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ONTOLOGY REPORT - ANNOTATIONS


Term:interleukin-23 production
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Accession:GO:0032627 term browser browse the term
Definition:The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: IL-23 production
 narrow_synonym: interleukin-23 biosynthetic process;   interleukin-23 secretion
 alt_id: GO:0042240;   GO:0072621


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negative regulation of interleukin-23 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rac1 Rac family small GTPase 1 ISO (PMID:16982892) RGD PMID:16982892 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Tlr4 toll-like receptor 4 ISO
IEA
(MGI:MGI:3773594|PMID:18203139)
GO_REF:0000107
RGD
Ensembl
PMID:18203139 GO_REF:0000107, MGI:MGI:3773594 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
positive regulation of interleukin-23 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2 colony stimulating factor 2 ISO (PMID:20027291) RGD PMID:20027291 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Ifng interferon gamma ISO (PMID:20027291) RGD PMID:20027291 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il17a interleukin 17A ISO
IEA
(PMID:21145111)
GO_REF:0000107
RGD
Ensembl
PMID:21145111 GO_REF:0000107 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il17ra interleukin 17 receptor A ISO (PMID:21145111) RGD PMID:21145111 NCBI chr 4:152,995,865...153,018,394
Ensembl chr 4:152,995,865...153,018,394
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ISO (MGI:MGI:3773594|PMID:18203139) RGD PMID:18203139 MGI:MGI:3773594 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
regulation of interleukin-23 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 ISO (MGI:MGI:3795336|PMID:18368049) RGD PMID:18368049 MGI:MGI:3795336 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    multicellular organismal process 9068
      cytokine production 838
        interleukin-23 production 8
          negative regulation of interleukin-23 production 2
          positive regulation of interleukin-23 production 5
          regulation of interleukin-23 production + 8
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          gene expression 6294
            cytokine production 838
              interleukin-23 production 8
                negative regulation of interleukin-23 production 2
                positive regulation of interleukin-23 production 5
                regulation of interleukin-23 production + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.