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ONTOLOGY REPORT - ANNOTATIONS


Term:type I interferon production
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Accession:GO:0032606 term browser browse the term
Definition:The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
Comment:Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
Synonyms:exact_synonym: type I IFN production
 narrow_synonym: type I interferon biosynthetic process;   type I interferon secretion
 alt_id: GO:0045351;   GO:0072641


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negative regulation of interferon-alpha production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gbp4 guanylate binding protein 4 IMP (MGI:5306181|PMID:22095711) MGI PMID:22095711 MGI:5306181 NCBI chr 5:105,115,767...105,139,586
Ensembl chr 5:105,115,767...105,139,586
JBrowse link
G Gm14548 predicted gene 14548 ISO (PMID:16735691) UniProtKB PMID:16735691 NCBI chr 7:3,884,201...3,898,159
Ensembl chr 7:3,884,242...3,898,120
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr11:46,454,931...46,481,255
Ensembl chr11:46,454,935...46,481,255
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 IMP (MGI:5568884|PMID:24560620) UniProt PMID:24560620 MGI:5568884 NCBI chr16:3,943,807...3,979,017
Ensembl chr16:3,945,007...3,976,632
JBrowse link
G Nmi N-myc (and STAT) interactor IMP (MGI:5546557|PMID:23956435) MGI PMID:23956435 MGI:5546557 NCBI chr 2:51,948,498...51,973,489
Ensembl chr 2:51,948,487...51,973,494
JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr17:56,412,426...56,476,561
Ensembl chr17:56,412,426...56,476,483
JBrowse link
negative regulation of interferon-beta production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg9a autophagy related 9A IMP (MGI:5569198|PMID:24670807) MGI PMID:24670807 MGI:5569198 NCBI chr 1:75,180,861...75,192,010
Ensembl chr 1:75,180,860...75,192,196
JBrowse link
G Cactin cactin, spliceosome C complex subunit ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr10:81,321,103...81,326,251
Ensembl chr10:81,321,103...81,326,242
JBrowse link
G Crebbp CREB binding protein IMP (MGI:2151262|PMID:11583620) CAFA PMID:11583620 MGI:2151262 NCBI chr16:4,081,334...4,213,957
Ensembl chr16:4,081,328...4,213,997
JBrowse link
G Irf3 interferon regulatory factor 3 IDA (MGI:3828224|PMID:18851954) MGI PMID:18851954 MGI:3828224 NCBI chr 7:44,997,648...45,002,848
Ensembl chr 7:44,997,648...45,002,848
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 IMP (MGI:5568884|PMID:24560620) UniProt PMID:24560620 MGI:5568884 NCBI chr16:3,943,807...3,979,017
Ensembl chr16:3,945,007...3,976,632
JBrowse link
G Nlrx1 NLR family member X1 IMP (MGI:5050761|PMID:21703540) MGI PMID:21703540 MGI:5050761 NCBI chr 9:44,252,713...44,268,599
Ensembl chr 9:44,252,717...44,268,599
JBrowse link
G Nmi N-myc (and STAT) interactor IMP (MGI:5546557|PMID:23956435) MGI PMID:23956435 MGI:5546557 NCBI chr 2:51,948,498...51,973,489
Ensembl chr 2:51,948,487...51,973,494
JBrowse link
G Ppm1b protein phosphatase 1B, magnesium dependent, beta isoform ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr17:84,956,741...85,023,992
Ensembl chr17:84,956,741...85,023,991
JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr17:56,412,426...56,476,561
Ensembl chr17:56,412,426...56,476,483
JBrowse link
G Pycard PYD and CARD domain containing ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 7:127,991,373...127,993,867
Ensembl chr 7:127,989,708...127,993,867
JBrowse link
G Rel reticuloendotheliosis oncogene ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr11:23,736,847...23,770,969
Ensembl chr11:23,736,847...23,770,970
JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 7:19,606,217...19,629,438
Ensembl chr 7:19,606,217...19,629,438
JBrowse link
G Sirpa signal-regulatory protein alpha IMP (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chr 2:129,591,042...129,632,228
Ensembl chr 2:129,592,835...129,632,228
JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 IMP (MGI:5306204|PMID:22079989) MGI PMID:22079989 MGI:5306204 NCBI chr 1:91,494,590...91,529,307
Ensembl chr 1:91,494,647...91,529,307
JBrowse link
G Traip TRAF-interacting protein IDA (MGI:5619447|PMID:22945920) CACAO PMID:22945920 MGI:5619447 NCBI chr 9:107,950,325...107,972,270
Ensembl chr 9:107,950,136...107,972,270
JBrowse link
G Yy1 YY1 transcription factor ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr12:108,792,945...108,820,148
Ensembl chr12:108,792,973...108,820,148
JBrowse link
negative regulation of type I interferon production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 IMP (MGI:5490396|PMID:23609450) UniProt PMID:23609450 MGI:5490396 NCBI chr14:103,047,012...103,056,573
Ensembl chr14:103,046,977...103,056,573
JBrowse link
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 ISO
IMP
(MGI:5318004|PMID:21525357) MGI
UniProt
PMID:21525357 GO_REF:0000096, MGI:4834177, MGI:5318004 NCBI chr11:100,694,884...100,704,271
Ensembl chr11:100,694,884...100,704,271
JBrowse link
G Gpatch3 G patch domain containing 3 IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096, MGI:4834177, MGI:6201960 NCBI chr 4:133,574,745...133,584,242
Ensembl chr 4:133,574,745...133,584,243
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 IMP (MGI:5437532|PMID:22842346) UniProt PMID:22842346 MGI:5437532 NCBI chr11:46,454,931...46,481,255
Ensembl chr11:46,454,935...46,481,255
JBrowse link
G Ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr17:27,751,232...27,820,542
Ensembl chr17:27,751,235...27,820,648
JBrowse link
G Nmi N-myc (and STAT) interactor IGI (MGI:5546557|PMID:23956435) MGI PMID:23956435 MGI:5546557 NCBI chr 2:51,948,498...51,973,489
Ensembl chr 2:51,948,487...51,973,494
JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr11:120,379,798...120,437,700
Ensembl chr11:120,380,370...120,437,708
JBrowse link
G Peli3 pellino 3 IMP (MGI:5441107|PMID:23042151) MGI PMID:23042151 MGI:5441107 NCBI chr19:4,929,717...4,943,127
Ensembl chr19:4,929,717...4,943,127
JBrowse link
G Rnf125 ring finger protein 125 ISO (PMID:17460044), (PMID:26471729) UniProtKB PMID:17460044, PMID:26471729 NCBI chr18:20,944,615...20,987,359
Ensembl chr18:20,944,625...20,983,862
JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 1:91,494,590...91,529,307
Ensembl chr 1:91,494,647...91,529,307
JBrowse link
G Ufd1 ubiquitin recognition factor in ER-associated degradation 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr16:18,811,736...18,835,261
Ensembl chr16:18,811,779...18,835,261
JBrowse link
positive regulation of interferon-alpha production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chuk conserved helix-loop-helix ubiquitous kinase ISO
IMP
(MGI:5583923|PMID:24784232) MGI
CAFA
PMID:24784232 GO_REF:0000096, MGI:4834177, MGI:5583923 NCBI chr19:44,073,334...44,107,505
Ensembl chr19:44,073,335...44,107,480
JBrowse link
G Ddx3x DEAD box helicase 3, X-linked ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr  X:13,280,496...13,293,988
Ensembl chr  X:13,280,970...13,294,052
JBrowse link
G Ddx58 DEAD/H box helicase 58 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 4:40,203,777...40,239,825
Ensembl chr 4:40,203,773...40,239,828
JBrowse link
G Dhx36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 3:62,468,015...62,507,034
Ensembl chr 3:62,468,013...62,507,004
JBrowse link
G Dhx9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 1:153,455,756...153,487,688
Ensembl chr 1:153,455,758...153,487,660
JBrowse link
G Flt3 FMS-like tyrosine kinase 3 IMP (MGI:4452060|PMID:20457904) MGI PMID:20457904 MGI:4452060 NCBI chr 5:147,330,741...147,400,489
Ensembl chr 5:147,330,741...147,400,489
JBrowse link
G Hmgb1 high mobility group box 1 IMP (MGI:4367121|PMID:19890330) UniProt PMID:19890330 MGI:4367121 NCBI chr 5:149,046,702...149,053,057
Ensembl chr 5:149,046,702...149,184,489
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) IDA
ISO
IBA
(MGI:3708392|PMID:17164250)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:17164250, PMID:21873635 GO_REF:0000096, MGI:3708392, MGI:4834177, MGI:6201960 NCBI chr 1:55,077,833...55,088,243
Ensembl chr 1:55,077,835...55,088,243
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 2:62,595,618...62,646,255
Ensembl chr 2:62,595,798...62,646,255
JBrowse link
G Irf3 interferon regulatory factor 3 IMP (MGI:4365354|PMID:18562536) UniProt PMID:18562536 MGI:4365354 NCBI chr 7:44,997,648...45,002,848
Ensembl chr 7:44,997,648...45,002,848
JBrowse link
G Irf7 interferon regulatory factor 7 TAS
ISO
(MGI:5320281|PMID:16979567) UniProt
MGI
PMID:16979567 GO_REF:0000096, MGI:4834177, MGI:5320281 NCBI chr 7:141,263,183...141,266,499
Ensembl chr 7:141,262,706...141,266,481
JBrowse link
G Mavs mitochondrial antiviral signaling protein ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 2:131,234,063...131,248,025
Ensembl chr 2:131,234,063...131,248,025
JBrowse link
G Mmp12 matrix metallopeptidase 12 IMP (MGI:5583923|PMID:24784232) CAFA PMID:24784232 MGI:5583923 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) IMP (MGI:5562517|PMID:23871208) UniProt PMID:23871208 MGI:5562517 NCBI chr 3:103,856,575...103,912,252
Ensembl chr 3:103,859,795...103,912,247
JBrowse link
G Setd2 SET domain containing 2 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 9:110,532,500...110,618,633
Ensembl chr 9:110,532,597...110,618,633
JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 1:52,119,438...52,161,865
Ensembl chr 1:52,119,440...52,161,865
JBrowse link
G Tbk1 TANK-binding kinase 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr10:121,546,455...121,586,794
Ensembl chr10:121,546,455...121,586,787
JBrowse link
G Tlr3 toll-like receptor 3 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 8:45,395,665...45,411,075
Ensembl chr 8:45,395,665...45,411,080
JBrowse link
G Tlr4 toll-like receptor 4 IDA (MGI:4456948|PMID:15356140) BHF-UCL PMID:15356140 MGI:4456948 NCBI chr 4:66,827,551...66,846,581
Ensembl chr 4:66,827,584...66,930,284
JBrowse link
G Tlr7 toll-like receptor 7 ISO
IMP
(MGI:3042320|PMID:14976261) MGI
UniProt
PMID:14976261 GO_REF:0000096, MGI:3042320, MGI:4834177 NCBI chr  X:167,303,380...167,330,574
Ensembl chr  X:167,304,929...167,330,558
JBrowse link
G Tlr8 toll-like receptor 8 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr  X:167,241,123...167,264,329
Ensembl chr  X:167,242,696...167,264,329
JBrowse link
G Tlr9 toll-like receptor 9 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 9:106,222,598...106,226,876
Ensembl chr 9:106,222,598...106,226,883
JBrowse link
G Zc3hav1 zinc finger CCCH type, antiviral 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 6:38,305,286...38,355,352
Ensembl chr 6:38,305,286...38,354,603
JBrowse link
positive regulation of interferon-beta production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD box helicase 3, X-linked ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr  X:13,280,496...13,293,988
Ensembl chr  X:13,280,970...13,294,052
JBrowse link
G Ddx58 DEAD/H box helicase 58 ISO
IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:5318026|PMID:17942531)
MGI
GO_Central
UniProt
PMID:17942531, PMID:21873635 GO_REF:0000096, MGI:4834177, MGI:5318026, MGI:6201960 NCBI chr 4:40,203,777...40,239,825
Ensembl chr 4:40,203,773...40,239,828
JBrowse link
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr11:100,694,884...100,704,271
Ensembl chr11:100,694,884...100,704,271
JBrowse link
G Dhx9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 1:153,455,756...153,487,688
Ensembl chr 1:153,455,758...153,487,660
JBrowse link
G Flot1 flotillin 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr17:35,823,320...35,832,789
Ensembl chr17:35,823,230...35,832,791
JBrowse link
G Hmgb1 high mobility group box 1 IMP (MGI:4367121|PMID:19890330) UniProt PMID:19890330 MGI:4367121 NCBI chr 5:149,046,702...149,053,057
Ensembl chr 5:149,046,702...149,184,489
JBrowse link
G Hmgb2 high mobility group box 2 IMP (MGI:4367121|PMID:19890330) UniProt PMID:19890330 MGI:4367121 NCBI chr 8:57,511,843...57,515,999
Ensembl chr 8:57,511,907...57,515,999
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096, MGI:4834177, MGI:6201960 NCBI chr 2:62,595,618...62,646,255
Ensembl chr 2:62,595,798...62,646,255
JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 IMP (MGI:5619426|PMID:24598055) CACAO PMID:24598055 MGI:5619426 NCBI chr16:91,485,032...91,510,523
Ensembl chr16:91,485,238...91,507,441
JBrowse link
G Irf1 interferon regulatory factor 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr11:53,770,014...53,778,374
Ensembl chr11:53,770,014...53,778,374
JBrowse link
G Irf3 interferon regulatory factor 3 IMP
TAS
(MGI:4365354|PMID:18562536)
(MGI:5320281|PMID:16979567)
UniProt PMID:16979567, PMID:18562536 MGI:4365354, MGI:5320281 NCBI chr 7:44,997,648...45,002,848
Ensembl chr 7:44,997,648...45,002,848
JBrowse link
G Irf7 interferon regulatory factor 7 ISO
TAS
(MGI:5320281|PMID:16979567) MGI
UniProt
PMID:16979567 GO_REF:0000096, MGI:4834177, MGI:5320281 NCBI chr 7:141,263,183...141,266,499
Ensembl chr 7:141,262,706...141,266,481
JBrowse link
G Mavs mitochondrial antiviral signaling protein ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 2:131,234,063...131,248,025
Ensembl chr 2:131,234,063...131,248,025
JBrowse link
G Polr3a polymerase (RNA) III (DNA directed) polypeptide A ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr14:24,448,694...24,487,070
Ensembl chr14:24,448,696...24,487,058
JBrowse link
G Polr3b polymerase (RNA) III (DNA directed) polypeptide B ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr10:84,622,292...84,727,178
Ensembl chr10:84,622,292...84,727,178
JBrowse link
G Polr3c polymerase (RNA) III (DNA directed) polypeptide C ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 3:96,711,520...96,727,498
Ensembl chr 3:96,711,490...96,727,628
JBrowse link
G Polr3d polymerase (RNA) III (DNA directed) polypeptide D ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr14:70,438,748...70,443,471
Ensembl chr14:70,438,757...70,443,447
JBrowse link
G Polr3f polymerase (RNA) III (DNA directed) polypeptide F ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 2:144,527,745...144,541,779
Ensembl chr 2:144,527,718...144,541,995
JBrowse link
G Polr3g polymerase (RNA) III (DNA directed) polypeptide G ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr13:81,673,837...81,711,013
Ensembl chr13:81,673,843...81,711,013
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 IMP (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chr 5:121,130,533...121,191,397
Ensembl chr 5:121,130,533...121,191,397
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) IMP (MGI:5562517|PMID:23871208) UniProt PMID:23871208 MGI:5562517 NCBI chr 3:103,856,575...103,912,252
Ensembl chr 3:103,859,795...103,912,247
JBrowse link
G Riok3 RIO kinase 3 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr18:12,126,091...12,157,367
Ensembl chr18:12,128,741...12,157,387
JBrowse link
G Rnf135 ring finger protein 135 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr11:80,183,869...80,199,755
Ensembl chr11:80,183,851...80,199,757
JBrowse link
G Tbk1 TANK-binding kinase 1 IMP
ISO
(MGI:3530402|PMID:15661922) MGI PMID:15661922 GO_REF:0000096, MGI:3530402, MGI:4834177 NCBI chr10:121,546,455...121,586,794
Ensembl chr10:121,546,455...121,586,787
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 IMP (MGI:2669022|PMID:12855817)
(MGI:2670551|PMID:12872135)
MGI PMID:12855817, PMID:12872135 MGI:2669022, MGI:2670551 NCBI chr17:56,269,462...56,276,767
Ensembl chr17:56,269,319...56,276,786
JBrowse link
G Tlr2 toll-like receptor 2 IDA (MGI:4456948|PMID:15356140) BHF-UCL PMID:15356140 MGI:4456948 NCBI chr 3:83,836,272...83,841,824
Ensembl chr 3:83,836,272...83,841,767
JBrowse link
G Tlr3 toll-like receptor 3 ISS
ISO
IDA
(MGI:3687930|PMID:12054664)
(MGI:4456948|PMID:15356140)
UniProt
MGI
BHF-UCL
PMID:12054664, PMID:15356140 GO_REF:0000096, MGI:3687930, MGI:4456948, MGI:4834177 NCBI chr 8:45,395,665...45,411,075
Ensembl chr 8:45,395,665...45,411,080
JBrowse link
G Tlr4 toll-like receptor 4 IMP
IDA
(MGI:3530402|PMID:15661922)
(MGI:4456948|PMID:15356140)
MGI
BHF-UCL
PMID:15356140, PMID:15661922 MGI:3530402, MGI:4456948 NCBI chr 4:66,827,551...66,846,581
Ensembl chr 4:66,827,584...66,930,284
JBrowse link
G Tlr7 toll-like receptor 7 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr  X:167,303,380...167,330,574
Ensembl chr  X:167,304,929...167,330,558
JBrowse link
G Tlr8 toll-like receptor 8 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr  X:167,241,123...167,264,329
Ensembl chr  X:167,242,696...167,264,329
JBrowse link
G Tlr9 toll-like receptor 9 IDA
ISO
(MGI:4456948|PMID:15356140) BHF-UCL
MGI
PMID:15356140 GO_REF:0000096, MGI:4456948, MGI:4834177 NCBI chr 9:106,222,598...106,226,876
Ensembl chr 9:106,222,598...106,226,883
JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 IMP
IDA
(MGI:5619432|PMID:23776228) CACAO PMID:23776228 MGI:5619432 NCBI chr16:42,875,689...43,634,392
Ensembl chr16:42,875,881...43,642,602
JBrowse link
G Zc3hav1 zinc finger CCCH type, antiviral 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 6:38,305,286...38,355,352
Ensembl chr 6:38,305,286...38,354,603
JBrowse link
G Zfp64 zinc finger protein 64 IMP
IDA
(MGI:5619431|PMID:23857586) CACAO PMID:23857586 MGI:5619431 NCBI chr 2:168,893,331...168,955,587
Ensembl chr 2:168,893,331...168,955,587
JBrowse link
positive regulation of type I interferon production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 antigen IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:5300392|PMID:22078883)
GO_Central
CACAO
PMID:21873635, PMID:22078883 MGI:5300392, MGI:6201960 NCBI chr18:36,725,064...36,726,815
Ensembl chr18:36,725,067...36,726,798
JBrowse link
G Cgas cyclic GMP-AMP synthase ISO
IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:5908326|PMID:24077100), (MGI:5909141|PMID:28759889), (MGI:5909142|PMID:28759028)
MGI
GO_Central
UniProt
PMID:21873635, PMID:24077100, PMID:28759028, PMID:28759889 GO_REF:0000096, MGI:4834177, MGI:5908326, MGI:5909141, MGI:5909142, MGI:6201960 NCBI chr 9:78,430,518...78,443,237
Ensembl chr 9:78,430,526...78,443,237
JBrowse link
G Dhx33 DEAH (Asp-Glu-Ala-His) box polypeptide 33 IMP (MGI:6120210|PMID:24037184) UniProt PMID:24037184 MGI:6120210 NCBI chr11:70,984,091...71,004,533
Ensembl chr11:70,984,091...71,004,437
JBrowse link
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 IMP (MGI:4421606|PMID:20080593) UniProt PMID:20080593 MGI:4421606 NCBI chr11:100,694,884...100,704,271
Ensembl chr11:100,694,884...100,704,271
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr  X:74,013,914...74,023,921
Ensembl chr  X:74,013,914...74,023,918
JBrowse link
G Irf1 interferon regulatory factor 1 IMP (MGI:3691368|PMID:17018642) UniProt PMID:17018642 MGI:3691368 NCBI chr11:53,770,014...53,778,374
Ensembl chr11:53,770,014...53,778,374
JBrowse link
G Irf3 interferon regulatory factor 3 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 7:44,997,648...45,002,848
Ensembl chr 7:44,997,648...45,002,848
JBrowse link
G Irf5 interferon regulatory factor 5 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 6:29,526,130...29,541,869
Ensembl chr 6:29,526,625...29,541,871
JBrowse link
G Irf7 interferon regulatory factor 7 IGI (MGI:5546557|PMID:23956435) MGI PMID:23956435 MGI:5546557 NCBI chr 7:141,263,183...141,266,499
Ensembl chr 7:141,262,706...141,266,481
JBrowse link
G Mavs mitochondrial antiviral signaling protein IMP (MGI:3807296|PMID:18780793) MGI PMID:18780793 MGI:3807296 NCBI chr 2:131,234,063...131,248,025
Ensembl chr 2:131,234,063...131,248,025
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 9:119,335,934...119,340,018
Ensembl chr 9:119,335,934...119,341,411
JBrowse link
G Plcg2 phospholipase C, gamma 2 IMP (MGI:5300392|PMID:22078883) CACAO PMID:22078883 MGI:5300392 NCBI chr 8:117,498,275...117,635,142
Ensembl chr 8:117,498,291...117,635,142
JBrowse link
G Pqbp1 polyglutamine binding protein 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr  X:7,894,519...7,899,269
Ensembl chr  X:7,894,519...7,899,269
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 3:103,856,575...103,912,252
Ensembl chr 3:103,859,795...103,912,247
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 ISO
IDA
IBA
(MGI:5787716|PMID:26669264)
(MGI:6201960|PMID:21873635)
MGI
UniProt
GO_Central
PMID:21873635, PMID:26669264 GO_REF:0000096, MGI:4417868, MGI:4834177, MGI:5787716, MGI:6201960 NCBI chr18:35,733,678...35,740,554
Ensembl chr18:35,733,679...35,740,554
JBrowse link
G Syk spleen tyrosine kinase IMP (MGI:5300392|PMID:22078883) CACAO PMID:22078883 MGI:5300392 NCBI chr13:52,582,610...52,648,792
Ensembl chr13:52,583,173...52,648,792
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 IMP (MGI:2670551|PMID:12872135) MGI PMID:12872135 MGI:2670551 NCBI chr17:56,269,462...56,276,767
Ensembl chr17:56,269,319...56,276,786
JBrowse link
G Tlr3 toll-like receptor 3 IDA (MGI:3774796|PMID:18207576) MGI PMID:18207576 MGI:3774796 NCBI chr 8:45,395,665...45,411,075
Ensembl chr 8:45,395,665...45,411,080
JBrowse link
G Trim15 tripartite motif-containing 15 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr17:36,860,690...36,867,367
Ensembl chr17:36,860,691...36,867,210
JBrowse link
G Zc3hav1 zinc finger CCCH type, antiviral 1 IDA (MGI:4868308|PMID:21102435) MGI PMID:21102435 MGI:4868308 NCBI chr 6:38,305,286...38,355,352
Ensembl chr 6:38,305,286...38,354,603
JBrowse link
G Zcchc3 zinc finger, CCHC domain containing 3 IMP (MGI:6209107|PMID:30135424) UniProt PMID:30135424 MGI:6209107 NCBI chr 2:152,411,956...152,415,044
Ensembl chr 2:152,411,955...152,415,027
JBrowse link
regulation of interferon-beta production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf216 ring finger protein 216 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 5:142,990,893...143,113,041
Ensembl chr 5:142,990,893...143,112,994
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 NOT ISO (MGI:2667507|PMID:12721283) MGI PMID:12721283 MGI:2667507 NCBI chr18:46,558,231...46,574,533
Ensembl chr18:46,557,291...46,574,533
JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein IDA (MGI:4942245|PMID:14630816) BHF-UCL PMID:14630816 MGI:4942245 NCBI chr 9:35,184,391...35,200,291
Ensembl chr 9:35,184,551...35,200,291
JBrowse link
G Traf3 TNF receptor-associated factor 3 IMP (MGI:4839450|PMID:16306937) UniProt PMID:16306937 MGI:4839450 NCBI chr12:111,166,321...111,267,155
Ensembl chr12:111,166,370...111,267,153
JBrowse link
G Trim38 tripartite motif-containing 38 IMP
IDA
(MGI:5441682|PMID:22539786) MGI PMID:22539786 MGI:5441682 NCBI chr13:23,778,500...23,791,731
Ensembl chr13:23,769,913...23,791,528
JBrowse link
regulation of type I interferon production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase IGI (MGI:5699498|PMID:26371324) MGI PMID:26371324 MGI:5699498 NCBI chr 9:78,430,518...78,443,237
Ensembl chr 9:78,430,526...78,443,237
JBrowse link
G Irf8 interferon regulatory factor 8 IMP (MGI:3654212|PMID:12461077) UniProt PMID:12461077 MGI:3654212 NCBI chr 8:120,736,358...120,756,694
Ensembl chr 8:120,736,358...120,756,694
JBrowse link
G Pola1 polymerase (DNA directed), alpha 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr  X:93,304,766...93,632,387
Ensembl chr  X:93,304,767...93,632,155
JBrowse link
G Rnf26 ring finger protein 26 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 9:44,110,781...44,113,051
Ensembl chr 9:44,095,631...44,113,517
Ensembl chr 9:44,095,631...44,113,517
JBrowse link
G Tbk1 TANK-binding kinase 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr10:121,546,455...121,586,794
Ensembl chr10:121,546,455...121,586,787
JBrowse link
G Trex1 three prime repair exonuclease 1 IMP
IGI
(MGI:5523362|PMID:24154727)
(MGI:4848004|PMID:20871604)
(MGI:5699498|PMID:26371324)
MGI PMID:20871604, PMID:24154727, PMID:26371324 MGI:4848004, MGI:5523362, MGI:5699498 NCBI chr 9:109,057,932...109,059,723
Ensembl chr 9:109,057,933...109,059,734
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23387
    multicellular organismal process 8883
      cytokine production 764
        type I interferon production 87
          interferon-alpha production + 29
          interferon-beta production + 54
          interferon-delta production 0
          interferon-epsilon production 0
          interferon-kappa production 0
          interferon-omega production 0
          interferon-tau production 0
          negative regulation of type I interferon production + 27
          positive regulation of type I interferon production + 53
          regulation of type I interferon production + 87
Path 2
Term Annotations click to browse term
  biological_process 23387
    metabolic process 11211
      organic substance metabolic process 10656
        macromolecule metabolic process 9152
          gene expression 5864
            cytokine production 764
              type I interferon production 87
                interferon-alpha production + 29
                interferon-beta production + 54
                interferon-delta production 0
                interferon-epsilon production 0
                interferon-kappa production 0
                interferon-omega production 0
                interferon-tau production 0
                negative regulation of type I interferon production + 27
                positive regulation of type I interferon production + 53
                regulation of type I interferon production + 87
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.