ONTOLOGY REPORT - ANNOTATIONS


Term:interleukin-8 production
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Accession:GO:0032637 term browser browse the term
Definition:The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: IL-8 production


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interleukin-8 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrc19 leucine rich repeat containing 19 JBrowse link 4 94,636,653 94,650,144 RGD:2290270
interleukin-8 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nod1 nucleotide-binding oligomerization domain containing 1 JBrowse link 6 54,923,942 54,972,672 RGD:2290270
interleukin-8 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chil1 chitinase-like 1 JBrowse link 1 134,182,170 134,190,031 RGD:2290270
G Lep leptin JBrowse link 6 29,060,195 29,073,877 RGD:2290270
G Nos2 nitric oxide synthase 2, inducible JBrowse link 11 78,920,787 78,960,232 RGD:2290270
G Rab1a RAB1A, member RAS oncogene family JBrowse link 11 20,201,602 20,226,856 RGD:2290270
negative regulation of interleukin-8 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl3 B cell leukemia/lymphoma 3 JBrowse link 7 19,808,462 19,822,767 RGD:2290270
G Elane elastase, neutrophil expressed JBrowse link 10 79,886,312 79,888,216 RGD:2290270
G Klf4 Kruppel-like factor 4 (gut) JBrowse link 4 55,527,137 55,532,475 RGD:2290270
G Map2k5 mitogen-activated protein kinase kinase 5 JBrowse link 9 63,163,768 63,381,682 RGD:2290270
negative regulation of interleukin-8 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrb1 arrestin, beta 1 JBrowse link 7 99,535,486 99,606,772 RGD:2290270
G Bpi bactericidal permeablility increasing protein JBrowse link 2 158,258,063 158,284,533 RGD:2290270
G Cactin cactin, spliceosome C complex subunit JBrowse link 10 81,321,103 81,326,251 RGD:2290270
G Otud7b OTU domain containing 7B JBrowse link 3 96,104,510 96,161,129 RGD:2290270
G Tlr9 toll-like receptor 9 JBrowse link 9 106,222,598 106,226,876 RGD:2290270
negative regulation of interleukin-8 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 19 20,373,434 20,390,671 RGD:2290270
G Anxa4 annexin A4 JBrowse link 6 86,736,840 86,793,593 RGD:2290270
G Mapkbp1 mitogen-activated protein kinase binding protein 1 JBrowse link 2 119,972,387 120,027,403 RGD:2290270
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) JBrowse link 3 103,856,802 103,912,252 RGD:2290270
G Ssc5d scavenger receptor cysteine rich family, 5 domains JBrowse link 7 4,925,127 4,944,828 RGD:2290270
G Tlr6 toll-like receptor 6 JBrowse link 5 64,952,030 64,971,140 RGD:2290270
positive regulation of interleukin-8 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa2 apolipoprotein A-II JBrowse link 1 171,221,564 171,226,379 RGD:2290270
G Bcl10 B cell leukemia/lymphoma 10 JBrowse link 3 145,924,262 145,934,366 RGD:2290270
G Elane elastase, neutrophil expressed JBrowse link 10 79,886,312 79,888,216 RGD:2290270
G Prg3 proteoglycan 3 JBrowse link 2 84,988,196 84,996,559 RGD:2290270
G Tlr4 toll-like receptor 4 JBrowse link 4 66,827,551 66,846,581 RGD:2290270
G Tlr7 toll-like receptor 7 JBrowse link X 167,304,926 167,330,574 RGD:2290270
G Tlr8 toll-like receptor 8 JBrowse link X 167,241,123 167,264,329 RGD:2290270
G Tlr9 toll-like receptor 9 JBrowse link 9 106,222,598 106,226,876 RGD:2290270
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:2290270
positive regulation of interleukin-8 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 16 23,146,536 23,157,968 RGD:2290270
G Afap1l2 actin filament associated protein 1-like 2 JBrowse link 19 56,912,354 57,008,591 RGD:2290270
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 10 127,290,793 127,296,291 RGD:2290270
G Ddx58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 JBrowse link 4 40,203,777 40,239,825 RGD:2290270
G Fadd Fas (TNFRSF6)-associated via death domain JBrowse link 7 144,578,323 144,582,436 RGD:2290270
G Gdf2 growth differentiation factor 2 JBrowse link 14 33,941,039 33,947,198 RGD:2290270
G Il17d interleukin 17D JBrowse link 14 57,524,829 57,543,166 RGD:2290270
G Il18 interleukin 18 JBrowse link 9 50,554,705 50,581,841 RGD:2290270
G Il1b interleukin 1 beta JBrowse link 2 129,363,842 129,371,170 RGD:2290270
G Lbp lipopolysaccharide binding protein JBrowse link 2 158,306,493 158,332,852 RGD:2290270
G Mavs mitochondrial antiviral signaling protein JBrowse link 2 131,234,063 131,248,025 RGD:2290270
G Myd88 myeloid differentiation primary response gene 88 JBrowse link 9 119,335,988 119,340,040 RGD:2290270
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 8 88,647,280 88,688,474 RGD:2290270
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:2290270
G Prkd2 protein kinase D2 JBrowse link 7 16,842,902 16,870,461 RGD:2290270
G Ptger4 prostaglandin E receptor 4 (subtype EP4) JBrowse link 15 5,233,399 5,244,187 RGD:2290270
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 JBrowse link 13 34,002,363 34,035,170 RGD:2290270
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 JBrowse link 5 137,061,504 137,072,272 RGD:2290270
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein JBrowse link 9 35,184,391 35,200,291 RGD:2290270
G Tlr2 toll-like receptor 2 JBrowse link 3 83,836,272 83,841,824 RGD:2290270
G Tlr3 toll-like receptor 3 JBrowse link 8 45,395,665 45,411,949 RGD:2290270
G Tlr4 toll-like receptor 4 JBrowse link 4 66,827,551 66,846,581 RGD:2290270
G Tlr5 toll-like receptor 5 JBrowse link 1 182,954,752 182,976,044 RGD:2290270
G Tlr7 toll-like receptor 7 JBrowse link X 167,304,926 167,330,574 RGD:2290270
G Tlr9 toll-like receptor 9 JBrowse link 9 106,222,598 106,226,876 RGD:2290270
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:2290270
G Zfp580 zinc finger protein 580 JBrowse link 7 5,051,532 5,053,723 RGD:2290270
positive regulation of interleukin-8 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd14 CD14 antigen JBrowse link 18 36,725,064 36,726,815 RGD:2290270
G Cd2 CD2 antigen JBrowse link 3 101,275,908 101,287,939 RGD:2290270
G Cd244a CD244 molecule A JBrowse link 1 171,558,713 171,585,316 RGD:2290270
G F2r coagulation factor II (thrombin) receptor JBrowse link 13 95,601,789 95,618,433 RGD:2290270
G F2rl1 coagulation factor II (thrombin) receptor-like 1 JBrowse link 13 95,511,718 95,525,240 RGD:2290270
G Fcnb ficolin B JBrowse link 2 28,076,479 28,084,903 RGD:2290270
G Ffar2 free fatty acid receptor 2 JBrowse link 7 30,818,031 30,823,775 RGD:2290270
G Hyal2 hyaluronoglucosaminidase 2 JBrowse link 9 107,567,886 107,572,778 RGD:2290270
G Nlrp10 NLR family, pyrin domain containing 10 JBrowse link 7 108,921,853 108,930,158 RGD:2290270
G Pycard PYD and CARD domain containing JBrowse link 7 127,991,373 127,993,867 RGD:2290270
G Tlr1 toll-like receptor 1 JBrowse link 5 64,924,680 64,933,589 RGD:2290270
G Tlr2 toll-like receptor 2 JBrowse link 3 83,836,272 83,841,824 RGD:2290270
G Wnt5a wingless-type MMTV integration site family, member 5A JBrowse link 14 28,505,473 28,527,448 RGD:2290270
regulation of interleukin-8 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il17f interleukin 17F JBrowse link 1 20,777,146 20,785,274 RGD:2290270
regulation of interleukin-8 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 1 138,062,859 138,175,756 RGD:2290270
regulation of interleukin-8 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C5ar2 complement component 5a receptor 2 JBrowse link 7 16,234,585 16,244,154 RGD:2290270
G Crp C-reactive protein, pentraxin-related JBrowse link 1 172,698,056 172,699,966 RGD:2290270
G Ssc5d scavenger receptor cysteine rich family, 5 domains JBrowse link 7 4,925,127 4,944,828 RGD:2290270

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  biological_process 22959
    multicellular organismal process 8143
      cytokine production 754
        interleukin-8 production 67
          interleukin-8 biosynthetic process + 14
          interleukin-8 secretion + 25
          negative regulation of interleukin-8 production + 15
          positive regulation of interleukin-8 production + 44
          regulation of interleukin-8 production + 61
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.