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ONTOLOGY REPORT - ANNOTATIONS


Term:type I interferon production
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Accession:GO:0032606 term browser browse the term
Definition:The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
Comment:Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
Synonyms:exact_synonym: type I IFN production
 narrow_synonym: type I interferon biosynthetic process;   type I interferon secretion
 alt_id: GO:0045351;   GO:0072641


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negative regulation of interferon-alpha production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR2 hepatitis A virus cellular receptor 2 IDA (PMID:26492563) UniProtKB PMID:26492563 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,832...157,142,869
JBrowse link
G IL10 interleukin 10 NAS (PMID:9637497) UniProt PMID:9637497 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G LILRA4 leukocyte immunoglobulin like receptor A4 IMP (PMID:16735691) UniProtKB PMID:16735691 NCBI chr19:54,333,185...54,339,162
Ensembl chr19:54,333,185...54,339,162
JBrowse link
G NLRC3 NLR family CARD domain containing 3 ISS UniProtKB GO_REF:0000024 NCBI chr16:3,539,033...3,577,782
Ensembl chr16:3,539,033...3,577,403
JBrowse link
G NMI N-myc and STAT interactor IEA Ensembl GO_REF:0000107 NCBI chr 2:151,270,465...151,289,668
Ensembl chr 2:151,270,470...151,289,894
JBrowse link
G PTPRS protein tyrosine phosphatase receptor type S IMP (PMID:26231120) UniProtKB PMID:26231120 NCBI chr19:5,205,503...5,340,812
Ensembl chr19:5,158,495...5,340,803
JBrowse link
negative regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG9A autophagy related 9A ISO (MGI:5569198|PMID:24670807) MGI PMID:24670807 MGI:5569198 NCBI chr 2:219,219,380...219,229,636
Ensembl chr 2:219,219,380...219,229,717
JBrowse link
G CACTIN cactin, spliceosome C complex subunit IMP (PMID:20829348) UniProtKB PMID:20829348 NCBI chr19:3,610,645...3,626,810
Ensembl chr19:3,610,645...3,626,815
JBrowse link
G CREBBP CREB binding protein ISO (MGI:2151262|PMID:11583620) CAFA PMID:11583620 MGI:2151262 NCBI chr16:3,725,054...3,880,727
Ensembl chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G IRF3 interferon regulatory factor 3 ISO (MGI:3828224|PMID:18851954) MGI PMID:18851954 MGI:3828224 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G LILRB1 leukocyte immunoglobulin like receptor B1 IDA (PMID:21213105) UniProt PMID:21213105 NCBI chr19:54,616,939...54,637,925
Ensembl chr19:54,617,158...54,637,528
JBrowse link
G NLRC3 NLR family CARD domain containing 3 ISS UniProtKB GO_REF:0000024 NCBI chr16:3,539,033...3,577,782
Ensembl chr16:3,539,033...3,577,403
JBrowse link
G NLRX1 NLR family member X1 IEA Ensembl GO_REF:0000107 NCBI chr11:119,168,334...119,184,016
Ensembl chr11:119,166,568...119,184,016
JBrowse link
G NMI N-myc and STAT interactor IEA Ensembl GO_REF:0000107 NCBI chr 2:151,270,465...151,289,668
Ensembl chr 2:151,270,470...151,289,894
JBrowse link
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B IMP (PMID:22750291) UniProtKB PMID:22750291 NCBI chr 2:44,168,853...44,247,330
Ensembl chr 2:44,167,969...44,244,384
JBrowse link
G PTPRS protein tyrosine phosphatase receptor type S IMP (PMID:26231120) UniProtKB PMID:26231120 NCBI chr19:5,205,503...5,340,812
Ensembl chr19:5,158,495...5,340,803
JBrowse link
G PYCARD PYD and CARD domain containing IMP (PMID:19158675) UniProtKB PMID:19158675 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450
JBrowse link
G REL REL proto-oncogene, NF-kB subunit IDA (PMID:22065573) CACAO PMID:22065573 NCBI chr 2:60,881,521...60,931,612
Ensembl chr 2:60,881,521...60,931,610
Ensembl chr 2:60,881,521...60,931,610
JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit IMP (PMID:22065573) CACAO PMID:22065573 NCBI chr19:45,001,449...45,038,194
Ensembl chr19:45,001,449...45,038,198
JBrowse link
G SIRPA signal regulatory protein alpha ISS ARUK-UCL GO_REF:0000024 NCBI chr20:1,894,167...1,940,592
Ensembl chr20:1,894,167...1,940,592
JBrowse link
G TRAF3IP1 TRAF3 interacting protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:238,320,489...238,400,900
Ensembl chr 2:238,320,441...238,400,897
JBrowse link
G TRAIP TRAF interacting protein IEA Ensembl GO_REF:0000107 NCBI chr 3:49,828,595...49,856,584
Ensembl chr 3:49,828,601...49,856,574
JBrowse link
G YY1 YY1 transcription factor IDA (PMID:16260628) UniProtKB PMID:16260628 NCBI chr14:100,239,144...100,282,788
Ensembl chr14:100,238,298...100,282,788
JBrowse link
negative regulation of type I interferon production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 ISS UniProtKB GO_REF:0000024 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638
JBrowse link
G CYLD CYLD lysine 63 deubiquitinase TAS Reactome Reactome:R-HSA-936440 NCBI chr16:50,742,086...50,801,935
Ensembl chr16:50,742,050...50,801,935
JBrowse link
G DDX58 DExD/H-box helicase 58 TAS Reactome Reactome:R-HSA-936440 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,208
JBrowse link
G DHX58 DExH-box helicase 58 IDA (PMID:21525357) UniProtKB PMID:21525357 NCBI chr17:42,101,404...42,112,721
Ensembl chr17:42,101,404...42,112,714
JBrowse link
G GPATCH3 G-patch domain containing 3 IMP
IBA
IEA
(PMID:28414768)
(PMID:21873635)
UniProtKB
GO_Central
InterPro
PMID:21873635, PMID:28414768 GO_REF:0000002 NCBI chr 1:26,890,488...26,900,467
Ensembl chr 1:26,890,488...26,900,467
JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 ISO (MGI:5437532|PMID:22842346) UniProt PMID:22842346 MGI:5437532 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,832...157,142,869
JBrowse link
G HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 TAS Reactome Reactome:R-HSA-936440 NCBI chr 4:88,456,604...88,506,170
Ensembl chr 4:88,457,119...88,506,163
JBrowse link
G IFIH1 interferon induced with helicase C domain 1 TAS Reactome Reactome:R-HSA-936440 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684
JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon TAS Reactome Reactome:R-HSA-936440 NCBI chr 1:206,470,243...206,496,890
Ensembl chr 1:206,470,476...206,496,889
JBrowse link
G ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains IMP (PMID:29802199) UniProt PMID:29802199 NCBI chr 6:34,587,288...34,696,767
Ensembl chr 6:34,587,288...34,696,859
JBrowse link
G IRF3 interferon regulatory factor 3 TAS Reactome Reactome:R-HSA-936440 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G ISG15 ISG15 ubiquitin like modifier TAS Reactome Reactome:R-HSA-936440 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540
JBrowse link
G ITCH itchy E3 ubiquitin protein ligase TAS Reactome Reactome:R-HSA-936440 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,241...34,540,748
JBrowse link
G MAVS mitochondrial antiviral signaling protein TAS Reactome Reactome:R-HSA-936440 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123
JBrowse link
G NLRC5 NLR family CARD domain containing 5 TAS Reactome Reactome:R-HSA-936440 NCBI chr16:56,989,557...57,083,520
Ensembl chr16:56,989,485...57,083,531
JBrowse link
G NLRX1 NLR family member X1 TAS Reactome Reactome:R-HSA-936440 NCBI chr11:119,168,334...119,184,016
Ensembl chr11:119,166,568...119,184,016
JBrowse link
G NMI N-myc and STAT interactor ISO (MGI:5546557|PMID:23956435) MGI PMID:23956435 MGI:5546557 NCBI chr 2:151,270,465...151,289,668
Ensembl chr 2:151,270,470...151,289,894
JBrowse link
G NPLOC4 NPL4 homolog, ubiquitin recognition factor IMP (PMID:26471729) UniProtKB PMID:26471729 NCBI chr17:81,556,885...81,637,148
Ensembl chr17:81,556,887...81,648,465
JBrowse link
G OTUD5 OTU deubiquitinase 5 TAS Reactome Reactome:R-HSA-936440 NCBI chr  X:48,922,024...48,960,783
Ensembl chr  X:48,922,028...48,958,386
JBrowse link
G PCBP2 poly(rC) binding protein 2 TAS Reactome Reactome:R-HSA-936440 NCBI chr12:53,452,102...53,481,162
Ensembl chr12:53,452,102...53,481,162
JBrowse link
G PELI3 pellino E3 ubiquitin protein ligase family member 3 ISO (MGI:5441107|PMID:23042151) MGI PMID:23042151 MGI:5441107 NCBI chr11:66,466,327...66,477,337
Ensembl chr11:66,466,327...66,477,337
JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 TAS Reactome Reactome:R-HSA-936440 NCBI chr19:9,835,318...9,849,689
Ensembl chr19:9,835,257...9,849,682
Ensembl chr19:9,835,257...9,849,682
JBrowse link
G RNF125 ring finger protein 125 IDA (PMID:17460044), (PMID:26471729) UniProtKB PMID:17460044, PMID:26471729 NCBI chr18:32,018,585...32,090,756
Ensembl chr18:32,018,825...32,073,219
JBrowse link
G RNF135 ring finger protein 135 TAS Reactome Reactome:R-HSA-936440 NCBI chr17:30,968,642...30,999,911
Ensembl chr17:30,970,984...30,999,911
JBrowse link
G RNF216 ring finger protein 216 TAS Reactome Reactome:R-HSA-936440 NCBI chr 7:5,620,047...5,781,721
Ensembl chr 7:5,620,047...5,781,696
Ensembl chr 7:5,620,047...5,781,696
JBrowse link
G TAX1BP1 Tax1 binding protein 1 TAS Reactome Reactome:R-HSA-936440 NCBI chr 7:27,739,373...27,829,767
Ensembl chr 7:27,739,331...27,844,564
JBrowse link
G TBK1 TANK binding kinase 1 TAS Reactome Reactome:R-HSA-936440 NCBI chr12:64,452,105...64,502,114
Ensembl chr12:64,452,092...64,502,114
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 TAS Reactome Reactome:R-HSA-936440 NCBI chr 6:137,866,317...137,883,312
Ensembl chr 6:137,867,214...137,883,312
JBrowse link
G TRAF3IP1 TRAF3 interacting protein 1 IMP (PMID:22079989) CACAO PMID:22079989 NCBI chr 2:238,320,489...238,400,900
Ensembl chr 2:238,320,441...238,400,897
JBrowse link
G TRIM25 tripartite motif containing 25 TAS Reactome Reactome:R-HSA-936440 NCBI chr17:56,887,909...56,914,049
Ensembl chr17:56,836,387...56,914,080
JBrowse link
G UBA7 ubiquitin like modifier activating enzyme 7 TAS Reactome Reactome:R-HSA-936440 NCBI chr 3:49,805,205...49,813,953
Ensembl chr 3:49,805,209...49,813,953
JBrowse link
G UBE2L6 ubiquitin conjugating enzyme E2 L6 TAS Reactome Reactome:R-HSA-936440 NCBI chr11:57,551,662...57,567,935
Ensembl chr11:57,551,656...57,568,284
JBrowse link
G UFD1 ubiquitin recognition factor in ER associated degradation 1 IMP (PMID:26471729) UniProtKB PMID:26471729 NCBI chr22:19,449,911...19,479,193
Ensembl chr22:19,449,911...19,479,202
JBrowse link
positive regulation of interferon-alpha production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHUK component of inhibitor of nuclear factor kappa B kinase complex IMP (PMID:24784232) CAFA PMID:24784232 NCBI chr10:100,188,300...100,229,610
Ensembl chr10:100,188,300...100,229,596
JBrowse link
G DDX3X DEAD-box helicase 3 X-linked IDA (PMID:30341167) UniProt PMID:30341167 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472
Ensembl chr  X:41,333,348...41,364,472
JBrowse link
G DDX58 DExD/H-box helicase 58 IDA
IMP
(PMID:19576794)
(PMID:19609254), (PMID:21957149)
UniProtKB
UniProt
PMID:19576794, PMID:19609254, PMID:21957149 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,208
JBrowse link
G DHX36 DEAH-box helicase 36 IMP (PMID:20696886) UniProt PMID:20696886 NCBI chr 3:154,272,546...154,324,487
Ensembl chr 3:154,272,546...154,324,487
JBrowse link
G DHX9 DExH-box helicase 9 IMP (PMID:21957149) UniProt PMID:21957149 NCBI chr 1:182,839,347...182,887,982
Ensembl chr 1:182,839,347...182,887,982
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 ISO (MGI:4452060|PMID:20457904) MGI PMID:20457904 MGI:4452060 NCBI chr13:28,003,274...28,100,587
Ensembl chr13:28,003,274...28,100,592
JBrowse link
G HMGB1 high mobility group box 1 IEA Ensembl GO_REF:0000107 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 IDA
IBA
(PMID:17164250)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:17164250, PMID:21873635 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737
JBrowse link
G IFIH1 interferon induced with helicase C domain 1 TAS
IMP
(PMID:17079289)
(PMID:19656871), (PMID:21957149)
BHF-UCL
UniProt
PMID:17079289, PMID:19656871, PMID:21957149 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684
JBrowse link
G IRF3 interferon regulatory factor 3 ISS UniProtKB GO_REF:0000024 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G IRF5 interferon regulatory factor 5 IC (PMID:22412986) BHF-UCL PMID:22412986 NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038
JBrowse link
G IRF7 interferon regulatory factor 7 IDA
TAS
(PMID:16127453)
(PMID:16979567)
BHF-UCL
UniProtKB
PMID:16127453, PMID:16979567 NCBI chr11:612,555...615,999
Ensembl chr11:612,553...615,983
JBrowse link
G MAVS mitochondrial antiviral signaling protein IDA
IMP
(PMID:16127453)
(PMID:19609254), (PMID:21957149)
BHF-UCL
UniProt
PMID:16127453, PMID:19609254, PMID:21957149 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123
JBrowse link
G MMP12 matrix metallopeptidase 12 IEA Ensembl GO_REF:0000107 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IEA Ensembl GO_REF:0000107 NCBI chr 1:113,813,811...113,871,761
Ensembl chr 1:113,813,811...113,871,753
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 NAS (PMID:22412986) BHF-UCL PMID:22412986 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064
JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase IDA (PMID:28753426) UniProtKB PMID:28753426 NCBI chr 3:47,016,431...47,164,113
Ensembl chr 3:47,016,429...47,164,113
Ensembl chr 3:47,016,429...47,164,113
JBrowse link
G STAT1 signal transducer and activator of transcription 1 IDA (PMID:28753426) UniProtKB PMID:28753426 NCBI chr 2:190,968,989...191,014,197
Ensembl chr 2:190,908,460...191,020,960
Ensembl chr 2:190,908,460...191,020,960
JBrowse link
G TBK1 TANK binding kinase 1 IDA (PMID:16127453) BHF-UCL PMID:16127453 NCBI chr12:64,452,105...64,502,114
Ensembl chr12:64,452,092...64,502,114
JBrowse link
G TLR3 toll like receptor 3 IDA (PMID:16286015) UniProt PMID:16286015 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,069,152...186,088,069
Ensembl chr 4:186,069,152...186,088,069
JBrowse link
G TLR4 toll like receptor 4 ISS BHF-UCL GO_REF:0000024 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TLR7 toll like receptor 7 IDA (PMID:16286015) UniProt PMID:16286015 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361
JBrowse link
G TLR8 toll like receptor 8 IDA (PMID:16286015) UniProt PMID:16286015 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169
JBrowse link
G TLR9 toll like receptor 9 IDA (PMID:16286015) UniProt PMID:16286015 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,226,163
JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 IDA (PMID:21102435) UniProtKB PMID:21102435 NCBI chr 7:139,043,515...139,109,720
Ensembl chr 7:139,043,515...139,109,720
JBrowse link
positive regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked TAS
IDA
(PMID:18583960), (PMID:18636090)
(PMID:27980081), (PMID:31575075)
UniProtKB
UniProt
PMID:18583960, PMID:18636090, PMID:27980081, PMID:31575075 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472
Ensembl chr  X:41,333,348...41,364,472
JBrowse link
G DDX58 DExD/H-box helicase 58 IDA
IBA
IMP
(PMID:17079289)
(PMID:21873635)
(PMID:19211564), (PMID:19609254), (PMID:19631370), (PMID:21957149)
BHF-UCL
GO_Central
UniProt
PMID:17079289, PMID:19211564, PMID:19609254, PMID:19631370, PMID:21873635, PMID:21957149 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,208
JBrowse link
G DHX58 DExH-box helicase 58 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:42,101,404...42,112,721
Ensembl chr17:42,101,404...42,112,714
JBrowse link
G DHX9 DExH-box helicase 9 IMP (PMID:21957149) UniProt PMID:21957149 NCBI chr 1:182,839,347...182,887,982
Ensembl chr 1:182,839,347...182,887,982
JBrowse link
G FLOT1 flotillin 1 IMP (PMID:25204797) UniProtKB PMID:25204797 NCBI chr 6:30,727,709...30,742,847
Ensembl chr 6:30,727,709...30,742,732
JBrowse link
G HMGB1 high mobility group box 1 IEA Ensembl GO_REF:0000107 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G HMGB2 high mobility group box 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:173,331,376...173,334,358
Ensembl chr 4:173,331,376...173,334,432
JBrowse link
G IFIH1 interferon induced with helicase C domain 1 TAS
IBA
IMP
IDA
(PMID:17079289)
(PMID:21873635)
(PMID:19211564), (PMID:19656871), (PMID:21957149)
(PMID:17600090)
BHF-UCL
GO_Central
UniProt
UniProtKB
PMID:17079289, PMID:17600090, PMID:19211564, PMID:19656871, PMID:21873635, PMID:21957149 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684
JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 ISO (MGI:5619426|PMID:24598055) CACAO PMID:24598055 MGI:5619426 NCBI chr21:33,324,395...33,359,864
Ensembl chr21:33,324,429...33,359,864
JBrowse link
G IRF1 interferon regulatory factor 1 IMP (PMID:21389130) UniProtKB PMID:21389130 NCBI chr 5:132,481,609...132,490,789
Ensembl chr 5:132,481,609...132,490,777
JBrowse link
G IRF3 interferon regulatory factor 3 TAS
ISS
(PMID:16979567) UniProtKB PMID:16979567 GO_REF:0000024 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G IRF5 interferon regulatory factor 5 IC (PMID:22412986) BHF-UCL PMID:22412986 NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038
JBrowse link
G IRF7 interferon regulatory factor 7 IMP
TAS
(PMID:22065573)
(PMID:16979567)
CACAO
UniProtKB
PMID:16979567, PMID:22065573 NCBI chr11:612,555...615,999
Ensembl chr11:612,553...615,983
JBrowse link
G MAVS mitochondrial antiviral signaling protein IDA
IMP
(PMID:16127453)
(PMID:19609254), (PMID:19631370), (PMID:21957149)
BHF-UCL
UniProt
PMID:16127453, PMID:19609254, PMID:19631370, PMID:21957149 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123
JBrowse link
G POLR3A RNA polymerase III subunit A IMP (PMID:19609254) UniProtKB PMID:19609254 NCBI chr10:77,975,149...78,029,515
Ensembl chr10:77,969,251...78,029,515
JBrowse link
G POLR3B RNA polymerase III subunit B IMP (PMID:19609254) UniProtKB PMID:19609254 NCBI chr12:106,357,712...106,510,198
Ensembl chr12:106,357,748...106,510,198
JBrowse link
G POLR3C RNA polymerase III subunit C IMP (PMID:19609254) UniProtKB PMID:19609254 NCBI chr 1:145,823,183...145,844,402
Ensembl chr 1:145,824,088...145,844,402
JBrowse link
G POLR3D RNA polymerase III subunit D IDA (PMID:19631370) UniProtKB PMID:19631370 NCBI chr 8:22,245,104...22,254,601
Ensembl chr 8:22,245,133...22,254,601
JBrowse link
G POLR3F RNA polymerase III subunit F IMP (PMID:19631370) UniProtKB PMID:19631370 NCBI chr20:18,467,390...18,484,646
Ensembl chr20:18,467,389...18,484,646
JBrowse link
G POLR3G RNA polymerase III subunit G IMP (PMID:19609254), (PMID:19631370) UniProtKB PMID:19609254, PMID:19631370 NCBI chr 5:90,473,929...90,514,557
Ensembl chr 5:90,471,748...90,514,557
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISS ARUK-UCL GO_REF:0000024 NCBI chr12:112,418,915...112,509,918
Ensembl chr12:112,418,351...112,509,913
Ensembl chr12:112,418,351...112,509,913
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IEA Ensembl GO_REF:0000107 NCBI chr 1:113,813,811...113,871,761
Ensembl chr 1:113,813,811...113,871,753
JBrowse link
G RIOK3 RIO kinase 3 IMP (PMID:24807708) UniProtKB PMID:24807708 NCBI chr18:23,452,823...23,483,140
Ensembl chr18:23,453,287...23,486,603
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 NAS (PMID:22412986) BHF-UCL PMID:22412986 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064
JBrowse link
G RNF135 ring finger protein 135 IMP (PMID:19017631) UniProtKB PMID:19017631 NCBI chr17:30,968,642...30,999,911
Ensembl chr17:30,970,984...30,999,911
JBrowse link
G TBK1 TANK binding kinase 1 IDA (PMID:16127453) BHF-UCL PMID:16127453 NCBI chr12:64,452,105...64,502,114
Ensembl chr12:64,452,092...64,502,114
JBrowse link
G TICAM1 toll like receptor adaptor molecule 1 IEA Ensembl GO_REF:0000107 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712
JBrowse link
G TLR2 toll like receptor 2 ISS BHF-UCL GO_REF:0000024 NCBI chr 4:153,684,080...153,710,643
Ensembl chr 4:153,684,070...153,706,260
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G TLR3 toll like receptor 3 ISS
IDA
IMP
(PMID:16286015)
(PMID:12054664)
BHF-UCL
UniProt
PMID:12054664, PMID:16286015 GO_REF:0000024 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,069,152...186,088,069
Ensembl chr 4:186,069,152...186,088,069
JBrowse link
G TLR4 toll like receptor 4 ISS BHF-UCL GO_REF:0000024 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TLR7 toll like receptor 7 IDA (PMID:16286015) UniProt PMID:16286015 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361
JBrowse link
G TLR8 toll like receptor 8 IDA (PMID:16286015) UniProt PMID:16286015 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169
JBrowse link
G TLR9 toll like receptor 9 ISS
IDA
(PMID:16286015) BHF-UCL
UniProt
PMID:16286015 GO_REF:0000024 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,226,163
JBrowse link
G ZBTB20 zinc finger and BTB domain containing 20 ISO (MGI:5619432|PMID:23776228) CACAO PMID:23776228 MGI:5619432 NCBI chr 3:114,314,500...115,147,288
Ensembl chr 3:114,314,500...115,147,288
Ensembl chr 3:114,314,500...115,147,288
JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 IDA (PMID:21102435) UniProtKB PMID:21102435 NCBI chr 7:139,043,515...139,109,720
Ensembl chr 7:139,043,515...139,109,720
JBrowse link
G ZFP64 ZFP64 zinc finger protein ISO (MGI:5619431|PMID:23857586) CACAO PMID:23857586 MGI:5619431 NCBI chr20:52,084,011...52,191,789
Ensembl chr20:52,051,663...52,204,308
JBrowse link
positive regulation of type I interferon production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,701
JBrowse link
G CGAS cyclic GMP-AMP synthase TAS
IBA
IDA
(PMID:21873635)
(PMID:24077100), (PMID:26046437), (PMID:28363908), (PMID:28738408)
Reactome
GO_Central
UniProtKB
PMID:21873635, PMID:24077100, PMID:26046437, PMID:28363908, PMID:28738408 Reactome:R-HSA-1834941 NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297
JBrowse link
G CRCP CGRP receptor component TAS Reactome Reactome:R-HSA-1834949 NCBI chr 7:66,114,818...66,154,568
Ensembl chr 7:66,114,604...66,154,568
JBrowse link
G CREBBP CREB binding protein TAS Reactome Reactome:R-HSA-1834949 NCBI chr16:3,725,054...3,880,727
Ensembl chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G CTNNB1 catenin beta 1 TAS Reactome Reactome:R-HSA-1834949 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G DDX41 DEAD-box helicase 41 TAS Reactome Reactome:R-HSA-1834941 NCBI chr 5:177,511,577...177,516,961
Ensembl chr 5:177,511,577...177,516,961
JBrowse link
G DHX33 DEAH-box helicase 33 ISS UniProtKB GO_REF:0000024 NCBI chr17:5,440,917...5,469,055
Ensembl chr17:5,440,917...5,468,982
JBrowse link
G DHX36 DEAH-box helicase 36 TAS Reactome Reactome:R-HSA-1834949 NCBI chr 3:154,272,546...154,324,487
Ensembl chr 3:154,272,546...154,324,487
JBrowse link
G DHX58 DExH-box helicase 58 ISS UniProtKB GO_REF:0000024 NCBI chr17:42,101,404...42,112,721
Ensembl chr17:42,101,404...42,112,714
JBrowse link
G DHX9 DExH-box helicase 9 TAS Reactome Reactome:R-HSA-1834949 NCBI chr 1:182,839,347...182,887,982
Ensembl chr 1:182,839,347...182,887,982
JBrowse link
G EP300 E1A binding protein p300 TAS Reactome Reactome:R-HSA-1834949 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077
JBrowse link
G IFI16 interferon gamma inducible protein 16 TAS Reactome Reactome:R-HSA-1834941 NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 IMP (PMID:23633945) BHF-UCL PMID:23633945 NCBI chr  X:154,010,507...154,019,984
Ensembl chr  X:154,010,506...154,019,902
JBrowse link
G IRF1 interferon regulatory factor 1 ISS UniProtKB GO_REF:0000024 NCBI chr 5:132,481,609...132,490,789
Ensembl chr 5:132,481,609...132,490,777
JBrowse link
G IRF3 interferon regulatory factor 3 TAS
IDA
(PMID:25636800) Reactome
UniProt
PMID:25636800 Reactome:R-HSA-1834949, Reactome:R-HSA-3270619 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G IRF5 interferon regulatory factor 5 IDA (PMID:32433612) UniProt PMID:32433612 NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038
JBrowse link
G IRF7 interferon regulatory factor 7 TAS Reactome Reactome:R-HSA-1834949 NCBI chr11:612,555...615,999
Ensembl chr11:612,553...615,983
JBrowse link
G LRRFIP1 LRR binding FLII interacting protein 1 TAS Reactome Reactome:R-HSA-1834949 NCBI chr 2:237,627,576...237,781,643
Ensembl chr 2:237,627,587...237,813,682
JBrowse link
G MAVS mitochondrial antiviral signaling protein ISO (MGI:3807296|PMID:18780793) MGI PMID:18780793 MGI:3807296 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123
JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease TAS Reactome Reactome:R-HSA-1834949 NCBI chr11:94,415,570...94,512,701
Ensembl chr11:94,415,578...94,493,908
Ensembl chr11:94,415,578...94,493,908
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor TAS
IMP
(PMID:23633945) Reactome
BHF-UCL
PMID:23633945 Reactome:R-HSA-1834949 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,478...38,143,022
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 TAS Reactome Reactome:R-HSA-1834949 NCBI chr 4:102,501,266...102,617,302
Ensembl chr 4:102,501,331...102,617,302
JBrowse link
G NFKB2 nuclear factor kappa B subunit 2 TAS Reactome Reactome:R-HSA-1834949 NCBI chr10:102,394,110...102,402,529
Ensembl chr10:102,394,110...102,402,524
JBrowse link
G PLCG2 phospholipase C gamma 2 IEA Ensembl GO_REF:0000107 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,739,097...81,962,685
JBrowse link
G POLR1C RNA polymerase I and III subunit C TAS Reactome Reactome:R-HSA-1834949 NCBI chr 6:43,517,089...43,562,407
Ensembl chr 6:43,509,702...43,562,419
JBrowse link
G POLR1D RNA polymerase I and III subunit D TAS Reactome Reactome:R-HSA-1834949 NCBI chr13:27,620,743...27,667,415
Ensembl chr13:27,620,742...27,744,237
JBrowse link
G POLR2E RNA polymerase II, I and III subunit E TAS Reactome Reactome:R-HSA-1834949 NCBI chr19:1,086,574...1,095,387
Ensembl chr19:1,086,574...1,095,380
JBrowse link
G POLR2F RNA polymerase II, I and III subunit F TAS Reactome Reactome:R-HSA-1834949 NCBI chr22:37,953,663...38,041,915
Ensembl chr22:37,952,607...38,041,915
JBrowse link
G POLR2H RNA polymerase II, I and III subunit H TAS Reactome Reactome:R-HSA-1834949 NCBI chr 3:184,361,710...184,368,594
Ensembl chr 3:184,361,718...184,368,596
JBrowse link
G POLR2K RNA polymerase II, I and III subunit K TAS Reactome Reactome:R-HSA-1834949 NCBI chr 8:100,150,636...100,154,003
Ensembl chr 8:100,150,623...100,154,003
JBrowse link
G POLR2L RNA polymerase II, I and III subunit L TAS Reactome Reactome:R-HSA-1834949 NCBI chr11:839,721...842,529
Ensembl chr11:837,356...842,529
JBrowse link
G POLR3A RNA polymerase III subunit A TAS Reactome Reactome:R-HSA-1834949 NCBI chr10:77,975,149...78,029,515
Ensembl chr10:77,969,251...78,029,515
JBrowse link
G POLR3B RNA polymerase III subunit B TAS Reactome Reactome:R-HSA-1834949 NCBI chr12:106,357,712...106,510,198
Ensembl chr12:106,357,748...106,510,198
JBrowse link
G POLR3C RNA polymerase III subunit C TAS Reactome Reactome:R-HSA-1834949 NCBI chr 1:145,823,183...145,844,402
Ensembl chr 1:145,824,088...145,844,402
JBrowse link
G POLR3D RNA polymerase III subunit D TAS Reactome Reactome:R-HSA-1834949 NCBI chr 8:22,245,104...22,254,601
Ensembl chr 8:22,245,133...22,254,601
JBrowse link
G POLR3E RNA polymerase III subunit E TAS Reactome Reactome:R-HSA-1834949 NCBI chr16:22,297,409...22,335,096
Ensembl chr16:22,297,375...22,335,101
JBrowse link
G POLR3F RNA polymerase III subunit F TAS Reactome Reactome:R-HSA-1834949 NCBI chr20:18,467,390...18,484,646
Ensembl chr20:18,467,389...18,484,646
JBrowse link
G POLR3G RNA polymerase III subunit G TAS Reactome Reactome:R-HSA-1834949 NCBI chr 5:90,473,929...90,514,557
Ensembl chr 5:90,471,748...90,514,557
JBrowse link
G POLR3GL RNA polymerase III subunit GL TAS Reactome Reactome:R-HSA-1834949 NCBI chr 1:145,959,037...145,978,848
Ensembl chr 1:145,964,690...145,978,848
JBrowse link
G POLR3H RNA polymerase III subunit H TAS Reactome Reactome:R-HSA-1834949 NCBI chr22:41,525,799...41,544,606
Ensembl chr22:41,525,799...41,544,606
JBrowse link
G POLR3K RNA polymerase III subunit K TAS Reactome Reactome:R-HSA-1834949 NCBI chr16:46,407...53,608
Ensembl chr16:46,407...53,608
JBrowse link
G PQBP1 polyglutamine binding protein 1 IDA (PMID:26046437) UniProtKB PMID:26046437 NCBI chr  X:48,897,862...48,903,143
Ensembl chr  X:48,890,197...48,903,143
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit TAS Reactome Reactome:R-HSA-1834949 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178
Ensembl chr 8:47,773,111...47,960,178
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IMP (PMID:23871208) UniProtKB PMID:23871208 NCBI chr 1:113,813,811...113,871,761
Ensembl chr 1:113,813,811...113,871,753
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit TAS Reactome Reactome:R-HSA-1834949 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G STAT6 signal transducer and activator of transcription 6 TAS Reactome Reactome:R-HSA-1834941 NCBI chr12:57,095,408...57,111,413
Ensembl chr12:57,095,408...57,132,139
JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 IEA
IBA
IDA
TAS
(PMID:21873635)
(PMID:22394562), (PMID:23747010), (PMID:26669264), (PMID:29694889), (PMID:30842659)
InterPro
GO_Central
UniProt
Reactome
PMID:21873635, PMID:22394562, PMID:23747010, PMID:26669264, PMID:29694889, PMID:30842659 GO_REF:0000002, Reactome:R-HSA-1834941, Reactome:R-HSA-3270619 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935
JBrowse link
G SYK spleen associated tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549
JBrowse link
G TBK1 TANK binding kinase 1 TAS Reactome Reactome:R-HSA-1834941, Reactome:R-HSA-3270619 NCBI chr12:64,452,105...64,502,114
Ensembl chr12:64,452,092...64,502,114
JBrowse link
G TICAM1 toll like receptor adaptor molecule 1 ISO (MGI:2670551|PMID:12872135) MGI PMID:12872135 MGI:2670551 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712
JBrowse link
G TLR3 toll like receptor 3 ISO (MGI:3774796|PMID:18207576) MGI PMID:18207576 MGI:3774796 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,069,152...186,088,069
Ensembl chr 4:186,069,152...186,088,069
JBrowse link
G TRIM15 tripartite motif containing 15 IMP (PMID:23077300) UniProtKB PMID:23077300 NCBI chr 6:30,163,546...30,172,693
Ensembl chr 6:30,163,206...30,172,693
JBrowse link
G XRCC5 X-ray repair cross complementing 5 TAS Reactome Reactome:R-HSA-1834949 NCBI chr 2:216,109,348...216,206,293
Ensembl chr 2:216,107,464...216,206,303
JBrowse link
G XRCC6 X-ray repair cross complementing 6 TAS Reactome Reactome:R-HSA-1834949 NCBI chr22:41,621,295...41,664,041
Ensembl chr22:41,621,163...41,664,048
Ensembl chr22:41,621,163...41,664,048
JBrowse link
G ZBP1 Z-DNA binding protein 1 TAS Reactome Reactome:R-HSA-1834949 NCBI chr20:57,603,852...57,620,480
Ensembl chr20:57,603,846...57,620,576
JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 ISO (MGI:4868308|PMID:21102435) MGI PMID:21102435 MGI:4868308 NCBI chr 7:139,043,515...139,109,720
Ensembl chr 7:139,043,515...139,109,720
JBrowse link
G ZCCHC3 zinc finger CCHC-type containing 3 IEA Ensembl GO_REF:0000107 NCBI chr20:297,570...300,321
Ensembl chr20:297,570...300,321
JBrowse link
regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF216 ring finger protein 216 IDA (PMID:19893624) UniProtKB PMID:19893624 NCBI chr 7:5,620,047...5,781,721
Ensembl chr 7:5,620,047...5,781,696
Ensembl chr 7:5,620,047...5,781,696
JBrowse link
G TIRAP TIR domain containing adaptor protein ISS BHF-UCL GO_REF:0000024 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,283,065...126,298,845
JBrowse link
G TRAF3 TNF receptor associated factor 3 ISS UniProtKB GO_REF:0000024 NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500
JBrowse link
G TRIM38 tripartite motif containing 38 IEA Ensembl GO_REF:0000107 NCBI chr 6:25,962,723...25,991,231
Ensembl chr 6:25,962,802...25,991,231
JBrowse link
regulation of type I interferon production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CGAS cyclic GMP-AMP synthase ISO (MGI:5699498|PMID:26371324) MGI PMID:26371324 MGI:5699498 NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297
JBrowse link
G DTX4 deltex E3 ubiquitin ligase 4 TAS Reactome Reactome:R-HSA-3134975 NCBI chr11:59,171,430...59,208,588
Ensembl chr11:59,171,430...59,208,588
JBrowse link
G IRF3 interferon regulatory factor 3 TAS Reactome Reactome:R-HSA-3134975 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G IRF7 interferon regulatory factor 7 TAS (PMID:21490621) UniProtKB PMID:21490621 NCBI chr11:612,555...615,999
Ensembl chr11:612,553...615,983
JBrowse link
G IRF8 interferon regulatory factor 8 ISS UniProt GO_REF:0000024 NCBI chr16:85,899,162...85,922,609
Ensembl chr16:85,899,162...85,922,606
JBrowse link
G NLRP4 NLR family pyrin domain containing 4 TAS Reactome Reactome:R-HSA-3134975 NCBI chr19:55,836,540...55,881,855
Ensembl chr19:55,836,540...55,881,855
JBrowse link
G POLA1 DNA polymerase alpha 1, catalytic subunit IMP (PMID:27019227) UniProt PMID:27019227 NCBI chr  X:24,693,877...24,996,986
Ensembl chr  X:24,693,909...24,996,986
JBrowse link
G RNF26 ring finger protein 26 IDA (PMID:25254379) UniProtKB PMID:25254379 NCBI chr11:119,334,527...119,337,309
Ensembl chr11:119,334,527...119,337,309
JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 TAS Reactome Reactome:R-HSA-3134975 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935
JBrowse link
G TBK1 TANK binding kinase 1 TAS
IDA
(PMID:25636800) Reactome
UniProt
PMID:25636800 Reactome:R-HSA-3134975 NCBI chr12:64,452,105...64,502,114
Ensembl chr12:64,452,092...64,502,114
JBrowse link
G TREX1 three prime repair exonuclease 1 TAS Reactome Reactome:R-HSA-3134975 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645
JBrowse link
G TRIM21 tripartite motif containing 21 TAS Reactome Reactome:R-HSA-3134975 NCBI chr11:4,384,897...4,393,702
Ensembl chr11:4,384,897...4,393,702
JBrowse link
G TRIM32 tripartite motif containing 32 TAS Reactome Reactome:R-HSA-3134975 NCBI chr 9:116,687,305...116,701,299
Ensembl chr 9:116,687,302...116,701,300
JBrowse link
G TRIM56 tripartite motif containing 56 TAS Reactome Reactome:R-HSA-3134975 NCBI chr 7:101,085,424...101,097,967
Ensembl chr 7:101,085,481...101,097,967
JBrowse link
G ZBP1 Z-DNA binding protein 1 TAS Reactome Reactome:R-HSA-3134975 NCBI chr20:57,603,852...57,620,480
Ensembl chr20:57,603,846...57,620,576
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18672
    multicellular organismal process 8779
      cytokine production 831
        type I interferon production 133
          interferon-alpha production + 31
          interferon-beta production + 56
          interferon-delta production 0
          interferon-epsilon production 0
          interferon-kappa production 0
          interferon-omega production 0
          interferon-tau production 0
          negative regulation of type I interferon production + 48
          positive regulation of type I interferon production + 81
          regulation of type I interferon production + 133
Path 2
Term Annotations click to browse term
  biological_process 18672
    metabolic process 12302
      organic substance metabolic process 11734
        macromolecule metabolic process 10184
          gene expression 6362
            cytokine production 831
              type I interferon production 133
                interferon-alpha production + 31
                interferon-beta production + 56
                interferon-delta production 0
                interferon-epsilon production 0
                interferon-kappa production 0
                interferon-omega production 0
                interferon-tau production 0
                negative regulation of type I interferon production + 48
                positive regulation of type I interferon production + 81
                regulation of type I interferon production + 133
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.