBI chr31:28,854,765...28,876,399 JBrowse link
G MAVS mitochondrial antiviral signaling protein IEA Ensembl GO_REF:0000107 NCBI chr24:17,510,209...17,529,286
Ensembl chr24:17,512,761...17,523,807
JBrowse link
G POLR3A RNA polymerase III subunit A IEA Ensembl GO_REF:0000107 NCBI chr 4:27,834,197...27,883,065
Ensembl chr 4:27,835,612...27,883,436
JBrowse link
G POLR3B RNA polymerase III subunit B IEA Ensembl GO_REF:0000107 NCBI chr10:32,202,188...32,309,775
Ensembl chr10:32,202,190...32,309,614
JBrowse link
G POLR3C RNA polymerase III subunit C IEA Ensembl GO_REF:0000107 NCBI chr17:58,634,299...58,646,056
Ensembl chr17:58,636,244...58,645,838
JBrowse link
G POLR3D RNA polymerase III subunit D IEA Ensembl GO_REF:0000107 NCBI chr25:35,011,189...35,016,617
Ensembl chr25:35,011,861...35,016,605
JBrowse link
G POLR3F RNA polymerase III subunit F IEA Ensembl GO_REF:0000107 NCBI chr24:4,715,146...4,727,938
Ensembl chr24:4,663,302...4,727,920
JBrowse link
G POLR3G RNA polymerase III subunit G ISO (PMID:19609254), (PMID:19631370) UniProtKB PMID:19609254, PMID:19631370 NCBI chr 3:18,426,169...18,529,304
Ensembl chr 3:18,427,985...18,467,801
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 IEA Ensembl GO_REF:0000107 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IEA Ensembl GO_REF:0000107 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858
JBrowse link
G RIOK3 RIO kinase 3 IEA Ensembl GO_REF:0000107 NCBI chr 7:64,835,810...64,860,464
Ensembl chr 7:64,837,233...64,860,393
JBrowse link
G RNF135 ring finger protein 135 IEA Ensembl GO_REF:0000107 NCBI chr 9:40,794,772...40,809,022
Ensembl chr 9:40,795,297...40,808,737
JBrowse link
G TBK1 TANK binding kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr10:7,169,664...7,208,890
Ensembl chr10:7,168,007...7,208,899
JBrowse link
G TICAM1 toll like receptor adaptor molecule 1 ISO (MGI:2670551|PMID:12872135)
(MGI:2669022|PMID:12855817)
MGI PMID:12855817, PMID:12872135 MGI:2669022, MGI:2670551 NCBI chr20:54,948,237...54,961,996
Ensembl chr20:54,959,525...54,961,780
JBrowse link
G TLR2 toll like receptor 2 ISO (MGI:4456948|PMID:15356140) BHF-UCL PMID:15356140 MGI:4456948 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241
JBrowse link
G TLR3 toll like receptor 3 IEA Ensembl GO_REF:0000107 NCBI chr16:44,617,012...44,633,591
Ensembl chr16:44,550,846...44,653,247
JBrowse link
G TLR4 toll like receptor 4 IEA Ensembl GO_REF:0000107 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165
JBrowse link
G TLR7 toll like receptor 7 IEA Ensembl GO_REF:0000107 NCBI chr  X:9,331,243...9,360,461
Ensembl chr  X:9,314,815...9,359,603
JBrowse link
G TLR8 toll like receptor 8 ISO (PMID:16286015) UniProt PMID:16286015 NCBI chr  X:9,381,159...9,399,938 JBrowse link
G TLR9 toll like receptor 9 ISS UniProt GO_REF:0000024 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
JBrowse link
G ZBTB20 zinc finger and BTB domain containing 20 IEA Ensembl GO_REF:0000107 NCBI chr33:18,860,824...19,277,691
Ensembl chr33:18,529,132...18,759,058
JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 ISO (PMID:21102435) UniProtKB PMID:21102435 NCBI chr16:9,598,339...9,660,540
Ensembl chr16:9,598,405...9,664,569
JBrowse link
G ZFP64 ZFP64 zinc finger protein ISO (MGI:5619431|PMID:23857586) CACAO PMID:23857586 MGI:5619431 NCBI chr24:38,201,824...38,289,395
Ensembl chr24:38,203,028...38,289,580
JBrowse link
positive regulation of type I interferon production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule ISO (MGI:5300392|PMID:22078883) CACAO PMID:22078883 MGI:5300392 NCBI chr 2:35,790,505...35,792,967 JBrowse link
G CGAS cyclic GMP-AMP synthase IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr12:35,511,920...35,528,759
Ensembl chr12:35,512,860...35,528,596
JBrowse link
G DHX33 DEAH-box helicase 33 ISO (MGI:6120210|PMID:24037184) UniProt PMID:24037184 MGI:6120210 NCBI chr 5:31,337,447...31,351,447
Ensembl chr 5:31,338,620...31,346,422
JBrowse link
G DHX58 DExH-box helicase 58 ISO (MGI:4421606|PMID:20080593) UniProt PMID:20080593 MGI:4421606 NCBI chr 9:20,787,470...20,795,593
Ensembl chr 9:20,787,541...20,795,361
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr  X:121,853,340...121,862,582
Ensembl chr  X:121,819,432...121,862,576
JBrowse link
G IRF1 interferon regulatory factor 1 ISO (MGI:3691368|PMID:17018642) UniProt PMID:17018642 MGI:3691368 NCBI chr11:20,773,801...20,781,106
Ensembl chr11:20,760,120...20,781,608
JBrowse link
G IRF3 interferon regulatory factor 3 ISO (PMID:25636800) UniProt PMID:25636800 NCBI chr 1:106,875,016...106,879,065
Ensembl chr 1:106,875,118...106,879,065
JBrowse link
G IRF5 interferon regulatory factor 5 IEA Ensembl GO_REF:0000107 NCBI chr14:7,724,168...7,734,976
Ensembl chr14:7,724,780...7,742,795
JBrowse link
G MAVS mitochondrial antiviral signaling protein ISO (MGI:3807296|PMID:18780793) MGI PMID:18780793 MGI:3807296 NCBI chr24:17,510,209...17,529,286
Ensembl chr24:17,512,761...17,523,807
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor IEA Ensembl GO_REF:0000107 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534
JBrowse link
G PLCG2 phospholipase C gamma 2 IEA Ensembl GO_REF:0000107 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049
JBrowse link
G PQBP1 polyglutamine binding protein 1 IEA Ensembl GO_REF:0000107 NCBI chr  X:42,056,660...42,060,508
Ensembl chr  X:42,056,708...42,121,818
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 ISO (PMID:23871208) UniProtKB PMID:23871208 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858
JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 2:34,783,947...34,792,204
Ensembl chr 2:34,784,232...34,789,072
JBrowse link
G SYK spleen associated tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583
JBrowse link
G TICAM1 toll like receptor adaptor molecule 1 ISO (MGI:2670551|PMID:12872135) MGI PMID:12872135 MGI:2670551 NCBI chr20:54,948,237...54,961,996
Ensembl chr20:54,959,525...54,961,780
JBrowse link
G TLR3 toll like receptor 3 ISO (MGI:3774796|PMID:18207576) MGI PMID:18207576 MGI:3774796 NCBI chr16:44,617,012...44,633,591
Ensembl chr16:44,550,846...44,653,247
JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 ISO (MGI:4868308|PMID:21102435) MGI PMID:21102435 MGI:4868308 NCBI chr16:9,598,339...9,660,540
Ensembl chr16:9,598,405...9,664,569
JBrowse link
G ZCCHC3 zinc finger CCHC-type containing 3 ISO (MGI:6209107|PMID:30135424) UniProt PMID:30135424 MGI:6209107 NCBI chr24:20,537,849...20,540,098 JBrowse link
regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF216 ring finger protein 216 IEA Ensembl GO_REF:0000107 NCBI chr 6:12,185,870...12,347,461
Ensembl chr 6:12,185,846...12,361,869
JBrowse link
G TIRAP TIR domain containing adaptor protein ISO (MGI:4942245|PMID:14630816) BHF-UCL PMID:14630816 MGI:4942245 NCBI chr 5:8,222,217...8,237,595
Ensembl chr 5:8,221,794...8,226,074
JBrowse link
G TRAF3 TNF receptor associated factor 3 IEA Ensembl GO_REF:0000107 NCBI chr 8:70,739,389...70,794,448
Ensembl chr 8:70,739,417...70,790,645
JBrowse link
G TRIM38 tripartite motif containing 38 ISO (MGI:5441682|PMID:22539786) MGI PMID:22539786 MGI:5441682 NCBI chr35:23,894,521...23,939,392
Ensembl chr35:23,926,287...23,939,466
JBrowse link
regulation of type I interferon production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CGAS cyclic GMP-AMP synthase ISO (MGI:5699498|PMID:26371324) MGI PMID:26371324 MGI:5699498 NCBI chr12:35,511,920...35,528,759
Ensembl chr12:35,512,860...35,528,596
JBrowse link
G IRF8 interferon regulatory factor 8 IEA Ensembl GO_REF:0000107 NCBI chr 5:66,789,264...66,812,477
Ensembl chr 5:66,791,350...66,842,179
JBrowse link
G POLA1 DNA polymerase alpha 1, catalytic subunit ISO (PMID:27019227) UniProt PMID:27019227 NCBI chr  X:20,227,808...20,537,893
Ensembl chr  X:20,227,886...20,537,902
JBrowse link
G RNF26 ring finger protein 26 ISO (PMID:25254379) UniProtKB PMID:25254379 NCBI chr 5:14,564,949...14,567,756 JBrowse link
G TBK1 TANK binding kinase 1 ISO (PMID:25636800) UniProt PMID:25636800 NCBI chr10:7,169,664...7,208,890
Ensembl chr10:7,168,007...7,208,899
JBrowse link
G TREX1 three prime repair exonuclease 1 IEA Ensembl GO_REF:0000107 NCBI chr20:40,624,845...40,626,840
Ensembl chr20:40,624,891...40,626,906
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16190
    multicellular organismal process 7608
      cytokine production 718
        type I interferon production 83
          interferon-alpha production + 27
          interferon-beta production + 53
          interferon-delta production 0
          interferon-epsilon production 0
          interferon-kappa production 0
          interferon-omega production 0
          interferon-tau production 0
          negative regulation of type I interferon production + 25
          positive regulation of type I interferon production + 52
          regulation of type I interferon production + 83
Path 2
Term Annotations click to browse term
  biological_process 16190
    metabolic process 10657
      organic substance metabolic process 10132
        macromolecule metabolic process 8794
          gene expression 5418
            cytokine production 718
              type I interferon production 83
                interferon-alpha production + 27
                interferon-beta production + 53
                interferon-delta production 0
                interferon-epsilon production 0
                interferon-kappa production 0
                interferon-omega production 0
                interferon-tau production 0
                negative regulation of type I interferon production + 25
                positive regulation of type I interferon production + 52
                regulation of type I interferon production + 83
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.