ONTOLOGY REPORT - ANNOTATIONS


Term:interleukin-10 production
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Accession:GO:0032613 term browser browse the term
Definition:The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: IL-10 production


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interleukin-10 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:1624291
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:1624291
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1624291
RGD:1600115
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1624291
RGD:1600115
G Tnfsf18 TNF superfamily member 18 JBrowse link 13 79,378,412 79,388,687 RGD:1624291
interleukin-10 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
RGD:1600115
G Isg15 ISG15 ubiquitin-like modifier JBrowse link 5 173,624,862 173,629,124 RGD:1600115
RGD:1624291
negative regulation of interleukin-10 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trib2 tribbles pseudokinase 2 JBrowse link 6 41,016,722 41,040,972 RGD:1624291
RGD:1600115
G Tyrobp Tyro protein tyrosine kinase binding protein JBrowse link 1 88,875,370 88,879,305 RGD:1624291
negative regulation of interleukin-10 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1600115
RGD:1624291
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1624291
RGD:1600115
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:1600115
RGD:1624291
G Epx eosinophil peroxidase JBrowse link 10 75,160,690 75,171,774 RGD:1624291
RGD:1600115
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
RGD:1600115
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:1624291
RGD:1600115
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:1624291
RGD:1600115
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:1624291
RGD:1600115
G Il23r interleukin 23 receptor JBrowse link 4 98,203,788 98,306,729 RGD:1624291
RGD:1600115
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:1624291
RGD:1600115
G Mir98 microRNA 98 JBrowse link X 21,583,875 21,583,982 RGD:1624291
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:1600115
RGD:1624291
G Pdcd1lg2 programmed cell death 1 ligand 2 JBrowse link 1 247,562,202 247,629,279 RGD:1624291
RGD:1600115
G Prg2 proteoglycan 2 JBrowse link 3 72,385,678 72,389,245 RGD:1624291
RGD:1600115
G Vsir V-set immunoregulatory receptor JBrowse link 20 29,897,543 29,923,381 RGD:1624291
negative regulation of interleukin-10 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd84 CD84 molecule JBrowse link 13 90,241,369 90,283,625 RGD:1624291
G Tnfrsf21 TNF receptor superfamily member 21 JBrowse link 9 20,546,159 20,621,051 RGD:1624291
RGD:13792537
RGD:1600115
G Tnfrsf9 TNF receptor superfamily member 9 JBrowse link 5 168,009,245 168,035,813 RGD:1624291
positive regulation of interleukin-10 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl3 BCL3, transcription coactivator JBrowse link 1 80,730,758 80,745,273 RGD:1624291
G Irf4 interferon regulatory factor 4 JBrowse link 17 34,886,746 34,905,191 RGD:1624291
RGD:1600115
positive regulation of interleukin-10 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:1600115
RGD:1624291
G Cd34 CD34 molecule JBrowse link 13 113,691,842 113,711,259 RGD:1624291
RGD:1600115
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:2313421
RGD:1624291
RGD:1600115
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:1624291
G Cd83 CD83 molecule JBrowse link 17 24,416,651 24,435,790 RGD:1624291
RGD:1600115
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
RGD:1600115
G Hgf hepatocyte growth factor JBrowse link 4 15,435,460 15,505,377 RGD:1624291
RGD:1600115
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1624291
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:1624291
RGD:1600115
G Il20rb interleukin 20 receptor subunit beta JBrowse link 8 108,745,906 108,778,561 RGD:1624291
RGD:1600115
G Il21 interleukin 21 JBrowse link 2 123,965,021 123,972,356 RGD:1624291
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:1624291
RGD:1600115
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:2317299
G Inava innate immunity activator JBrowse link 13 53,088,438 53,108,713 RGD:1624291
RGD:1600115
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
G Pibf1 progesterone immunomodulatory binding factor 1 JBrowse link 15 83,494,110 83,663,202 RGD:1624291
RGD:1600115
G Sash3 SAM and SH3 domain containing 3 JBrowse link X 134,979,637 134,994,351 RGD:1624291
RGD:1600115
G Tigit T cell immunoreceptor with Ig and ITIM domains JBrowse link 11 61,966,780 61,987,749 RGD:1624291
RGD:13792537
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:7241093
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1600115
RGD:1624291
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
RGD:1600115
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
RGD:1600115
G Trem2 triggering receptor expressed on myeloid cells 2 JBrowse link 9 14,611,541 14,618,076 RGD:1624291
G Tslp thymic stromal lymphopoietin JBrowse link 18 25,613,601 25,618,066 RGD:1624291
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator JBrowse link 8 116,318,963 116,322,181 RGD:1624291
RGD:1600115
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
positive regulation of interleukin-10 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1624291
RGD:1600115
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Lilra5 leukocyte immunoglobulin like receptor A5 JBrowse link 1 73,655,767 73,682,232 RGD:1624291
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:1624291
RGD:1600115
G Ptger4 prostaglandin E receptor 4 JBrowse link 2 54,951,625 54,966,470 RGD:10043380
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
RGD:1600115
regulation of interleukin-10 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd47 Cd47 molecule JBrowse link 11 53,511,485 53,575,754 RGD:1624291
regulation of interleukin-10 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:1624291

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  biological_process 17896
    multicellular organismal process 8524
      cytokine production 771
        interleukin-10 production 60
          interleukin-10 biosynthetic process + 4
          interleukin-10 secretion + 12
          negative regulation of interleukin-10 production + 21
          positive regulation of interleukin-10 production + 35
          regulation of interleukin-10 production + 55
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.