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ONTOLOGY REPORT - ANNOTATIONS


Term:interferon-beta production
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Accession:GO:0032608 term browser browse the term
Definition:The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: IFN-beta production;   IFNB production
 narrow_synonym: interferon-beta biosynthetic process;   interferon-beta secretion
 alt_id: GO:0035546;   GO:0045350


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interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf7 interferon regulatory factor 7 ISO (MGI:MGI:3575992|PMID:15800576) RGD PMID:15800576 MGI:MGI:3575992 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 ISS
ISO
GO_REF:0000024
(MGI:MGI:3849536|PMID:19433799), (MGI:MGI:4365649|PMID:19776740)
(PMID:19433799), (PMID:21074459), (PMID:25254379)
UniProt
RGD
PMID:19433799, PMID:19776740, PMID:21074459, PMID:25254379 GO_REF:0000024, MGI:MGI:3849536, MGI:MGI:4365649 NCBI chr18:28,529,537...28,535,828
Ensembl chr18:28,529,576...28,535,828
JBrowse link
negative regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg9a autophagy related 9A ISO (MGI:MGI:5569198|PMID:24670807) RGD PMID:24670807 MGI:MGI:5569198 NCBI chr 9:82,382,800...82,393,429
Ensembl chr 9:82,382,800...82,393,382
JBrowse link
G Cactin cactin, spliceosome C complex subunit ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:11,258,526...11,266,509
Ensembl chr 7:11,261,201...11,266,630
JBrowse link
G Crebbp CREB binding protein ISO (MGI:MGI:2151262|PMID:11583620) RGD PMID:11583620 MGI:MGI:2151262 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Irf3 interferon regulatory factor 3 ISO (MGI:MGI:3828224|PMID:18851954) RGD PMID:18851954 MGI:MGI:3828224 NCBI chr 1:100,992,244...100,997,202
Ensembl chr 1:100,992,405...100,997,198
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 ISO (MGI:MGI:5568884|PMID:24560620) RGD PMID:24560620 MGI:MGI:5568884 NCBI chr10:11,809,531...11,844,184
Ensembl chr10:11,810,926...11,842,482
JBrowse link
G Nlrx1 NLR family member X1 ISO
IEA
MGI:MGI:5141085 (MGI:MGI:5050761|PMID:21703540)
GO_REF:0000107
RGD
Ensembl
PMID:21703540 GO_REF:0000107, MGI:MGI:5050761 NCBI chr 8:48,583,559...48,600,203
Ensembl chr 8:48,584,071...48,597,867
JBrowse link
G Nmi N-myc (and STAT) interactor ISO (MGI:MGI:5546557|PMID:23956435) RGD PMID:23956435 MGI:MGI:5546557 NCBI chr 3:37,458,891...37,480,984
Ensembl chr 3:37,458,890...37,480,984
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B ISO
ISS
(PMID:22750291)
GO_REF:0000024
RGD
UniProt
PMID:22750291 GO_REF:0000024 NCBI chr 6:8,219,385...8,280,127
Ensembl chr 6:8,218,696...8,280,124
JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S IEA
ISO
GO_REF:0000107
(PMID:26231120)
Ensembl
RGD
PMID:26231120 GO_REF:0000107 NCBI chr 9:10,585,360...10,646,205
Ensembl chr 9:10,603,813...10,645,939
JBrowse link
G Pycard PYD and CARD domain containing ISO (PMID:19158675) RGD PMID:19158675 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit ISO (PMID:22065573) RGD PMID:22065573 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit ISO (PMID:22065573) RGD PMID:22065573 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G Sirpa signal-regulatory protein alpha ISO
IEA
(MGI:MGI:3760575|PMID:17954568)
GO_REF:0000107
RGD
Ensembl
PMID:17954568 GO_REF:0000107, MGI:MGI:3760575 NCBI chr 3:122,113,735...122,152,478
Ensembl chr 3:122,114,108...122,152,477
JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 ISO (MGI:MGI:5306204|PMID:22079989) RGD PMID:22079989 MGI:MGI:5306204 NCBI chr 9:98,621,499...98,658,223
Ensembl chr 9:98,621,506...98,656,901
JBrowse link
G Traip TRAF-interacting protein ISO (MGI:MGI:5619447|PMID:22945920) RGD PMID:22945920 MGI:MGI:5619447 NCBI chr 8:116,730,170...116,750,528
Ensembl chr 8:116,730,641...116,750,709
JBrowse link
G Yy1 YY1 transcription factor ISO (PMID:16260628) RGD PMID:16260628 NCBI chr 6:132,702,443...132,726,848
Ensembl chr 6:132,702,448...132,727,046
JBrowse link
positive regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked ISO (PMID:27980081), (PMID:31575075) RGD PMID:27980081, PMID:31575075 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Ddx58 DEXD/H-box helicase 58 ISO
IBA
(MGI:MGI:5318026|PMID:17942531)
(PMID:17079289), (PMID:19211564), (PMID:19609254), (PMID:19631370), (PMID:21957149)
PMID:21873635
RGD PMID:17079289, PMID:17942531, PMID:19211564, PMID:19609254, PMID:19631370, PMID:21957149, PMID:21873635 MGI:MGI:5318026, RGD:13792537 NCBI chr 5:56,486,584...56,536,898
Ensembl chr 5:56,500,734...56,536,772
JBrowse link
G Dhx58 DEXH-box helicase 58 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:88,599,722...88,611,562
Ensembl chr10:88,599,680...88,611,105
JBrowse link
G Dhx9 DExH-box helicase 9 ISO (PMID:21957149) RGD PMID:21957149 NCBI chr13:70,885,503...70,922,278
Ensembl chr13:70,885,504...70,922,245
JBrowse link
G Flot1 flotillin 1 ISO (PMID:25204797) RGD PMID:25204797 NCBI chr20:3,427,890...3,438,418
Ensembl chr20:3,427,880...3,438,396
JBrowse link
G Hmgb1 high mobility group box 1 ISO (MGI:MGI:4367121|PMID:19890330) RGD PMID:19890330 MGI:MGI:4367121 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgb2 high mobility group box 2 ISO (MGI:MGI:4367121|PMID:19890330) RGD PMID:19890330 MGI:MGI:4367121 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 IBA
ISO
PMID:21873635
(PMID:17600090), (PMID:19211564), (PMID:19656871), (PMID:21957149)
RGD PMID:17600090, PMID:19211564, PMID:19656871, PMID:21957149, PMID:21873635 RGD:13792537 NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097
JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 ISO (MGI:MGI:5619426|PMID:24598055) RGD PMID:24598055 MGI:MGI:5619426 NCBI chr11:31,640,407...31,666,839
Ensembl chr11:31,640,407...31,664,061
JBrowse link
G Irf1 interferon regulatory factor 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:21389130)
Ensembl
UniProt
RGD
PMID:21389130 GO_REF:0000024, GO_REF:0000107 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Irf3 interferon regulatory factor 3 ISO (MGI:MGI:4365354|PMID:18562536) RGD PMID:18562536 MGI:MGI:4365354 NCBI chr 1:100,992,244...100,997,202
Ensembl chr 1:100,992,405...100,997,198
JBrowse link
G Irf7 interferon regulatory factor 7 ISO (PMID:22065573) RGD PMID:22065573 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Mavs mitochondrial antiviral signaling protein ISS
ISO
GO_REF:0000024
(PMID:16127453), (PMID:19609254), (PMID:19631370), (PMID:21957149)
UniProt
RGD
PMID:16127453, PMID:19609254, PMID:19631370, PMID:21957149 GO_REF:0000024 NCBI chr 3:123,776,147...123,790,572
Ensembl chr 3:123,776,181...123,790,567
JBrowse link
G Polr3a RNA polymerase III subunit A ISO (PMID:19609254) RGD PMID:19609254 NCBI chr16:717,821...756,002
Ensembl chr16:716,683...755,990
JBrowse link
G Polr3b RNA polymerase III subunit B ISO (PMID:19609254) RGD PMID:19609254 NCBI chr 7:24,745,051...24,851,227
Ensembl chr 7:24,745,051...24,851,227
JBrowse link
G Polr3c RNA polymerase III subunit C ISO
ISS
(PMID:19609254)
GO_REF:0000024
RGD
UniProt
PMID:19609254 GO_REF:0000024 NCBI chr 2:198,836,282...198,852,368
Ensembl chr 2:198,836,285...198,852,161
JBrowse link
G Polr3d RNA polymerase III subunit D ISO (PMID:19631370) RGD PMID:19631370 NCBI chr15:52,129,471...52,134,140
Ensembl chr15:52,129,471...52,134,140
JBrowse link
G Polr3f RNA polymerase III subunit F ISO (PMID:19631370) RGD PMID:19631370 NCBI chr 3:138,684,685...138,701,055
Ensembl chr 3:138,684,685...138,701,055
JBrowse link
G Polr3g RNA polymerase III subunit G ISO (PMID:19609254), (PMID:19631370) RGD PMID:19609254, PMID:19631370 NCBI chr 2:9,537,642...9,578,551
Ensembl chr 2:9,537,642...9,578,310
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO (MGI:MGI:3760575|PMID:17954568) RGD PMID:17954568 MGI:MGI:3760575 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 ISO (MGI:MGI:5562517|PMID:23871208) RGD PMID:23871208 MGI:MGI:5562517 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348
JBrowse link
G Riok3 RIO kinase 3 ISO (PMID:24807708) RGD PMID:24807708 NCBI chr18:3,565,166...3,590,739
Ensembl chr18:3,565,166...3,590,739
JBrowse link
G Rnf135 ring finger protein 135 ISO
ISS
(PMID:19017631)
GO_REF:0000024
RGD
UniProt
PMID:19017631 GO_REF:0000024 NCBI chr10:67,531,989...67,551,237 JBrowse link
G Tbk1 TANK-binding kinase 1 ISO (PMID:16127453)
MGI:MGI:3046789 (MGI:MGI:3530402|PMID:15661922)
RGD PMID:15661922, PMID:16127453 MGI:MGI:3530402 NCBI chr 7:63,655,247...63,687,978
Ensembl chr 7:63,655,247...63,687,978
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 ISO MGI:MGI:2679794|MGI:MGI:3029019 (MGI:MGI:2669022|PMID:12855817), (MGI:MGI:2670551|PMID:12872135) RGD PMID:12855817, PMID:12872135 MGI:MGI:2669022, MGI:MGI:2670551 NCBI chr 9:10,780,185...10,790,280 JBrowse link
G Tlr2 toll-like receptor 2 ISO (MGI:MGI:4456948|PMID:15356140) RGD PMID:15356140 MGI:MGI:4456948 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr3 toll-like receptor 3 ISO (MGI:MGI:4456948|PMID:15356140)
(PMID:12054664), (PMID:16286015)
RGD PMID:12054664, PMID:15356140, PMID:16286015 MGI:MGI:4456948 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tlr4 toll-like receptor 4 ISO
IEA
MGI:MGI:1860885 (MGI:MGI:3530402|PMID:15661922), (MGI:MGI:4456948|PMID:15356140)
GO_REF:0000107
RGD
Ensembl
PMID:15356140, PMID:15661922 GO_REF:0000107, MGI:MGI:3530402, MGI:MGI:4456948 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr7 toll-like receptor 7 ISO (PMID:16286015) RGD PMID:16286015 NCBI chr  X:28,486,836...28,513,004
Ensembl chr  X:28,486,869...28,512,957
JBrowse link
G Tlr8 toll-like receptor 8 ISO (PMID:16286015) RGD PMID:16286015 NCBI chr  X:28,539,158...28,562,803
Ensembl chr  X:28,539,158...28,562,803
JBrowse link
G Tlr9 toll-like receptor 9 ISO (MGI:MGI:4456948|PMID:15356140)
(PMID:16286015)
RGD PMID:15356140, PMID:16286015 MGI:MGI:4456948 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 ISO (MGI:MGI:5619432|PMID:23776228) RGD PMID:23776228 MGI:MGI:5619432 NCBI chr11:62,014,925...62,561,113
Ensembl chr11:62,014,925...62,451,184
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 ISO (PMID:21102435) RGD PMID:21102435 NCBI chr 4:66,012,111...66,062,160
Ensembl chr 4:66,011,915...66,062,089
JBrowse link
G Zfp64 zinc finger protein 64 ISO (MGI:MGI:5619431|PMID:23857586) RGD PMID:23857586 MGI:MGI:5619431 NCBI chr 3:165,713,070...165,741,932
Ensembl chr 3:165,713,020...165,741,967
JBrowse link
regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf216 ring finger protein 216 ISO (PMID:19893624) RGD PMID:19893624 NCBI chr12:13,508,429...13,631,689
Ensembl chr12:13,508,429...13,632,304
JBrowse link
G Tirap TIR domain containing adaptor protein ISO (MGI:MGI:4942245|PMID:14630816) RGD PMID:14630816 MGI:MGI:4942245 NCBI chr 8:36,382,029...36,399,625
Ensembl chr 8:36,385,353...36,388,224
JBrowse link
G Traf3 Tnf receptor-associated factor 3 ISO (MGI:MGI:4839450|PMID:16306937) RGD PMID:16306937 MGI:MGI:4839450 NCBI chr 6:135,610,698...135,720,247
Ensembl chr 6:135,610,743...135,718,564
JBrowse link
G Trim38 tripartite motif containing 38 ISO (MGI:MGI:5441682|PMID:22539786) RGD PMID:22539786 MGI:MGI:5441682 NCBI chr17:43,600,006...43,607,879 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    multicellular organismal process 9068
      cytokine production 838
        type I interferon production 91
          interferon-beta production 54
            negative regulation of interferon-beta production 16
            positive regulation of interferon-beta production 34
            regulation of interferon-beta production + 53
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          gene expression 6294
            cytokine production 838
              type I interferon production 91
                interferon-beta production 54
                  negative regulation of interferon-beta production 16
                  positive regulation of interferon-beta production 34
                  regulation of interferon-beta production + 53
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.