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ONTOLOGY REPORT - ANNOTATIONS


Term:interleukin-17 production
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Accession:GO:0032620 term browser browse the term
Definition:The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: CTLA-8 production;   Cytotoxic T-lymphocyte-associated antigen 8 production;   IL-17 production
 narrow_synonym: interleukin-17 biosynthetic process;   interleukin-17 secretion
 alt_id: GO:0042235;   GO:0072615


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interleukin-17 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir301a microRNA 301a ISO (MGI:MGI:5426073|PMID:22517757) RGD PMID:22517757 MGI:MGI:5426073 NCBI chr10:74,417,746...74,417,845
Ensembl chr10:74,417,746...74,417,845
JBrowse link
G Mr1 major histocompatibility complex, class I-related ISO
IEA
MGI:MGI:3664578 (MGI:MGI:4888422|PMID:21190736)
GO_REF:0000107
RGD
Ensembl
PMID:21190736 GO_REF:0000107, MGI:MGI:4888422 NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 ISO
IEA
(PMID:21242261)
GO_REF:0000107
RGD
Ensembl
PMID:21242261 GO_REF:0000107 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Olr292 olfactory receptor 292 IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:212,714,092...212,886,388
Ensembl chr 1:212,885,464...212,886,381
JBrowse link
G Phb prohibitin ISO
ISS
(PMID:31899195)
GO_REF:0000024
RGD
UniProt
PMID:31899195 GO_REF:0000024 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878
JBrowse link
G Rftn1 raftlin lipid raft linker 1 ISO (MGI:MGI:3850290|PMID:19414744) RGD PMID:19414744 MGI:MGI:3850290 NCBI chr 9:12,740,885...12,942,358
Ensembl chr 9:12,740,885...12,942,358
JBrowse link
G Rorc RAR-related orphan receptor C ISO (MGI:MGI:3795336|PMID:18368049), (MGI:MGI:5621075|PMID:25470037) RGD PMID:18368049, PMID:25470037 MGI:MGI:3795336, MGI:MGI:5621075 NCBI chr 2:195,612,471...195,636,797
Ensembl chr 2:195,617,021...195,637,630
JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B ISO (MGI:MGI:5449456|PMID:23105140) RGD PMID:23105140 MGI:MGI:5449456 NCBI chr 2:188,704,989...188,719,674
Ensembl chr 2:188,704,687...188,718,704
JBrowse link
negative regulation of interleukin-17 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 ISO
IEA
(MGI:MGI:5810834|PMID:27214549)
GO_REF:0000107
RGD
Ensembl
PMID:27214549 GO_REF:0000107, MGI:MGI:5810834 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 ISO
IEA
(PMID:24038088)
GO_REF:0000107
RGD
Ensembl
PMID:24038088 GO_REF:0000107 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Foxp3 forkhead box P3 ISO (PMID:18368049)
(MGI:MGI:3795336|PMID:18368049)
RGD PMID:18368049 MGI:MGI:3795336 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Ifng interferon gamma ISO (PMID:18501882) RGD PMID:18501882 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il12a interleukin 12A ISO
IEA
(PMID:16482511)
GO_REF:0000107
RGD
Ensembl
PMID:16482511 GO_REF:0000107 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B ISO (PMID:16482511) RGD PMID:16482511 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha ISO UniProtKB:P35951 (MGI:MGI:5581894|PMID:22927332) RGD PMID:22927332 MGI:MGI:5581894 NCBI chr19:25,151,835...25,163,995
Ensembl chr19:25,149,897...25,164,086
JBrowse link
G Il36rn interleukin 36 receptor antagonist ISO (PMID:23147407) RGD PMID:23147407 NCBI chr 3:1,385,256...1,392,275
Ensembl chr 3:1,385,654...1,392,275
JBrowse link
G Mir125a microRNA 125a IMP RGD PMID:30972208 RGD:26884458 NCBI chr 1:59,704,827...59,704,911
Ensembl chr 1:59,704,827...59,704,911
JBrowse link
G Nckap1l NCK associated protein 1 like ISO
ISS
(MGI:MGI:3818191|PMID:19015308)
GO_REF:0000024
RGD
UniProt
PMID:19015308 GO_REF:0000024, MGI:MGI:3818191 NCBI chr 7:145,068,239...145,113,507
Ensembl chr 7:145,068,286...145,113,507
JBrowse link
G Otud5 OTU deubiquitinase 5 ISO MGI:MGI:1918040|MGI:MGI:2386448|MGI:MGI:5752247 (MGI:MGI:5621075|PMID:25470037) RGD PMID:25470037 MGI:MGI:5621075 NCBI chr  X:15,471,212...15,504,372
Ensembl chr  X:15,471,211...15,504,165
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO (MGI:MGI:5621075|PMID:25470037) RGD PMID:25470037 MGI:MGI:5621075 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Prnp prion protein ISO (MGI:MGI:4943618|PMID:20145049) RGD PMID:20145049 MGI:MGI:4943618 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO (MGI:MGI:3795336|PMID:18368049) RGD PMID:18368049 MGI:MGI:3795336 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tlr2 toll-like receptor 2 ISO MGI:MGI:2178675 (MGI:MGI:3611539|PMID:16239543) RGD PMID:16239543 MGI:MGI:3611539 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 IEA
ISO
GO_REF:0000107
(MGI:MGI:3773594|PMID:18203139), (MGI:MGI:4421230|PMID:20051628)
Ensembl
RGD
PMID:18203139, PMID:20051628 GO_REF:0000107, MGI:MGI:3773594, MGI:MGI:4421230 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnfsf4 TNF superfamily member 4 ISO (PMID:18501882) RGD PMID:18501882 NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator ISO MGI:MGI:3706236 (MGI:MGI:5518492|PMID:24042119) RGD PMID:24042119 MGI:MGI:5518492 NCBI chr 8:116,318,963...116,322,181
Ensembl chr 8:116,318,963...116,322,181
JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 ISO MGI:MGI:1859615 (MGI:MGI:5621075|PMID:25470037) RGD PMID:25470037 MGI:MGI:5621075 NCBI chr 7:76,789,110...76,835,517
NCBI chr 7:76,839,661...76,907,441
Ensembl chr 7:76,789,531...76,853,840
JBrowse link
G Vsir V-set immunoregulatory receptor ISO (PMID:24691993) RGD PMID:24691993 NCBI chr20:29,897,543...29,923,381
Ensembl chr20:29,897,594...29,919,998
JBrowse link
positive regulation of interleukin-17 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A ISO (MGI:MGI:5780752|PMID:27022145) RGD PMID:27022145 MGI:MGI:5780752 NCBI chr 9:42,871,907...42,886,725
Ensembl chr 9:42,871,950...42,884,855
JBrowse link
G Ccl1 C-C motif chemokine ligand 1 ISO (PMID:28972028) RGD PMID:28972028 NCBI chr10:69,534,976...69,537,836
Ensembl chr10:69,534,933...69,537,882
JBrowse link
G Il12b interleukin 12B ISO (PMID:16482511), (PMID:16751425), (PMID:17888176) RGD PMID:16482511, PMID:16751425, PMID:17888176 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il15 interleukin 15 ISO (PMID:16482511) RGD PMID:16482511 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Il18 interleukin 18 ISO
IEA
(PMID:16482511)
GO_REF:0000107
RGD
Ensembl
PMID:16482511 GO_REF:0000107 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il2 interleukin 2 ISO (PMID:16482511) RGD PMID:16482511 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il21 interleukin 21 ISO (PMID:16482511) RGD PMID:16482511 NCBI chr 2:123,965,021...123,972,356
Ensembl chr 2:123,965,021...123,972,356
JBrowse link
G Il23a interleukin 23 subunit alpha ISO (PMID:16482511), (PMID:16751425), (PMID:17888176) RGD PMID:16482511, PMID:16751425, PMID:17888176 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il6 interleukin 6 ISO (MGI:MGI:6294413|PMID:25362566) RGD PMID:25362566 MGI:MGI:6294413 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ly9 lymphocyte antigen 9 ISO (PMID:22184727) RGD PMID:22184727 NCBI chr13:90,002,779...90,022,346
Ensembl chr13:90,002,783...90,022,269
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ISO (MGI:MGI:3773594|PMID:18203139) RGD PMID:18203139 MGI:MGI:3773594 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO (PMID:17919942) RGD PMID:17919942 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Osm oncostatin M ISO (PMID:28972028) RGD PMID:28972028 NCBI chr14:84,457,487...84,469,426
Ensembl chr14:84,465,515...84,470,409
JBrowse link
G Prkcq protein kinase C, theta IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:3769226|PMID:16493044)
Ensembl
UniProt
RGD
PMID:16493044 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3769226 NCBI chr17:70,971,915...71,105,286
Ensembl chr17:70,971,915...71,105,286
JBrowse link
G Slamf6 SLAM family member 6 ISO (PMID:22184727) RGD PMID:22184727 NCBI chr13:90,300,160...90,321,781
Ensembl chr13:90,301,006...90,322,457
JBrowse link
G Slc7a5 solute carrier family 7 member 5 ISO (PMID:24038088) RGD PMID:24038088 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Sphk1 sphingosine kinase 1 IMP PMID:28284343 UniProt PMID:28284343 RGD:14397556 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO
ISS
(PMID:18453574)
GO_REF:0000024
(MGI:MGI:3851279|PMID:19501566)
RGD
UniProt
PMID:18453574, PMID:19501566 GO_REF:0000024, MGI:MGI:3851279 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    multicellular organismal process 9068
      cytokine production 838
        interleukin-17 production 44
          interleukin-17A production + 0
          interleukin-17F production 0
          negative regulation of interleukin-17 production + 20
          positive regulation of interleukin-17 production + 18
          regulation of interleukin-17 production + 36
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          gene expression 6294
            cytokine production 838
              interleukin-17 production 44
                interleukin-17A production + 0
                interleukin-17F production 0
                negative regulation of interleukin-17 production + 20
                positive regulation of interleukin-17 production + 18
                regulation of interleukin-17 production + 36
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.