ONTOLOGY REPORT - ANNOTATIONS


Term:interleukin-8 production
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Accession:GO:0032637 term browser browse the term
Definition:The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: IL-8 production


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interleukin-8 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrc19 leucine rich repeat containing 19 JBrowse link 5 113,614,164 113,626,834 RGD:1600115
RGD:1624291
G Pla2g1b phospholipase A2 group IB JBrowse link 12 46,879,346 46,890,234 RGD:1624291
interleukin-8 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nod1 nucleotide-binding oligomerization domain containing 1 JBrowse link 4 85,123,965 85,175,206 RGD:1624291
RGD:1600115
interleukin-8 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chi3l1 chitinase 3 like 1 JBrowse link 13 51,022,844 51,030,797 RGD:1624291
RGD:1600115
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:1624291
RGD:1600115
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:1600115
RGD:1624291
G Rab1a RAB1A, member RAS oncogene family JBrowse link 14 104,475,082 104,500,176 RGD:1624291
RGD:1600115
negative regulation of interleukin-8 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl3 BCL3, transcription coactivator JBrowse link 1 80,730,758 80,745,273 RGD:1624291
RGD:1600115
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:1624291
RGD:1600115
G Klf4 Kruppel like factor 4 JBrowse link 5 72,283,311 72,287,669 RGD:1624291
RGD:1600115
G Map2k5 mitogen activated protein kinase kinase 5 JBrowse link 8 68,055,976 68,282,656 RGD:8553940
negative regulation of interleukin-8 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
RGD:1600115
G Bpi bactericidal/permeability-increasing protein JBrowse link 3 154,741,627 154,768,584 RGD:1624291
RGD:1600115
G Cactin cactin, spliceosome C complex subunit JBrowse link 7 11,258,526 11,266,509 RGD:1624291
RGD:1600115
G Cd33 CD33 molecule JBrowse link 1 98,388,811 98,403,539 RGD:1624291
G Otud7b OTU deubiquitinase 7B JBrowse link 2 198,231,353 198,302,220 RGD:1624291
RGD:1600115
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
negative regulation of interleukin-8 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:1624291
RGD:13792537
G Anxa4 annexin A4 JBrowse link 4 118,538,775 118,595,591 RGD:1624291
RGD:1600115
G Mapkbp1 mitogen activated protein kinase binding protein 1 JBrowse link 3 111,767,126 111,817,103 RGD:1624291
RGD:1600115
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:1624291
RGD:1600115
G Ssc5d scavenger receptor cysteine rich family member with 5 domains JBrowse link 1 72,443,750 72,462,293 RGD:1624291
RGD:1600115
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:1624291
RGD:1600115
G Tmsb4x thymosin beta 4, X-linked JBrowse link X 28,593,405 28,617,267 RGD:1624291
positive regulation of interleukin-8 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa2 apolipoprotein A2 JBrowse link 13 89,596,872 89,598,805 RGD:1624291
RGD:1600115
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:1624291
RGD:1600115
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:1624291
RGD:1600115
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 JBrowse link 3 72,395,194 72,401,254 RGD:1624291
RGD:1600115
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:1600115
G Tlr7 toll-like receptor 7 JBrowse link X 28,486,836 28,513,004 RGD:1624291
RGD:13792537
G Tlr8 toll-like receptor 8 JBrowse link X 28,539,158 28,562,803 RGD:1624291
RGD:13792537
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:13792537
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
positive regulation of interleukin-8 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:1624291
RGD:1600115
G Afap1l2 actin filament associated protein 1-like 2 JBrowse link 1 277,730,760 277,827,299 RGD:1624291
RGD:13792537
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:1624291
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:1600115
RGD:1624291
G Ddx58 DEXD/H-box helicase 58 JBrowse link 5 56,486,584 56,536,898 RGD:1624291
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:1624291
RGD:1600115
G Gdf2 growth differentiation factor 2 JBrowse link 16 10,267,510 10,293,545 RGD:1624291
RGD:1600115
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:10054071
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:1624291
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1624291
G Il17d interleukin 17D JBrowse link 15 37,790,211 37,807,653 RGD:1624291
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:4889457
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:1624291
RGD:1600115
G Mavs mitochondrial antiviral signaling protein JBrowse link 3 123,776,147 123,790,572 RGD:1624291
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:1624291
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
RGD:1600115
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Prkd2 protein kinase D2 JBrowse link 1 78,767,911 78,796,223 RGD:1624291
RGD:1600115
G Ptger4 prostaglandin E receptor 4 JBrowse link 2 54,951,625 54,966,470 RGD:10003098
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link 17 31,537,580 31,569,904 RGD:1624291
RGD:1600115
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:1624291
RGD:1600115
G Tirap TIR domain containing adaptor protein JBrowse link 8 36,382,029 36,399,625 RGD:1624291
RGD:1600115
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1624291
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1624291
RGD:1600115
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
G Tlr5 toll-like receptor 5 JBrowse link 13 101,364,784 101,385,764 RGD:1624291
G Tlr7 toll-like receptor 7 JBrowse link X 28,486,836 28,513,004 RGD:1624291
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Zfp580 zinc finger protein 580 JBrowse link 1 72,338,468 72,340,636 RGD:1624291
RGD:1600115
positive regulation of interleukin-8 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:1624291
RGD:13792537
G Cd2 Cd2 molecule JBrowse link 2 203,666,706 203,680,073 RGD:1624291
RGD:1600115
G Cd244 CD244 molecule JBrowse link 13 89,959,091 89,995,993 RGD:1624291
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:1600115
RGD:1624291
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1600115
RGD:1624291
G Fcna ficolin A JBrowse link 3 2,850,006 2,853,230 RGD:1600115
G Fcnb ficolin B JBrowse link 3 6,617,816 6,626,193 RGD:1624291
RGD:1600115
G Ffar2 free fatty acid receptor 2 JBrowse link 1 89,268,197 89,271,942 RGD:1624291
RGD:1600115
G Hyal2 hyaluronidase 2 JBrowse link 8 116,324,062 116,328,978 RGD:1600115
RGD:1624291
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Nlrp10 NLR family, pyrin domain containing 10 JBrowse link 1 173,521,412 173,528,969 RGD:1624291
RGD:1600115
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
RGD:1600115
G Tlr1 toll-like receptor 1 JBrowse link 14 45,062,662 45,065,014 RGD:1624291
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
regulation of interleukin-8 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il17f interleukin 17F JBrowse link 9 26,885,702 26,897,219 RGD:1600115
RGD:1624291
regulation of interleukin-8 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1600115
RGD:1624291
regulation of interleukin-8 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C5ar2 complement component 5a receptor 2 JBrowse link 1 78,165,155 78,183,426 RGD:1624291
RGD:1600115
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:1624291
RGD:1600115
G Ssc5d scavenger receptor cysteine rich family member with 5 domains JBrowse link 1 72,443,750 72,462,293 RGD:1624291

Term paths to the root
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Term Annotations click to browse term
  biological_process 17926
    multicellular organismal process 8539
      cytokine production 775
        interleukin-8 production 76
          interleukin-8 biosynthetic process + 14
          interleukin-8 secretion + 28
          negative regulation of interleukin-8 production + 17
          positive regulation of interleukin-8 production + 50
          regulation of interleukin-8 production + 69
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.